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Items: 1 to 50 of 89

1.

Comparative Bioavailability Study of a New Orodispersible Formulation of Ibuprofen Versus Two Existing Oral Tablet Formulations in Healthy Male and Female Volunteers.

Sugár D, Francombe D, da Silva T, Hanid S, Hutchings S.

Clin Ther. 2019 Jun 12. pii: S0149-2918(19)30243-7. doi: 10.1016/j.clinthera.2019.04.040. [Epub ahead of print]

PMID:
31202508
2.

Bioequivalence of 2 Naproxen Sodium Tablet Formulations in Healthy Male and Female Volunteers.

Sugár D, Francombe D, da Silva T, Adams R, Hutchings S.

Curr Ther Res Clin Exp. 2019 Jan 18;90:33-38. doi: 10.1016/j.curtheres.2019.01.004. eCollection 2019.

3.

The acceptability of fluoride varnish and fissure sealant treatments in children aged 6-9 delivered in a school setting.

Morgan-Trimmer S, Chadwick BL, Hutchings S, Scoble C, Lisles C, Drew CJ, Murphy S, Pickles T, Hood K, Chestnutt IG.

Community Dent Health. 2019 Feb 25;36(1):33-38. doi: 10.1922/CDH_4263Morgan-Trimmer06.

PMID:
30667189
4.

Incorporation of bioactive dairy hydrolysate influences the stability and digestion behaviour of milk protein stabilised emulsions.

McIntyre I, Carolan A, O'Sullivan M, Jacquier JC, Hutchings S, Murray B, O'Riordan D.

Food Funct. 2018 Nov 14;9(11):5813-5823. doi: 10.1039/c8fo00912k.

PMID:
30352110
5.

Cancers in France in 2015 attributable to occupational exposures.

Marant Micallef C, Shield KD, Vignat J, Baldi I, Charbotel B, Fervers B, Gilg Soit Ilg A, Guénel P, Olsson A, Rushton L, Hutchings SJ, Cléro E, Laurier D, Scanff P, Bray F, Straif K, Soerjomataram I.

Int J Hyg Environ Health. 2019 Jan;222(1):22-29. doi: 10.1016/j.ijheh.2018.07.015. Epub 2018 Aug 30.

PMID:
30174219
6.

Novel techniques to understand consumer responses towards food products: A review with a focus on meat.

Torrico DD, Hutchings SC, Ha M, Bittner EP, Fuentes S, Warner RD, Dunshea FR.

Meat Sci. 2018 Oct;144:30-42. doi: 10.1016/j.meatsci.2018.06.006. Epub 2018 Jun 8. Review.

PMID:
30008336
7.

Microcirculatory Impairment Is Associated With Multiple Organ Dysfunction Following Traumatic Hemorrhagic Shock: The MICROSHOCK Study.

Hutchings SD, Naumann DN, Hopkins P, Mellis C, Riozzi P, Sartini S, Mamuza J, Harris T, Midwinter MJ, Wendon J.

Crit Care Med. 2018 Sep;46(9):e889-e896. doi: 10.1097/CCM.0000000000003275.

PMID:
29957708
8.

Impact of plasma viscosity on microcirculatory flow after traumatic haemorrhagic shock: A prospective observational study.

Naumann DN, Hazeldine J, Bishop J, Midwinter MJ, Harrison P, Nash G, Hutchings SD.

Clin Hemorheol Microcirc. 2019;71(1):71-82. doi: 10.3233/CH-180397.

PMID:
29843227
9.

Occupational exposures and cancer: a review of agents and relative risk estimates.

Marant Micallef C, Shield KD, Baldi I, Charbotel B, Fervers B, Gilg Soit Ilg A, Guénel P, Olsson A, Rushton L, Hutchings SJ, Straif K, Soerjomataram I.

Occup Environ Med. 2018 Aug;75(8):604-614. doi: 10.1136/oemed-2017-104858. Epub 2018 May 7.

PMID:
29735747
10.

Predicting rapid analgesic onset of ibuprofen salts compared with ibuprofen acid: Tlag, Tlow, Tmed, and a novel parameter, TCmaxRef.

Miles L, Hall J, Jenner B, Addis R, Hutchings S.

Curr Med Res Opin. 2018 Aug;34(8):1483-1490. doi: 10.1080/03007995.2018.1466697. Epub 2018 Apr 27.

PMID:
29667449
11.

Sugar reduction without compromising sensory perception. An impossible dream?

Hutchings SC, Low JYQ, Keast RSJ.

