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Items: 35

1.

Remembering Zhores Medvedev, a multi-talented biogerontologist (1925-2018).

Huschtscha LI.

Biogerontology. 2019 Jun;20(3):377-379. doi: 10.1007/s10522-019-09810-9. No abstract available.

PMID:
31030310
2.

Is cell culture a risky business? Risk analysis based on scientist survey data.

Shannon M, Capes-Davis A, Eggington E, Georghiou R, Huschtscha LI, Moy E, Power M, Reddel RR, Arthur JW.

Int J Cancer. 2016 Feb 1;138(3):664-70. doi: 10.1002/ijc.29817. Epub 2015 Sep 14.

3.

ATRX represses alternative lengthening of telomeres.

Napier CE, Huschtscha LI, Harvey A, Bower K, Noble JR, Hendrickson EA, Reddel RR.

Oncotarget. 2015 Jun 30;6(18):16543-58.

4.

Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis.

Locke WJ, Zotenko E, Stirzaker C, Robinson MD, Hinshelwood RA, Stone A, Reddel RR, Huschtscha LI, Clark SJ.

Clin Epigenetics. 2015 May 1;7:52. doi: 10.1186/s13148-015-0086-0. eCollection 2015.

5.

STC1 expression is associated with tumor growth and metastasis in breast cancer.

Chang AC, Doherty J, Huschtscha LI, Redvers R, Restall C, Reddel RR, Anderson RL.

Clin Exp Metastasis. 2015 Jan;32(1):15-27. doi: 10.1007/s10585-014-9687-9. Epub 2014 Nov 13.

PMID:
25391215
6.

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease.

Hilton HN, Doan TB, Graham JD, Oakes SR, Silvestri A, Santucci N, Kantimm S, Huschtscha LI, Ormandy CJ, Funder JW, Simpson ER, Kuczek ES, Leedman PJ, Tilley WD, Fuller PJ, Muscat GE, Clarke CL.

Oncotarget. 2014 Sep 30;5(18):8651-64.

7.

Progesterone stimulates progenitor cells in normal human breast and breast cancer cells.

Hilton HN, Santucci N, Silvestri A, Kantimm S, Huschtscha LI, Graham JD, Clarke CL.

Breast Cancer Res Treat. 2014 Feb;143(3):423-33. doi: 10.1007/s10549-013-2817-2. Epub 2014 Jan 7.

PMID:
24395108
8.

Enhanced isolation of fibroblasts from human skin explants.

Huschtscha LI, Napier CE, Noble JR, Bower K, Au AY, Campbell HG, Braithwaite AW, Reddel RR.

Biotechniques. 2012 Oct;53(4):239-44. doi: 10.2144/0000113939.

9.

Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast.

Hilton HN, Graham JD, Kantimm S, Santucci N, Cloosterman D, Huschtscha LI, Mote PA, Clarke CL.

Mol Cell Endocrinol. 2012 Sep 25;361(1-2):191-201. doi: 10.1016/j.mce.2012.04.010. Epub 2012 May 2.

PMID:
22580007
10.

Five dysfunctional telomeres predict onset of senescence in human cells.

Kaul Z, Cesare AJ, Huschtscha LI, Neumann AA, Reddel RR.

EMBO Rep. 2011 Dec 23;13(1):52-9. doi: 10.1038/embor.2011.227.

11.

Hormone-responsive model of primary human breast epithelium.

Graham JD, Mote PA, Salagame U, Balleine RL, Huschtscha LI, Clarke CL.

J Mammary Gland Biol Neoplasia. 2009 Dec;14(4):367-79. doi: 10.1007/s10911-009-9160-6. Epub 2009 Nov 21.

PMID:
19936891
12.

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.

Henson JD, Cao Y, Huschtscha LI, Chang AC, Au AY, Pickett HA, Reddel RR.

Nat Biotechnol. 2009 Dec;27(12):1181-5. doi: 10.1038/nbt.1587.

PMID:
19935656
13.

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.

Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ; kConFab, Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ.

Nat Med. 2009 Aug;15(8):907-13. doi: 10.1038/nm.2000. Epub 2009 Aug 2.

PMID:
19648928
14.

Normal human mammary epithelial cells proliferate rapidly in the presence of elevated levels of the tumor suppressors p53 and p21(WAF1/CIP1).

Huschtscha LI, Moore JD, Noble JR, Campbell HG, Royds JA, Braithwaite AW, Reddel RR.

J Cell Sci. 2009 Aug 15;122(Pt 16):2989-95. doi: 10.1242/jcs.044107. Epub 2009 Jul 28.

