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Detection of circulating extracellular mRNAs by modified small-RNA-sequencing analysis.

Akat KM, Lee YA, Hurley A, Morozov P, Max KE, Brown M, Bogardus K, Sopeyin A, Hildner K, Diacovo TG, Neurath MF, Borggrefe M, Tuschl T.

JCI Insight. 2019 Apr 11;5. pii: 127317. doi: 10.1172/jci.insight.127317.


Introducing THOR, a Model Microbiome for Genetic Dissection of Community Behavior.

Lozano GL, Bravo JI, Garavito Diago MF, Park HB, Hurley A, Peterson SB, Stabb EV, Crawford JM, Broderick NA, Handelsman J.

MBio. 2019 Mar 5;10(2). pii: e02846-18. doi: 10.1128/mBio.02846-18.


Cross-linked cellulose nanocrystal aerogels as viable bone tissue scaffolds.

Osorio DA, Lee BEJ, Kwiecien JM, Wang X, Shahid I, Hurley AL, Cranston ED, Grandfield K.

Acta Biomater. 2019 Mar 15;87:152-165. doi: 10.1016/j.actbio.2019.01.049. Epub 2019 Jan 30.


Gut microbiota density influences host physiology and is shaped by host and microbial factors.

Contijoch EJ, Britton GJ, Yang C, Mogno I, Li Z, Ng R, Llewellyn SR, Hira S, Johnson C, Rabinowitz KM, Barkan R, Dotan I, Hirten RP, Fu SC, Luo Y, Yang N, Luong T, Labrias PR, Lira S, Peter I, Grinspan A, Clemente JC, Kosoy R, Kim-Schulze S, Qin X, Castillo A, Hurley A, Atreja A, Rogers J, Fasihuddin F, Saliaj M, Nolan A, Reyes-Mercedes P, Rodriguez C, Aly S, Santa-Cruz K, Peters L, Suárez-Fariñas M, Huang R, Hao K, Zhu J, Zhang B, Losic B, Irizar H, Song WM, Di Narzo A, Wang W, Cohen BL, DiMaio C, Greenwald D, Itzkowitz S, Lucas A, Marion J, Maser E, Ungaro R, Naymagon S, Novak J, Shah B, Ullman T, Rubin P, George J, Legnani P, Telesco SE, Friedman JR, Brodmerkel C, Plevy S, Cho JH, Colombel JF, Schadt EE, Argmann C, Dubinsky M, Kasarskis A, Sands B, Faith JJ.

Elife. 2019 Jan 22;8. pii: e40553. doi: 10.7554/eLife.40553.


A Self-Deleting AAV-CRISPR System for In Vivo Genome Editing.

Li A, Lee CM, Hurley AE, Jarrett KE, De Giorgi M, Lu W, Balderrama KS, Doerfler AM, Deshmukh H, Ray A, Bao G, Lagor WR.

Mol Ther Methods Clin Dev. 2018 Dec 6;12:111-122. doi: 10.1016/j.omtm.2018.11.009. eCollection 2019 Mar 15.


Development and Validation of a Fall Prevention Knowledge Test.

Dykes PC, Bogaisky M, Carter EJ, Duckworth M, Hurley AC, Jackson EM, Khasnabish S, Lindros ME, Lipsitz SR, Scanlan M, Yu SP, Bates DW, Adelman JS.

J Am Geriatr Soc. 2019 Jan;67(1):133-138. doi: 10.1111/jgs.15563. Epub 2018 Oct 9.


Sport Preparticipation Screening for Asymptomatic Atlantoaxial Instability in Patients With Down Syndrome.

Tomlinson C, Campbell A, Hurley A, Fenton E, Heron N.

Clin J Sport Med. 2018 Aug 15. doi: 10.1097/JSM.0000000000000642. [Epub ahead of print]


Letter to the Editor: An Affront to Scientific Inquiry Re: Moore, D. R. (2018) Editorial: Auditory Processing Disorder, Ear Hear, 39, 617-620.

Iliadou VV, Chermak GD, Bamiou DE, Rawool VW, Ptok M, Purdy S, Jutras B, Moncrieff D, Stokkereit Mattsson T, Ferre JM, Fox C, Grech H, Geffner D, Hedjever M, Bellis TJ, Nimatoudis I, Eleftheriadis N, Pedersen ER, Weihing J, Guillory L, Madell JR, Hurley A, Whitelaw GM, Schochat E, Spyridakou C, Sidiras C, Thai-Van H, Kostopoulou A, Veuillet E, Keith B, Mountjoy A, Koohi N, Sirimanna T, Lau C, Cone B, Kiese-Himmel C, Abramson M, Raghunathrao R, Musiek FE.