Crit Rev Food Sci Nutr. 2018 Mar 21:1-21. doi: 10.1080/10408398.2018.1450214. [Epub ahead of print]

PMID:
29561168
12.

Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine.

Ince C, Boerma EC, Cecconi M, De Backer D, Shapiro NI, Duranteau J, Pinsky MR, Artigas A, Teboul JL, Reiss IKM, Aldecoa C, Hutchings SD, Donati A, Maggiorini M, Taccone FS, Hernandez G, Payen D, Tibboel D, Martin DS, Zarbock A, Monnet X, Dubin A, Bakker J, Vincent JL, Scheeren TWL; Cardiovascular Dynamics Section of the ESICM.

Intensive Care Med. 2018 Mar;44(3):281-299. doi: 10.1007/s00134-018-5070-7. Epub 2018 Feb 6.

PMID:
29411044
13.

Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study.

Naumann DN, Hazeldine J, Dinsdale RJ, Bishop JR, Midwinter MJ, Harrison P, Hutchings SD, Lord JM.

PLoS One. 2017 Dec 19;12(12):e0189870. doi: 10.1371/journal.pone.0189870. eCollection 2017.

14.

Evaluating the feasibility of conducting a trial using a patient decision aid in implantable cardioverter defibrillator candidates: a randomized controlled feasibility trial.

Carroll SL, Stacey D, McGillion M, Healey JS, Foster G, Hutchings S, Arthur HM, Browne G, Thabane L.

Pilot Feasibility Stud. 2017 Nov 21;3:49. doi: 10.1186/s40814-017-0189-9. eCollection 2017.

15.

Poor microcirculatory flow dynamics are associated with endothelial cell damage and glycocalyx shedding after traumatic hemorrhagic shock.

Naumann DN, Hazeldine J, Midwinter MJ, Hutchings SD, Harrison P.

J Trauma Acute Care Surg. 2018 Jan;84(1):81-88. doi: 10.1097/TA.0000000000001695.

PMID:
28885470
16.

Comparison of the Systemic and Local Pharmacokinetics of Clonidine Mucoadhesive Buccal Tablets with Reference Clonidine Oral Tablets in Healthy Volunteers: An Open-Label Randomised Cross-Over Trial.

Vasseur B, Dufour A, Houdas L, Goodwin H, Harries K, Emul NY, Hutchings S.

Adv Ther. 2017 Aug;34(8):2022-2032. doi: 10.1007/s12325-017-0585-9. Epub 2017 Jul 19.

PMID:
28726169
17.

Mechanism of resistance to mesotrione in an Amaranthus tuberculatus population from Nebraska, USA.

Kaundun SS, Hutchings SJ, Dale RP, Howell A, Morris JA, Kramer VC, Shivrain VK, Mcindoe E.

PLoS One. 2017 Jun 29;12(6):e0180095. doi: 10.1371/journal.pone.0180095. eCollection 2017.

18.

Seal or Varnish? A randomised controlled trial to determine the relative cost and effectiveness of pit and fissure sealant and fluoride varnish in preventing dental decay.

Chestnutt IG, Hutchings S, Playle R, Morgan-Trimmer S, Fitzsimmons D, Aawar N, Angel L, Derrick S, Drew C, Hoddell C, Hood K, Humphreys I, Kirby N, Lau TMM, Lisles C, Morgan MZ, Murphy S, Nuttall J, Onishchenko K, Phillips C, Pickles T, Scoble C, Townson J, Withers B, Chadwick BL.

Health Technol Assess. 2017 Apr;21(21):1-256. doi: 10.3310/hta21210.

19.

Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment.

Cherrie JW, Hutchings S, Gorman Ng M, Mistry R, Corden C, Lamb J, Sánchez Jiménez A, Shafrir A, Sobey M, van Tongeren M, Rushton L.

Br J Cancer. 2017 Jul 11;117(2):274-281. doi: 10.1038/bjc.2017.161. Epub 2017 Jun 13.

20.

Estimating the burden of occupational cancer: assessing bias and uncertainty.

Hutchings S, Rushton L.

Occup Environ Med. 2017 Aug;74(8):604-611. doi: 10.1136/oemed-2016-103810. Epub 2017 Apr 17.

21.

Fissure Seal or Fluoride Varnish? A Randomized Trial of Relative Effectiveness.

Chestnutt IG, Playle R, Hutchings S, Morgan-Trimmer S, Fitzsimmons D, Aawar N, Angel L, Derrick S, Drew C, Hoddell C, Hood K, Humphreys I, Kirby N, Lau TMM, Lisles C, Morgan MZ, Murphy S, Nuttall J, Onishchenko K, Phillips C, Pickles T, Scoble C, Townson J, Withers B, Chadwick BL.

