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Author response: An interdisciplinary response to contemporary concerns about brain death determination.

Lewis A, Bernat JL, Blosser S, Bonnie RJ, Epstein LG, Hutchins J, Kirschen MP, Rubin M, Russell JA, Sattin JA, Wijdicks EFM, Greer DM.

Neurology. 2018 Sep 11;91(11):536-538. doi: 10.1212/WNL.0000000000006154. No abstract available.


Complications in Pediatric Regional Anesthesia: An Analysis of More than 100,000 Blocks from the Pediatric Regional Anesthesia Network.

Walker BJ, Long JB, Sathyamoorthy M, Birstler J, Wolf C, Bosenberg AT, Flack SH, Krane EJ, Sethna NF, Suresh S, Taenzer AH, Polaner DM, Martin L, Anderson C, Sunder R, Adams T, Martin L, Pankovich M, Sawardekar A, Birmingham P, Marcelino R, Ramarmurthi RJ, Szmuk P, Ungar GK, Lozano S, Boretsky K, Jain R, Matuszczak M, Petersen TR, Dillow J, Power R, Nguyen K, Lee BH, Chan L, Pineda J, Hutchins J, Mendoza K, Spisak K, Shah A, DelPizzo K, Dong N, Yalamanchili V, Venable C, Williams CA, Chaudahari R, Ohkawa S, Usljebrka H, Bhalla T, Vanzillotta PP, Apiliogullari S, Franklin AD, Ando A, Pestieau SR, Wright C, Rosenbloom J, Anderson T; Pediatric Regional Anesthesia Network Investigators.

Anesthesiology. 2018 Oct;129(4):721-732. doi: 10.1097/ALN.0000000000002372.


The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.

Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van der Lelij P, Kreidl E, Hutchins JR, Axelsson-Ekker H, Ellenberg J, Hyman AA, Mechtler K, Peters JM.

EMBO J. 2018 Aug 1;37(15). pii: e97150. doi: 10.15252/embj.201797150. Epub 2018 Jun 21.


The Use of Eye-Movement Desensitization Reprocessing (EMDR) Therapy in Treating Post-traumatic Stress Disorder-A Systematic Narrative Review.

Wilson G, Farrell D, Barron I, Hutchins J, Whybrow D, Kiernan MD.

Front Psychol. 2018 Jun 6;9:923. doi: 10.3389/fpsyg.2018.00923. eCollection 2018. Review.


Thoracic paravertebral block versus thoracic epidural analgesia for post-operative pain control in open pancreatic surgery: A randomized controlled trial.

Hutchins JL, Grandelis AJ, Kaizer AM, Jensen EH.

J Clin Anesth. 2018 Aug;48:41-45. doi: 10.1016/j.jclinane.2018.04.013. Epub 2018 May 3.


Total spinal and brainstem anesthesia as complication of paravertebral ropivacaine administration.

Foster LA, Deutz CK, Hutchins JL, Allen JA.

Neurol Clin Pract. 2017 Oct;7(5):430-432. doi: 10.1212/CPJ.0000000000000355. No abstract available.


An interdisciplinary response to contemporary concerns about brain death determination.

Lewis A, Bernat JL, Blosser S, Bonnie RJ, Epstein LG, Hutchins J, Kirschen MP, Rubin M, Russell JA, Sattin JA, Wijdicks EFM, Greer DM.

Neurology. 2018 Feb 27;90(9):423-426. doi: 10.1212/WNL.0000000000005033. Epub 2018 Jan 31.


An evaluation of the analgesic effect of AnestaGel™ on mechanical allodynia in a rat model of postoperative incisional pain.

Hutchins J, Taylor W.

J Pain Res. 2017 Dec 13;10:2807-2813. doi: 10.2147/JPR.S146759. eCollection 2017.


Laparoscopic transdiaphragmatic chest surgery: Early experience.

Andrade RS, Diaz-Gutierrez I, Hutchins J, Kaizer A, Small J, Rao M.

J Thorac Cardiovasc Surg. 2018 Mar;155(3):1294-1299. doi: 10.1016/j.jtcvs.2017.10.127. Epub 2017 Nov 10.


An Open-Label Study of Sufentanil Sublingual Tablet 30 Mcg in Patients with Postoperative Pain.

Hutchins JL, Leiman D, Minkowitz HS, Jove M, DiDonato KP, Palmer PP.

Pain Med. 2018 Oct 1;19(10):2058-2068. doi: 10.1093/pm/pnx248.


Multimodal Analgesia in Breast Surgical Procedures: Technical and Pharmacological Considerations for Liposomal Bupivacaine Use.

