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Items: 44

1.

Early Surgical Outcome of Endoscopic Third Ventriculostomy in the Management of Obstructive Hydrocephalus: A Randomized Control Trial.

Rahman MM, Salam MA, Uddin K, Rahman MM, Islam MR, Haque MA, Hussain AR, Yusuf MA.

Asian J Neurosurg. 2018 Oct-Dec;13(4):1001-1004. doi: 10.4103/ajns.AJNS_376_16.

2.

XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis.

Hussain AR, Siraj AK, Ahmed M, Bu R, Pratheeshkumar P, Alrashed AM, Qadri Z, Ajarim D, Al-Dayel F, Beg S, Al-Kuraya KS.

BMC Cancer. 2017 Sep 11;17(1):640. doi: 10.1186/s12885-017-3627-4.

3.

Molecular surveillance of Theileria parasites of livestock in Oman.

Al-Fahdi A, Alqamashoui B, Al-Hamidhi S, Kose O, Tageldin MH, Bobade P, Johnson EH, Hussain AR, Karagenc T, Tait A, Shiels B, Bilgic HB, Babiker H.

Ticks Tick Borne Dis. 2017 Aug;8(5):741-748. doi: 10.1016/j.ttbdis.2017.05.008. Epub 2017 May 21.

PMID:
28558992
4.

Co-targeting of Cyclooxygenase-2 and FoxM1 is a viable strategy in inducing anticancer effects in colorectal cancer cells.

Ahmed M, Hussain AR, Siraj AK, Uddin S, Al-Sanea N, Al-Dayel F, Al-Assiri M, Beg S, Al-Kuraya KS.

Mol Cancer. 2015 Jul 10;14:131. doi: 10.1186/s12943-015-0406-1.

5.

Dual Targeting of mTOR Activity with Torin2 Potentiates Anticancer Effects of Cisplatin in Epithelial Ovarian Cancer.

Hussain AR, Al-Romaizan M, Ahmed M, Thangavel S, Al-Dayel F, Beg S, Uddin S, Siraj AK, Al-Kuraya KS.

Mol Med. 2015 May 26;21:466-78. doi: 10.2119/molmed.2014.00238.

6.

Role of X-Linked Inhibitor of Apoptosis as a Prognostic Marker and Therapeutic Target in Papillary Thyroid Carcinoma.

Hussain AR, Bu R, Ahmed M, Jehan Z, Beg S, Al-Sobhi S, Al-Dayel F, Siraj AK, Uddin S, Al-Kuraya KS.

J Clin Endocrinol Metab. 2015 Jul;100(7):E974-85. doi: 10.1210/jc.2014-4356. Epub 2015 May 14.

PMID:
25974735
7.

Detection of human cytomegalovirus in different histopathological types of glioma in Iraqi patients.

Shamran HA, Kadhim HS, Hussain AR, Kareem A, Taub DD, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP.

Biomed Res Int. 2015;2015:642652. doi: 10.1155/2015/642652. Epub 2015 Feb 1.

8.

Pattern of neurological disease seen among patients admitted in tertiary care hospital.

Chowdhury RN, Hasan AT, Ur Rahman Y, Khan SI, Hussain AR, Ahsan S.

BMC Res Notes. 2014 Mar 31;7:202. doi: 10.1186/1756-0500-7-202.

9.

High prevalence of mTOR complex activity can be targeted using Torin2 in papillary thyroid carcinoma.

Ahmed M, Hussain AR, Bavi P, Ahmed SO, Al Sobhi SS, Al-Dayel F, Uddin S, Al-Kuraya KS.

Carcinogenesis. 2014 Jul;35(7):1564-72. doi: 10.1093/carcin/bgu051. Epub 2014 Feb 28.

PMID:
24583924
10.

Role of dysregulated expression of leptin and leptin receptors in colorectal carcinogenesis.

Uddin S, Hussain AR, Khan OS, Al-Kuraya KS.

Tumour Biol. 2014 Feb;35(2):871-9. doi: 10.1007/s13277-013-1166-4. Epub 2013 Sep 7. Review.

PMID:
24014051
12.