Ear Hear. 2018 Nov/Dec;39(6):1236-1242. doi: 10.1097/AUD.0000000000000644. No abstract available.


Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research.

Jarrett KE, Lee C, De Giorgi M, Hurley A, Gillard BK, Doerfler AM, Li A, Pownall HJ, Bao G, Lagor WR.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):1997-2006. doi: 10.1161/ATVBAHA.118.311221.


CPAP Adherence Predictors in a Randomized Trial of Moderate-to-Severe OSA Enriched With Women and Minorities.

May AM, Gharibeh T, Wang L, Hurley A, Walia H, Strohl KP, Mehra R.

Chest. 2018 Sep;154(3):567-578. doi: 10.1016/j.chest.2018.04.010. Epub 2018 Apr 21.


Homology threading to generate RNA polymerase structures.

Kim Y, Benning N, Pham K, Baghdadi N, Caruso G, Colligan M, Grayson A, Hurley A, Ignatoski N, Mcclure S, Mckaig K, Neag E, Showers C, Tangalos A, Vanells J, Padmanabhan K, Burton ZF.

Protein Expr Purif. 2018 Jul;147:13-16. doi: 10.1016/j.pep.2018.02.002. Epub 2018 Feb 11. Review.


Delayed diagnosis of a patient with Usher syndrome 1C in a Louisiana Acadian family highlights the necessity of timely genetic testing for the diagnosis and management of congenital hearing loss.

Umrigar A, Musso A, Mercer D, Hurley A, Glausier C, Bakeer M, Marble M, Hicks C, Tsien F.

SAGE Open Med Case Rep. 2017 Dec 11;5:2050313X17745904. doi: 10.1177/2050313X17745904. eCollection 2017.


Characteristics of feed efficiency within and across lactation in dairy cows and the effect of genetic selection.

Hurley AM, Lopez-Villalobos N, McParland S, Lewis E, Kennedy E, O'Donovan M, Burke JL, Berry DP.

J Dairy Sci. 2018 Feb;101(2):1267-1280. doi: 10.3168/jds.2017-12841. Epub 2017 Nov 23.


Asymmetric regulation of quorum-sensing receptors drives autoinducer-specific gene expression programs in Vibrio cholerae.

Hurley A, Bassler BL.

PLoS Genet. 2017 May 26;13(5):e1006826. doi: 10.1371/journal.pgen.1006826. eCollection 2017 May.


Genetics of alternative definitions of feed efficiency in grazing lactating dairy cows.

Hurley AM, López-Villalobos N, McParland S, Lewis E, Kennedy E, O'Donovan M, Burke JL, Berry DP.

J Dairy Sci. 2017 Jul;100(7):5501-5514. doi: 10.3168/jds.2016-12314. Epub 2017 May 3.


Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.

Robbiani DF, Bozzacco L, Keeffe JR, Khouri R, Olsen PC, Gazumyan A, Schaefer-Babajew D, Avila-Rios S, Nogueira L, Patel R, Azzopardi SA, Uhl LFK, Saeed M, Sevilla-Reyes EE, Agudelo M, Yao KH, Golijanin J, Gristick HB, Lee YE, Hurley A, Caskey M, Pai J, Oliveira T, Wunder EA Jr, Sacramento G, Nery N Jr, Orge C, Costa F, Reis MG, Thomas NM, Eisenreich T, Weinberger DM, de Almeida ARP, West AP Jr, Rice CM, Bjorkman PJ, Reyes-Teran G, Ko AI, MacDonald MR, Nussenzweig MC.

Cell. 2017 May 4;169(4):597-609.e11. doi: 10.1016/j.cell.2017.04.024.


Validating Fall Prevention Icons to Support Patient-Centered Education.

Leung WY, Adelman J, Bates DW, Businger A, Dykes JS, Ergai A, Hurley A, Katsulis Z, Khorasani S, Scanlan M, Schenkel L, Rai A, Dykes PC.

J Patient Saf. 2017 Feb 22. doi: 10.1097/PTS.0000000000000354. [Epub ahead of print]


Investigation of piperazine benzamides as human β3 adrenergic receptor agonists for the treatment of overactive bladder.

