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Items: 1 to 50 of 201

1.

Anti-tumor T-cell homeostatic activation is uncoupled from homeostatic inhibition by checkpoint blockade.

Marshall N, Hutchinson K, Marron TU, Aleynick M, Hammerich L, Upadhyay R, Svensson-Arvelund J, Brown BD, Merad M, Brody JD.

Cancer Discov. 2019 Aug 2. pii: CD-19-0391. doi: 10.1158/2159-8290.CD-19-0391. [Epub ahead of print]

PMID:
31375522
2.

The Kids4Dementia education program is effective in improving children's attitudes towards dementia.

Baker JR, Goodenough B, Jeon YH, Bryden C, Hutchinson K, Low LF.

Dementia (London). 2019 Jul;18(5):1777-1789. doi: 10.1177/1471301217731385. Epub 2018 Oct 23. No abstract available.

PMID:
31319740
3.

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

Castillo J, Wu E, Lowe C, Srinivasan S, McCord R, Wagle MC, Jayakar S, Edick MG, Eastham-Anderson J, Liu B, Hutchinson KE, Jones W, Stokes MP, Tarighat SS, Holcomb T, Glibicky A, Romero FA, Magnuson S, Huang SA, Plaks V, Giltnane JM, Lackner MR, Mounir Z.

Cancer Res. 2019 Aug 1;79(15):3916-3927. doi: 10.1158/0008-5472.CAN-18-3622. Epub 2019 Jun 10.

PMID:
31182547
4.

Pharmacology beyond the patient - The environmental risks of human drugs.

Gunnarsson L, Snape JR, Verbruggen B, Owen SF, Kristiansson E, Margiotta-Casaluci L, Österlund T, Hutchinson K, Leverett D, Marks B, Tyler CR.

Environ Int. 2019 Aug;129:320-332. doi: 10.1016/j.envint.2019.04.075. Epub 2019 May 28.

5.

Correction: Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER+ Breast Cancer.

Formisano L, Stauffer KM, Young CD, Bhola NE, Guerrero-Zotano AL, Jansen VM, Estrada MM, Hutchinson KE, Giltnane JM, Schwarz LJ, Lu Y, Balko JM, Deas O, Cairo S, Judde JG, Mayer IA, Sanders M, Dugger TC, Bianco R, Stricker T, Arteaga CL.

Clin Cancer Res. 2019 Feb 15;25(4):1433. doi: 10.1158/1078-0432.CCR-18-4268. No abstract available.

PMID:
30770492
6.

Correction: ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors.

Guerrero-Zotano AL, Stricker TP, Formisano L, Hutchinson KE, Stover DG, Lee KM, Schwarz LJ, Giltnane JM, Estrada MV, Jansen VM, Servetto A, Gavilá J, Perez-Fidalgo JA, Lluch A, Llombart-Cussac A, Bayar MA, Michiels S, André F, Arnedos M, Guillem V, Ruiz-Simon A, Arteaga CL.

Clin Cancer Res. 2019 Feb 15;25(4):1431. doi: 10.1158/1078-0432.CCR-18-4270. No abstract available.

7.

Correction: Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer.

Jansen VM, Bhola NE, Bauer JA, Formisano L, Lee KM, Hutchinson KE, Witkiewicz AK, Moore PD, Estrada MV, Sánchez V, Ericsson PG, Sanders ME, Pohlmann PR, Pishvaian MJ, Riddle DA, Dugger TC, Wei W, Knudsen ES, Arteaga CL.

Cancer Res. 2019 Feb 15;79(4):874. doi: 10.1158/0008-5472.CAN-18-4086. No abstract available.

PMID:
30770369
8.

CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer.

Zhao ZM, Yost SE, Hutchinson KE, Li SM, Yuan YC, Noorbakhsh J, Liu Z, Warden C, Johnson RM, Wu X, Chuang JH, Yuan Y.

BMC Cancer. 2019 Jan 21;19(1):96. doi: 10.1186/s12885-019-5290-4.

9.