Bortezomib inhibits proteasomal degradation of IκBα and induces mitochondrial dependent apoptosis in activated B-cell diffuse large B-cell lymphoma.

Bu R, Hussain AR, Al-Obaisi KA, Ahmed M, Uddin S, Al-Kuraya KS.

Leuk Lymphoma. 2014 Feb;55(2):415-24. doi: 10.3109/10428194.2013.806799. Epub 2013 Jun 24.

PMID:
23697845
13.

Phosphorylated IκBα predicts poor prognosis in activated B-cell lymphoma and its inhibition with thymoquinone induces apoptosis via ROS release.

Hussain AR, Uddin S, Ahmed M, Al-Dayel F, Bavi PP, Al-Kuraya KS.

PLoS One. 2013;8(3):e60540. doi: 10.1371/journal.pone.0060540. Epub 2013 Mar 28.

14.

Cross-talk between NFkB and the PI3-kinase/AKT pathway can be targeted in primary effusion lymphoma (PEL) cell lines for efficient apoptosis.

Hussain AR, Ahmed SO, Ahmed M, Khan OS, Al Abdulmohsen S, Platanias LC, Al-Kuraya KS, Uddin S.

PLoS One. 2012;7(6):e39945. doi: 10.1371/journal.pone.0039945. Epub 2012 Jun 29. Erratum in: PLoS One. 2014;9(3):e92484.

15.

Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma.

Uddin S, Hussain AR, Ahmed M, Siddiqui K, Al-Dayel F, Bavi P, Al-Kuraya KS.

Haematologica. 2012 Jul;97(7):1092-100. doi: 10.3324/haematol.2011.053421. Epub 2012 Jan 22.

16.

c-Met inhibitor synergizes with tumor necrosis factor-related apoptosis-induced ligand to induce papillary thyroid carcinoma cell death.

Bu R, Uddin S, Ahmed M, Hussain AR, Alsobhi S, Amin T, Al-Nuaim A, Al-Dayel F, Abubaker J, Bavi P, Al-Kuraya KS.

Mol Med. 2012 Mar 27;18:167-77. doi: 10.2119/molmed.2011.00238.

17.

Role of leptin and its receptors in the pathogenesis of thyroid cancer.

Uddin S, Hussain AR, Siraj AK, Khan OS, Bavi PP, Al-Kuraya KS.

Int J Clin Exp Pathol. 2011;4(7):637-43. Epub 2011 Oct 3. Review.

18.

FoxM1 and its association with matrix metalloproteinases (MMP) signaling pathway in papillary thyroid carcinoma.

Ahmed M, Uddin S, Hussain AR, Alyan A, Jehan Z, Al-Dayel F, Al-Nuaim A, Al-Sobhi S, Amin T, Bavi P, Al-Kuraya KS.

J Clin Endocrinol Metab. 2012 Jan;97(1):E1-E13. doi: 10.1210/jc.2011-1506. Epub 2011 Nov 2.

PMID:
22049175
19.

Coexpression of activated c-Met and death receptor 5 predicts better survival in colorectal carcinoma.

Uddin S, Hussain AR, Ahmed M, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Bavi P, Al-Kuraya KS.

Am J Pathol. 2011 Dec;179(6):3032-44. doi: 10.1016/j.ajpath.2011.08.007. Epub 2011 Oct 5.

20.

Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines.

Hussain AR, Uddin S, Bu R, Khan OS, Ahmed SO, Ahmed M, Al-Kuraya KS.

PLoS One. 2011;6(9):e24703. doi: 10.1371/journal.pone.0024703. Epub 2011 Sep 12.

21.

Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma.

Bavi P, Uddin S, Ahmed M, Jehan Z, Bu R, Abubaker J, Sultana M, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Prabhakaran S, Hussain AR, Al-Kuraya KS.

Am J Pathol. 2011 May;178(5):2109-20. doi: 10.1016/j.ajpath.2011.01.034.

22.

The biological and clinical impact of inhibition of NF-κB-initiated apoptosis in diffuse large B cell lymphoma (DLBCL).

Bavi P, Uddin S, Bu R, Ahmed M, Abubaker J, Balde V, Qadri Z, Ajarim D, Al-Dayel F, Hussain AR, Al-Kuraya KS.

