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Items: 1 to 50 of 183

1.

Polymeric mesh and insulin-like growth factor 1 delivery enhance cell homing and graft-cartilage integration.

Boushell MK, Mosher CZ, Suri GK, Doty SB, Strauss EJ, Hunziker EB, Lu HH.

Ann N Y Acad Sci. 2019 Apr;1442(1):138-152. doi: 10.1111/nyas.14054.

PMID:
30985969
2.

Enhanced biocompatibility and improved osteogenesis of coralline hydroxyapatite modified by bone morphogenetic protein 2 incorporated into a biomimetic coating.

Lin X, Hunziker EB, Liu T, Hu Q, Liu Y.

Mater Sci Eng C Mater Biol Appl. 2019 Mar;96:329-336. doi: 10.1016/j.msec.2018.11.017. Epub 2018 Nov 14.

PMID:
30606540
3.

Cells, soluble factors and matrix harmonically play the concert of allograft integration.

de Girolamo L, Ragni E, Cucchiarini M, van Bergen CJA, Hunziker EB, Chubinskaya S.

Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):1717-1725. doi: 10.1007/s00167-018-5182-1. Epub 2018 Oct 5. Review.

PMID:
30291395
4.

A Novel Experimental Dental Implant Permits Quantitative Grading of Surface-Property Effects on Osseointegration.

Hunziker EB, Spiegl-Habegger M, Rudolf S, Liu Y, Gu Z, Lippuner K, Shintani N, Enggist L.

Int J Oral Maxillofac Implants. 2018 Sep/Oct;33(5):967-978. doi: 10.11607/jomi.6348.

PMID:
30231082
5.

Elongation of the Long Bones in Humans by the Growth Plates.

Hunziker EB.

Nestle Nutr Inst Workshop Ser. 2018;89:13-23. doi: 10.1159/000486489. Epub 2018 Jul 10.

PMID:
29991028
6.

The kinetics and mechanism of bone morphogenetic protein 2 release from calcium phosphate-based implant-coatings.

Liu Y, Schouten C, Boerman O, Wu G, Jansen JA, Hunziker EB.

J Biomed Mater Res A. 2018 Sep;106(9):2363-2371. doi: 10.1002/jbm.a.36398.

PMID:
29569828
7.

Hyaluronic Acid Promotes the Osteogenesis of BMP-2 in an Absorbable Collagen Sponge.

Huang H, Feng J, Wismeijer D, Wu G, Hunziker EB.

Polymers (Basel). 2017 Aug 4;9(8). pii: E339. doi: 10.3390/polym9080339.

8.

The Acute Inflammatory Response to Absorbed Collagen Sponge Is Not Enhanced by BMP-2.

Huang H, Wismeijer D, Hunziker EB, Wu G.

Int J Mol Sci. 2017 Feb 25;18(3). pii: E498. doi: 10.3390/ijms18030498.

9.

Optimisation of BMP-2 dosage for the osseointegration of porous titanium implants in an ovine model.

Hunziker EB, Jovanovic J, Horner A, Keel MJ, Lippuner K, Shintani N.

Eur Cell Mater. 2016 Nov 18;32:241-256.

10.

Current strategies for integrative cartilage repair.

Boushell MK, Hung CT, Hunziker EB, Strauss EJ, Lu HH.

Connect Tissue Res. 2017 Sep;58(5):393-406. doi: 10.1080/03008207.2016.1231180. Epub 2016 Sep 6. Review.

PMID:
27599801
11.

Novel organ-slice culturing system to simulate meniscal repair: Proof of concept using a synovium-based pool of meniscoprogenitor cells.

Hunziker EB, Lippuner K, Keel MJ, Shintani N.

J Orthop Res. 2016 Sep;34(9):1588-96. doi: 10.1002/jor.23172. Epub 2016 Feb 11.

12.

Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development.

Niebler S, Schubert T, Hunziker EB, Bosserhoff AK.

Arthritis Res Ther. 2015 May 12;17:119. doi: 10.1186/s13075-015-0648-8.

13.

Age-Independent Cartilage Generation for Synovium-Based Autologous Chondrocyte Implantation.

Hunziker EB, Lippuner K, Keel MJ, Shintani N.

Tissue Eng Part A. 2015 Jul;21(13-14):2089-98. doi: 10.1089/ten.TEA.2014.0599. Epub 2015 Jun 4.

PMID:
25891184
14.

An educational review of cartilage repair: precepts & practice--myths & misconceptions--progress & prospects.

Hunziker EB, Lippuner K, Keel MJ, Shintani N.

Osteoarthritis Cartilage. 2015 Mar;23(3):334-50. doi: 10.1016/j.joca.2014.12.011. Epub 2014 Dec 19. Review.

15.

How best to preserve and reveal the structural intricacies of cartilaginous tissue.

Hunziker EB, Lippuner K, Shintani N.

Matrix Biol. 2014 Oct;39:33-43. doi: 10.1016/j.matbio.2014.08.010. Epub 2014 Aug 27. Review.

