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Items: 19

1.

Fragments of SLIT3 inhibit cellular migration.

Schubert T, Denk AE, Ruedel A, Kaufmann S, Hustert E, Bastone P, Bosserhoff AK.

Int J Mol Med. 2012 Nov;30(5):1133-7. doi: 10.3892/ijmm.2012.1098. Epub 2012 Aug 20.

PMID:
22922792
2.

GDF-5 and BMP-2 regulate bone cell differentiation by gene expression of MSX1, MSX2, Dlx5, and Runx2 and influence OCN gene expression in vitro.

Koch FP, Weinbach C, Hustert E, Al-Nawas B, Wagner W.

Int J Periodontics Restorative Dent. 2012 Jun;32(3):285-93.

PMID:
22408773
3.

Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.

Skuntz S, Mankoo B, Nguyen MT, Hustert E, Nakayama A, Tournier-Lasserve E, Wright CV, Pachnis V, Bharti K, Arnheiter H.

Dev Biol. 2009 Aug 15;332(2):383-95. doi: 10.1016/j.ydbio.2009.06.006. Epub 2009 Jun 9.

4.

A natural variant of the heme-binding signature (R441C) resulting in complete loss of function of CYP2D6.

Klein K, Tatzel S, Raimundo S, Saussele T, Hustert E, Pleiss J, Eichelbaum M, Zanger UM.

Drug Metab Dispos. 2007 Aug;35(8):1247-50. Epub 2007 Apr 25.

PMID:
17460029
5.

Increased levels of aflatoxin-albumin adducts are associated with CYP3A5 polymorphisms in The Gambia, West Africa.

Wojnowski L, Turner PC, Pedersen B, Hustert E, Brockmöller J, Mendy M, Whittle HC, Kirk G, Wild CP.

Pharmacogenetics. 2004 Oct;14(10):691-700.

PMID:
15454734
6.

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).

Burk O, Koch I, Raucy J, Hustert E, Eichelbaum M, Brockmöller J, Zanger UM, Wojnowski L.

J Biol Chem. 2004 Sep 10;279(37):38379-85. Epub 2004 Jul 12.

7.

Pharmacokinetics of midazolam in CYP3A4- and CYP3A5-genotyped subjects.

Eap CB, Buclin T, Hustert E, Bleiber G, Golay KP, Aubert AC, Baumann P, Telenti A, Kerb R.

Eur J Clin Pharmacol. 2004 Jun;60(4):231-6. Epub 2004 Apr 28.

PMID:
15114431
8.

Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity.

Eap CB, Buclin T, Cucchia G, Zullino D, Hustert E, Bleiber G, Golay KP, Aubert AC, Baumann P, Telenti A, Kerb R.

Eur J Clin Pharmacol. 2004 Jun;60(4):237-46. Epub 2004 Apr 28.

PMID:
15114429
9.

Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA.

Koch I, Weil R, Wolbold R, Brockmöller J, Hustert E, Burk O, Nuessler A, Neuhaus P, Eichelbaum M, Zanger U, Wojnowski L.

Drug Metab Dispos. 2002 Oct;30(10):1108-14.

PMID:
12228187
10.

Re: modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

Wojnowski L, Hustert E, Klein K, Goldammer M, Haberl M, Kirchheiner J, Koch I, Klattig J, Zanger U, Brockmöller J.

J Natl Cancer Inst. 2002 Apr 17;94(8):630-1; author reply 631-2. No abstract available.

PMID:
11959896
11.

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L.

J Biol Chem. 2002 Jul 5;277(27):24280-8. Epub 2002 Apr 8.

12.

The genetic determinants of the CYP3A5 polymorphism.

Hustert E, Haberl M, Burk O, Wolbold R, He YQ, Klein K, Nuessler AC, Neuhaus P, Klattig J, Eiselt R, Koch I, Zibat A, Brockmöller J, Halpert JR, Zanger UM, Wojnowski L.

Pharmacogenetics. 2001 Dec;11(9):773-9.

PMID:
11740341
13.

Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4.

Hustert E, Zibat A, Presecan-Siedel E, Eiselt R, Mueller R, Fuss C, Brehm I, Brinkmann U, Eichelbaum M, Wojnowski L, Burk O.

Drug Metab Dispos. 2001 Nov;29(11):1454-9.

PMID:
11602521
14.

Identification and functional characterization of eight CYP3A4 protein variants.

Eiselt R, Domanski TL, Zibat A, Mueller R, Presecan-Siedel E, Hustert E, Zanger UM, Brockmoller J, Klenk HP, Meyer UA, Khan KK, He YA, Halpert JR, Wojnowski L.

Pharmacogenetics. 2001 Jul;11(5):447-58.

PMID:
11470997
15.

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.

Gellner K, Eiselt R, Hustert E, Arnold H, Koch I, Haberl M, Deglmann CJ, Burk O, Buntefuss D, Escher S, Bishop C, Koebe HG, Brinkmann U, Klenk HP, Kleine K, Meyer UA, Wojnowski L.

Pharmacogenetics. 2001 Mar;11(2):111-21.

PMID:
11266076
16.

A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression.

Faiella A, Wernig M, Consalez GG, Hostick U, Hofmann C, Hustert E, Boncinelli E, Balling R, Nadeau JH.

Hum Mol Genet. 2000 Jan 22;9(2):227-36.

PMID:
10607833
17.

The SOX10/Sox10 gene from human and mouse: sequence, expression, and transactivation by the encoded HMG domain transcription factor.

Pusch C, Hustert E, Pfeifer D, Südbeck P, Kist R, Roe B, Wang Z, Balling R, Blin N, Scherer G.

Hum Genet. 1998 Aug;103(2):115-23.

PMID:
9760192
19.

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9.

Wagner T, Wirth J, Meyer J, Zabel B, Held M, Zimmer J, Pasantes J, Bricarelli FD, Keutel J, Hustert E, Wolf U, Tommerup N, Schempp W, Scherer G.

Cell. 1994 Dec 16;79(6):1111-20.

PMID:
8001137

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