J Pathol. 2011 Jul;224(3):355-66. doi: 10.1002/path.2864. Epub 2011 Apr 19.

PMID:
21506127
23.

Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma.

Hussain AR, Ahmed M, Ahmed S, Manogaran P, Platanias LC, Alvi SN, Al-Kuraya KS, Uddin S.

Free Radic Biol Med. 2011 Apr 15;50(8):978-87. doi: 10.1016/j.freeradbiomed.2010.12.034. Epub 2011 Jan 4.

PMID:
21215312
24.

Demethylation of TMS1 gene sensitizes thyroid cancer cells to TRAIL-induced apoptosis.

Siraj AK, Hussain AR, Al-Rasheed M, Ahmed M, Bavi P, Alsobhi SA, Al-Nuaim A, Uddin S, Al-Kuraya K.

J Clin Endocrinol Metab. 2011 Jan;96(1):E215-24. doi: 10.1210/jc.2010-0790. Epub 2010 Oct 6.

PMID:
20926535
25.

Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations.

Bavi P, Prabhakaran SE, Abubaker J, Qadri Z, George T, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Hussain AR, Uddin S, Al-Kuraya KS.

Mol Cancer. 2010 Jul 30;9:203. doi: 10.1186/1476-4598-9-203.

26.

HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma.

Bu R, Uddin S, Bavi P, Hussain AR, Al-Dayel F, Ghourab S, Ahmed M, Al-Kuraya KS.

Lab Invest. 2011 Jan;91(1):124-37. doi: 10.1038/labinvest.2010.136. Epub 2010 Jul 26.

27.

Prognostic significance of XIAP expression in DLBCL and effect of its inhibition on AKT signalling.

Hussain AR, Uddin S, Ahmed M, Bu R, Ahmed SO, Abubaker J, Sultana M, Ajarim D, Al-Dayel F, Bavi PP, Al-Kuraya KS.

J Pathol. 2010 Oct;222(2):180-90. doi: 10.1002/path.2747.

PMID:
20632385
28.

Inhibition of c-MET is a potential therapeutic strategy for treatment of diffuse large B-cell lymphoma.

Uddin S, Hussain AR, Ahmed M, Al-Dayel F, Bu R, Bavi P, Al-Kuraya KS.

Lab Invest. 2010 Sep;90(9):1346-56. doi: 10.1038/labinvest.2010.108. Epub 2010 Jun 7.

29.

Leptin receptor expression and its association with PI3K/AKT signaling pathway in diffuse large B-cell lymphoma.

Uddin S, Bu R, Ahmed M, Hussain AR, Ajarim D, Al-Dayel F, Bavi P, Al-kuraya KS.

Leuk Lymphoma. 2010 Jul;51(7):1305-14. doi: 10.3109/10428191003802365.

PMID:
20443680
30.

Inhibition of fatty acid synthase suppresses c-Met receptor kinase and induces apoptosis in diffuse large B-cell lymphoma.

Uddin S, Hussain AR, Ahmed M, Bu R, Ahmed SO, Ajarim D, Al-Dayel F, Bavi P, Al-Kuraya KS.

Mol Cancer Ther. 2010 May;9(5):1244-55. doi: 10.1158/1535-7163.MCT-09-1061. Epub 2010 Apr 27.

31.

Apigenin induces apoptosis via downregulation of S-phase kinase-associated protein 2-mediated induction of p27Kip1 in primary effusion lymphoma cells.

Hussain AR, Khan AS, Ahmed SO, Ahmed M, Platanias LC, Al-Kuraya KS, Uddin S.

Cell Prolif. 2010 Apr;43(2):170-83. doi: 10.1111/j.1365-2184.2009.00662.x. Epub 2010 Jan 14.

PMID:
20074295
32.

Leptin-R and its association with PI3K/AKT signaling pathway in papillary thyroid carcinoma.

Uddin S, Bavi P, Siraj AK, Ahmed M, Al-Rasheed M, Hussain AR, Ahmed M, Amin T, Alzahrani A, Al-Dayel F, Abubaker J, Bu R, Al-Kuraya KS.

Endocr Relat Cancer. 2010 Feb 18;17(1):191-202. doi: 10.1677/ERC-09-0153. Print 2010 Mar.

