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Items: 1 to 50 of 107

1.

A Convergent Approach to Diverse Spiroethers through Stereoselective Trapping of Rhodium Carbenoids with Gold-Activated Alkynols.

Hunter AC, Schlitzer SC, Stevens JC, Almutwalli B, Sharma I.

J Org Chem. 2018 Mar 2;83(5):2744-2752. doi: 10.1021/acs.joc.7b03196. Epub 2018 Feb 15.

PMID:
29384670
2.

Quartz Crystal Microbalance Assay of Clinical Calcinosis Samples and Their Synthetic Models Differentiates the Efficacy of Chelation-Based Treatments.

Fei F, Gallas A, Chang YC, Rao Y, Hunter AC, Winpenny REP, Herrick AL, Lockyer NP, Blanford CF.

ACS Appl Mater Interfaces. 2017 Aug 23;9(33):27544-27552. doi: 10.1021/acsami.7b08423. Epub 2017 Aug 15.

PMID:
28752990
3.

Metabolism of steroidal lactones by the fungus Corynespora cassiicola CBS 161.60 results in a mechanistically unique intramolecular ring-D cyclization resulting in C-14 spiro-lactones.

Hunter AC, Oni YI, Dodd HT, Raftery J, Gardiner JM, Uttley M.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Sep;1862(9):939-945. doi: 10.1016/j.bbalip.2017.06.003. Epub 2017 Jun 9.

PMID:
28606744
4.

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes.

Wibroe PP, Anselmo AC, Nilsson PH, Sarode A, Gupta V, Urbanics R, Szebeni J, Hunter AC, Mitragotri S, Mollnes TE, Moghimi SM.

Nat Nanotechnol. 2017 Jul;12(6):589-594. doi: 10.1038/nnano.2017.47. Epub 2017 Apr 10.

PMID:
28396605
5.

AFM visualization of sub-50nm polyplex disposition to the nuclear pore complex without compromising the integrity of the nuclear envelope.

Andersen H, Parhamifar L, Hunter AC, Shahin V, Moghimi SM.

J Control Release. 2016 Dec 28;244(Pt A):24-29. doi: 10.1016/j.jconrel.2016.11.008. Epub 2016 Nov 11.

PMID:
27845193
6.

Synergistic Diazo-OH Insertion/Conia-Ene Cascade Catalysis for the Stereoselective Synthesis of γ-Butyrolactones and Tetrahydrofurans.

Hunter AC, Schlitzer SC, Sharma I.

Chemistry. 2016 Nov 2;22(45):16062-16065. doi: 10.1002/chem.201603934. Epub 2016 Sep 16.

PMID:
27555522
7.

Canonical Poly(A) Polymerase Activity Promotes the Decay of a Wide Variety of Mammalian Nuclear RNAs.

Bresson SM, Hunter OV, Hunter AC, Conrad NK.

PLoS Genet. 2015 Oct 20;11(10):e1005610. doi: 10.1371/journal.pgen.1005610. eCollection 2015 Oct.

8.

Platelet mimicry: The emperor's new clothes?

Moghimi SM, Hunter AC, Peer D.

Nanomedicine. 2016 Jan;12(1):245-8. doi: 10.1016/j.nano.2015.09.005. Epub 2015 Sep 25.

PMID:
26409192
9.

Metabolic fate of 3α,5-cycloandrostanes in the endogenous lactonization pathway of Aspergillus tamarii KITA.

Hunter AC, Patel S, Dedi C, Dodd HT, Bryce RA.

Phytochemistry. 2015 Nov;119:19-25. doi: 10.1016/j.phytochem.2015.09.003. Epub 2015 Sep 11.

PMID:
26372080
10.

Complement monitoring of Pluronic 127 gel and micelles: suppression of copolymer-mediated complement activation by elevated serum levels of HDL, LDL, and apolipoproteins AI and B-100.

Hamad I, Hunter AC, Moghimi SM.

J Control Release. 2013 Sep 10;170(2):167-74. doi: 10.1016/j.jconrel.2013.05.030. Epub 2013 Jun 4.

PMID:
23747733
11.