16.
17.

CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress.

Hall-Glenn F, Aivazi A, Akopyan L, Ong JR, Baxter RR, Benya PD, Goldschmeding R, van Nieuwenhoven FA, Hunziker EB, Lyons KM.

J Cell Commun Signal. 2013 Aug;7(3):219-30. doi: 10.1007/s12079-013-0201-y. Epub 2013 May 13.

18.

Modulation of human osteoblasts by metal surface chemistry.

Hofstetter W, Sehr H, de Wild M, Portenier J, Gobrecht J, Hunziker EB.

J Biomed Mater Res A. 2013 Aug;101(8):2355-64. doi: 10.1002/jbm.a.34541. Epub 2013 Jan 28.

PMID:
23359530
19.

Transport of anti-IL-6 antigen binding fragments into cartilage and the effects of injury.

Byun S, Sinskey YL, Lu YC, Ort T, Kavalkovich K, Sivakumar P, Hunziker EB, Frank EH, Grodzinsky AJ.

Arch Biochem Biophys. 2013 Apr 1;532(1):15-22. doi: 10.1016/j.abb.2012.12.020. Epub 2013 Jan 18.

20.

TGF-ß1 enhances the BMP-2-induced chondrogenesis of bovine synovial explants and arrests downstream differentiation at an early stage of hypertrophy.

Shintani N, Siebenrock KA, Hunziker EB.

PLoS One. 2013;8(1):e53086. doi: 10.1371/journal.pone.0053086. Epub 2013 Jan 3.

21.

Osseointegration: the slow delivery of BMP-2 enhances osteoinductivity.

Hunziker EB, Enggist L, Küffer A, Buser D, Liu Y.

Bone. 2012 Jul;51(1):98-106. doi: 10.1016/j.bone.2012.04.004. Epub 2012 Apr 13.

PMID:
22534475
22.

Bericht von der 25. Spektrometertagung (2011) in Schaffhausen.

Hunziker E.

Chimia (Aarau). 2011 Dec 14;65(12):976. No abstract available.

PMID:
28982452
24.

Functionalization of deproteinized bovine bone with a coating-incorporated depot of BMP-2 renders the material efficiently osteoinductive and suppresses foreign-body reactivity.

Wu G, Hunziker EB, Zheng Y, Wismeijer D, Liu Y.

Bone. 2011 Dec;49(6):1323-30. doi: 10.1016/j.bone.2011.09.046. Epub 2011 Sep 29.

PMID:
21983022
25.

Stereologic analysis of tibial-plateau cartilage and femoral cancellous bone in guinea pigs with spontaneous osteoarthritis.

Wang SX, Arsenault L, Hunziker EB.

Clin Orthop Relat Res. 2011 Oct;469(10):2796-805. doi: 10.1007/s11999-011-1899-6.

26.

Preclinical Studies for Cartilage Repair: Recommendations from the International Cartilage Repair Society.

Hurtig MB, Buschmann MD, Fortier LA, Hoemann CD, Hunziker EB, Jurvelin JS, Mainil-Varlet P, McIlwraith CW, Sah RL, Whiteside RA.

Cartilage. 2011 Apr;2(2):137-52. doi: 10.1177/1947603511401905.

27.

The elusive path to cartilage regeneration.

Hunziker EB.

Adv Mater. 2009 Sep 4;21(32-33):3419-24. doi: 10.1002/adma.200801957. No abstract available.

28.

The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rabbit.

Laverty S, Girard CA, Williams JM, Hunziker EB, Pritzker KP.

Osteoarthritis Cartilage. 2010 Oct;18 Suppl 3:S53-65. doi: 10.1016/j.joca.2010.05.029.

29.

Cartilage, bone and synovial histomorphometry in animal models of osteoarthritis.

Pastoureau PC, Hunziker EB, Pelletier JP.

Osteoarthritis Cartilage. 2010 Oct;18 Suppl 3:S106-12. doi: 10.1016/j.joca.2010.05.024. Review.

30.

The effect of a slow mode of BMP-2 delivery on the inflammatory response provoked by bone-defect-filling polymeric scaffolds.

Wu G, Liu Y, Iizuka T, Hunziker EB.

Biomaterials. 2010 Oct;31(29):7485-93. doi: 10.1016/j.biomaterials.2010.06.037.

PMID:
20638718
31.

Mechanical insertion properties of calcium-phosphate implant coatings.

Hägi TT, Enggist L, Michel D, Ferguson SJ, Liu Y, Hunziker EB.

Clin Oral Implants Res. 2010 Nov;21(11):1214-22. doi: 10.1111/j.1600-0501.2010.01916.x.

PMID:
20546252
33.

VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo.

Wernike E, Montjovent MO, Liu Y, Wismeijer D, Hunziker EB, Siebenrock KA, Hofstetter W, Klenke FM.

Eur Cell Mater. 2010 Feb 22;19:30-40.

