Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 106

1.

Methodological consensus on clinical proton MRS of the brain: Review and recommendations.

Wilson M, Andronesi O, Barker PB, Bartha R, Bizzi A, Bolan PJ, Brindle KM, Choi IY, Cudalbu C, Dydak U, Emir UE, Gonzalez RG, Gruber S, Gruetter R, Gupta RK, Heerschap A, Henning A, Hetherington HP, Huppi PS, Hurd RE, Kantarci K, Kauppinen RA, Klomp DWJ, Kreis R, Kruiskamp MJ, Leach MO, Lin AP, Luijten PR, Marjańska M, Maudsley AA, Meyerhoff DJ, Mountford CE, Mullins PG, Murdoch JB, Nelson SJ, Noeske R, Öz G, Pan JW, Peet AC, Poptani H, Posse S, Ratai EM, Salibi N, Scheenen TWJ, Smith ICP, Soher BJ, Tkáč I, Vigneron DB, Howe FA.

Magn Reson Med. 2019 Aug;82(2):527-550. doi: 10.1002/mrm.27742. Epub 2019 Mar 28. Review.

2.

Dynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization.

Brender JR, Kishimoto S, Merkle H, Reed G, Hurd RE, Chen AP, Ardenkjaer-Larsen JH, Munasinghe J, Saito K, Seki T, Oshima N, Yamamoto K, Choyke PL, Mitchell J, Krishna MC.

Sci Rep. 2019 Mar 4;9(1):3410. doi: 10.1038/s41598-019-38981-1.

3.

Pulse sequence considerations for quantification of pyruvate-to-lactate conversion kPL in hyperpolarized 13 C imaging.

Chen HY, Gordon JW, Bok RA, Cao P, von Morze C, van Criekinge M, Milshteyn E, Carvajal L, Hurd RE, Kurhanewicz J, Vigneron DB, Larson PEZ.

NMR Biomed. 2019 Mar;32(3):e4052. doi: 10.1002/nbm.4052. Epub 2019 Jan 21.

PMID:
30664305
4.

PKM2 activation sensitizes cancer cells to growth inhibition by 2-deoxy-D-glucose.

Tee SS, Park JM, Hurd RE, Brimacombe KR, Boxer MB, Massoud TF, Rutt BK, Spielman DM.

Oncotarget. 2017 Jul 26;8(53):90959-90968. doi: 10.18632/oncotarget.19630. eCollection 2017 Oct 31.

5.

In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1-13 C]Alanine.

Park JM, Khemtong C, Liu SC, Hurd RE, Spielman DM.

Magn Reson Med. 2017 May;77(5):1741-1748. doi: 10.1002/mrm.26662. Epub 2017 Mar 5.

6.

Hyperpolarized (13)C-lactate to (13)C-bicarbonate ratio as a biomarker for monitoring the acute response of anti-vascular endothelial growth factor (anti-VEGF) treatment.

Park JM, Spielman DM, Josan S, Jang T, Merchant M, Hurd RE, Mayer D, Recht LD.

NMR Biomed. 2016 May;29(5):650-9. doi: 10.1002/nbm.3509. Epub 2016 Mar 14.

7.

Hyperpolarized 13C NMR observation of lactate kinetics in skeletal muscle.

Park JM, Josan S, Mayer D, Hurd RE, Chung Y, Bendahan D, Spielman DM, Jue T.

J Exp Biol. 2015 Oct;218(Pt 20):3308-18. doi: 10.1242/jeb.123141. Epub 2015 Sep 7.

8.

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia.

Maddox DM, Collin GB, Ikeda A, Pratt CH, Ikeda S, Johnson BA, Hurd RE, Shopland LS, Naggert JK, Chang B, Krebs MP, Nishina PM.

Invest Ophthalmol Vis Sci. 2015 Jun;56(6):3776-87. doi: 10.1167/iovs.14-16047.

9.

Volumetric spiral chemical shift imaging of hyperpolarized [2-(13) c]pyruvate in a rat c6 glioma model.

Park JM, Josan S, Jang T, Merchant M, Watkins R, Hurd RE, Recht LD, Mayer D, Spielman DM.