J Dent Res. 2017 Jul;96(7):754-761. doi: 10.1177/0022034517702094. Epub 2017 Apr 10. Review.

PMID:
28394709
22.
23.

The future excess fraction of occupational cancer among those exposed to carcinogens at work in Australia in 2012.

Carey RN, Hutchings SJ, Rushton L, Driscoll TR, Reid A, Glass DC, Darcey E, Si S, Peters S, Benke G, Fritschi L.

Cancer Epidemiol. 2017 Apr;47:1-6. doi: 10.1016/j.canep.2016.12.009. Epub 2017 Jan 9.

PMID:
28081474
24.

Safety and feasibility of sublingual microcirculation assessment in the emergency department for civilian and military patients with traumatic haemorrhagic shock: a prospective cohort study.

Naumann DN, Mellis C, Smith IM, Mamuza J, Skene I, Harris T, Midwinter MJ, Hutchings SD.

BMJ Open. 2016 Dec 21;6(12):e014162. doi: 10.1136/bmjopen-2016-014162.

25.

Modification of aftertaste with a menthol mouthwash reduces food wanting, liking, and ad libitum intake of potato crisps.

Hutchings SC, Horner KM, Dible VA, Grigor JMV, O'Riordan D.

Appetite. 2017 Jan 1;108:57-67. doi: 10.1016/j.appet.2016.09.022. Epub 2016 Sep 20.

PMID:
27663531
26.

Real-time point of care microcirculatory assessment of shock: design, rationale and application of the point of care microcirculation (POEM) tool.

Naumann DN, Mellis C, Husheer SL, Hopkins P, Bishop J, Midwinter MJ, Hutchings SD.

Crit Care. 2016 Sep 30;20(1):310.

27.

Molecular and Cellular Responses to Interleukin-4 Treatment in a Rat Model of Transient Ischemia.

Lively S, Hutchings S, Schlichter LC.

J Neuropathol Exp Neurol. 2016 Sep 15. pii: nlw081. [Epub ahead of print]

28.

Searching For the Optimal Fluid to Restore Microcirculatory Flow Dynamics After Haemorrhagic Shock: A Systematic Review of Preclinical Studies.

Naumann DN, Beaven A, Dretzke J, Hutchings S, Midwinter MJ.

Shock. 2016 Dec;46(6):609-622. Review.

PMID:
27465755
29.

Microcirculatory perfusion shows wide inter-individual variation and is important in determining shock reversal during resuscitation in a porcine experimental model of complex traumatic hemorrhagic shock.

Hutchings SD, Naumann DN, Watts S, Wilson C, Burton C, Wendon J, Kirkman E.

Intensive Care Med Exp. 2016 Dec;4(1):17. doi: 10.1186/s40635-016-0088-z. Epub 2016 Jun 24.

30.

The future excess fraction model for calculating burden of disease.

Fritschi L, Chan J, Hutchings SJ, Driscoll TR, Wong AY, Carey RN.

BMC Public Health. 2016 May 11;16:386. doi: 10.1186/s12889-016-3066-1.

31.

Occupations associated with COPD risk in the large population-based UK Biobank cohort study.

De Matteis S, Jarvis D, Hutchings S, Darnton A, Fishwick D, Sadhra S, Rushton L, Cullinan P.

Occup Environ Med. 2016 Jun;73(6):378-84. doi: 10.1136/oemed-2015-103406. Epub 2016 Mar 21.

32.

Observational study of the effects of traumatic injury, haemorrhagic shock and resuscitation on the microcirculation: a protocol for the MICROSHOCK study.

Hutchings S, Naumann DN, Harris T, Wendon J, Midwinter MJ.

BMJ Open. 2016 Mar 4;6(3):e010893. doi: 10.1136/bmjopen-2015-010893.

33.

A change in the trend in dosulepin usage following the introduction of a prescribing indicator but not after two national safety warnings.

Deslandes PN, Jenkins KS, Haines KE, Hutchings S, Cannings-John R, Lewis TL, Bracchi RC, Routledge PA.

J Clin Pharm Ther. 2016 Apr;41(2):224-8. doi: 10.1111/jcpt.12376. Epub 2016 Mar 2.

PMID:
26936206
34.

Venous-to-arterial CO2 differences and the quest for bedside point-of-care monitoring to assess the microcirculation during shock.

Naumann DN, Midwinter MJ, Hutchings S.

Ann Transl Med. 2016 Jan;4(2):37. doi: 10.3978/j.issn.2305-5839.2015.12.61.