Harper BH, Wang L, Zhu C, Kar NF, Li B, Moyes CR, Goble SD, Costa M, Dingley K, Di Salvo J, Ha SN, Hurley A, Li X, Miller RR, Nagabukuro H, Salituro GM, Smith S, Struthers M, Hale JJ, Edmondson SD, Berger R.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):1094-1098. doi: 10.1016/j.bmcl.2016.12.033. Epub 2016 Dec 11.


Detailed Audiological Evaluation of a Patient with Xeroderma Pigmentosum with Neural Degeneration.

Mercer D, Hurley A, Tsien F.

J Am Acad Audiol. 2017 Jan;28(1):80-90. doi: 10.3766/jaaa.15112.


Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder.

Di Salvo J, Nagabukuro H, Wickham LA, Abbadie C, DeMartino JA, Fitzmaurice A, Gichuru L, Kulick A, Donnelly MJ, Jochnowitz N, Hurley AL, Pereira A, Sanfiz A, Veronin G, Villa K, Woods J, Zamlynny B, Zycband E, Salituro GM, Frenkl T, Weber AE, Edmondson SD, Struthers M.

J Pharmacol Exp Ther. 2017 Feb;360(2):346-355. doi: 10.1124/jpet.116.237313. Epub 2016 Dec 13.


Nanocarriers from GRAS Zein Proteins to Encapsulate Hydrophobic Actives.

Weissmueller NT, Lu HD, Hurley A, Prud'homme RK.

Biomacromolecules. 2016 Nov 14;17(11):3828-3837. Epub 2016 Oct 31.


An Alternative Approach to Delivering Intensive Dialysis in Pregnancy.

Ross LE, Swift PA, Newbold SM, Bramham K, Hurley A, Gallagher H.

Perit Dial Int. 2016 9-10;36(5):575-7. doi: 10.3747/pdi.2016.00051. Review.


Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.

Boyaci H, Shah T, Hurley A, Kokona B, Li Z, Ventocilla C, Jeffrey PD, Semmelhack MF, Fairman R, Bassler BL, Hughson FM.

PLoS Biol. 2016 May 24;14(5):e1002464. doi: 10.1371/journal.pbio.1002464. eCollection 2016 May.


A New IVH Scoring System Based on Laterality Enhances Prediction of Neurodevelopmental Outcomes at 3 Years Age in Premature Infants.

Al-Mouqdad M, Al-Abdi S, Scott JN, Hurley A, Tang S, Creighton D, Mohammad K, Kamaluddeen M, Lodha A.

Am J Perinatol. 2017 Jan;34(1):44-50. doi: 10.1055/s-0036-1584138. Epub 2016 May 16.


Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.

Edmondson SD, Zhu C, Kar NF, Di Salvo J, Nagabukuro H, Sacre-Salem B, Dingley K, Berger R, Goble SD, Morriello G, Harper B, Moyes CR, Shen DM, Wang L, Ball R, Fitzmaurice A, Frenkl T, Gichuru LN, Ha S, Hurley AL, Jochnowitz N, Levorse D, Mistry S, Miller RR, Ormes J, Salituro GM, Sanfiz A, Stevenson AS, Villa K, Zamlynny B, Green S, Struthers M, Weber AE.

J Med Chem. 2016 Jan 28;59(2):609-23. doi: 10.1021/acs.jmedchem.5b01372. Epub 2016 Jan 8.


Dichotic listening training in children with autism spectrum disorder: A single subject design.

Denman I, Banajee M, Hurley A.

Int J Audiol. 2015;54(12):991-6. doi: 10.3109/14992027.2015.1070308. Epub 2015 Oct 8.


Discovery of benzamides as potent human β3 adrenergic receptor agonists.

Zhu C, Kar NF, Li B, Costa M, Dingley KH, Di Salvo J, Ha SN, Hurley AL, Li X, Miller RR, Salituro GM, Struthers M, Weber AE, Hale JJ, Edmondson SD.

Bioorg Med Chem Lett. 2016 Jan 1;26(1):55-9. doi: 10.1016/j.bmcl.2015.11.030. Epub 2015 Nov 11.


Inter-relationships among alternative definitions of feed efficiency in grazing lactating dairy cows.

Hurley AM, López-Villalobos N, McParland S, Kennedy E, Lewis E, O'Donovan M, Burke JL, Berry DP.

J Dairy Sci. 2016 Jan;99(1):468-79. doi: 10.3168/jds.2015-9928. Epub 2015 Nov 14.


Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers.

