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Items: 1 to 50 of 212

1.

Shiga toxin binding alters lipid packing and the domain structure of Gb3-containing membranes: a solid-state NMR study.

Bosse M, Sibold J, Scheidt HA, Patalag LJ, Kettelhoit K, Ries A, Werz DB, Steinem C, Huster D.

Phys Chem Chem Phys. 2019 Jul 17;21(28):15630-15638. doi: 10.1039/c9cp02501d.

PMID:
31268447
2.

NMR and Molecular Modeling Reveal Specificity of the Interactions between CXCL14 and Glycosaminoglycans.

Penk A, Baumann L, Huster D, Samsonov SA.

Glycobiology. 2019 Jul 2. pii: cwz047. doi: 10.1093/glycob/cwz047. [Epub ahead of print]

PMID:
31264681
3.

Thermophoretic trap for single amyloid fibril and protein aggregation studies.

Fränzl M, Thalheim T, Adler J, Huster D, Posseckardt J, Mertig M, Cichos F.

Nat Methods. 2019 Jul;16(7):611-614. doi: 10.1038/s41592-019-0451-6. Epub 2019 Jun 24.

PMID:
31235884
4.

Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase Cleavage.

Götz A, Mylonas N, Högel P, Silber M, Heinel H, Menig S, Vogel A, Feyrer H, Huster D, Luy B, Langosch D, Scharnagl C, Muhle-Goll C, Kamp F, Steiner H.

Biophys J. 2019 Jun 4;116(11):2103-2120. doi: 10.1016/j.bpj.2019.04.030. Epub 2019 May 3.

PMID:
31130234
5.

Structural Model of Ghrelin Bound to its G Protein-Coupled Receptor.

Bender BJ, Vortmeier G, Ernicke S, Bosse M, Kaiser A, Els-Heindl S, Krug U, Beck-Sickinger A, Meiler J, Huster D.

Structure. 2019 Mar 5;27(3):537-544.e4. doi: 10.1016/j.str.2018.12.004. Epub 2019 Jan 24.

PMID:
30686667
6.

Interaction of statins with phospholipid bilayers studied by solid-state NMR spectroscopy.

Galiullina LF, Scheidt HA, Huster D, Aganov A, Klochkov V.

Biochim Biophys Acta Biomembr. 2019 Mar 1;1861(3):584-593. doi: 10.1016/j.bbamem.2018.12.013. Epub 2018 Dec 20.

PMID:
30578770
7.

Amphiphilic Ionic Liquid-Induced Membrane Permeabilization: Binding Is Not Enough.

Kumar S, Scheidt HA, Kaur N, Kaur A, Kang TS, Huster D, Mithu VS.

J Phys Chem B. 2018 Jul 5;122(26):6763-6770. doi: 10.1021/acs.jpcb.8b03733. Epub 2018 Jun 20.

PMID:
29878782
8.

Transmembrane Helix Induces Membrane Fusion through Lipid Binding and Splay.

Scheidt HA, Kolocaj K, Veje Kristensen J, Huster D, Langosch D.

J Phys Chem Lett. 2018 Jun 21;9(12):3181-3186. doi: 10.1021/acs.jpclett.8b00859. Epub 2018 Jun 1.

PMID:
29799756
9.

Ring structure modifications of phenylalanine 19 increase fibrillation kinetics and reduce toxicity of amyloid β (1-40).

Korn A, Surendran D, Krueger M, Maiti S, Huster D.

Chem Commun (Camb). 2018 May 24;54(43):5430-5433. doi: 10.1039/c8cc01733f.

PMID:
29745414
10.

Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes.

Kamp F, Scheidt HA, Winkler E, Basset G, Heinel H, Hutchison JM, LaPointe LM, Sanders CR, Steiner H, Huster D.

ACS Chem Neurosci. 2018 Jul 18;9(7):1702-1713. doi: 10.1021/acschemneuro.8b00068. Epub 2018 May 11.

11.

[Prognostic relevance of tissue oxygen saturation in patients in the early stage of multiple organ dysfunction syndrome].

Huster D, Härtel F, Nuding S, Schroeder J, Zhang Y, Werdan K, Ebelt H.

Med Klin Intensivmed Notfmed. 2019 Mar;114(2):146-153. doi: 10.1007/s00063-018-0438-6. Epub 2018 Apr 18. German.

PMID:
29671035
12.

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.

Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B.

Nature. 2018 Apr;556(7702):520-524. doi: 10.1038/s41586-018-0046-x. Epub 2018 Apr 18.

13.

Probing the role of ceramide hydroxylation in skin barrier lipid models by 2H solid-state NMR spectroscopy and X-ray powder diffraction.

Kováčik A, Vogel A, Adler J, Pullmannová P, Vávrová K, Huster D.