Afonso AM, Newman MI, Seeley N, Hutchins J, Smith KL, Mena G, Selber JC, Saint-Cyr MH, Gadsden JC.

Plast Reconstr Surg Glob Open. 2017 Sep 15;5(9):e1480. doi: 10.1097/GOX.0000000000001480. eCollection 2017 Sep.


Continuous Paravertebral Infusions as an Effective Adjunct for Postoperative Pain Management in Living Liver Donors: A Retrospective Observational Study.

Mistry K, Hutchins J, Leiting J, Mangalick K, Pruett T, Chinnakotla S.

Transplant Proc. 2017 Mar;49(2):309-315. doi: 10.1016/j.transproceed.2016.11.045.


Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.

Kasikara C, Kumar S, Kimani S, Tsou WI, Geng K, Davra V, Sriram G, Devoe C, Nguyen KN, Antes A, Krantz A, Rymarczyk G, Wilczynski A, Empig C, Freimark B, Gray M, Schlunegger K, Hutchins J, Kotenko SV, Birge RB.

Mol Cancer Res. 2017 Jun;15(6):753-764. doi: 10.1158/1541-7786.MCR-16-0350. Epub 2017 Feb 9.


Enhanced Recovery Program and Length of Stay After Laparotomy on a Gynecologic Oncology Service: A Randomized Controlled Trial.

Dickson EL, Stockwell E, Geller MA, Vogel RI, Mullany SA, Ghebre R, Witherhoff BJ, Downs LS Jr, Carson LF, Teoh D, Glasgow M, Gerber M, Rivard C, Erickson BK, Hutchins J, Argenta PA.

Obstet Gynecol. 2017 Feb;129(2):355-362. doi: 10.1097/AOG.0000000000001838.


Genomic Database Searching.

Hutchins JR.

Methods Mol Biol. 2017;1525:225-269.


Ultrasound-Guided Paravertebral Catheter Versus Intercostal Blocks for Postoperative Pain Control in Video-Assisted Thoracoscopic Surgery: A Prospective Randomized Trial.

Hutchins J, Sanchez J, Andrade R, Podgaetz E, Wang Q, Sikka R.

J Cardiothorac Vasc Anesth. 2017 Apr;31(2):458-463. doi: 10.1053/j.jvca.2016.08.010. Epub 2016 Aug 10.


Type 2 diabetes in a 5-year-old and single center experience of type 2 diabetes in youth under 10.

Hutchins J, Barajas RA, Hale D, Escaname E, Lynch J.

Pediatr Diabetes. 2017 Nov;18(7):674-677. doi: 10.1111/pedi.12463. Epub 2016 Nov 3. Review.


Paravertebral Catheter Use for Postoperative Pain Control in Patients After Lung Transplant Surgery: A Prospective Observational Study.

Hutchins J, Apostolidou I, Shumway S, Kelly R, Wang Q, Foster C, Loor G.

J Cardiothorac Vasc Anesth. 2017 Feb;31(1):142-146. doi: 10.1053/j.jvca.2016.05.006. Epub 2016 May 4.


Implications of orbital hybridization on the electronic properties of doped quantum dots: the case of Cu:CdSe.

Wright JT, Forsythe K, Hutchins J, Meulenberg RW.

Nanoscale. 2016 Apr 28;8(17):9417-24. doi: 10.1039/c6nr00494f.


Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma.

Freimark BD, Gong J, Ye D, Gray MJ, Nguyen V, Yin S, Hatch MM, Hughes CC, Schroit AJ, Hutchins JT, Brekken RA, Huang X.

Cancer Immunol Res. 2016 Jun;4(6):531-40. doi: 10.1158/2326-6066.CIR-15-0250. Epub 2016 Apr 4.


Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer.

Birge RB, Boeltz S, Kumar S, Carlson J, Wanderley J, Calianese D, Barcinski M, Brekken RA, Huang X, Hutchins JT, Freimark B, Empig C, Mercer J, Schroit AJ, Schett G, Herrmann M.

Cell Death Differ. 2016 Jun;23(6):962-78. doi: 10.1038/cdd.2016.11. Epub 2016 Feb 26. Review.


Proteomic data on the nuclear interactome of human MCM9.

Hutchins JR, Traver S, Coulombe P, Peiffer I, Kitzmann M, Latreille D, Méchali M.

Data Brief. 2015 Dec 11;6:410-5. doi: 10.1016/j.dib.2015.11.055. eCollection 2016 Mar.


Postoperative pain control with paravertebral catheters after pediatric total pancreatectomy and islet autotransplantation: a retrospective cohort study.

