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Items: 30

1.

Recurrent Rathke's Cleft Cysts: Incidence and Surgical Management in a Tertiary Pituitary Center over 2 Decades.

Wedemeyer MA, Lin M, Fredrickson VL, Arakelyan A, Bradley D, Donoho DA, Hurth KM, Weiss MH, Carmichael JD, Zada G.

Oper Neurosurg (Hagerstown). 2018 Sep 22. doi: 10.1093/ons/opy258. [Epub ahead of print]

PMID:
30247673
2.

The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease.

Neumann U, Ufer M, Jacobson LH, Rouzade-Dominguez ML, Huledal G, Kolly C, Lüönd RM, Machauer R, Veenstra SJ, Hurth K, Rueeger H, Tintelnot-Blomley M, Staufenbiel M, Shimshek DR, Perrot L, Frieauff W, Dubost V, Schiller H, Vogg B, Beltz K, Avrameas A, Kretz S, Pezous N, Rondeau JM, Beckmann N, Hartmann A, Vormfelde S, David OJ, Galli B, Ramos R, Graf A, Lopez Lopez C.

EMBO Mol Med. 2018 Sep 17. pii: e9316. doi: 10.15252/emmm.201809316. [Epub ahead of print]

3.

Ruptured Mycotic Aneurysm of the Distal Circulation in a Patient with Mucormycosis Without Direct Skull Base Extension: Case Report.

Rangwala SD, Strickland BA, Rennert RC, Ravina K, Bakhsheshian J, Hurth K, Giannotta SL, Russin JJ.

Oper Neurosurg (Hagerstown). 2018 May 24. doi: 10.1093/ons/opy127. [Epub ahead of print]

PMID:
29800469
4.

Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors.

Veenstra SJ, Rueeger H, Voegtle M, Lueoend R, Holzer P, Hurth K, Tintelnot-Blomley M, Frederiksen M, Rondeau JM, Jacobson L, Staufenbiel M, Neumann U, Machauer R.

Bioorg Med Chem Lett. 2018 Jul 1;28(12):2195-2200. doi: 10.1016/j.bmcl.2018.05.003. Epub 2018 May 3.

PMID:
29764741
5.

Quadruple Neoplasms following Radiation Therapy for Congenital Bilateral Retinoblastoma.

Szymanski LJ, Sibug Saber ME, Kim JW, Go JL, Zada G, Rao N, Hurth KM.

Ocul Oncol Pathol. 2017 Dec;4(1):33-37. doi: 10.1159/000477410. Epub 2017 Jul 6.

PMID:
29344496
6.

Variability and Lack of Prognostic Value Associated With Atypical Pituitary Adenoma Diagnosis: A Systematic Review and Critical Assessment of the Diagnostic Criteria.

Chesney K, Memel Z, Pangal DJ, Donoho D, Hurth K, Mathew A, Carmichael JD, Zada G.

Neurosurgery. 2018 Oct 1;83(4):602-610. doi: 10.1093/neuros/nyx541.

PMID:
29165661
7.

Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model.

Wang W, Cho HY, Rosenstein-Sisson R, Marín Ramos NI, Price R, Hurth K, Schönthal AH, Hofman FM, Chen TC.

J Neurosurg. 2018 Mar;128(3):695-700. doi: 10.3171/2016.11.JNS161212. Epub 2017 Apr 14.

PMID:
28409734
8.

Solitary Plasmacytoma in the Internal Auditory Canal and Cerebellopontine Angle Mimicking Meningioma.

Lavinsky J, Aaron KA, Christian E, Go JL, Hurth K, Giannotta SL, Friedman RA.

Otol Neurotol. 2016 Dec;37(10):e400-e401. No abstract available.

PMID:
26457817
9.

Congenital Acute Myeloid Leukemia with Unique Translocation t(11;19)(q23;p13.3).

Yarbrough CK, Bandt SK, Hurth K, Wambach JA, Rao R, Kulkarni S, White FV, Frater JL, Leonard JR.

Cureus. 2015 Jul 27;7(7):e289. doi: 10.7759/cureus.289. eCollection 2015 Jul.

10.

AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation.

Feuerbach D, Pezous N, Weiss M, Shakeri-Nejad K, Lingenhoehl K, Hoyer D, Hurth K, Bilbe G, Pryce CR, McAllister K, Chaperon F, Kucher K, Johns D, Blaettler T, Lopez Lopez C.

Br J Pharmacol. 2015 Mar;172(5):1292-304. doi: 10.1111/bph.13001. Epub 2015 Jan 12.

11.

A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease.

Armstrong RA, Kotzbauer PT, Perlmutter JS, Campbell MC, Hurth KM, Schmidt RE, Cairns NJ.

J Neural Transm (Vienna). 2014 Feb;121(2):171-81. doi: 10.1007/s00702-013-1084-z. Epub 2013 Aug 31.

12.

Whipple's disease masquerades as dementia with Lewy bodies.

Hurth K, Tarawneh R, Ghoshal N, Benzinger TLS, Clifford DB, Geschwind M, Morris JC, Galvin JE, Schmidt RE, Cairns NJ.

Alzheimer Dis Assoc Disord. 2015 Jan-Mar;29(1):85-89. doi: 10.1097/WAD.0b013e3182a715da. No abstract available.

13.

Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: a case report.

Funk RK, Ferraro DJ, Perrin RJ, Hurth KM, Stephens JJ, Mansur DB, Chicoine MR, Simpson JR, Jaboin JJ.

J Med Case Rep. 2012 Oct 8;6:341. doi: 10.1186/1752-1947-6-341.

14.

Acute presentation of tophaceous myelopathy.

Levin E, Hurth K, Joshi R, Brasington R.