35.

Nurse-delivered focused echocardiography to determine intravascular volume status in a deployed maritime critical care unit.

Hutchings S, Bisset L, Cantillon L, Keating-Brown P, Jeffreys S, Muzvidziwa C, Richmond E, Rees P.

J R Nav Med Serv. 2015;101(2):124-8.

PMID:
26867411
36.

The Cytocam video microscope. A new method for visualising the microcirculation using Incident Dark Field technology.

Hutchings S, Watts S, Kirkman E.

Clin Hemorheol Microcirc. 2016;62(3):261-71. doi: 10.3233/CH-152013.

PMID:
26484715
37.

Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models.

Naumann DN, Dretzke J, Hutchings S, Midwinter MJ.

Syst Rev. 2015 Oct 5;4:135. doi: 10.1186/s13643-015-0113-4.

39.

Development of the New Zealand strategy for local eradication of tuberculosis from wildlife and livestock.

Livingstone PG, Hancox N, Nugent G, Mackereth G, Hutchings SA.

N Z Vet J. 2015 Jun;63 Suppl 1:98-107. doi: 10.1080/00480169.2015.1013581. Epub 2015 Apr 2. Review.

40.

The proportion of cancer attributable to occupational exposures.

Purdue MP, Hutchings SJ, Rushton L, Silverman DT.

Ann Epidemiol. 2015 Mar;25(3):188-92. doi: 10.1016/j.annepidem.2014.11.009. Epub 2014 Nov 13. Review.

41.

Epidemiology, diagnostics, and management of tuberculosis in domestic cattle and deer in New Zealand in the face of a wildlife reservoir.

Buddle BM, de Lisle GW, Griffin JF, Hutchings SA.

N Z Vet J. 2015 Jun;63 Suppl 1:19-27. doi: 10.1080/00480169.2014.929518. Epub 2015 Feb 3. Review.

42.

Deployed research.

Nordmann G, Woolley T, Doughty H, Dalle Lucca J, Hutchings S, Kirkman E.

J R Army Med Corps. 2014 Jun;160(2):92-8. doi: 10.1136/jramc-2014-000272. Epub 2014 Apr 30.

PMID:
24786340
43.

Conducting clinical research in the deployed intensive care unit: challenges and solutions.

Hutchings SD, Howarth G, Rees P, Midwinter M.

J R Nav Med Serv. 2013;99(3):151-3.

PMID:
24511805
44.

The cytokine and endocannabinoid systems are co-regulated by NF-κB p65/RelA in cell culture and transgenic mouse models of Huntington's disease and in striatal tissue from Huntington's disease patients.

Laprairie RB, Warford JR, Hutchings S, Robertson GS, Kelly ME, Denovan-Wright EM.

J Neuroimmunol. 2014 Feb 15;267(1-2):61-72. doi: 10.1016/j.jneuroim.2013.12.008. Epub 2013 Dec 12.

PMID:
24360910
45.

A strategic approach to eradication of bovine TB from wildlife in New Zealand.

Hutchings SA, Hancox N, Livingstone PG.

Transbound Emerg Dis. 2013 Nov;60 Suppl 1:85-91. doi: 10.1111/tbed.12079.

PMID:
24171853
46.

Role of a novel I1781T mutation and other mechanisms in conferring resistance to acetyl-CoA carboxylase inhibiting herbicides in a black-grass population.

Kaundun SS, Hutchings SJ, Dale RP, McIndoe E.

PLoS One. 2013 Jul 25;8(7):e69568. doi: 10.1371/journal.pone.0069568. Print 2013.

47.

UK health performance: findings of the Global Burden of Disease Study 2010.

Murray CJ, Richards MA, Newton JN, Fenton KA, Anderson HR, Atkinson C, Bennett D, Bernabé E, Blencowe H, Bourne R, Braithwaite T, Brayne C, Bruce NG, Brugha TS, Burney P, Dherani M, Dolk H, Edmond K, Ezzati M, Flaxman AD, Fleming TD, Freedman G, Gunnell D, Hay RJ, Hutchings SJ, Ohno SL, Lozano R, Lyons RA, Marcenes W, Naghavi M, Newton CR, Pearce N, Pope D, Rushton L, Salomon JA, Shibuya K, Vos T, Wang H, Williams HC, Woolf AD, Lopez AD, Davis A.

Lancet. 2013 Mar 23;381(9871):997-1020. doi: 10.1016/S0140-6736(13)60355-4. Epub 2013 Mar 5.

PMID:
23668584
48.

