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Items: 10


Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

Hart T, Tong AHY, Chan K, Van Leeuwen J, Seetharaman A, Aregger M, Chandrashekhar M, Hustedt N, Seth S, Noonan A, Habsid A, Sizova O, Nedyalkova L, Climie R, Tworzyanski L, Lawson K, Sartori MA, Alibeh S, Tieu D, Masud S, Mero P, Weiss A, Brown KR, Usaj M, Billmann M, Rahman M, Constanzo M, Myers CL, Andrews BJ, Boone C, Durocher D, Moffat J.

G3 (Bethesda). 2017 Aug 7;7(8):2719-2727. doi: 10.1534/g3.117.041277.


The control of DNA repair by the cell cycle.

Hustedt N, Durocher D.

Nat Cell Biol. 2016 Dec 23;19(1):1-9. doi: 10.1038/ncb3452. Review.


RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together.

Seeber A, Hegnauer AM, Hustedt N, Deshpande I, Poli J, Eglinger J, Pasero P, Gut H, Shinohara M, Hopfner KP, Shimada K, Gasser SM.

Mol Cell. 2016 Dec 1;64(5):951-966. doi: 10.1016/j.molcel.2016.10.032. Epub 2016 Nov 23.


Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress.

Poli J, Gerhold CB, Tosi A, Hustedt N, Seeber A, Sack R, Herzog F, Pasero P, Shimada K, Hopfner KP, Gasser SM.

Genes Dev. 2016 Feb 1;30(3):337-54. doi: 10.1101/gad.273813.115. Epub 2016 Jan 21.


Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.

Hustedt N, Seeber A, Sack R, Tsai-Pflugfelder M, Bhullar B, Vlaming H, van Leeuwen F, Guénolé A, van Attikum H, Srivas R, Ideker T, Shimada K, Gasser SM.

Mol Cell. 2015 Jan 22;57(2):273-89. doi: 10.1016/j.molcel.2014.11.016. Epub 2014 Dec 18.


Analyzing DNA replication checkpoint in budding yeast.

Hustedt N, Shimada K.

Methods Mol Biol. 2014;1170:321-41. doi: 10.1007/978-1-4939-0888-2_16.


Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores.

Heinrich S, Sewart K, Windecker H, Langegger M, Schmidt N, Hustedt N, Hauf S.

EMBO Rep. 2014 Mar;15(3):291-8. doi: 10.1002/embr.201338114. Epub 2014 Jan 29.


Replication checkpoint: tuning and coordination of replication forks in s phase.

Hustedt N, Gasser SM, Shimada K.

Genes (Basel). 2013 Aug 19;4(3):388-434. doi: 10.3390/genes4030388.


Mph1 kinetochore localization is crucial and upstream in the hierarchy of spindle assembly checkpoint protein recruitment to kinetochores.

Heinrich S, Windecker H, Hustedt N, Hauf S.

J Cell Sci. 2012 Oct 15;125(Pt 20):4720-7. doi: 10.1242/jcs.110387. Epub 2012 Jul 23.


An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.

Hegnauer AM, Hustedt N, Shimada K, Pike BL, Vogel M, Amsler P, Rubin SM, van Leeuwen F, Guénolé A, van Attikum H, Thomä NH, Gasser SM.

EMBO J. 2012 Sep 12;31(18):3768-83. doi: 10.1038/emboj.2012.195. Epub 2012 Jul 20.

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