Biochim Biophys Acta Biomembr. 2018 May;1860(5):1162-1170. doi: 10.1016/j.bbamem.2018.02.003. Epub 2018 Feb 22.

14.

Improved in Vitro Folding of the Y2 G Protein-Coupled Receptor into Bicelles.

Schmidt P, Bender BJ, Kaiser A, Gulati K, Scheidt HA, Hamm HE, Meiler J, Beck-Sickinger AG, Huster D.

Front Mol Biosci. 2018 Jan 17;4:100. doi: 10.3389/fmolb.2017.00100. eCollection 2017.

15.

[Wilson disease].

Huster D.

Internist (Berl). 2018 Feb;59(2):159-174. doi: 10.1007/s00108-017-0378-x. Review. German.

PMID:
29340742
16.

Amyloid β (1-40) Toxicity Depends on the Molecular Contact between Phenylalanine 19 and Leucine 34.

Korn A, McLennan S, Adler J, Krueger M, Surendran D, Maiti S, Huster D.

ACS Chem Neurosci. 2018 Apr 18;9(4):790-799. doi: 10.1021/acschemneuro.7b00360. Epub 2017 Dec 27.

PMID:
29232098
17.

[Diagnostics of Wilson's disease].

Hermann W, Huster D.

Nervenarzt. 2018 Feb;89(2):115-123. doi: 10.1007/s00115-017-0452-6. Review. German.

PMID:
29159549
18.

The Function of ATPase Copper Transporter ATP7B in Intestine.

Pierson H, Muchenditsi A, Kim BE, Ralle M, Zachos N, Huster D, Lutsenko S.

Gastroenterology. 2018 Jan;154(1):168-180.e5. doi: 10.1053/j.gastro.2017.09.019. Epub 2017 Sep 25.

19.

Perturbation of the F19-L34 Contact in Amyloid β (1-40) Fibrils Induces Only Local Structural Changes but Abolishes Cytotoxicity.

Hoffmann F, Adler J, Chandra B, Mote KR, Bekçioğlu-Neff G, Sebastiani D, Huster D.

J Phys Chem Lett. 2017 Oct 5;8(19):4740-4745. doi: 10.1021/acs.jpclett.7b02317. Epub 2017 Sep 18.

PMID:
28910107
20.

Pyroglutamate-Modified Amyloid β (11- 40) Fibrils Are More Toxic than Wildtype Fibrils but Structurally Very Similar.

Scheidt HA, Adler J, Zeitschel U, Höfling C, Korn A, Krueger M, Roßner S, Huster D.

Chemistry. 2017 Nov 7;23(62):15834-15838. doi: 10.1002/chem.201703909. Epub 2017 Oct 10.

PMID:
28857302
21.

The Potential of α-Spinasterol to Mimic the Membrane Properties of Natural Cholesterol.

Haralampiev I, Scheidt HA, Huster D, Müller P.

Molecules. 2017 Aug 22;22(8). pii: E1390. doi: 10.3390/molecules22081390.

22.

Influence of a Novel Dimeric Ceramide Molecule on the Nanostructure and Thermotropic Phase Behavior of a Stratum Corneum Model Mixture.

Stahlberg S, Eichner A, Sonnenberger S, Kováčik A, Lange S, Schmitt T, Demé B, Hauß T, Dobner B, Neubert RHH, Huster D.

Langmuir. 2017 Sep 12;33(36):9211-9221. doi: 10.1021/acs.langmuir.7b01227. Epub 2017 Aug 29.

PMID:
28819979
23.

Membrane properties of hydroxycholesterols related to the brain cholesterol metabolism.

Hilsch M, Haralampiev I, Müller P, Huster D, Scheidt HA.

Beilstein J Org Chem. 2017 Apr 18;13:720-727. doi: 10.3762/bjoc.13.71. eCollection 2017.

24.

Animal models of Wilson disease.

Medici V, Huster D.

Handb Clin Neurol. 2017;142:57-70. doi: 10.1016/B978-0-444-63625-6.00006-9. Review.

PMID:
28433110
25.

Expression, Functional Characterization, and Solid-State NMR Investigation of the G Protein-Coupled GHS Receptor in Bilayer Membranes.

Schrottke S, Kaiser A, Vortmeier G, Els-Heindl S, Worm D, Bosse M, Schmidt P, Scheidt HA, Beck-Sickinger AG, Huster D.

Sci Rep. 2017 Apr 7;7:46128. doi: 10.1038/srep46128.

26.

Phase separation in ceramide[NP] containing lipid model membranes: neutron diffraction and solid-state NMR.

Schroeter A, Stahlberg S, Školová B, Sonnenberger S, Eichner A, Huster D, Vávrová K, Hauß T, Dobner B, Neubert RH, Vogel A.

Soft Matter. 2017 Mar 8;13(10):2107-2119. doi: 10.1039/c6sm02356h.

