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High Glucose Induces Mesangial Cell Apoptosis through miR-15b-5p and Promotes Diabetic Nephropathy by Extracellular Vesicle Delivery.

Tsai YC, Kuo MC, Hung WW, Wu LY, Wu PH, Chang WA, Kuo PL, Hsu YL.

Mol Ther. 2020 Mar 4;28(3):963-974. doi: 10.1016/j.ymthe.2020.01.014. Epub 2020 Jan 15.


Factors associated with quality of life in patients with diabetic hypoglycaemia.

Huang MC, Hung CH, Chen CY, Hung WW, Liang HL.

J Clin Nurs. 2020 Jan 16. doi: 10.1111/jocn.15183. [Epub ahead of print]


GRECC Connect: Geriatrics Telehealth to Empower Health Care Providers and Improve Management of Older Veterans in Rural Communities.

Pimentel CB, Gately M, Barczi SR, Boockvar KS, Bowman EH, Caprio TV, Colón-Emeric CS, Dang S, Espinoza SE, Garner KK, Griffiths PC, Howe JL, Lum HD, Markland AD, Rossi MI, Thielke SM, Valencia-Rodrigo WM, Moo LR, Hung WW.

Fed Pract. 2019 Oct;36(10):464-470.


Training Programs on Geriatrics in Rural Areas: A Review.

Hintenach A, Raphael O, Hung WW.

Curr Geriatr Rep. 2019 Apr 16;8(2):117-122.


Clinical Approaches and Emerging Therapeutics for Frailty Syndrome.

Hung WW.

Clin Ther. 2019 Mar;41(3):374-375. doi: 10.1016/j.clinthera.2019.02.005. Epub 2019 Feb 26. No abstract available.


Successful management of type IV hypersensitivity reactions to human insulin analogue with injecting mixtures of biphasic insulin aspart and dexamethasone.

Wen WL, Tsai KB, Lin YH, Hwang SJ, Hsiao PJ, Shin SJ, Hung WW.

J Formos Med Assoc. 2019 Apr;118(4):843-848. doi: 10.1016/j.jfma.2019.01.004. Epub 2019 Jan 28.


Using groEL as the target for identification of Enterococcus faecium clades and 7 clinically relevant Enterococcus species.

Hung WW, Chen YH, Tseng SP, Jao YT, Teng LJ, Hung WC.

J Microbiol Immunol Infect. 2019 Apr;52(2):255-264. doi: 10.1016/j.jmii.2018.10.008. Epub 2018 Nov 14.


The Interaction of miR-378i-Skp2 Regulates Cell Senescence in Diabetic Nephropathy.

Tsai YC, Kuo PL, Kuo MC, Hung WW, Wu LY, Chang WA, Wu PH, Lee SC, Chen HC, Hsu YL.

J Clin Med. 2018 Nov 22;7(12). pii: E468. doi: 10.3390/jcm7120468.


Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy.

Tsai YC, Kuo PL, Hung WW, Wu LY, Wu PH, Chang WA, Kuo MC, Hsu YL.

Mol Ther Nucleic Acids. 2018 Dec 7;13:543-555. doi: 10.1016/j.omtn.2018.10.003. Epub 2018 Oct 10.


Optimizing Cancer Treatment for Older Adults.

Hung WW.

Clin Ther. 2018 Apr;40(4):502-503. doi: 10.1016/j.clinthera.2018.03.011. Epub 2018 Apr 2. No abstract available.


An Interdisciplinary Academic Detailing Approach to Decrease Inappropriate Medication Prescribing by Physician Residents for Older Veterans Treated in the Emergency Department.

Moss JM, Bryan WE 3rd, Wilkerson LM, King HA, Jackson GL, Owenby RK, Van Houtven CH, Stevens MB, Powers J, Vaughan CP, Hung WW, Hwang U, Markland AD, Sloane R, Knaack W, Hastings SN.

J Pharm Pract. 2019 Apr;32(2):167-174. doi: 10.1177/0897190017747424. Epub 2017 Dec 25.


Teaching Geriatric Concepts in Internal Medicine Residency Continuity Clinic Did Not Affect Practice.

Chang C, Hung WW, Bhatia S, Thomas DC, Leipzig RM, DeCherrie LV, Callahan EH.

J Am Geriatr Soc. 2018 Feb;66(2):420-421. doi: 10.1111/jgs.15152. Epub 2017 Oct 23. No abstract available.


Liraglutide and Renal Outcomes in Type 2 Diabetes.

Mann JFE, Ørsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, Tornøe K, Zinman B, Buse JB; LEADER Steering Committee and Investigators.

