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Items: 1 to 50 of 102

1.

The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.

Laforge M, Silvestre R, Rodrigues V, Garibal J, Campillo-Gimenez L, Mouhamad S, Monceaux V, Cumont MC, Rabezanahary H, Pruvost A, Cordeiro-da-Silva A, Hurtrel B, Silvestri G, Senik A, Estaquier J.

J Clin Invest. 2018 Apr 2;128(4):1627-1640. doi: 10.1172/JCI95127. Epub 2018 Mar 19.

2.

HIV/SIV infection primes monocytes and dendritic cells for apoptosis.

Laforge M, Campillo-Gimenez L, Monceaux V, Cumont MC, Hurtrel B, Corbeil J, Zaunders J, Elbim C, Estaquier J.

PLoS Pathog. 2011 Jun;7(6):e1002087. doi: 10.1371/journal.ppat.1002087. Epub 2011 Jun 23.

3.

AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection.

Campillo-Gimenez L, Cumont MC, Fay M, Kared H, Monceaux V, Diop O, Müller-Trutwin M, Hurtrel B, Lévy Y, Zaunders J, Dy M, Leite-de-Moraes MC, Elbim C, Estaquier J.

J Immunol. 2010 Jan 15;184(2):984-92. doi: 10.4049/jimmunol.0902316. Epub 2009 Dec 16.

4.

Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase.

Campillo-Gimenez L, Laforge M, Fay M, Brussel A, Cumont MC, Monceaux V, Diop O, Lévy Y, Hurtrel B, Zaunders J, Corbeil J, Elbim C, Estaquier J.

J Virol. 2010 Feb;84(4):1838-46. doi: 10.1128/JVI.01496-09. Epub 2009 Nov 25.

5.

Increased neutrophil apoptosis in chronically SIV-infected macaques.

Elbim C, Monceaux V, François S, Hurtrel B, Gougerot-Pocidalo MA, Estaquier J.

Retrovirology. 2009 Mar 24;6:29. doi: 10.1186/1742-4690-6-29.

6.

[Mesenteric lymph nodes, a sanctuary for the persistance of HIV. Escape mechanisms].

Estaquier J, Hurtrel B.

Med Sci (Paris). 2008 Dec;24(12):1055-60. doi: 10.1051/medsci/200824121055. French.

7.

Early divergence in neutrophil apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates.

Elbim C, Monceaux V, Mueller YM, Lewis MG, François S, Diop O, Akarid K, Hurtrel B, Gougerot-Pocidalo MA, Lévy Y, Katsikis PD, Estaquier J.

J Immunol. 2008 Dec 15;181(12):8613-23.

8.

Early divergence in lymphoid tissue apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates.

Cumont MC, Diop O, Vaslin B, Elbim C, Viollet L, Monceaux V, Lay S, Silvestri G, Le Grand R, Müller-Trutwin M, Hurtrel B, Estaquier J.

J Virol. 2008 Feb;82(3):1175-84. Epub 2007 Nov 21.

9.

CD4+ CCR5+ T-cell dynamics during simian immunodeficiency virus infection of Chinese rhesus macaques.

Monceaux V, Viollet L, Petit F, Cumont MC, Kaufmann GR, Aubertin AM, Hurtrel B, Silvestri G, Estaquier J.

J Virol. 2007 Dec;81(24):13865-75. Epub 2007 Sep 26.

10.
11.

Ex vivo characterization of human thymic dendritic cell subsets.

Schmitt N, Cumont MC, Nugeyre MT, Hurtrel B, Barré-Sinoussi F, Scott-Algara D, Israël N.

Immunobiology. 2007;212(3):167-77. Epub 2007 Mar 13.

PMID:
17412284
12.

HIV and the hidden face of the thymus.

Ho Tsong Fang R, Uittenbogaart CH, Hurtrel B.

AIDS. 2006 Nov 14;20(17):2240-2. No abstract available.

PMID:
17086070
13.

Death of CD4+ T cells from lymph nodes during primary SIVmac251 infection predicts the rate of AIDS progression.