PMID:
28225091
27.

Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor.

Lede V, Meusel A, Garten A, Popkova Y, Penke M, Franke C, Ricken A, Schulz A, Kiess W, Huster D, Schöneberg T, Schiller J.

PLoS One. 2017 Feb 16;12(2):e0172000. doi: 10.1371/journal.pone.0172000. eCollection 2017.

28.

Stereoisomers Probe Steric Zippers in Amyloid-β.

Chandra B, Korn A, Maity BK, Adler J, Rawat A, Krueger M, Huster D, Maiti S.

J Phys Chem B. 2017 Mar 2;121(8):1835-1842. doi: 10.1021/acs.jpcb.6b12332. Epub 2017 Feb 14.

PMID:
28140589
29.

Influence of the penetration enhancer isopropyl myristate on stratum corneum lipid model membranes revealed by neutron diffraction and 2H NMR experiments.

Eichner A, Stahlberg S, Sonnenberger S, Lange S, Dobner B, Ostermann A, Schrader TE, Hauß T, Schroeter A, Huster D, Neubert RH.

Biochim Biophys Acta Biomembr. 2017 May;1859(5):745-755. doi: 10.1016/j.bbamem.2017.01.029. Epub 2017 Jan 26.

30.

The Intrinsic Pepsin Resistance of Interleukin-8 Can Be Explained from a Combined Bioinformatical and Experimental Approach.

Anders G, Hassiepen U, Theisgen S, Heymann S, Muller L, Panigada T, Huster D, Samsonov SA.

IEEE/ACM Trans Comput Biol Bioinform. 2018 Jan-Feb;15(1):300-308. doi: 10.1109/TCBB.2016.2614821. Epub 2016 Oct 3.

PMID:
28113517
31.

Severe Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein Receptor.

Lede V, Franke C, Meusel A, Teupser D, Ricken A, Thiery J, Schiller J, Huster D, Schöneberg T, Schulz A.

PLoS One. 2016 Dec 28;11(12):e0167888. doi: 10.1371/journal.pone.0167888. eCollection 2016.

32.

N-terminal lipid conjugation of amyloid β(1-40) leads to the formation of highly ordered N-terminally extended fibrils.

Adler J, Scheidt HA, Lemmnitzer K, Krueger M, Huster D.

Phys Chem Chem Phys. 2017 Jan 18;19(3):1839-1846. doi: 10.1039/c6cp05982a.

PMID:
28000812
33.

Erratum to: Lack of functional P2X7 receptor aggravates brain edema development after middle cerebral artery occlusion.

Kaiser M, Penk A, Franke H, Krügel U, Nörenberg W, Huster D, Schaefer M.

Purinergic Signal. 2016 Dec;12(4):735-736. No abstract available.

34.

Fibrils of Truncated Pyroglutamyl-Modified Aβ Peptide Exhibit a Similar Structure as Wildtype Mature Aβ Fibrils.

Scheidt HA, Adler J, Krueger M, Huster D.

Sci Rep. 2016 Sep 21;6:33531. doi: 10.1038/srep33531.

35.

The interaction of sorafenib and regorafenib with membranes is modulated by their lipid composition.

Haralampiev I, Scheidt HA, Abel T, Luckner M, Herrmann A, Huster D, Müller P.

Biochim Biophys Acta. 2016 Nov;1858(11):2871-2881. doi: 10.1016/j.bbamem.2016.08.014. Epub 2016 Aug 28.

36.

The structural investigation of glycosaminoglycan binding to CXCL12 displays distinct interaction sites.

Panitz N, Theisgen S, Samsonov SA, Gehrcke JP, Baumann L, Bellmann-Sickert K, Köhling S, Pisabarro MT, Rademann J, Huster D, Beck-Sickinger AG.

Glycobiology. 2016 Nov;26(11):1209-1221. doi: 10.1093/glycob/cww059. Epub 2016 Jun 24.

PMID:
27496764
37.

A Detailed Analysis of the Morphology of Fibrils of Selectively Mutated Amyloid β (1-40).

Adler J, Baumann M, Voigt B, Scheidt HA, Bhowmik D, Häupl T, Abel B, Madhu PK, Balbach J, Maiti S, Huster D.

Chemphyschem. 2016 Sep 5;17(17):2744-53. doi: 10.1002/cphc.201600413. Epub 2016 Jun 27.

PMID:
27224205
38.

Amyloid Beta Aggregation in the Presence of Temperature-Sensitive Polymers.

Funtan S, Evgrafova Z, Adler J, Huster D, Binder WH.

Polymers (Basel). 2016 May 2;8(5). pii: E178. doi: 10.3390/polym8050178.

39.

Lack of functional P2X7 receptor aggravates brain edema development after middle cerebral artery occlusion.

