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Items: 1 to 20 of 54

1.

Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish.

Henderson F, Johnston HR, Badrock AP, Jones EA, Forster D, Nagaraju RT, Evangelou C, Kamarashev J, Green M, Fairclough M, Ramirez IB, He S, Snaar-Jagalska BE, Hollywood K, Dunn WB, Spaink HP, Smith MP, Lorigan P, Claude E, Williams KJ, McMahon AW, Hurlstone A.

Cancer Res. 2019 May 1;79(9):2136-2151. doi: 10.1158/0008-5472.CAN-18-2409. Epub 2019 Mar 12.

PMID:
30862716
2.

Novel contribution of epigenetic changes to nuclear dynamics.

Dreger M, Madrazo E, Hurlstone A, Redondo-Muñoz J.

Nucleus. 2019 Dec;10(1):42-47. doi: 10.1080/19491034.2019.1580100.

3.

Using zebrafish larval models to study brain injury, locomotor and neuroinflammatory outcomes following intracerebral haemorrhage.

Crilly S, Njegic A, Laurie SE, Fotiou E, Hudson G, Barrington J, Webb K, Young HL, Badrock AP, Hurlstone A, Rivers-Auty J, Parry-Jones AR, Allan SM, Kasher PR.

Version 2. F1000Res. 2018 Oct 8 [revised 2018 Jan 1];7:1617. doi: 10.12688/f1000research.16473.2. eCollection 2018.

4.

RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation.

Casar B, Badrock AP, Jiménez I, Arozarena I, Colón-Bolea P, Lorenzo-Martín LF, Barinaga-Rementería I, Barriuso J, Cappitelli V, Donoghue DJ, Bustelo XR, Hurlstone A, Crespo P.

Nat Commun. 2018 Sep 5;9(1):3595. doi: 10.1038/s41467-018-05941-8.

5.

WDR5 modulates cell motility and morphology and controls nuclear changes induced by a 3D environment.

Wang P, Dreger M, Madrazo E, Williams CJ, Samaniego R, Hodson NW, Monroy F, Baena E, Sánchez-Mateos P, Hurlstone A, Redondo-Muñoz J.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):8581-8586. doi: 10.1073/pnas.1719405115. Epub 2018 Jul 9.

6.

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.

Young HL, Rowling EJ, Bugatti M, Giurisato E, Luheshi N, Arozarena I, Acosta JC, Kamarashev J, Frederick DT, Cooper ZA, Reuben A, Gil J, Flaherty KT, Wargo JA, Vermi W, Smith MP, Wellbrock C, Hurlstone A.

J Exp Med. 2017 Jun 5;214(6):1691-1710. doi: 10.1084/jem.20160855. Epub 2017 Apr 27.

7.

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.

Diamantopoulou Z, White G, Fadlullah MZH, Dreger M, Pickering K, Maltas J, Ashton G, MacLeod R, Baillie GS, Kouskoff V, Lacaud G, Murray GI, Sansom OJ, Hurlstone AFL, Malliri A.

Cancer Cell. 2017 May 8;31(5):621-634.e6. doi: 10.1016/j.ccell.2017.03.007. Epub 2017 Apr 13.

8.

Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics.

Fernandez Del Ama L, Jones M, Walker P, Chapman A, Braun JA, Mohr J, Hurlstone AF.

Oncotarget. 2016 Jun 28;7(26):40348-40361. doi: 10.18632/oncotarget.9613.

9.

Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQQ209P-driven uveal melanomas in zebrafish.

Mouti MA, Dee C, Coupland SE, Hurlstone AF.

Oncotarget. 2016 Jun 28;7(26):39654-39670. doi: 10.18632/oncotarget.9207.

10.

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell-like Populations and Diverse Mononuclear Phagocytes.

Dee CT, Nagaraju RT, Athanasiadis EI, Gray C, Fernandez Del Ama L, Johnston SA, Secombes CJ, Cvejic A, Hurlstone AF.

J Immunol. 2016 Nov 1;197(9):3520-3530. Epub 2016 Sep 30.

11.

A hexIM1 on your melanocytes: transcription elongation - the Achilles' heel of melanoma?

Badrock A, Hurlstone A.

Pigment Cell Melanoma Res. 2016 Sep;29(5):496-7. doi: 10.1111/pcmr.12509. No abstract available.

PMID:
27399276
12.

Differentiation of THP1 Cells into Macrophages for Transwell Co-culture Assay with Melanoma Cells.

Smith MP, Young H, Hurlstone A, Wellbrock C.

Bio Protoc. 2015 May 11;5(21). pii: e1638.

13.

Correction: Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation.

Feng Y, Santoriello C, Mione M, Hurlstone A, Martin P.

PLoS Biol. 2016 Feb 11;14(2):e1002377. doi: 10.1371/journal.pbio.1002377. eCollection 2016 Feb. No abstract available.

14.

α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.

Paul NR, Allen JL, Chapman A, Morlan-Mairal M, Zindy E, Jacquemet G, Fernandez del Ama L, Ferizovic N, Green DM, Howe JD, Ehler E, Hurlstone A, Caswell PT.

J Cell Biol. 2015 Sep 14;210(6):1013-31. doi: 10.1083/jcb.201502040.

15.

Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes.

Herrero A, Pinto A, Colón-Bolea P, Casar B, Jones M, Agudo-Ibáñez L, Vidal R, Tenbaum SP, Nuciforo P, Valdizán EM, Horvath Z, Orfi L, Pineda-Lucena A, Bony E, Keri G, Rivas G, Pazos A, Gozalbes R, Palmer HG, Hurlstone A, Crespo P.

Cancer Cell. 2015 Aug 10;28(2):170-82. doi: 10.1016/j.ccell.2015.07.001.

16.

Zebrafish in oncology.

Barriuso J, Nagaraju R, Hurlstone A.

Aging (Albany NY). 2015 May;7(5):286-7. No abstract available.

17.

Zebrafish: a new companion for translational research in oncology.

Barriuso J, Nagaraju R, Hurlstone A.

Clin Cancer Res. 2015 Mar 1;21(5):969-75. doi: 10.1158/1078-0432.CCR-14-2921. Epub 2015 Jan 8. Review.

18.

HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.

Vaughan L, Tan CT, Chapman A, Nonaka D, Mack NA, Smith D, Booton R, Hurlstone AF, Malliri A.

Cell Rep. 2015 Jan 6;10(1):88-102. doi: 10.1016/j.celrep.2014.12.012. Epub 2014 Dec 24.

19.

TP53 in the UV spotlight: a bona fide driver of melanoma.

Hurlstone A, Wellbrock C.

Pigment Cell Melanoma Res. 2014 Nov;27(6):1010-1. doi: 10.1111/pcmr.12302. Epub 2014 Sep 2. No abstract available.

PMID:
25102761
20.

Heterogeneous tumor subpopulations cooperate to drive invasion.

Chapman A, Fernandez del Ama L, Ferguson J, Kamarashev J, Wellbrock C, Hurlstone A.

Cell Rep. 2014 Aug 7;8(3):688-95. doi: 10.1016/j.celrep.2014.06.045. Epub 2014 Jul 24.

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