Surfactant-mediated complement activation in beagle dogs.

Moghimi SM, Wibroe PP, Szebeni J, Hunter AC.

Int Immunopharmacol. 2013 Sep;17(1):33-4. doi: 10.1016/j.intimp.2013.05.012. Epub 2013 Jun 2. No abstract available.

PMID:
23735233
12.

Smooth muscle relaxation and activation of the large conductance Ca(++)-activated K+ (BK(Ca)) channel by novel oestrogens.

Maher J, Hunter AC, Mabley JG, Lippiat J, Allen MC.

Br J Pharmacol. 2013 Jul;169(5):1153-65. doi: 10.1111/bph.12211.

13.

Complement activation by PEG-functionalized multi-walled carbon nanotubes is independent of PEG molecular mass and surface density.

Andersen AJ, Windschiegl B, Ilbasmis-Tamer S, Degim IT, Hunter AC, Andresen TL, Moghimi SM.

Nanomedicine. 2013 May;9(4):469-73. doi: 10.1016/j.nano.2013.01.011. Epub 2013 Feb 19.

PMID:
23434678
14.

Single-walled carbon nanotube surface control of complement recognition and activation.

Andersen AJ, Robinson JT, Dai H, Hunter AC, Andresen TL, Moghimi SM.

ACS Nano. 2013 Feb 26;7(2):1108-19. doi: 10.1021/nn3055175. Epub 2013 Jan 16.

PMID:
23301860
15.

Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective.

Hunter AC, Elsom J, Wibroe PP, Moghimi SM.

Nanomedicine. 2012 Sep;8 Suppl 1:S5-20. doi: 10.1016/j.nano.2012.07.005. Epub 2012 Jul 27. Review.

PMID:
22846372
16.

Particulate systems for targeting of macrophages: basic and therapeutic concepts.

Moghimi SM, Parhamifar L, Ahmadvand D, Wibroe PP, Andresen TL, Farhangrazi ZS, Hunter AC.

J Innate Immun. 2012;4(5-6):509-28. doi: 10.1159/000339153. Epub 2012 Jun 19. Review.

17.

Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective.

Hunter AC, Elsom J, Wibroe PP, Moghimi SM.

Maturitas. 2012 Sep;73(1):5-18. doi: 10.1016/j.maturitas.2012.05.014. Epub 2012 Jun 17. Review.

PMID:
22709523
18.

Genomic perspectives in inter-individual adverse responses following nanomedicine administration: The way forward.

Moghimi SM, Wibroe PP, Helvig SY, Farhangrazi ZS, Hunter AC.

Adv Drug Deliv Rev. 2012 Oct;64(13):1385-93. doi: 10.1016/j.addr.2012.05.010. Epub 2012 May 23. Review.

PMID:
22634158
19.

Complement system and the brain: selected pathologies and avenues toward engineering of neurological nanomedicines.

Lettiero B, Andersen AJ, Hunter AC, Moghimi SM.

J Control Release. 2012 Jul 20;161(2):283-9. doi: 10.1016/j.jconrel.2011.10.036. Epub 2011 Nov 7. Review.

PMID:
22094105
20.

Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective.

Moghimi SM, Hunter AC, Andresen TL.

Annu Rev Pharmacol Toxicol. 2012;52:481-503. doi: 10.1146/annurev-pharmtox-010611-134623. Epub 2011 Oct 24. Review.

PMID:
22035254
21.
22.

Polyethylenimine-mediated impairment of mitochondrial membrane potential, respiration and membrane integrity: implications for nucleic acid delivery and gene therapy.

Larsen AK, Malinska D, Koszela-Piotrowska I, Parhamifar L, Hunter AC, Moghimi SM.

Mitochondrion. 2012 Jan;12(1):162-8. doi: 10.1016/j.mito.2011.08.013. Epub 2011 Sep 10.

PMID:
21925619
23.

Complement monitoring of nanomedicines and implants.

Moghimi SM, Hunter AC.

Adv Drug Deliv Rev. 2011 Sep 16;63(12):963-4. doi: 10.1016/j.addr.2011.06.008. Epub 2011 Jun 29. No abstract available.