The Effects of System Changes in Grazed Dairy Farmlet Trials on Greenhouse Gas Emissions.

van der Weerden T, Beukes P, de Klein C, Hutchinson K, Farrell L, Stormink T, Romera A, Dalley D, Monaghan R, Chapman D, Macdonald K, Dynes R.

Animals (Basel). 2018 Dec 7;8(12). pii: E234. doi: 10.3390/ani8120234.

10.

Development and pilot evaluation of a pregnancy-specific mobile health tool: a qualitative investigation of SmartMoms Canada.

Halili L, Liu R, Hutchinson KA, Semeniuk K, Redman LM, Adamo KB.

BMC Med Inform Decis Mak. 2018 Nov 12;18(1):95. doi: 10.1186/s12911-018-0705-8.

11.

Delayed access to emergency obstetrical care among preeclamptic and non-preeclamptic women in Port-Au-Prince, Haiti.

Hutchinson K, Bryant M, Bachman DeSilva M, Price D, Sabin L, Bryson L, Jean Charles R, Declercq E.

BMC Pregnancy Childbirth. 2018 Aug 20;18(1):337. doi: 10.1186/s12884-018-1961-4.

12.

Co-creation of a family-focused service model living with younger onset dementia.

Hutchinson K, Roberts C, Roach P, Kurrle S.

Dementia (London). 2018 Aug 15:1471301218793477. doi: 10.1177/1471301218793477. [Epub ahead of print]

PMID:
30111180
13.

Pneumatosis of the intestines, colon and liver in a young cat.

Hutchinson KM, Tart K, Anderson KL, Powell LL.

Vet Med Sci. 2018 May;4(2):150-158. doi: 10.1002/vms3.96. Epub 2018 Feb 28.

14.

Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.

Aleksic T, Gray N, Wu X, Rieunier G, Osher E, Mills J, Verrill C, Bryant RJ, Han C, Hutchinson K, Lambert AG, Kumar R, Hamdy FC, Weyer-Czernilofsky U, Sanderson MP, Bogenrieder T, Taylor S, Macaulay VM.

Cancer Res. 2018 Jul 1;78(13):3497-3509. doi: 10.1158/0008-5472.CAN-17-3498. Epub 2018 May 7.

15.

ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors.

Guerrero-Zotano AL, Stricker TP, Formisano L, Hutchinson KE, Stover DG, Lee KM, Schwarz LJ, Giltnane JM, Estrada MV, Jansen VM, Servetto A, Gavilá J, Perez-Fidalgo JA, Lluch A, Llombart-Cussac A, Bayar MA, Michiels S, André F, Arnedos M, Guillem V, Ruiz-Simon A, Arteaga CL.

Clin Cancer Res. 2018 Jun 1;24(11):2517-2529. doi: 10.1158/1078-0432.CCR-17-2904. Epub 2018 Mar 26. Erratum in: Clin Cancer Res. 2019 Feb 15;25(4):1431.

16.

A Dosimetric Comparison of Breast Radiotherapy Techniques to Treat Locoregional Lymph Nodes Including the Internal Mammary Chain.

Ranger A, Dunlop A, Hutchinson K, Convery H, Maclennan MK, Chantler H, Twyman N, Rose C, McQuaid D, Amos RA, Griffin C, deSouza NM, Donovan E, Harris E, Coles CE, Kirby A.

Clin Oncol (R Coll Radiol). 2018 Jun;30(6):346-353. doi: 10.1016/j.clon.2018.01.017. Epub 2018 Mar 2.

17.

Vitamin D receptor variants and uncontrolled asthma.

Hutchinson K, Kerley CP, Faul J, Greally P, Coghlan D, Louw M, Elnazir B, Rochev Y.

Eur Ann Allergy Clin Immunol. 2018 May;50(3):108-116. doi: 10.23822/EurAnnACI.1764-1489.46. Epub 2017 Nov 28.

18.

Urine Drug Screen Trends from 1998 through 2011 Among Emergency Department Patients Treated in a University Teaching Hospital.

Korneeva N, Cvek U, Leskova A, Hutchinson K, Callahan A, Patek G, Trutschl M, Kilgore PCSR, McGauly P, Goeders N, Arnold T.