Magn Reson Med. 2016 Mar;75(3):973-84. doi: 10.1002/mrm.25766. Epub 2015 May 6.

10.

Handheld electromagnet carrier for transfer of hyperpolarized carbon-13 samples.

Shang H, Skloss T, von Morze C, Carvajal L, Van Criekinge M, Milshteyn E, Larson PE, Hurd RE, Vigneron DB.

Magn Reson Med. 2016 Feb;75(2):917-22. doi: 10.1002/mrm.25657. Epub 2015 Mar 11.

11.

Clinical proton MR spectroscopy in central nervous system disorders.

Oz G, Alger JR, Barker PB, Bartha R, Bizzi A, Boesch C, Bolan PJ, Brindle KM, Cudalbu C, Dinçer A, Dydak U, Emir UE, Frahm J, González RG, Gruber S, Gruetter R, Gupta RK, Heerschap A, Henning A, Hetherington HP, Howe FA, Hüppi PS, Hurd RE, Kantarci K, Klomp DW, Kreis R, Kruiskamp MJ, Leach MO, Lin AP, Luijten PR, Marjańska M, Maudsley AA, Meyerhoff DJ, Mountford CE, Nelson SJ, Pamir MN, Pan JW, Peet AC, Poptani H, Posse S, Pouwels PJ, Ratai EM, Ross BD, Scheenen TW, Schuster C, Smith IC, Soher BJ, Tkáč I, Vigneron DB, Kauppinen RA; MRS Consensus Group.

Radiology. 2014 Mar;270(3):658-79. doi: 10.1148/radiol.13130531. Review.

12.

Frequency correction method for improved spatial correlation of hyperpolarized 13C metabolites and anatomy.

Cunningham CH, Dominguez Viqueira W, Hurd RE, Chen AP.

NMR Biomed. 2014 Feb;27(2):212-8. doi: 10.1002/nbm.3055. Epub 2013 Dec 19.

PMID:
24353129
13.

Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate.

Nelson SJ, Kurhanewicz J, Vigneron DB, Larson PE, Harzstark AL, Ferrone M, van Criekinge M, Chang JW, Bok R, Park I, Reed G, Carvajal L, Small EJ, Munster P, Weinberg VK, Ardenkjaer-Larsen JH, Chen AP, Hurd RE, Odegardstuen LI, Robb FJ, Tropp J, Murray JA.

Sci Transl Med. 2013 Aug 14;5(198):198ra108. doi: 10.1126/scitranslmed.3006070.

14.

Measuring mitochondrial metabolism in rat brain in vivo using MR Spectroscopy of hyperpolarized [2-¹³C]pyruvate.

Park JM, Josan S, Grafendorfer T, Yen YF, Hurd RE, Spielman DM, Mayer D.

NMR Biomed. 2013 Oct;26(10):1197-203. doi: 10.1002/nbm.2935. Epub 2013 Apr 2.

15.

Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized (13)C magnetic resonance spectroscopic imaging.

Park JM, Recht LD, Josan S, Merchant M, Jang T, Yen YF, Hurd RE, Spielman DM, Mayer D.

Neuro Oncol. 2013 Apr;15(4):433-41. doi: 10.1093/neuonc/nos319. Epub 2013 Jan 17.

16.

Perfusion and diffusion sensitive 13C stimulated-echo MRSI for metabolic imaging of cancer.

Larson PE, Hurd RE, Kerr AB, Pauly JM, Bok RA, Kurhanewicz J, Vigneron DB.

Magn Reson Imaging. 2013 Jun;31(5):635-42. doi: 10.1016/j.mri.2012.10.020. Epub 2012 Dec 21.

17.

Exchange-linked dissolution agents in dissolution-DNP (13)C metabolic imaging.

Hurd RE, Spielman D, Josan S, Yen YF, Pfefferbaum A, Mayer D.

Magn Reson Med. 2013 Oct;70(4):936-42. doi: 10.1002/mrm.24544. Epub 2012 Nov 19.

18.

Hyperpolarized 13C metabolic imaging using dissolution dynamic nuclear polarization.