Viollet L, Monceaux V, Petit F, Ho Tsong Fang R, Cumont MC, Hurtrel B, Estaquier J.

J Immunol. 2006 Nov 15;177(10):6685-94.

14.

IL-7 induces immunological improvement in SIV-infected rhesus macaques under antiviral therapy.

Beq S, Nugeyre MT, Ho Tsong Fang R, Gautier D, Legrand R, Schmitt N, Estaquier J, Barré-Sinoussi F, Hurtrel B, Cheynier R, Israël N.

J Immunol. 2006 Jan 15;176(2):914-22.

15.
16.

CD8+ T cell dynamics during primary simian immunodeficiency virus infection in macaques: relationship of effector cell differentiation with the extent of viral replication.

Monceaux V, Viollet L, Petit F, Ho Tsong Fang R, Cumont MC, Zaunders J, Hurtrel B, Estaquier J.

J Immunol. 2005 Jun 1;174(11):6898-908.

17.

Disease progression in macaques with low SIV replication levels: on the relevance of TREC counts.

Ho Tsong Fang R, Khatissian E, Monceaux V, Cumont MC, Beq S, Ameisen JC, Aubertin AM, Israël N, Estaquier J, Hurtrel B.

AIDS. 2005 Apr 29;19(7):663-73.

PMID:
15821392
18.

Apoptosis in SIV infection.

Hurtrel B, Petit F, Arnoult D, Müller-Trutwin M, Silvestri G, Estaquier J.

Cell Death Differ. 2005 Aug;12 Suppl 1:979-90. Review.

19.

HIV-1 clade promoters strongly influence spatial and temporal dynamics of viral replication in vivo.

Centlivre M, Sommer P, Michel M, Ho Tsong Fang R, Gofflo S, Valladeau J, Schmitt N, Thierry F, Hurtrel B, Wain-Hobson S, Sala M.

J Clin Invest. 2005 Feb;115(2):348-58.

20.

Tat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptides.

Belliard G, Hurtrel B, Moreau E, Lafont BA, Monceaux V, Roques B, Desgranges C, Aubertin AM, Le Grand R, Muller S.

Vaccine. 2005 Feb 3;23(11):1399-407.

PMID:
15661389
21.

Viral load in tissues during the early and chronic phase of non-pathogenic SIVagm infection.

Gueye A, Diop OM, Ploquin MJ, Kornfeld C, Faye A, Cumont MC, Hurtrel B, Barré-Sinoussi F, Müller-Trutwin MC.

J Med Primatol. 2004 Apr;33(2):83-97.

PMID:
15061721
22.

Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus.

Blancou P, Chenciner N, Ho Tsong Fang R, Monceaux V, Cumont MC, Guétard D, Hurtrel B, Wain-Hobson S.

J Virol. 2004 Feb;78(3):1080-92.

24.

Caspase-dependent and -independent T-cell death pathways in pathogenic simian immunodeficiency virus infection: relationship to disease progression.

Arnoult D, Petit F, Lelièvre JD, Lecossier D, Hance A, Monceaux V, Hurtrel B, Ho Tsong Fang R, Ameisen JC, Estaquier J.

Cell Death Differ. 2003 Nov;10(11):1240-52. Erratum in: Cell Death Differ. 2004 Jun;11(6):690. Lelièvie, JD [corrected to Lelièvre, JD]; Huntrel, B [corrected to Hurtrel, B].

25.

A molecularly cloned Schwarz strain of measles virus vaccine induces strong immune responses in macaques and transgenic mice.

Combredet C, Labrousse V, Mollet L, Lorin C, Delebecque F, Hurtrel B, McClure H, Feinberg MB, Brahic M, Tangy F.

J Virol. 2003 Nov;77(21):11546-54.

26.

IL-7 stimulates T cell renewal without increasing viral replication in simian immunodeficiency virus-infected macaques.