Toxicol Commun. 2018;2(1):24-34. doi: 10.1080/24734306.2018.1468539. Epub 2018 May 16.

19.

An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression.

Schwarz LJ, Hutchinson KE, Rexer BN, Estrada MV, Gonzalez Ericsson PI, Sanders ME, Dugger TC, Formisano L, Guerrero-Zotano A, Red-Brewer M, Young CD, Lantto J, Pedersen MW, Kragh M, Horak ID, Arteaga CL.

J Natl Cancer Inst. 2017 Nov 1;109(11). doi: 10.1093/jnci/djx065.

20.

MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.

Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL.

Cell Metab. 2017 Oct 3;26(4):633-647.e7. doi: 10.1016/j.cmet.2017.09.009.

21.

What do children need to know about dementia? The perspectives of children and people with personal experience of dementia.

Baker JR, Jeon YH, Goodenough B, Low LF, Bryden C, Hutchinson K, Richards L.

Int Psychogeriatr. 2018 May;30(5):673-684. doi: 10.1017/S1041610217002022. Epub 2017 Oct 2.

PMID:
28965499
22.

Verification of Abbott 25-OH-vitamin D assay on the architect system.

Hutchinson K, Healy M, Crowley V, Louw M, Rochev Y.

Pract Lab Med. 2017 Jan 17;7:27-35. doi: 10.1016/j.plabm.2017.01.001. eCollection 2017 Apr.

23.

Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.

Giltnane JM, Hutchinson KE, Stricker TP, Formisano L, Young CD, Estrada MV, Nixon MJ, Du L, Sanchez V, Ericsson PG, Kuba MG, Sanders ME, Mu XJ, Van Allen EM, Wagle N, Mayer IA, Abramson V, Gόmez H, Rizzo M, Toy W, Chandarlapaty S, Mayer EL, Christiansen J, Murphy D, Fitzgerald K, Wang K, Ross JS, Miller VA, Stephens PJ, Yelensky R, Garraway L, Shyr Y, Meszoely I, Balko JM, Arteaga CL.

Sci Transl Med. 2017 Aug 9;9(402). pii: eaai7993. doi: 10.1126/scitranslmed.aai7993. Erratum in: Sci Transl Med. 2019 Feb 13;11(479):.

24.

Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER+ Breast Cancer.

Formisano L, Stauffer KM, Young CD, Bhola NE, Guerrero-Zotano AL, Jansen VM, Estrada MM, Hutchinson KE, Giltnane JM, Schwarz LJ, Lu Y, Balko JM, Deas O, Cairo S, Judde JG, Mayer IA, Sanders M, Dugger TC, Bianco R, Stricker T, Arteaga CL.

Clin Cancer Res. 2017 Oct 15;23(20):6138-6150. doi: 10.1158/1078-0432.CCR-17-1232. Epub 2017 Jul 27. Erratum in: Clin Cancer Res. 2019 Feb 15;25(4):1433.

25.

The Kids Insight into Dementia Survey (KIDS): development and preliminary psychometric properties.

Baker JR, Low LF, Goodenough B, Jeon YH, Tsang RSM, Bryden C, Hutchinson K.

Aging Ment Health. 2018 Aug;22(8):947-953. doi: 10.1080/13607863.2017.1320703. Epub 2017 May 8.

PMID:
28481643
26.

Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer.

Jansen VM, Bhola NE, Bauer JA, Formisano L, Lee KM, Hutchinson KE, Witkiewicz AK, Moore PD, Estrada MV, Sánchez V, Ericsson PG, Sanders ME, Pohlmann PR, Pishvaian MJ, Riddle DA, Dugger TC, Wei W, Knudsen ES, Arteaga CL.

Cancer Res. 2017 May 1;77(9):2488-2499. doi: 10.1158/0008-5472.CAN-16-2653. Epub 2017 Mar 1. Erratum in: Cancer Res. 2019 Feb 15;79(4):874.

27.

A Review of Central Venous Pressure and Its Reliability as a Hemodynamic Monitoring Tool in Veterinary Medicine.

Hutchinson KM, Shaw SP.