Hurd RE, Yen YF, Chen A, Ardenkjaer-Larsen JH.

J Magn Reson Imaging. 2012 Dec;36(6):1314-28. doi: 10.1002/jmri.23753. Review.

PMID:
23165733
19.

Metabolite kinetics in C6 rat glioma model using magnetic resonance spectroscopic imaging of hyperpolarized [1-(13)C]pyruvate.

Park JM, Josan S, Jang T, Merchant M, Yen YF, Hurd RE, Recht L, Spielman DM, Mayer D.

Magn Reson Med. 2012 Dec;68(6):1886-93. doi: 10.1002/mrm.24181. Epub 2012 Feb 14.

20.

Application of hyperpolarized [1-¹³C]lactate for the in vivo investigation of cardiac metabolism.

Mayer D, Yen YF, Josan S, Park JM, Pfefferbaum A, Hurd RE, Spielman DM.

NMR Biomed. 2012 Oct;25(10):1119-24. doi: 10.1002/nbm.2778. Epub 2012 Jan 25.

21.

Gradient-enhanced spectroscopy. 1990.

Hurd RE.

J Magn Reson. 2011 Dec;213(2):467-73. doi: 10.1016/j.jmr.2011.09.005. No abstract available.

PMID:
22152363
22.

Spin tagging for hyperpolarized ¹³C metabolic studies.

Chen AP, Hurd RE, Cunningham CH.

J Magn Reson. 2012 Jan;214(1):319-23. doi: 10.1016/j.jmr.2011.10.007. Epub 2011 Oct 19.

PMID:
22050921
23.

Generating super stimulated-echoes in MRI and their application to hyperpolarized C-13 diffusion metabolic imaging.

Larson PE, Kerr AB, Reed GD, Hurd RE, Kurhanewicz J, Pauly JM, Vigneron DB.

IEEE Trans Med Imaging. 2012 Feb;31(2):265-75. doi: 10.1109/TMI.2011.2168235. Epub 2011 Oct 21.

24.

Gradient enhanced spectroscopy.

van Zijl PC, Hurd RE.

J Magn Reson. 2011 Dec;213(2):474-6. doi: 10.1016/j.jmr.2011.08.018. Epub 2011 Sep 8.

PMID:
21906981
25.

Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo.

Chen AP, Hurd RE, Schroeder MA, Lau AZ, Gu YP, Lam WW, Barry J, Tropp J, Cunningham CH.

NMR Biomed. 2012 Feb;25(2):305-11. doi: 10.1002/nbm.1749. Epub 2011 Jul 19.

26.

Spectral-spatial excitation for rapid imaging of DNP compounds.

Lau AZ, Chen AP, Hurd RE, Cunningham CH.

NMR Biomed. 2011 Oct;24(8):988-96. doi: 10.1002/nbm.1743. Epub 2011 Jul 12.

PMID:
21751271
27.

(13)C MR reporter probe system using dynamic nuclear polarization.

Chen AP, Hurd RE, Gu YP, Wilson DM, Cunningham CH.

NMR Biomed. 2011 Jun;24(5):514-20. doi: 10.1002/nbm.1618. Epub 2010 Dec 8.

PMID:
21674653
28.

In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma.

Darpolor MM, Yen YF, Chua MS, Xing L, Clarke-Katzenberg RH, Shi W, Mayer D, Josan S, Hurd RE, Pfefferbaum A, Senadheera L, So S, Hofmann LV, Glazer GM, Spielman DM.

NMR Biomed. 2011 Jun;24(5):506-13. doi: 10.1002/nbm.1616. Epub 2010 Dec 12.

29.

Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice.

Boldt K, Mans DA, Won J, van Reeuwijk J, Vogt A, Kinkl N, Letteboer SJ, Hicks WL, Hurd RE, Naggert JK, Texier Y, den Hollander AI, Koenekoop RK, Bennett J, Cremers FP, Gloeckner CJ, Nishina PM, Roepman R, Ueffing M.

J Clin Invest. 2011 Jun;121(6):2169-80. doi: 10.1172/JCI45627. Epub 2011 May 23.

30.