Hutchins J, Castro C, Wang Q, Chinnakotla S.

Paediatr Anaesth. 2016 Mar;26(3):315-20. doi: 10.1111/pan.12840. Epub 2016 Jan 8.


Evolution of transversus abdominis plane infiltration techniques for postsurgical analgesia following abdominal surgeries.

Gadsden J, Ayad S, Gonzales JJ, Mehta J, Boublik J, Hutchins J.

Local Reg Anesth. 2015 Dec 10;8:113-7. doi: 10.2147/LRA.S96253. eCollection 2015.


Extracting order from heterogeneity: A report on the EpiGeneSys workshop "Single Cell Epigenetics" in Montpellier, June 11-12, 2015.

Korthout T, Emanuelli G, Hutchins JR.

Bioessays. 2016 Jan;38(1):4-7. doi: 10.1002/bies.201500160. Epub 2015 Nov 16. Review.


Access to transportation for Chittenden County Vermont older adults.

Hadley Strout E, Fox L, Castro A, Haroun P, Leavitt B, Ross C, Sayan M, Delaney T, Platzer A, Hutchins J, Carney JK.

Aging Clin Exp Res. 2016 Aug;28(4):769-74. doi: 10.1007/s40520-015-0476-3. Epub 2015 Nov 5.


Relative Prevalence of Grapevine Leafroll-Associated Virus Species in Wine Grape-Growing Regions of California.

Sharma AM, Baraff B, Hutchins JT, Wong MK, Blaisdell GK, Cooper ML, Daane KM, Almeida RP.

PLoS One. 2015 Nov 3;10(11):e0142120. doi: 10.1371/journal.pone.0142120. eCollection 2015.


MCM9 Is Required for Mammalian DNA Mismatch Repair.

Traver S, Coulombe P, Peiffer I, Hutchins JR, Kitzmann M, Latreille D, Méchali M.

Mol Cell. 2015 Sep 3;59(5):831-9. doi: 10.1016/j.molcel.2015.07.010. Epub 2015 Aug 20.


Ultrasound guided subcostal transversus abdominis plane (TAP) infiltration with liposomal bupivacaine for patients undergoing robotic assisted hysterectomy: A prospective randomized controlled study.

Hutchins J, Delaney D, Vogel RI, Ghebre RG, Downs LS Jr, Carson L, Mullany S, Teoh D, Geller MA.

Gynecol Oncol. 2015 Sep;138(3):609-13. doi: 10.1016/j.ygyno.2015.06.008. Epub 2015 Jun 6.


Ultrasound-guided subcostal transversus abdominis plane infiltration with liposomal bupivacaine for patients undergoing robotic-assisted hysterectomy: a retrospective study.

Hutchins J, Vogel RI, Ghebre R, McNally A, Downs LS Jr, Gryzmala E, Geller MA.

Int J Gynecol Cancer. 2015 Jun;25(5):937-41. doi: 10.1097/IGC.0000000000000429.


Percutaneous thoracic paravertebral block reduces refractory ventricular tachyarrhythmias after left ventricular assist device implantation.

Kamdar F, Hutchins J, Missov E.

J Heart Lung Transplant. 2015 Jun;34(6):866-7. doi: 10.1016/j.healun.2015.01.988. Epub 2015 Feb 7. No abstract available.


Thoracic paravertebral catheter placement for acute rib pain in a pregnant patient with cystic fibrosis.

Hutchins JL, Jacobs RA.

A A Case Rep. 2015 Feb 1;4(3):31-2. doi: 10.1213/XAA.0000000000000075.


Professionalism in court: The neurologist as expert witness.

Cheshire WP, Hutchins JC.

Neurol Clin Pract. 2014 Aug;4(4):335-341.


What's that gene (or protein)? Online resources for exploring functions of genes, transcripts, and proteins.

Hutchins JR.

Mol Biol Cell. 2014 Apr;25(8):1187-201. doi: 10.1091/mbc.E13-10-0602. Review.


Color schlieren imaging with a two-path, double knife edge system.

Chaloupka JL, Woods M 3rd, Aas J, Hutchins J, Thistle JD.

Opt Express. 2014 Apr 7;22(7):8041-6. doi: 10.1364/OE.22.008041.


Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2'-C-methyl-6-O-methyl guanosine nucleoside and L-Alanine ester phosphoramidates.

Bourdin C, McGuigan C, Brancale A, Chamberlain S, Vernachio J, Hutchins J, Gorovits E, Kolykhalov A, Muhammad J, Patti J, Henson G, Bleiman B, Bryant KD, Ganguly B, Hunley D, Obikhod A, Walters CR, Wang J, Ramamurty CV, Battina SK, Srivinas Rao C.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):2260-4. doi: 10.1016/j.bmcl.2012.12.004. Epub 2012 Dec 20.