N Engl J Med. 2017 Aug 31;377(9):839-848. doi: 10.1056/NEJMoa1616011.


mecA-related structure in methicillin-resistant coagulase-negative staphylococci from street food in Taiwan.

Yang TY, Hung WW, Lin L, Hung WC, Tseng SP.

Sci Rep. 2017 Feb 9;7:42205. doi: 10.1038/srep42205.


Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.

Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB; LEADER Steering Committee; LEADER Trial Investigators.

N Engl J Med. 2016 Jul 28;375(4):311-22. doi: 10.1056/NEJMoa1603827. Epub 2016 Jun 13.


Transitional Care Outcomes in Older Spanish-English Bilingual Veterans.

O'Kula SS, Gottesman E, Jones S, Signor D, Hung WW, Boockvar KS.

J Am Geriatr Soc. 2016 May;64(5):1132-3. doi: 10.1111/jgs.14116. No abstract available.


Impact of Clinical Pharmacy Specialists on the Design and Implementation of a Quality Improvement Initiative to Decrease Inappropriate Medications in a Veterans Affairs Emergency Department.

Moss JM, Bryan WE 3rd, Wilkerson LM, Jackson GL, Owenby RK, Van Houtven C, Stevens MB, Powers JS, Vaughan CP, Hung WW, Hwang U, Markland AD, McGwin G, Hastings SN.

J Manag Care Spec Pharm. 2016 Jan;22(1):74-80. doi: 10.18553/jmcp.2016.22.1.74.


Geriatric orthopedic co-management of older adults with hip fracture: an emerging standard.

Chen P, Hung WW.

Ann Transl Med. 2015 Sep;3(16):224. doi: 10.3978/j.issn.2305-5839.2015.07.13.


Predictors and outcomes of unplanned readmission to a different hospital.

Kim H, Hung WW, Paik MC, Ross JS, Zhao Z, Kim GS, Boockvar K.

Int J Qual Health Care. 2015 Dec;27(6):513-9. doi: 10.1093/intqhc/mzv082. Epub 2015 Oct 15.


A model for integrating the assessment and management of geriatric syndromes into internal medicine continuity practice: 5-year report.

Chang C, Callahan EH, Hung WW, Thomas DC, Leipzig RM, DeCherrie LV.

Gerontol Geriatr Educ. 2017 Jul-Sep;38(3):271-282. doi: 10.1080/02701960.2015.1031897. Epub 2015 Jul 9.


Enhancing the Quality of Prescribing Practices for Older Veterans Discharged from the Emergency Department (EQUiPPED): Preliminary Results from Enhancing Quality of Prescribing Practices for Older Veterans Discharged from the Emergency Department, a Novel Multicomponent Interdisciplinary Quality Improvement Initiative.

Stevens MB, Hastings SN, Powers J, Vandenberg AE, Echt KV, Bryan WE 3rd, Peggs K, Markland AD, Hwang U, Hung WW, Schmidt AJ, McGwin G, Ikpe-Ekpo E, Clevenger C, Johnson TM 2nd, Vaughan CP.

J Am Geriatr Soc. 2015 May;63(5):1025-9. doi: 10.1111/jgs.13404. Epub 2015 May 6.


The American Geriatrics Society/National Institute on Aging Bedside-to-Bench Conference: Research Agenda on Delirium in Older Adults.

AGS/NIA Delirium Conference Writing Group, Planning Committee and Faculty.

J Am Geriatr Soc. 2015 May;63(5):843-52. doi: 10.1111/jgs.13406. Epub 2015 Mar 31. No abstract available.


Opioid interruptions, pain, and withdrawal symptoms in nursing home residents.

Redding SE, Liu S, Hung WW, Boockvar KS.

Clin Ther. 2014 Nov 1;36(11):1555-63. doi: 10.1016/j.clinthera.2014.10.013. Epub 2014 Nov 19.


Emergence of Panton-Valentine leukocidin-positive ST59 methicillin-susceptible Staphylococcus aureus with high cytolytic peptide expression in association with community-acquired pediatric osteomyelitis complicated by pulmonary embolism.

Sawanobori E, Hung WC, Takano T, Hachuda K, Horiuchi T, Higuchi W, Hung WW, Iwao Y, Nishiyama A, Reva I, Reva G, Teng LJ, Yamamoto T.

J Microbiol Immunol Infect. 2015 Oct;48(5):565-73. doi: 10.1016/j.jmii.2014.04.015. Epub 2014 Jul 26.


A multisite geriatric education program for rural providers in the Veteran Health Care System (GRECC-Connect).