Dynamic and high-resolution metabolic imaging of hyperpolarized [1-13C]-pyruvate in the rat brain using a high-performance gradient insert.

Mayer D, Yen YF, Takahashi A, Josan S, Tropp J, Rutt BK, Hurd RE, Spielman DM, Pfefferbaum A.

Magn Reson Med. 2011 May;65(5):1228-33. doi: 10.1002/mrm.22707. Epub 2010 Nov 30.

31.

Detection of inflammatory arthritis by using hyperpolarized 13C-pyruvate with MR imaging and spectroscopy.

MacKenzie JD, Yen YF, Mayer D, Tropp JS, Hurd RE, Spielman DM.

Radiology. 2011 May;259(2):414-20. doi: 10.1148/radiol.10101921. Epub 2011 Mar 15.

32.

Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice.

Friedman JS, Chang B, Krauth DS, Lopez I, Waseem NH, Hurd RE, Feathers KL, Branham KE, Shaw M, Thomas GE, Brooks MJ, Liu C, Bakeri HA, Campos MM, Maubaret C, Webster AR, Rodriguez IR, Thompson DA, Bhattacharya SS, Koenekoop RK, Heckenlively JR, Swaroop A.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15523-8. doi: 10.1073/pnas.1002897107. Epub 2010 Aug 16.

33.

Cerebral dynamics and metabolism of hyperpolarized [1-(13)C]pyruvate using time-resolved MR spectroscopic imaging.

Hurd RE, Yen YF, Tropp J, Pfefferbaum A, Spielman DM, Mayer D.

J Cereb Blood Flow Metab. 2010 Oct;30(10):1734-41. doi: 10.1038/jcbfm.2010.93. Epub 2010 Jun 30.

34.

Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate.

Hurd RE, Yen YF, Mayer D, Chen A, Wilson D, Kohler S, Bok R, Vigneron D, Kurhanewicz J, Tropp J, Spielman D, Pfefferbaum A.

Magn Reson Med. 2010 May;63(5):1137-43. doi: 10.1002/mrm.22364.

35.

In vivo application of sub-second spiral chemical shift imaging (CSI) to hyperpolarized 13C metabolic imaging: comparison with phase-encoded CSI.

Mayer D, Yen YF, Levin YS, Tropp J, Pfefferbaum A, Hurd RE, Spielman DM.

J Magn Reson. 2010 Jun;204(2):340-5. doi: 10.1016/j.jmr.2010.03.005. Epub 2010 Mar 9.

36.

The mouse model of Down syndrome Ts65Dn presents visual deficits as assessed by pattern visual evoked potentials.

Scott-McKean JJ, Chang B, Hurd RE, Nusinowitz S, Schmidt C, Davisson MT, Costa AC.

Invest Ophthalmol Vis Sci. 2010 Jun;51(6):3300-8. doi: 10.1167/iovs.09-4465. Epub 2010 Feb 3.

37.

Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice.

Zierhut ML, Yen YF, Chen AP, Bok R, Albers MJ, Zhang V, Tropp J, Park I, Vigneron DB, Kurhanewicz J, Hurd RE, Nelson SJ.

J Magn Reson. 2010 Jan;202(1):85-92. doi: 10.1016/j.jmr.2009.10.003. Epub 2009 Oct 13.

38.

Design of spectral-spatial outer volume suppression RF pulses for tissue specific metabolic characterization with hyperpolarized 13C pyruvate.

Chen AP, Leung K, Lam W, Hurd RE, Vigneron DB, Cunningham CH.

J Magn Reson. 2009 Oct;200(2):344-8. doi: 10.1016/j.jmr.2009.06.021. Epub 2009 Jul 3.

39.

Application of subsecond spiral chemical shift imaging to real-time multislice metabolic imaging of the rat in vivo after injection of hyperpolarized 13C1-pyruvate.

Mayer D, Yen YF, Tropp J, Pfefferbaum A, Hurd RE, Spielman DM.

Magn Reson Med. 2009 Sep;62(3):557-64. doi: 10.1002/mrm.22041.

40.

In vivo measurement of ethanol metabolism in the rat liver using magnetic resonance spectroscopy of hyperpolarized [1-13C]pyruvate.