Use of continuous positive airway pressure reduces airway reactivity in adults with asthma.

Busk M, Busk N, Puntenney P, Hutchins J, Yu Z, Gunst SJ, Tepper RS.

Eur Respir J. 2013 Feb;41(2):317-22. doi: 10.1183/09031936.00059712. Epub 2012 Jul 26.


Extrapleural catheters: an effective alternative for treating postoperative pain for thoracic surgical patients.

Hutchins J, Sikka R, Prielipp RC.

Semin Thorac Cardiovasc Surg. 2012 Spring;24(1):15-8. doi: 10.1053/j.semtcvs.2012.04.009.


American Academy of Neurology policy on pharmaceutical and device industry support.

Hutchins JC, Rydell CM, Griggs RC, Sagsveen M, Bernat JL; American Academy of Neurology Pharmaceutical and Device Industry Conflict of Interest Task Force.

Neurology. 2012 Mar 6;78(10):750-4. doi: 10.1212/WNL.0b013e318248e4ff.


Systematic phosphorylation analysis of human mitotic protein complexes.

Hegemann B, Hutchins JR, Hudecz O, Novatchkova M, Rameseder J, Sykora MM, Liu S, Mazanek M, Lénárt P, Hériché JK, Poser I, Kraut N, Hyman AA, Yaffe MB, Mechtler K, Peters JM.

Sci Signal. 2011 Nov 8;4(198):rs12. doi: 10.1126/scisignal.2001993.


Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents.

McGuigan C, Madela K, Aljarah M, Bourdin C, Arrica M, Barrett E, Jones S, Kolykhalov A, Bleiman B, Bryant KD, Ganguly B, Gorovits E, Henson G, Hunley D, Hutchins J, Muhammad J, Obikhod A, Patti J, Walters CR, Wang J, Vernachio J, Ramamurty CV, Battina SK, Chamberlain S.

J Med Chem. 2011 Dec 22;54(24):8632-45. doi: 10.1021/jm2011673. Epub 2011 Nov 16.


Dual pro-drugs of 2'-C-methyl guanosine monophosphate as potent and selective inhibitors of hepatitis C virus.

McGuigan C, Madela K, Aljarah M, Gilles A, Battina SK, Ramamurty CV, Srinivas Rao C, Vernachio J, Hutchins J, Hall A, Kolykhalov A, Henson G, Chamberlain S.

Bioorg Med Chem Lett. 2011 Oct 1;21(19):6007-12. doi: 10.1016/j.bmcl.2011.06.013. Epub 2011 Aug 17.


Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.

Alexander J, Lim D, Joughin BA, Hegemann B, Hutchins JR, Ehrenberger T, Ivins F, Sessa F, Hudecz O, Nigg EA, Fry AM, Musacchio A, Stukenberg PT, Mechtler K, Peters JM, Smerdon SJ, Yaffe MB.

Sci Signal. 2011 Jun 28;4(179):ra42. doi: 10.1126/scisignal.2001796.


Pharmacokinetics and safety of FV-100, a novel oral anti-herpes zoster nucleoside analogue, administered in single and multiple doses to healthy young adult and elderly adult volunteers.

Pentikis HS, Matson M, Atiee G, Boehlecke B, Hutchins JT, Patti JM, Henson GW, Morris A.

Antimicrob Agents Chemother. 2011 Jun;55(6):2847-54. doi: 10.1128/AAC.01446-10. Epub 2011 Mar 28.


INX-08189, a phosphoramidate prodrug of 6-O-methyl-2'-C-methyl guanosine, is a potent inhibitor of hepatitis C virus replication with excellent pharmacokinetic and pharmacodynamic properties.

Vernachio JH, Bleiman B, Bryant KD, Chamberlain S, Hunley D, Hutchins J, Ames B, Gorovits E, Ganguly B, Hall A, Kolykhalov A, Liu Y, Muhammad J, Raja N, Walters CR, Wang J, Williams K, Patti JM, Henson G, Madela K, Aljarah M, Gilles A, McGuigan C.

Antimicrob Agents Chemother. 2011 May;55(5):1843-51. doi: 10.1128/AAC.01335-10. Epub 2011 Feb 28.


Upholding professionalism: the disciplinary process of the American Academy of Neurology.

Hutchins JC, Sagsveen MG, Larriviere D.

Neurology. 2010 Dec 14;75(24):2198-203. doi: 10.1212/WNL.0b013e318202014e. Epub 2010 Nov 17.


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