PMID:
20008098
33.

Bortezomib-mediated expression of p27Kip1 through S-phase kinase protein 2 degradation in epithelial ovarian cancer.

Uddin S, Ahmed M, Hussain AR, Jehan Z, Al-Dayel F, Munkarah A, Bavi P, Al-Kuraya KS.

Lab Invest. 2009 Oct;89(10):1115-27. doi: 10.1038/labinvest.2009.75. Epub 2009 Jul 27.

34.

Proteasome inhibitor MG-132 mediated expression of p27Kip1 via S-phase kinase protein 2 degradation induces cell cycle coupled apoptosis in primary effusion lymphoma cells.

Hussain AR, Ahmed M, Ahmed SO, Al-Thari S, Khan AS, Razack S, Platanias LC, Al-Kuraya KS, Uddin S.

Leuk Lymphoma. 2009 Jul;50(7):1204-13. doi: 10.1080/10428190902951799.

PMID:
19557642
35.

Leptin receptor expression in Middle Eastern colorectal cancer and its potential clinical implication.

Uddin S, Bavi PP, Hussain AR, Alsbeih G, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Ahmed M, Al-Kuraya KS.

Carcinogenesis. 2009 Nov;30(11):1832-40. doi: 10.1093/carcin/bgp145. Epub 2009 Jun 11.

PMID:
19520793
36.

High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.

Uddin S, Hussain AR, Ahmed M, Abubaker J, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Bavi P, Al-Kuraya KS.

Am J Gastroenterol. 2009 Jul;104(7):1790-801. doi: 10.1038/ajg.2009.230. Epub 2009 Jun 2.

PMID:
19491830
37.

Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines.

Hussain AR, Ahmed M, Al-Jomah NA, Khan AS, Manogaran P, Sultana M, Abubaker J, Platanias LC, Al-Kuraya KS, Uddin S.

Mol Cancer Ther. 2008 Oct;7(10):3318-29. doi: 10.1158/1535-7163.MCT-08-0541.

38.

Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers.

Uddin S, Siraj AK, Al-Rasheed M, Ahmed M, Bu R, Myers JN, Al-Nuaim A, Al-Sobhi S, Al-Dayel F, Bavi P, Hussain AR, Al-Kuraya KS.

J Clin Endocrinol Metab. 2008 Oct;93(10):4088-97. doi: 10.1210/jc.2008-0503. Epub 2008 Aug 5.

PMID:
18682509
39.

Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.

Uddin S, Ahmed M, Bavi P, El-Sayed R, Al-Sanea N, AbdulJabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Hussain AR, Al-Kuraya KS.

Cancer Res. 2008 May 1;68(9):3379-88. doi: 10.1158/0008-5472.CAN-07-6109.

40.

Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells.

Hussain AR, Al-Jomah NA, Siraj AK, Manogaran P, Al-Hussein K, Abubaker J, Platanias LC, Al-Kuraya KS, Uddin S.

Cancer Res. 2007 Apr 15;67(8):3888-97.

41.

Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival.

Uddin S, Hussain AR, Siraj AK, Manogaran PS, Al-Jomah NA, Moorji A, Atizado V, Al-Dayel F, Belgaumi A, El-Solh H, Ezzat A, Bavi P, Al-Kuraya KS.

Blood. 2006 Dec 15;108(13):4178-86. Epub 2006 Aug 31.

PMID:
16946303
42.

Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias.

Hussain AR, Al-Rasheed M, Manogaran PS, Al-Hussein KA, Platanias LC, Al Kuraya K, Uddin S.

Apoptosis. 2006 Feb;11(2):245-54.

PMID:
16502262
43.

Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma.

Uddin S, Hussain AR, Manogaran PS, Al-Hussein K, Platanias LC, Gutierrez MI, Bhatia KG.

Oncogene. 2005 Oct 27;24(47):7022-30.

PMID:
16044161
44.

Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.

Uddin S, Hussain AR, Al-Hussein KA, Manogaran PS, Wickrema A, Gutierrez MI, Bhatia KG.

Clin Cancer Res. 2005 Apr 15;11(8):3102-8.

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