Nugeyre MT, Monceaux V, Beq S, Cumont MC, Ho Tsong Fang R, Chêne L, Morre M, Barré-Sinoussi F, Hurtrel B, Israël N.

J Immunol. 2003 Oct 15;171(8):4447-53.

27.
28.

Extensive apoptosis in lymphoid organs during primary SIV infection predicts rapid progression towards AIDS.

Monceaux V, Estaquier J, Février M, Cumont MC, Rivière Y, Aubertin AM, Ameisen JC, Hurtrel B.

AIDS. 2003 Jul 25;17(11):1585-96.

PMID:
12853740
29.

Simian immunodeficiency virus infection of CD4+CD8+ T cells in a macaque with an unusually high peripheral CD4+CD8+ T lymphocyte count.

Khatissian E, Monceaux V, Cumont MC, Ho Tsong Fang R, Estaquier J, Hurtrel B.

AIDS Res Hum Retroviruses. 2003 Apr;19(4):267-74.

PMID:
12804002
30.

Evaluation in rhesus macaques of Tat and rev-targeted immunization as a preventive vaccine against mucosal challenge with SHIV-BX08.

Verrier B, Le Grand R, Ataman-Onal Y, Terrat C, Guillon C, Durand PY, Hurtrel B, Aubertin AM, Sutter G, Erfle V, Girard M.

DNA Cell Biol. 2002 Sep;21(9):653-8.

PMID:
12396607
31.

Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.

Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D, Marmé F, Chérel Y, Salvetti A, Hurtrel B, Heard JM, Rivière Y, Moullier P.

J Virol. 2002 Nov;76(22):11605-11.

32.

DNA vaccine protection against challenge with simian/human immunodeficiency virus 89.6 in rhesus macaques.

Habel A, Chanel C, Le Grand R, Martinon F, Couillin L, Moog C, Doms R, Gauduin MC, Hurtrel B, Guillet JG, Aubertin AM, Girard M.

Dev Biol (Basel). 2000;104:101-5.

PMID:
11713807
33.

The infiltration kinetics of simian immunodeficiency virus-specific T cells drawn to sites of high antigenic stimulation determines local in vivo viral escape.

Blancou P, Chenciner N, Cumont MC, Wain-Hobson S, Hurtrel B, Cheynier R.

Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13237-42. Epub 2001 Oct 30.

34.

Persistence of pathogenic challenge virus in macaques protected by simian immunodeficiency virus SIVmacDeltanef.

Khatissian E, Monceaux V, Cumont MC, Kieny MP, Aubertin AM, Hurtrel B.

J Virol. 2001 Feb;75(3):1507-15.

35.

Early changes in peripheral blood T cells during primary infection of rhesus macaques with a pathogenic SIV.

Estaquier J, Monceaux V, Cumont MC, Aubertin AM, Hurtrel B, Ameisen JC.

J Med Primatol. 2000 Aug;29(3-4):127-35.

PMID:
11085574
36.

Progressive multifocal leukoencephalopathy and oligodendroglioma in a monkey co-infected by simian immunodeficiency virus and simian virus 40.

Chrétien F, Boche D, Lorin de la Grandmaison G, Ereau T, Mikol J, Hurtrel M, Hurtrel B, Gray F.

Acta Neuropathol. 2000 Sep;100(3):332-6.

PMID:
10965804
37.

Generation of CD8+ T cell-generated suppressor factor and beta-chemokines by targeted iliac lymph node immunization in rhesus monkeys challenged with SHIV-89.6P by the rectal route.

Aubertin AM, Le Grand R, Wang Y, Beyer C, Tao L, Neildez O, Barré-Sinoussi F, Hurtrel B, Moog C, Lehner T, Girard M.

AIDS Res Hum Retroviruses. 2000 Mar 1;16(4):381-92.

PMID:
10716376
38.

Implication of the C-terminal domain of nef protein in the reversion to pathogenicity of attenuated SIVmacBK28-41 in macaques.

Lafont BA, Rivière Y, Gloeckler L, Beyer C, Hurtrel B, Paule Kieny M, Kirn A, Aubertin AM.