Kaiser M, Penk A, Franke H, Krügel U, Nörenberg W, Huster D, Schaefer M.

Purinergic Signal. 2016 Sep;12(3):453-63. doi: 10.1007/s11302-016-9511-x. Epub 2016 Apr 5. Erratum in: Purinergic Signal. 2016 Dec;12 (4):735-736.

40.

The adrenal specific toxicant mitotane directly interacts with lipid membranes and alters membrane properties depending on lipid composition.

Scheidt HA, Haralampiev I, Theisgen S, Schirbel A, Sbiera S, Huster D, Kroiss M, Müller P.

Mol Cell Endocrinol. 2016 Jun 15;428:68-81. doi: 10.1016/j.mce.2016.03.022. Epub 2016 Mar 18.

PMID:
27002491
41.

Chemoenzymatic Synthesis of Nonasulfated Tetrahyaluronan with a Paramagnetic Tag for Studying Its Complex with Interleukin-10.

Köhling S, Künze G, Lemmnitzer K, Bermudez M, Wolber G, Schiller J, Huster D, Rademann J.

Chemistry. 2016 Apr 11;22(16):5563-74. doi: 10.1002/chem.201504459. Epub 2016 Feb 25.

PMID:
26918733
42.

A preliminary technical study on sodium dodecyl sulfate-induced changes of the nano-structural and macro-mechanical properties in human iliotibial tract specimens.

Hammer N, Huster D, Boldt A, Hädrich C, Koch H, Möbius R, Schulze-Tanzil G, Scheidt HA.

J Mech Behav Biomed Mater. 2016 Aug;61:164-173. doi: 10.1016/j.jmbbm.2016.01.018. Epub 2016 Jan 26.

PMID:
26866452
43.

Probing the Role of Ceramide Headgroup Polarity in Short-Chain Model Skin Barrier Lipid Mixtures by ²H Solid-State NMR Spectroscopy.

Stahlberg S, Lange S, Dobner B, Huster D.

Langmuir. 2016 Mar 1;32(8):2023-31. doi: 10.1021/acs.langmuir.5b04173. Epub 2016 Feb 15.

PMID:
26828109
44.

Structure and dynamics of the aliphatic cholesterol side chain in membranes as studied by (2)H NMR spectroscopy and molecular dynamics simulation.

Vogel A, Scheidt HA, Baek DJ, Bittman R, Huster D.

Phys Chem Chem Phys. 2016 Feb 7;18(5):3730-8. doi: 10.1039/c5cp05084g.

PMID:
26762541
45.

A Selective Mucin/Methylcellulose Hybrid Gel with Tailored Mechanical Properties.

Nowald C, Penk A, Chiu HY, Bein T, Huster D, Lieleg O.

Macromol Biosci. 2016 Apr;16(4):567-79. doi: 10.1002/mabi.201500353. Epub 2016 Jan 8.

PMID:
26748668
46.

Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease in Atp7B(-/-) (Wilson disease) mice.

Hamilton JP, Koganti L, Muchenditsi A, Pendyala VS, Huso D, Hankin J, Murphy RC, Huster D, Merle U, Mangels C, Yang N, Potter JJ, Mezey E, Lutsenko S.

Hepatology. 2016 Jun;63(6):1828-41. doi: 10.1002/hep.28406. Epub 2016 Feb 22.

47.

Identification of the Glycosaminoglycan Binding Site of Interleukin-10 by NMR Spectroscopy.

Künze G, Köhling S, Vogel A, Rademann J, Huster D.

J Biol Chem. 2016 Feb 5;291(6):3100-13. doi: 10.1074/jbc.M115.681759. Epub 2015 Dec 16.

48.

Micro- and nano-tubules built from loosely and tightly rolled up thin sheets.

Losensky L, Goldenbogen B, Holland G, Laue M, Petran A, Liebscher J, Scheidt HA, Vogel A, Huster D, Klipp E, Arbuzova A.

Phys Chem Chem Phys. 2016 Jan 14;18(2):1292-301. doi: 10.1039/c5cp06084b.

PMID:
26659839
49.

Scleral cross-linking by riboflavin and blue light application in young rabbits: damage threshold and eye growth inhibition.

Iseli HP, Körber N, Koch C, Karl A, Penk A, Huster D, Reichenbach A, Wiedemann P, Francke M.

Graefes Arch Clin Exp Ophthalmol. 2016 Jan;254(1):109-22. doi: 10.1007/s00417-015-3213-x. Epub 2015 Nov 23.

PMID:
26597112
50.

Influence of the sterol aliphatic side chain on membrane properties: a molecular dynamics study.

Robalo JR, Ramalho JP, Huster D, Loura LM.

Phys Chem Chem Phys. 2015 Sep 21;17(35):22736-48. doi: 10.1039/c5cp03097h. Epub 2015 Aug 10.

PMID:
26255832

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