Top Companion Anim Med. 2016 Sep;31(3):109-121. doi: 10.1053/j.tcam.2016.08.009. Epub 2016 Aug 9. Review.

PMID:
27968811
28.

Viral oncoprotein antibodies as a marker for recurrence of Merkel cell carcinoma: A prospective validation study.

Paulson KG, Lewis CW, Redman MW, Simonson WT, Lisberg A, Ritter D, Morishima C, Hutchinson K, Mudgistratova L, Blom A, Iyer J, Moshiri AS, Tarabadkar ES, Carter JJ, Bhatia S, Kawasumi M, Galloway DA, Wener MH, Nghiem P.

Cancer. 2017 Apr 15;123(8):1464-1474. doi: 10.1002/cncr.30475. Epub 2016 Dec 7.

29.

Vitamin D Improves Selected Metabolic Parameters but Not Neuropsychological or Quality of Life Indices in OSA: A Pilot Study.

Kerley CP, Hutchinson K, Bramham J, McGowan A, Faul J, Cormican L.

J Clin Sleep Med. 2017 Jan 15;13(1):19-26. doi: 10.5664/jcsm.6378.

30.

The Association Between 25 Hydroxyvitamin D and Airway Obstruction in Asthma.

Hutchinson K, Kerley C, Cormican L, Rochev Y, Faul J.

Ir Med J. 2016 Mar 10;109(3):371.

PMID:
27685818
31.

Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model (TtnΔIAjxn).

Bull M, Methawasin M, Strom J, Nair P, Hutchinson K, Granzier H.

Circ Res. 2016 Sep 2;119(6):764-72. doi: 10.1161/CIRCRESAHA.116.308904. Epub 2016 Jul 28.

32.

Pre/post-closure assessment of groundwater pharmaceutical fate in a wastewater-facility-impacted stream reach.

Bradley PM, Barber LB, Clark JM, Duris JW, Foreman WT, Furlong ET, Givens CE, Hubbard LE, Hutchinson KJ, Journey CA, Keefe SH, Kolpin DW.

Sci Total Environ. 2016 Oct 15;568:916-925. doi: 10.1016/j.scitotenv.2016.06.104. Epub 2016 Jun 24.

PMID:
27350092
33.

Thalamic stroke in a young adult with severe psoriasis refractory to adalimumab.

Kadayakkara DK, Bennett S, Hutchinson K.

JAAD Case Rep. 2015 Aug 28;1(5):324-6. doi: 10.1016/j.jdcr.2015.07.009. eCollection 2015 Sep. No abstract available.

34.

Vitamin D3 for uncontrolled childhood asthma: A pilot study.

Kerley CP, Hutchinson K, Cormican L, Faul J, Greally P, Coghlan D, Elnazir B.

Pediatr Allergy Immunol. 2016 Jun;27(4):404-12. doi: 10.1111/pai.12547. Epub 2016 Mar 21.

PMID:
26845753
35.

Deep Brain Stimulation and Medication Management in Parkinson's Disease.

Hutchinson K, Wick JY.

Consult Pharm. 2016 Feb;31(2):73-84. doi: 10.4140/TCP.n.2016.73.

PMID:
26842685
36.

Benefit Finding in Maternal Caregivers of Pediatric Cancer Survivors: A Mixed Methods Approach.

Willard VW, Hostetter SA, Hutchinson KC, Bonner MJ, Hardy KK.

J Pediatr Oncol Nurs. 2016 Sep;33(5):353-60. doi: 10.1177/1043454215620119. Epub 2016 Jan 25.

PMID:
26811326
37.

An ID2-dependent mechanism for VHL inactivation in cancer.

Lee SB, Frattini V, Bansal M, Castano AM, Sherman D, Hutchinson K, Bruce JN, Califano A, Liu G, Cardozo T, Iavarone A, Lasorella A.

Nature. 2016 Jan 14;529(7585):172-7. doi: 10.1038/nature16475. Epub 2016 Jan 6.

38.

Empowerment of young people who have a parent living with dementia: a social model perspective.

Hutchinson K, Roberts C, Daly M, Bulsara C, Kurrle S.