PMID:
21745510
24.

Material properties in complement activation.

Moghimi SM, Andersen AJ, Ahmadvand D, Wibroe PP, Andresen TL, Hunter AC.

Adv Drug Deliv Rev. 2011 Sep 16;63(12):1000-7. doi: 10.1016/j.addr.2011.06.002. Epub 2011 Jun 12. Review.

PMID:
21689701
25.

Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering.

Hamad I, Al-Hanbali O, Hunter AC, Rutt KJ, Andresen TL, Moghimi SM.

ACS Nano. 2010 Nov 23;4(11):6629-38. doi: 10.1021/nn101990a. Epub 2010 Oct 28.

PMID:
21028845
26.

Transformation of a series of saturated isomeric steroidal diols by Aspergillus tamarii KITA reveals a precise stereochemical requirement for entrance into the lactonization pathway.

Hunter AC, Collins C, Dodd HT, Dedi C, Koussoroplis SJ.

J Steroid Biochem Mol Biol. 2010 Nov;122(5):352-8. doi: 10.1016/j.jsbmb.2010.08.010. Epub 2010 Sep 9.

PMID:
20832471
27.

Complement monitoring of carbon nanotubes.

Moghimi SM, Hunter AC.

Nat Nanotechnol. 2010 Jun;5(6):382; author reply 382-3. doi: 10.1038/nnano.2010.109. No abstract available.

PMID:
20523330
28.

Complement activation cascade triggered by PEG-PL engineered nanomedicines and carbon nanotubes: the challenges ahead.

Moghimi SM, Andersen AJ, Hashemi SH, Lettiero B, Ahmadvand D, Hunter AC, Andresen TL, Hamad I, Szebeni J.

J Control Release. 2010 Sep 1;146(2):175-81. doi: 10.1016/j.jconrel.2010.04.003. Epub 2010 Apr 11.

PMID:
20388529
29.

Cationic carriers of genetic material and cell death: a mitochondrial tale.

Hunter AC, Moghimi SM.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1203-9. doi: 10.1016/j.bbabio.2010.03.026. Epub 2010 Apr 8. Review.

30.

Application of the quartz crystal microbalance to nanomedicine.

Hunter AC.

J Biomed Nanotechnol. 2009 Dec;5(6):669-75. Review.

PMID:
20201228
31.

Complement: alive and kicking nanomedicines.

Andersen AJ, Hashemi SH, Andresen TL, Hunter AC, Moghimi SM.

J Biomed Nanotechnol. 2009 Aug;5(4):364-72. Review.

PMID:
20055082
32.

An unusual ring--a opening and other reactions in steroid transformation by the thermophilic fungus Myceliophthora thermophila.

Hunter AC, Watts KR, Dedi C, Dodd HT.

J Steroid Biochem Mol Biol. 2009 Sep;116(3-5):171-7. doi: 10.1016/j.jsbmb.2009.05.012. Epub 2009 May 29.

PMID:
19482085
33.

Transformation of 5-ene steroids by the fungus Aspergillus tamarii KITA: mixed molecular fate in lactonization and hydroxylation pathways with identification of a putative 3beta-hydroxy-steroid dehydrogenase/Delta5-Delta4 isomerase pathway.

Hunter AC, Coyle E, Morse F, Dedi C, Dodd HT, Koussoroplis SJ.

Biochim Biophys Acta. 2009 Feb;1791(2):110-7. doi: 10.1016/j.bbalip.2008.12.005. Epub 2008 Dec 24.

PMID:
19136076
34.

Poly(ethylene glycol)s generate complement activation products in human serum through increased alternative pathway turnover and a MASP-2-dependent process.

Hamad I, Hunter AC, Szebeni J, Moghimi SM.

Mol Immunol. 2008 Dec;46(2):225-32. doi: 10.1016/j.molimm.2008.08.276. Epub 2008 Oct 11.

PMID:
18849076
35.

Natural Products and Medicinal Chemistry--the 22nd Mona Symposium.

Hunter AC.

IDrugs. 2008 Mar;11(3):169-70. No abstract available.