Key role for a glutathione transferase in multiple-herbicide resistance in grass weeds.

Cummins I, Wortley DJ, Sabbadin F, He Z, Coxon CR, Straker HE, Sellars JD, Knight K, Edwards L, Hughes D, Kaundun SS, Hutchings SJ, Steel PG, Edwards R.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5812-7. doi: 10.1073/pnas.1221179110. Epub 2013 Mar 25.

49.

A novel W1999S mutation and non-target site resistance impact on acetyl-CoA carboxylase inhibiting herbicides to varying degrees in a UK Lolium multiflorum population.

Kaundun SS, Bailly GC, Dale RP, Hutchings SJ, McIndoe E.

PLoS One. 2013;8(2):e58012. doi: 10.1371/journal.pone.0058012. Epub 2013 Feb 28.

50.

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, Amann M, Anderson HR, Andrews KG, Aryee M, Atkinson C, Bacchus LJ, Bahalim AN, Balakrishnan K, Balmes J, Barker-Collo S, Baxter A, Bell ML, Blore JD, Blyth F, Bonner C, Borges G, Bourne R, Boussinesq M, Brauer M, Brooks P, Bruce NG, Brunekreef B, Bryan-Hancock C, Bucello C, Buchbinder R, Bull F, Burnett RT, Byers TE, Calabria B, Carapetis J, Carnahan E, Chafe Z, Charlson F, Chen H, Chen JS, Cheng AT, Child JC, Cohen A, Colson KE, Cowie BC, Darby S, Darling S, Davis A, Degenhardt L, Dentener F, Des Jarlais DC, Devries K, Dherani M, Ding EL, Dorsey ER, Driscoll T, Edmond K, Ali SE, Engell RE, Erwin PJ, Fahimi S, Falder G, Farzadfar F, Ferrari A, Finucane MM, Flaxman S, Fowkes FG, Freedman G, Freeman MK, Gakidou E, Ghosh S, Giovannucci E, Gmel G, Graham K, Grainger R, Grant B, Gunnell D, Gutierrez HR, Hall W, Hoek HW, Hogan A, Hosgood HD 3rd, Hoy D, Hu H, Hubbell BJ, Hutchings SJ, Ibeanusi SE, Jacklyn GL, Jasrasaria R, Jonas JB, Kan H, Kanis JA, Kassebaum N, Kawakami N, Khang YH, Khatibzadeh S, Khoo JP, Kok C, Laden F, Lalloo R, Lan Q, Lathlean T, Leasher JL, Leigh J, Li Y, Lin JK, Lipshultz SE, London S, Lozano R, Lu Y, Mak J, Malekzadeh R, Mallinger L, Marcenes W, March L, Marks R, Martin R, McGale P, McGrath J, Mehta S, Mensah GA, Merriman TR, Micha R, Michaud C, Mishra V, Mohd Hanafiah K, Mokdad AA, Morawska L, Mozaffarian D, Murphy T, Naghavi M, Neal B, Nelson PK, Nolla JM, Norman R, Olives C, Omer SB, Orchard J, Osborne R, Ostro B, Page A, Pandey KD, Parry CD, Passmore E, Patra J, Pearce N, Pelizzari PM, Petzold M, Phillips MR, Pope D, Pope CA 3rd, Powles J, Rao M, Razavi H, Rehfuess EA, Rehm JT, Ritz B, Rivara FP, Roberts T, Robinson C, Rodriguez-Portales JA, Romieu I, Room R, Rosenfeld LC, Roy A, Rushton L, Salomon JA, Sampson U, Sanchez-Riera L, Sanman E, Sapkota A, Seedat S, Shi P, Shield K, Shivakoti R, Singh GM, Sleet DA, Smith E, Smith KR, Stapelberg NJ, Steenland K, Stöckl H, Stovner LJ, Straif K, Straney L, Thurston GD, Tran JH, Van Dingenen R, van Donkelaar A, Veerman JL, Vijayakumar L, Weintraub R, Weissman MM, White RA, Whiteford H, Wiersma ST, Wilkinson JD, Williams HC, Williams W, Wilson N, Woolf AD, Yip P, Zielinski JM, Lopez AD, Murray CJ, Ezzati M, AlMazroa MA, Memish ZA.

Lancet. 2012 Dec 15;380(9859):2224-60. doi: 10.1016/S0140-6736(12)61766-8. Erratum in: Lancet. 2013 Feb 23;381(9867):628. AlMazroa, Mohammad A [added]; Memish, Ziad A [added]. Erratum in: Lancet. 2013 Apr 13;381(9874):1276.

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