Spielman DM, Mayer D, Yen YF, Tropp J, Hurd RE, Pfefferbaum A.

Magn Reson Med. 2009 Aug;62(2):307-13. doi: 10.1002/mrm.21998.

41.

In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate.

Hu S, Chen AP, Zierhut ML, Bok R, Yen YF, Schroeder MA, Hurd RE, Nelson SJ, Kurhanewicz J, Vigneron DB.

Mol Imaging Biol. 2009 Nov-Dec;11(6):399-407. doi: 10.1007/s11307-009-0218-z. Epub 2009 May 8.

42.

Imaging considerations for in vivo 13C metabolic mapping using hyperpolarized 13C-pyruvate.

Yen YF, Kohler SJ, Chen AP, Tropp J, Bok R, Wolber J, Albers MJ, Gram KA, Zierhut ML, Park I, Zhang V, Hu S, Nelson SJ, Vigneron DB, Kurhanewicz J, Dirven HA, Hurd RE.

Magn Reson Med. 2009 Jul;62(1):1-10. doi: 10.1002/mrm.21987.

43.

Generation of hyperpolarized substrates by secondary labeling with [1,1-13C] acetic anhydride.

Wilson DM, Hurd RE, Keshari K, Van Criekinge M, Chen AP, Nelson SJ, Vigneron DB, Kurhanewicz J.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5503-7. doi: 10.1073/pnas.0810190106. Epub 2009 Mar 10.

44.

In vivo hyperpolarized 13C MR spectroscopic imaging with 1H decoupling.

Chen AP, Tropp J, Hurd RE, Van Criekinge M, Carvajal LG, Xu D, Kurhanewicz J, Vigneron DB.

J Magn Reson. 2009 Mar;197(1):100-6. doi: 10.1016/j.jmr.2008.12.004. Epub 2008 Dec 13.

45.

Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.

Albers MJ, Bok R, Chen AP, Cunningham CH, Zierhut ML, Zhang VY, Kohler SJ, Tropp J, Hurd RE, Yen YF, Nelson SJ, Vigneron DB, Kurhanewicz J.

Cancer Res. 2008 Oct 15;68(20):8607-15. doi: 10.1158/0008-5472.CAN-08-0749.

46.

Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene.

Chang B, Mandal MN, Chavali VR, Hawes NL, Khan NW, Hurd RE, Smith RS, Davisson ML, Kopplin L, Klein BE, Klein R, Iyengar SK, Heckenlively JR, Ayyagari R.

Hum Mol Genet. 2008 Dec 15;17(24):3929-41. doi: 10.1093/hmg/ddn295. Epub 2008 Sep 18.

47.

Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies.

Chen AP, Kurhanewicz J, Bok R, Xu D, Joun D, Zhang V, Nelson SJ, Hurd RE, Vigneron DB.

Magn Reson Imaging. 2008 Jul;26(6):721-6. doi: 10.1016/j.mri.2008.01.002. Epub 2008 May 13.

48.

Pulse sequence for dynamic volumetric imaging of hyperpolarized metabolic products.

Cunningham CH, Chen AP, Lustig M, Hargreaves BA, Lupo J, Xu D, Kurhanewicz J, Hurd RE, Pauly JM, Nelson SJ, Vigneron DB.

J Magn Reson. 2008 Jul;193(1):139-46. doi: 10.1016/j.jmr.2008.03.012. Epub 2008 Mar 23.

49.

Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T-initial experience.

Chen AP, Albers MJ, Cunningham CH, Kohler SJ, Yen YF, Hurd RE, Tropp J, Bok R, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB.

Magn Reson Med. 2007 Dec;58(6):1099-106.

50.

In vivo 13 carbon metabolic imaging at 3T with hyperpolarized 13C-1-pyruvate.

Kohler SJ, Yen Y, Wolber J, Chen AP, Albers MJ, Bok R, Zhang V, Tropp J, Nelson S, Vigneron DB, Kurhanewicz J, Hurd RE.

Magn Reson Med. 2007 Jul;58(1):65-9.

Supplemental Content

Support Center