PMID:
18311649
36.

Novel quartz crystal microbalance based biosensor for detection of oral epithelial cell-microparticle interaction in real-time.

Elsom J, Lethem MI, Rees GD, Hunter AC.

Biosens Bioelectron. 2008 Mar 14;23(8):1259-65. doi: 10.1016/j.bios.2007.11.020. Epub 2007 Dec 7.

PMID:
18207383
37.

Predominant allylic hydroxylation at carbons 6 and 7 of 4 and 5-ene functionalized steroids by the thermophilic fungus Rhizomucor tauricus IMI23312.

Hunter AC, Mills PW, Dedi C, Dodd HT.

J Steroid Biochem Mol Biol. 2008 Jan;108(1-2):155-63. Epub 2007 Sep 29.

PMID:
17981459
38.

Ordering of binary polymeric nanoparticles on hydrophobic surfaces assembled from low volume fraction dispersions.

Mukhopadhyay R, Al-Hanbali O, Pillai S, Hemmersam AG, Meyer RL, Hunter AC, Rutt KJ, Besenbacher F, Moghimi SM, Kingshott P.

J Am Chem Soc. 2007 Nov 7;129(44):13390-1. Epub 2007 Oct 11. No abstract available.

PMID:
17929818
39.

Perceptions of stress among students participating in psychology research: a canadian survey.

Flagel DC, Best LA, Hunter AC.

J Empir Res Hum Res Ethics. 2007 Sep;2(3):61-7. doi: 10.1525/jer.2007.2.3.61.

PMID:
19385852
40.

Particulate nanomedicine in the footsteps of platelet homing.

Moghimi SM, Hamad I, Hunter AC.

Nanomedicine (Lond). 2007 Jun;2(3):381-4. No abstract available.

PMID:
17716182
42.

Modification of the Stewart biphasic colorimetric assay for stable and accurate quantitative determination of Pluronic and Tetronic block copolymers for application in biological systems.

Al-Hanbali O, Onwuzo NM, Rutt KJ, Dadswell CM, Moghimi SM, Hunter AC.

Anal Biochem. 2007 Feb 15;361(2):287-93. Epub 2006 Dec 20.

PMID:
17196543
43.

Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity.

Hunter AC.

Adv Drug Deliv Rev. 2006 Dec 1;58(14):1523-31. Epub 2006 Sep 28. Review.

PMID:
17079050
44.

Concentration dependent structural ordering of poloxamine 908 on polystyrene nanoparticles and their modulatory role on complement consumption.

Al-Hanbali O, Rutt KJ, Sarker DK, Hunter AC, Moghimi SM.

J Nanosci Nanotechnol. 2006 Sep-Oct;6(9-10):3126-33.

PMID:
17048527
45.

Activation of the human complement system by cholesterol-rich and PEGylated liposomes-modulation of cholesterol-rich liposome-mediated complement activation by elevated serum LDL and HDL levels.

Moein Moghimi S, Hamad I, Bünger R, Andresen TL, Jørgensen K, Hunter AC, Baranji L, Rosivall L, Szebeni J.

J Liposome Res. 2006;16(3):167-74.

PMID:
16952871
47.

Low and high molecular weight poly(L-lysine)s/poly(L-lysine)-DNA complexes initiate mitochondrial-mediated apoptosis differently.

Symonds P, Murray JC, Hunter AC, Debska G, Szewczyk A, Moghimi SM.

FEBS Lett. 2005 Nov 7;579(27):6191-8. Epub 2005 Oct 13.

49.

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy.

Moghimi SM, Symonds P, Murray JC, Hunter AC, Debska G, Szewczyk A.

Mol Ther. 2005 Jun;11(6):990-5.

50.

Fate of novel Quasi reverse steroidal substrates by Aspergillus tamarii KITA: bypass of lactonisation and an exclusive role for the minor hydroxylation pathway.

Hunter AC, Kennedy S, Clabby SJ, Elsom J.

Biochim Biophys Acta. 2005 May 15;1734(2):190-7. Epub 2005 Mar 9.

PMID:
15904875

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