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Items: 12


The relative resistance of children to sepsis mortality: from pathways to drug candidates.

Joachim RB, Altschuler GM, Hutchinson JN, Wong HR, Hide WA, Kobzik L.

Mol Syst Biol. 2018 May 17;14(5):e7998. doi: 10.15252/msb.20177998.


Empirical comparison of reduced representation bisulfite sequencing and Infinium BeadChip reproducibility and coverage of DNA methylation in humans.

Carmona JJ, Accomando WP Jr, Binder AM, Hutchinson JN, Pantano L, Izzi B, Just AC, Lin X, Schwartz J, Vokonas PS, Amr SS, Baccarelli AA, Michels KB.

NPJ Genom Med. 2017 Apr 19;2:13. doi: 10.1038/s41525-017-0012-9. eCollection 2017.


Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation.

Gerarduzzi C, Kumar RK, Trivedi P, Ajay AK, Iyer A, Boswell S, Hutchinson JN, Waikar SS, Vaidya VS.

JCI Insight. 2017 Apr 20;2(8). pii: 90299. doi: 10.1172/jci.insight.90299. [Epub ahead of print]


Phosphoproteomic profiling of mouse primary HSPCs reveals new regulators of HSPC mobilization.

Wang LD, Ficarro SB, Hutchinson JN, Csepanyi-Komi R, Nguyen PT, Wisniewski E, Sullivan J, Hofmann O, Ligeti E, Marto JA, Wagers AJ.

Blood. 2016 Sep 15;128(11):1465-74. doi: 10.1182/blood-2016-05-711424. Epub 2016 Jun 30.


(Epi)Genetic analyses of age-related macular degeneration: case-control and discordant twin studies.

Hutchinson JN, Fagerness J, Kirby A, Reynolds R, Zak A, Gimelbrant A, Plenge R, Daly M, Chess A, Seddon JM.

Hum Hered. 2014;78(2):59-72. doi: 10.1159/000362814. Epub 2014 Jul 12.


Allele-specific methylation occurs at genetic variants associated with complex disease.

Hutchinson JN, Raj T, Fagerness J, Stahl E, Viloria FT, Gimelbrant A, Seddon J, Daly M, Chess A, Plenge R.

PLoS One. 2014 Jun 9;9(6):e98464. doi: 10.1371/journal.pone.0098464. eCollection 2014.


An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles.

Clemson CM, Hutchinson JN, Sara SA, Ensminger AW, Fox AH, Chess A, Lawrence JB.

Mol Cell. 2009 Mar 27;33(6):717-26. doi: 10.1016/j.molcel.2009.01.026. Epub 2009 Feb 12.


Widespread monoallelic expression on human autosomes.

Gimelbrant A, Hutchinson JN, Thompson BR, Chess A.

Science. 2007 Nov 16;318(5853):1136-40.


A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains.

Hutchinson JN, Ensminger AW, Clemson CM, Lynch CR, Lawrence JB, Chess A.

BMC Genomics. 2007 Feb 1;8:39.


Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion.

Hutchinson JN, Jin J, Cardiff RD, Woodgett JR, Muller WJ.

Cancer Res. 2004 May 1;64(9):3171-8.


Transgenic mouse models of human breast cancer.

Hutchinson JN, Muller WJ.

Oncogene. 2000 Dec 11;19(53):6130-7. Review.


Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis.

Webster MA, Hutchinson JN, Rauh MJ, Muthuswamy SK, Anton M, Tortorice CG, Cardiff RD, Graham FL, Hassell JA, Muller WJ.

Mol Cell Biol. 1998 Apr;18(4):2344-59.

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