34.

The influence of PRP on early bone formation in membrane protected defects. A histological and histomorphometric study in the rabbit calvaria.

Broggini N, Hofstetter W, Hunziker E, Bosshardt DD, Bornstein MM, Seto I, Weibrich G, Buser D.

Clin Implant Dent Relat Res. 2011 Mar;13(1):1-12. doi: 10.1111/j.1708-8208.2009.00266.x.

PMID:
20156229
35.

Cell-mediated BMP-2 liberation promotes bone formation in a mechanically unstable implant environment.

Hägi TT, Wu G, Liu Y, Hunziker EB.

Bone. 2010 May;46(5):1322-7. doi: 10.1016/j.bone.2010.02.010. Epub 2010 Feb 11.

PMID:
20153849
36.

Beta1 integrin deficiency results in multiple abnormalities of the knee joint.

Raducanu A, Hunziker EB, Drosse I, Aszódi A.

J Biol Chem. 2009 Aug 28;284(35):23780-92. doi: 10.1074/jbc.M109.039347. Epub 2009 Jul 7.

37.

Long-term cell-mediated protein release from calcium phosphate ceramics.

Wernike E, Hofstetter W, Liu Y, Wu G, Sebald HJ, Wismeijer D, Hunziker EB, Siebenrock KA, Klenke FM.

J Biomed Mater Res A. 2010 Feb;92(2):463-74. doi: 10.1002/jbm.a.32411.

PMID:
19195029
38.

Subcellular distribution of the insulin-like growth factor (IGF) binding proteins (IGFBPs) 2 and 3 in articular chondrocytes.

Sun T, Hunziker EB, Morales TI.

J Orthop Res. 2008 Nov;26(11):1421-7. doi: 10.1002/jor.20660.

39.

Surgical suturing of articular cartilage induces osteoarthritis-like changes.

Hunziker EB, Stähli A.

Osteoarthritis Cartilage. 2008 Sep;16(9):1067-73. doi: 10.1016/j.joca.2008.01.009. Epub 2008 Mar 4.

40.

Accelerated hypertrophic chondrocyte kinetics in GDF-7 deficient murine tibial growth plates.

Mikic B, Ferreira MP, Battaglia TC, Hunziker EB.

J Orthop Res. 2008 Jul;26(7):986-90. doi: 10.1002/jor.20574.

41.

Incorporation of growth factors into medical devices via biomimetic coatings.

Liu Y, Li JP, Hunziker EB, de Groot K.

Philos Trans A Math Phys Eng Sci. 2006 Jan 15;364(1838):233-48. doi: 10.1098/rsta.2005.1685. Review.

PMID:
18272464
42.

Site-1 protease is essential for endochondral bone formation in mice.

Patra D, Xing X, Davies S, Bryan J, Franz C, Hunziker EB, Sandell LJ.

J Cell Biol. 2007 Nov 19;179(4):687-700.

43.

Cartilage histomorphometry.

Hunziker EB.

Methods Mol Med. 2007;135:147-66.

PMID:
17951657
44.

Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo.

Klenke FM, Liu Y, Yuan H, Hunziker EB, Siebenrock KA, Hofstetter W.

J Biomed Mater Res A. 2008 Jun 1;85(3):777-86.

PMID:
17896777
45.

Evaluation of a novel biphasic calcium phosphate in standardized bone defects: a histologic and histomorphometric study in the mandibles of minipigs.

Jensen SS, Yeo A, Dard M, Hunziker E, Schenk R, Buser D.

Clin Oral Implants Res. 2007 Dec;18(6):752-60. Epub 2007 Sep 20.

PMID:
17888014
46.

Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) is closely associated with the chondrocyte nucleus in human articular cartilage.

Hunziker EB, Kapfinger E, Martin J, Buckwalter J, Morales TI.

Osteoarthritis Cartilage. 2008 Feb;16(2):185-94. Epub 2007 Aug 13.

48.

Translation from research to applications.

Hunziker E, Spector M, Libera J, Gertzman A, Woo SL, Ratcliffe A, Lysaght M, Coury A, Kaplan D, Vunjak-Novakovic G.

Tissue Eng. 2006 Dec;12(12):3341-64. Review.

PMID:
17518672
49.

Abnormal collagen fibrils in cartilage of matrilin-1/matrilin-3-deficient mice.

Nicolae C, Ko YP, Miosge N, Niehoff A, Studer D, Enggist L, Hunziker EB, Paulsson M, Wagener R, Aszodi A.

J Biol Chem. 2007 Jul 27;282(30):22163-75. Epub 2007 May 14.

50.

Chondrogenic potential of human synovial mesenchymal stem cells in alginate.

Kurth T, Hedbom E, Shintani N, Sugimoto M, Chen FH, Haspl M, Martinovic S, Hunziker EB.

Osteoarthritis Cartilage. 2007 Oct;15(10):1178-89. Epub 2007 May 14.

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