15.

Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.

Hinshelwood RA, Melki JR, Huschtscha LI, Paul C, Song JZ, Stirzaker C, Reddel RR, Clark SJ.

Hum Mol Genet. 2009 Aug 15;18(16):3098-109. doi: 10.1093/hmg/ddp251. Epub 2009 May 28.

PMID:
19477956
16.

DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast.

Graham JD, Mote PA, Salagame U, van Dijk JH, Balleine RL, Huschtscha LI, Reddel RR, Clarke CL.

Endocrinology. 2009 Jul;150(7):3318-26. doi: 10.1210/en.2008-1630. Epub 2009 Apr 2.

17.

Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels.

Cao Y, Huschtscha LI, Nouwens AS, Pickett HA, Neumann AA, Chang AC, Toouli CD, Bryan TM, Reddel RR.

Cancer Res. 2008 May 1;68(9):3115-23. doi: 10.1158/0008-5472.CAN-07-6377.

18.

Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis.

Hinshelwood RA, Huschtscha LI, Melki J, Stirzaker C, Abdipranoto A, Vissel B, Ravasi T, Wells CA, Hume DA, Reddel RR, Clark SJ.

Cancer Res. 2007 Dec 15;67(24):11517-27.

19.

Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit.

Toouli CD, Huschtscha LI, Neumann AA, Noble JR, Colgin LM, Hukku B, Reddel RR.

Oncogene. 2002 Jan 3;21(1):128-39.

20.
21.

Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body.

Yeager TR, Neumann AA, Englezou A, Huschtscha LI, Noble JR, Reddel RR.

Cancer Res. 1999 Sep 1;59(17):4175-9.

22.

p16(INK4a) and the control of cellular proliferative life span.

Huschtscha LI, Reddel RR.

Carcinogenesis. 1999 Jun;20(6):921-6.

PMID:
10357768
23.

Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells.

Huschtscha LI, Noble JR, Neumann AA, Moy EL, Barry P, Melki JR, Clark SJ, Reddel RR.

Cancer Res. 1998 Aug 15;58(16):3508-12.

24.

A proton magnetic resonance spectroscopy study of aging and transformed human fibroblasts.

Rutter A, Mackinnon WB, Huschtscha LI, Mountford CE.

Exp Gerontol. 1996 Nov-Dec;31(6):669-86.

PMID:
9415096
25.

Characteristics of cancer cell death after exposure to cytotoxic drugs in vitro.

Huschtscha LI, Bartier WA, Ross CE, Tattersall MH.

Br J Cancer. 1996 Jan;73(1):54-60.

26.

Identification of apoptotic and necrotic human leukemic cells by flow cytometry.

Huschtscha LI, Jeitner TM, Andersson CE, Bartier WA, Tattersall MH.

Exp Cell Res. 1994 May;212(1):161-5.

PMID:
8174637
27.
28.

A rapid micro method for counting cells "in situ" using a fluorogenic alkaline phosphatase enzyme assay.

Huschtscha LI, Lucibello FC, Bodmer WF.

In Vitro Cell Dev Biol. 1989 Jan;25(1):105-8.

PMID:
2914812
29.

The susceptibility of Werner's syndrome and other human skin fibroblasts to SV40-induced transformation and immortalization.

Huschtscha LI, Thompson KV, Holliday R.

Proc R Soc Lond B Biol Sci. 1986 Oct 22;229(1254):1-12.

PMID:
2878433
30.

Experimental studies on Werner's syndrome fibroblasts.

Holliday R, Thompson KV, Huschtscha LI, Rattan SI, Sedgwick SG, Spanos A.

Adv Exp Med Biol. 1985;190:331-9. No abstract available.

PMID:
3002149
31.
32.

Cellular aging: further evidence for the commitment theory.

Holliday R, Huschtscha LI, Kirkwood TB.

Science. 1981 Sep 25;213(4515):1505-8.

PMID:
7280670
33.

Testing the commitment theory of cellular aging.

Holliday R, Huschtscha LI, Tarrant GM, Kirkwood TB.

Science. 1977 Oct 28;198(4315):366-72.

PMID:
910134
34.

Age changes of the pattern of F1 histone subfractions in rat liver and spleen chromatin.

Medvedev ZA, Medvedeva MN, Huschtscha LI.

Gerontology. 1977;23(5):334-41.

PMID:
856667
35.

The methionine-containing subfraction of F1 histone from rat tissues.

Medvedeva MN, Huschtscha LI, Medvedev ZA.

FEBS Lett. 1975 May 1;53(2):253-7. No abstract available.

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