Anandasabapathy N, Breton G, Hurley A, Caskey M, Trumpfheller C, Sarma P, Pring J, Pack M, Buckley N, Matei I, Lyden D, Green J, Hawthorne T, Marsh HC, Yellin M, Davis T, Keler T, Schlesinger SJ.

Bone Marrow Transplant. 2015 Jul;50(7):924-30. doi: 10.1038/bmt.2015.74. Epub 2015 Apr 27.


Development and clinical validation of an in situ biopsy-based multimarker assay for risk stratification in prostate cancer.

Blume-Jensen P, Berman DM, Rimm DL, Shipitsin M, Putzi M, Nifong TP, Small C, Choudhury S, Capela T, Coupal L, Ernst C, Hurley A, Kaprelyants A, Chang H, Giladi E, Nardone J, Dunyak J, Loda M, Klein EA, Magi-Galluzzi C, Latour M, Epstein JI, Kantoff P, Saad F.

Clin Cancer Res. 2015 Jun 1;21(11):2591-600. doi: 10.1158/1078-0432.CCR-14-2603. Epub 2015 Mar 2.


Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles.

Lu HD, Spiegel AC, Hurley A, Perez LJ, Maisel K, Ensign LM, Hanes J, Bassler BL, Semmelhack MF, Prud'homme RK.

Nano Lett. 2015 Apr 8;15(4):2235-41. doi: 10.1021/acs.nanolett.5b00151. Epub 2015 Mar 3.


Evaluation of a web based tool to improve health behaviours in healthcare staff.

van Woerden HC, Ashton K, Garlick C, Hurley A, Cooper A, Willson A, Henry R, Kiparoglou V, Potter C.

Int Arch Med. 2014 Oct 8;7(1):44. doi: 10.1186/1755-7682-7-44. eCollection 2014.


Kommerell's diverticulum, right-sided aortic arch, and a hypoplastic left vertebral artery arising from the left common carotid artery.

Shaikh FM, Hurley A, Buckley O, Tierney S.

J Vasc Surg. 2014 Oct;60(4):1059. doi: 10.1016/j.jvs.2013.08.092. No abstract available.


Discovery of ML370, an inhibitor of Vibrio cholerae Quorum Sensing Acting via the LuxO response regulator.

Faloon P, Weiner WS, Matharu DS, Neuenswander B, Porubsky P, Youngsaye W, Bennion M, Ng WL, Hurley A, Mosher CM, Johnston S, Dandapani S, Schoenen FJ, Aubé J, Munoz B, Palmer M, Bassler BL, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 12 [updated 2014 Sep 18].


Discovery of ML366, an inhibitor of Vibrio cholerae Quorum Sensing Acting via the LuxO response regulator.

Faloon P, Jewett I, Youngsaye W, Bennion M, Ng WL, Hurley A, Lewis TA, Edwankar RV, Le H, Mosher CM, Johnston S, Dandapani S, Munoz B, Palmer M, Bassler BL, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 12 [updated 2014 Sep 18].


Use of synthetic urine as a matrix substitute for standard and quality control materials in the clinical assessment of iodine by inductively coupled plasma mass spectrometry.

Haglock-Adler CJ, Hurley A, Strathmann FG.

Clin Biochem. 2014 Oct;47(15):80-2. doi: 10.1016/j.clinbiochem.2014.07.008. Epub 2014 Jul 17.


Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error.

Shipitsin M, Small C, Choudhury S, Giladi E, Friedlander S, Nardone J, Hussain S, Hurley AD, Ernst C, Huang YE, Chang H, Nifong TP, Rimm DL, Dunyak J, Loda M, Berman DM, Blume-Jensen P.

Br J Cancer. 2014 Sep 9;111(6):1201-12. doi: 10.1038/bjc.2014.396. Epub 2014 Jul 17.


A patient-centered longitudinal care plan: vision versus reality.

Dykes PC, Samal L, Donahue M, Greenberg JO, Hurley AC, Hasan O, O'Malley TA, Venkatesh AK, Volk LA, Bates DW.

J Am Med Inform Assoc. 2014 Nov-Dec;21(6):1082-90. doi: 10.1136/amiajnl-2013-002454. Epub 2014 Jul 4.


What is discomfort in persons with dementia who are agitated?

Volicer L, Hurley AC.

JAMA Intern Med. 2014 Feb 1;174(2):297. doi: 10.1001/jamainternmed.2013.11997. No abstract available.


Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder.