Int Psychogeriatr. 2016 Apr;28(4):657-68. doi: 10.1017/S1041610215001714. Epub 2015 Nov 13.

PMID:
26563607
39.

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.

Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13573-8. doi: 10.1073/pnas.1508273112. Epub 2015 Oct 20.

40.

Serum Vitamin D Is Significantly Inversely Associated with Disease Severity in Caucasian Adults with Obstructive Sleep Apnea Syndrome.

Kerley CP, Hutchinson K, Bolger K, McGowan A, Faul J, Cormican L.

Sleep. 2016 Feb 1;39(2):293-300. doi: 10.5665/sleep.5430.

41.

ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma.

Hutchinson KE, Johnson DB, Johnson AS, Sanchez V, Kuba M, Lu P, Chen X, Kelley MC, Wang Q, Zhao Z, Kris M, Berger MF, Sosman JA, Pao W.

Oncotarget. 2015 Sep 8;6(26):22348-60.

42.

Clinically relevant genes and regulatory pathways associated with NRASQ61 mutations in melanoma through an integrative genomics approach.

Jiang W, Jia P, Hutchinson KE, Johnson DB, Sosman JA, Zhao Z.

Oncotarget. 2015 Feb 10;6(4):2496-508.

43.

Melanoma BRAF fusions--response.

Hutchinson KE, Ross JS, Stephens PJ, Miller VA, Sosman JA, Pao W.

Clin Cancer Res. 2014 Dec 15;20(24):6632. doi: 10.1158/1078-0432.CCR-14-1152. No abstract available.

44.

Optimizing the sequence of anti-EGFR-targeted therapy in EGFR-mutant lung cancer.

Meador CB, Jin H, de Stanchina E, Nebhan CA, Pirazzoli V, Wang L, Lu P, Vuong H, Hutchinson KE, Jia P, Chen X, Eisenberg R, Ladanyi M, Politi K, Zhao Z, Lovly CM, Cross DA, Pao W.

Mol Cancer Ther. 2015 Feb;14(2):542-52. doi: 10.1158/1535-7163.MCT-14-0723. Epub 2014 Dec 4.

45.

Endurance exercise accelerates myocardial tissue oxygenation recovery and reduces ischemia reperfusion injury in mice.

Li Y, Cai M, Cao L, Qin X, Zheng T, Xu X, Sandvick TM, Hutchinson K, Wold LE, Hu K, Sun Q, Thomas DP, Ren J, He G.

PLoS One. 2014 Dec 4;9(12):e114205. doi: 10.1371/journal.pone.0114205. eCollection 2014.

46.

Dendrites are dispensable for basic motoneuron function but essential for fine tuning of behavior.

Ryglewski S, Kadas D, Hutchinson K, Schuetzler N, Vonhoff F, Duch C.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):18049-54. doi: 10.1073/pnas.1416247111. Epub 2014 Dec 1.

47.

Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling.

Hutchinson KR, Saripalli C, Chung CS, Granzier H.

J Mol Cell Cardiol. 2015 Feb;79:104-14. doi: 10.1016/j.yjmcc.2014.10.020. Epub 2014 Nov 8.

48.

MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis.

Jia P, Wang Q, Chen Q, Hutchinson KE, Pao W, Zhao Z.

Genome Biol. 2014;15(10):489.

49.

Does speckle tracking really improve diagnosis and risk stratification in patients with HF with normal EF?

Pellicori P, Hutchinson K, Clark AL, Cleland JG.

J Am Coll Cardiol. 2014 Oct 7;64(14):1535. doi: 10.1016/j.jacc.2014.02.616. No abstract available.

50.

Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes.

Chmielecki J, Hutchinson KE, Frampton GM, Chalmers ZR, Johnson A, Shi C, Elvin J, Ali SM, Ross JS, Basturk O, Balasubramanian S, Lipson D, Yelensky R, Pao W, Miller VA, Klimstra DS, Stephens PJ.

Cancer Discov. 2014 Dec;4(12):1398-405. doi: 10.1158/2159-8290.CD-14-0617. Epub 2014 Sep 29. Erratum in: Cancer Discov. 2015 Mar;5(3):332.

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