J Rheumatol. 2011 Jul;38(7):1525-6. doi: 10.3899/jrheum.101335. No abstract available.

PMID:
21724731
15.

Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABAA receptor.

Hintermann S, Hurth K, Nozulak J, Tintelnot-Blomley M, Aichholz R, Blanz J, Kaupmann K, Mosbacher J.

Bioorg Med Chem Lett. 2011 Mar 1;21(5):1523-6. doi: 10.1016/j.bmcl.2010.12.107. Epub 2010 Dec 28.

PMID:
21277199
16.

Decahydroisoquinoline derivatives as novel non-peptidic, potent and subtype-selective somatostatin sst(3) receptor antagonists.

Troxler T, Hurth K, Schuh KH, Schoeffter P, Langenegger D, Enz A, Hoyer D.

Bioorg Med Chem Lett. 2010 Mar 1;20(5):1728-34. doi: 10.1016/j.bmcl.2010.01.063. Epub 2010 Jan 21.

PMID:
20137944
17.

Bronchial atresia.

Gipson MG, Cummings KW, Hurth KM.

Radiographics. 2009 Sep-Oct;29(5):1531-5. doi: 10.1148/rg.295085239. No abstract available.

PMID:
19755610
18.

Discovery of novel non-peptidic beta-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists.

Troxler T, Hurth K, Mattes H, Prashad M, Schoeffter P, Langenegger D, Enz A, Hoyer D.

Bioorg Med Chem Lett. 2009 Mar 1;19(5):1305-9. doi: 10.1016/j.bmcl.2009.01.072. Epub 2009 Jan 27.

PMID:
19208473
19.

Gamma-lactams--a novel scaffold for highly potent and selective alpha 7 nicotinic acetylcholine receptor agonists.

Enz A, Feuerbach D, Frederiksen MU, Gentsch C, Hurth K, Müller W, Nozulak J, Roy BL.

Bioorg Med Chem Lett. 2009 Mar 1;19(5):1287-91. doi: 10.1016/j.bmcl.2009.01.073. Epub 2009 Feb 7.

PMID:
19208472
20.

Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor.

Troxler T, Enz A, Hoyer D, Langenegger D, Neumann P, Pfäffli P, Schoeffter P, Hurth K.

Bioorg Med Chem Lett. 2008 Feb 1;18(3):979-82. Epub 2007 Dec 26.

PMID:
18162395
21.

SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists.

Hurth K, Enz A, Floersheim P, Gentsch C, Hoyer D, Langenegger D, Neumann P, Pfäffli P, Sorg D, Swoboda R, Vassout A, Troxler T.

Bioorg Med Chem Lett. 2007 Jul 15;17(14):3988-91. Epub 2007 Apr 30.

PMID:
17512199
22.

Identification and SAR of potent and selective non-peptide obeline somatostatin sst1 receptor antagonists.

Troxler T, Hoyer D, Langenegger D, Neumann P, Pfäffli P, Schoeffter P, Sorg D, Swoboda R, Hurth K.

Bioorg Med Chem Lett. 2007 Jul 15;17(14):3983-7. Epub 2007 Apr 29.

PMID:
17507221
23.

SRA880, in vitro characterization of the first non-peptide somatostatin sst(1) receptor antagonist.

Hoyer D, Nunn C, Hannon J, Schoeffter P, Feuerbach D, Schuepbach E, Langenegger D, Bouhelal R, Hurth K, Neumann P, Troxler T, Pfaeffli P.

Neurosci Lett. 2004 May 6;361(1-3):132-5.

PMID:
15135911
24.

Ligand-induced changes in estrogen receptor conformation as measured by site-directed spin labeling.

Hurth KM, Nilges MJ, Carlson KE, Tamrazi A, Belford RL, Katzenellenbogen JA.

Biochemistry. 2004 Feb 24;43(7):1891-907.

PMID:
14967030
25.

Agonist properties of putative small-molecule somatostatin sst2 receptor-selective antagonists.

Nunn C, Langenegger D, Hurth K, Schmidt K, Fehlmann D, Hoyer D.

Eur J Pharmacol. 2003 Apr 4;465(3):211-8.

PMID:
12681432
26.

Beta(2)/beta(3)-di- and alpha/beta(3)-tetrapeptide derivatives as potent agonists at somatostatin sst(4) receptors.

Nunn C, Rueping M, Langenegger D, Schuepbach E, Kimmerlin T, Micuch P, Hurth K, Seebach D, Hoyer D.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Feb;367(2):95-103. Epub 2003 Jan 24.

PMID:
12595949
27.

Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate.

Tamrazi A, Carlson KE, Daniels JR, Hurth KM, Katzenellenbogen JA.

Mol Endocrinol. 2002 Dec;16(12):2706-19.

PMID:
12456792
28.

NMR reporter screening for the detection of high-affinity ligands.

Jahnke W, Floersheim P, Ostermeier C, Zhang X, Hemmig R, Hurth K, Uzunov DP.

Angew Chem Int Ed Engl. 2002 Sep 16;41(18):3420-3. No abstract available.

PMID:
12298051
29.

Drug design at peptide receptors: somatostatin receptor ligands.

Hannon JP, Nunn C, Stolz B, Bruns C, Weckbecker G, Lewis I, Troxler T, Hurth K, Hoyer D.

J Mol Neurosci. 2002 Feb-Apr;18(1-2):15-27. Review.

PMID:
11931345
30.

Rapid HPLC screening method for contaminants found in implicated L-tryptophan associated with eosinophilia myalgia syndrome and adulterated rapeseed oil associated with toxic oil syndrome.

Williamson BL, Tomlinson AJ, Hurth KM, Posada de la Paz M, Gleich GJ, Naylor S.

Biomed Chromatogr. 1998 Sep-Oct;12(5):255-61.

PMID:
9787895

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