Moyes CR, Berger R, Goble SD, Harper B, Shen DM, Wang L, Bansal A, Brown PN, Chen AS, Dingley KH, Di Salvo J, Fitzmaurice A, Gichuru LN, Hurley AL, Jochnowitz N, Miller RR, Mistry S, Nagabukuro H, Salituro GM, Sanfiz A, Stevenson AS, Villa K, Zamlynny B, Struthers M, Weber AE, Edmondson SD.

J Med Chem. 2014 Feb 27;57(4):1437-53. doi: 10.1021/jm4017224. Epub 2014 Feb 5.


Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae.

Perez LJ, Karagounis TK, Hurley A, Bassler BL, Semmelhack MF.

Chem Sci. 2014 Jan 1;5(1):151-155.


The Rockefeller University Navigation Program: a structured multidisciplinary protocol development and educational program to advance translational research.

Brassil D, Kost RG, Dowd KA, Hurley AM, Rainer TL, Coller BS.

Clin Transl Sci. 2014 Feb;7(1):12-9. doi: 10.1111/cts.12134. Epub 2014 Jan 9.


Glial cell line-derived neurotrophic factor-secreting human neural progenitors show long-term survival, maturation into astrocytes, and no tumor formation following transplantation into the spinal cord of immunocompromised rats.

Gowing G, Shelley B, Staggenborg K, Hurley A, Avalos P, Victoroff J, Latter J, Garcia L, Svendsen CN.

Neuroreport. 2014 Apr 16;25(6):367-72. doi: 10.1097/WNR.0000000000000092.


Discovery of Two, Structurally Distinct Agonists of Vibrio cholerae Quorum Sensing Acting via the CqsS Membrane Receptor.

Faloon P, Youngsaye W, Bennion M, Ng WL, Hurley A, Lewis TA, Edwankar RV, Yao E, Pu J, Nag PP, Wurst JM, Bennion M, Le H, Mosher CM, Johnston S, Dandapani S, Munoz B, Palmer M, Bassler BL, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 14 [updated 2013 Sep 3].


Primary Immune Deficiency Treatment Consortium (PIDTC) report.

Griffith LM, Cowan MJ, Notarangelo LD, Kohn DB, Puck JM, Pai SY, Ballard B, Bauer SC, Bleesing JJ, Boyle M, Brower A, Buckley RH, van der Burg M, Burroughs LM, Candotti F, Cant AJ, Chatila T, Cunningham-Rundles C, Dinauer MC, Dvorak CC, Filipovich AH, Fleisher TA, Bobby Gaspar H, Gungor T, Haddad E, Hovermale E, Huang F, Hurley A, Hurley M, Iyengar S, Kang EM, Logan BR, Long-Boyle JR, Malech HL, McGhee SA, Modell F, Modell V, Ochs HD, O'Reilly RJ, Parkman R, Rawlings DJ, Routes JM, Shearer WT, Small TN, Smith H, Sullivan KE, Szabolcs P, Thrasher A, Torgerson TR, Veys P, Weinberg K, Zuniga-Pflucker JC; workshop participants.

J Allergy Clin Immunol. 2014 Feb;133(2):335-47. doi: 10.1016/j.jaci.2013.07.052. Epub 2013 Oct 15.


Content and functional specifications for a standards-based multidisciplinary rounding tool to maintain continuity across acute and critical care.

Collins S, Hurley AC, Chang FY, Illa AR, Benoit A, Laperle S, Dykes PC.

J Am Med Inform Assoc. 2014 May-Jun;21(3):438-47. doi: 10.1136/amiajnl-2013-001949. Epub 2013 Sep 30.


Skull asymmetry as an unusual presentation of an intracranial tumour.

Boyle M, Hurley A, Curtis E.

Pediatr Neurosurg. 2012;48(5):333-4. doi: 10.1159/000351548. Epub 2013 Jun 25. No abstract available.


Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, Frederick DT, Hurley AD, Nellore A, Kung AL, Wargo JA, Song JS, Fisher DE, Arany Z, Widlund HR.

Cancer Cell. 2013 Mar 18;23(3):302-15. doi: 10.1016/j.ccr.2013.02.003. Epub 2013 Mar 7.


EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs.

Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN.

Stem Cell Res. 2013 May;10(3):417-427. doi: 10.1016/j.scr.2013.01.009. Epub 2013 Feb 4.


Building and testing a patient-centric electronic bedside communication center.

Dykes PC, Carroll DL, Hurley AC, Benoit A, Chang F, Pozzar R, Caligtan CA.

J Gerontol Nurs. 2013 Jan;39(1):15-9. doi: 10.3928/00989134-20121204-03. Epub 2012 Dec 13.


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