Virology. 2000 Jan 20;266(2):286-98.

39.

Viral load and neuropathology in the SIV model.

Boche D, Khatissian E, Gray F, Falanga P, Montagnier L, Hurtrel B.

J Neurovirol. 1999 Jun;5(3):232-40.

PMID:
10414513
40.

Protection of SIVmac-infected macaque monkeys against superinfection by a simian immunodeficiency virus expressing envelope glycoproteins of HIV type 1.

Dunn CS, Hurtrel B, Beyer C, Gloeckler L, Ledger TN, Moog C, Kieny MP, Mehtali M, Schmitt D, Gut JP, Kirn A, Aubertin AM.

AIDS Res Hum Retroviruses. 1997 Jul 20;13(11):913-22.

PMID:
9223407
41.

[Contribution of animal models in the understanding of AIDS encephalopathy].

Boche D, Gray F, Khatissian E, Hurtrel M, Montagnier L, Hurtrel B.

Arch Anat Cytol Pathol. 1997;45(2-3):75-85. French.

PMID:
9382613
42.

Virus load and neuropathology in the FIV model.

Boche D, Hurtrel M, Gray F, Claessens-Maire MA, Ganière JP, Montagnier L, Hurtrel B.

J Neurovirol. 1996 Dec;2(6):377-87.

PMID:
8972419
43.

Interferon-gamma expression in macaque lymph nodes during primary infection with simian immunodeficiency virus.

Khatissian E, Monceaux V, Cumont MC, Montagnier L, Hurtrel B, Chakrabarti L.

Cytokine. 1996 Nov;8(11):844-52.

PMID:
9047081
44.

The relationship between the interferon alpha response and viral burden in primary SIV infection.

Khatissian E, Tovey MG, Cumont MC, Monceaux V, Lebon P, Montagnier L, Hurtrel B, Chakrabarti L.

AIDS Res Hum Retroviruses. 1996 Sep 1;12(13):1273-8.

PMID:
8870849
45.

Cytokine patterns and viral load in lymph nodes during the early stages of SIV infection.

Khatissian E, Chakrabarti L, Hurtrel B.

Res Virol. 1996 Mar-Jun;147(2-3):181-9.

PMID:
8901438
46.

Neuropathology of early HIV-1 infection.

Gray F, Scaravilli F, Everall I, Chretien F, An S, Boche D, Adle-Biassette H, Wingertsmann L, Durigon M, Hurtrel B, Chiodi F, Bell J, Lantos P.

Brain Pathol. 1996 Jan;6(1):1-15. Review.

PMID:
8866743
47.

Low susceptibility of resident microglia to simian immunodeficiency virus replication during the early stages of infection.

Boche D, Gray F, Chakrabarti L, Hurtrel M, Montagnier L, Hurtrel B.

Neuropathol Appl Neurobiol. 1995 Dec;21(6):535-9.

PMID:
8745243
48.

Limited viral spread and rapid immune response in lymph nodes of macaques inoculated with attenuated simian immunodeficiency virus.

Chakrabarti L, Baptiste V, Khatissian E, Cumont MC, Aubertin AM, Montagnier L, Hurtrel B.

Virology. 1995 Nov 10;213(2):535-48.

49.

Highly attenuated SIVmac142 is immunogenic but does not protect against SIVmac251 challenge.

Denesvre C, Le Grand R, Boissin-Cans F, Chakrabarti L, Hurtrel B, Vaslin B, Dormont D, Sonigo P.

AIDS Res Hum Retroviruses. 1995 Nov;11(11):1397-406.

PMID:
8573398
50.

Permissiveness of Kupffer cells for simian immunodeficiency virus (SIV) and morphological changes in the liver of rhesus monkeys at different periods of SIV infection.

Persidsky Y, Steffan AM, Gendrault JL, Hurtrel B, Berger S, Royer C, Stutte HJ, Muchmore E, Aubertin AM, Kirn A.

Hepatology. 1995 May;21(5):1215-25.

PMID:
7737626

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