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Items: 14

1.

Obstructive sleep apnea and cpap therapy alter distinct transcriptional programs in subcutaneous fat tissue.

Gharib SA, Hurley AL, Rosen MJ, Spilsbury JC, Schell AE, Mehra R, Patel SR.

Sleep. 2019 Dec 24. pii: zsz314. doi: 10.1093/sleep/zsz314. [Epub ahead of print]

PMID:
31872261
2.

Cross-linked cellulose nanocrystal aerogels as viable bone tissue scaffolds.

Osorio DA, Lee BEJ, Kwiecien JM, Wang X, Shahid I, Hurley AL, Cranston ED, Grandfield K.

Acta Biomater. 2019 Mar 15;87:152-165. doi: 10.1016/j.actbio.2019.01.049. Epub 2019 Jan 30.

PMID:
30710708
3.

Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder.

Di Salvo J, Nagabukuro H, Wickham LA, Abbadie C, DeMartino JA, Fitzmaurice A, Gichuru L, Kulick A, Donnelly MJ, Jochnowitz N, Hurley AL, Pereira A, Sanfiz A, Veronin G, Villa K, Woods J, Zamlynny B, Zycband E, Salituro GM, Frenkl T, Weber AE, Edmondson SD, Struthers M.

J Pharmacol Exp Ther. 2017 Feb;360(2):346-355. doi: 10.1124/jpet.116.237313. Epub 2016 Dec 13.

PMID:
27965369
4.

Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.

Edmondson SD, Zhu C, Kar NF, Di Salvo J, Nagabukuro H, Sacre-Salem B, Dingley K, Berger R, Goble SD, Morriello G, Harper B, Moyes CR, Shen DM, Wang L, Ball R, Fitzmaurice A, Frenkl T, Gichuru LN, Ha S, Hurley AL, Jochnowitz N, Levorse D, Mistry S, Miller RR, Ormes J, Salituro GM, Sanfiz A, Stevenson AS, Villa K, Zamlynny B, Green S, Struthers M, Weber AE.

J Med Chem. 2016 Jan 28;59(2):609-23. doi: 10.1021/acs.jmedchem.5b01372. Epub 2016 Jan 8.

PMID:
26709102
5.

Discovery of benzamides as potent human β3 adrenergic receptor agonists.

Zhu C, Kar NF, Li B, Costa M, Dingley KH, Di Salvo J, Ha SN, Hurley AL, Li X, Miller RR, Salituro GM, Struthers M, Weber AE, Hale JJ, Edmondson SD.

Bioorg Med Chem Lett. 2016 Jan 1;26(1):55-9. doi: 10.1016/j.bmcl.2015.11.030. Epub 2015 Nov 11.

PMID:
26590100
6.

Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder.

Moyes CR, Berger R, Goble SD, Harper B, Shen DM, Wang L, Bansal A, Brown PN, Chen AS, Dingley KH, Di Salvo J, Fitzmaurice A, Gichuru LN, Hurley AL, Jochnowitz N, Miller RR, Mistry S, Nagabukuro H, Salituro GM, Sanfiz A, Stevenson AS, Villa K, Zamlynny B, Struthers M, Weber AE, Edmondson SD.

J Med Chem. 2014 Feb 27;57(4):1437-53. doi: 10.1021/jm4017224. Epub 2014 Feb 5.

PMID:
24437735
7.

Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β3 adrenergic receptor agonists.

Morriello GJ, Wendt HR, Bansal A, Di Salvo J, Feighner S, He J, Hurley AL, Hreniuk DL, Salituro GM, Reddy MV, Galloway SM, McGettigan KK, Laws G, McKnight C, Doss GA, Tsou NN, Black RM, Morris J, Ball RG, Sanfiz AT, Streckfuss E, Struthers M, Edmondson SD.

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1865-70. doi: 10.1016/j.bmcl.2010.12.087. Epub 2010 Dec 25.

PMID:
21353541
8.

The Letter-Number Sequencing Test and its association with potential to work among people with psychotic illness.

Murtagh A, Hurley AL, Kinsella A, Corvin A, Donohoe G, Gill M, O'Callaghan E, Murphy KC.

Eur Psychiatry. 2010 Mar;25(2):101-4. doi: 10.1016/j.eurpsy.2009.06.004. Epub 2009 Aug 31.

PMID:
19720503
9.

Gene expression profiles during early differentiation of mouse embryonic stem cells.

Mansergh FC, Daly CS, Hurley AL, Wride MA, Hunter SM, Evans MJ.

BMC Dev Biol. 2009 Jan 9;9:5. doi: 10.1186/1471-213X-9-5.

10.

The construction of self in online support groups for victims of domestic violence.

Hurley AL, Sullivan P, McCarthy J.

Br J Soc Psychol. 2007 Dec;46(Pt 4):859-74.

PMID:
17535449
11.

Oxathiolene oxides: a novel family of compounds that induce ferritin, glutathione S-transferase, and other proteins of the phase II response.

Pietsch EC, Hurley AL, Scott EE, Duckworth BP, Welker ME, Leone-Kabler S, Townsend AJ, Torti FM, Torti SV.

Biochem Pharmacol. 2003 Apr 15;65(8):1261-9.

PMID:
12694867
12.
13.

Photoinduced DNA cleavage by cyclopentadienyl metal complexes conjugated to DNA recognition elements.

Hurley AL, Maddox MP 3rd, Scott TL, Flood MR, Mohler DL.

Org Lett. 2001 Aug 23;3(17):2761-4.

PMID:
11506628

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