Hung WW, Rossi M, Thielke S, Caprio T, Barczi S, Kramer BJ, Kochersberger G, Boockvar KS, Brody A, Howe JL.

Gerontol Geriatr Educ. 2014;35(1):23-40. doi: 10.1080/02701960.2013.870902. Review.


A case of acromegaly complicated with diabetic ketoacidosis, pituitary apoplexy, and lymphoma.

Jiang HJ, Hung WW, Hsiao PJ.

Kaohsiung J Med Sci. 2013 Dec;29(12):687-90. doi: 10.1016/j.kjms.2013.08.002. Epub 2013 Sep 10.


Specific interactions between the quaternary ammonium oligoether-based ionic liquid and water as a function of pressure.

Chang HC, Jiang JC, Chen TY, Wang HS, Li LY, Hung WW, Lin SH.

Phys Chem Chem Phys. 2013 Aug 14;15(30):12734-41. doi: 10.1039/c3cp51396c.


Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver.

Hsiao PJ, Chen ZC, Hung WW, Yang YH, Lee MY, Huang JF, Kuo KK.

BMC Med Genet. 2013 May 20;14:54. doi: 10.1186/1471-2350-14-54.


Evaluation of the Mobile Acute Care of the Elderly (MACE) service.

Hung WW, Ross JS, Farber J, Siu AL.

JAMA Intern Med. 2013 Jun 10;173(11):990-6. doi: 10.1001/jamainternmed.2013.478.


Hip fracture management: tailoring care for the older patient.

Hung WW, Egol KA, Zuckerman JD, Siu AL.

JAMA. 2012 May 23;307(20):2185-94. doi: 10.1001/jama.2012.4842.


Association of chronic diseases and impairments with disability in older adults: a decade of change?

Hung WW, Ross JS, Boockvar KS, Siu AL.

Med Care. 2012 Jun;50(6):501-7. doi: 10.1097/MLR.0b013e318245a0e0.


Common dietary supplements for cognitive health.

Gestuvo M, Hung W.

Aging health. 2012 Feb;8(1):89-97.


Increased unbound retinol-binding protein 4 concentration induces apoptosis through receptor-mediated signaling.

Chen CH, Hsieh TJ, Lin KD, Lin HY, Lee MY, Hung WW, Hsiao PJ, Shin SJ.

J Biol Chem. 2012 Mar 23;287(13):9694-707. doi: 10.1074/jbc.M111.301721. Epub 2012 Feb 3.



Kung Pui L, Hung WW, M Yamin B, Kassim MB.

Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o1892. doi: 10.1107/S1600536811025207. Epub 2011 Jul 2.


Thyroid autoantibodies and dysfunction do not impact the treatment efficacy of peginterferon and ribavirin combination therapy in chronic hepatitis C.

Huang JF, Huang CK, Yu ML, Dai CY, Huang CF, Hung WW, Yeh ML, Hsieh MH, Yang JF, Hsieh MY, Lin ZY, Chen SC, Wu SS, Chuang WL.

Hepatol Int. 2012 Jun;6(3):613-9. doi: 10.1007/s12072-011-9308-5. Epub 2011 Aug 18.


Recent trends in chronic disease, impairment and disability among older adults in the United States.

Hung WW, Ross JS, Boockvar KS, Siu AL.

BMC Geriatr. 2011 Aug 18;11:47. doi: 10.1186/1471-2318-11-47.


Hip fracture: a complex illness among complex patients.

Hung WW, Morrison RS.

Ann Intern Med. 2011 Aug 16;155(4):267-8. doi: 10.7326/0003-4819-155-4-201108160-00012. No abstract available.


Enzyme replacement therapy for mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): experience in Hong Kong.

But WM, Wong MY, Chow JC, Chan WK, Ko WT, Wu SP, Wong ML, Miu TY, Tse WY, Hung WW, Fan TW, Shek CC.

Hong Kong Med J. 2011 Aug;17(4):317-24.


Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes.

Hung WW, Hsieh TJ, Lin T, Chou PC, Hsiao PJ, Lin KD, Shin SJ.

Cardiovasc Drugs Ther. 2011 Feb;25(1):3-12. doi: 10.1007/s10557-010-6274-4.



Hung WW, Hassan IN, Yamin BM, Kassim MB.

Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 9;66(Pt 2):o314. doi: 10.1107/S1600536809055834.


Medullary thyroid carcinoma with poor differentiation and atypical radiographic pattern of metastasis.

Hung WW, Wang CS, Tsai KB, Ou-Yang F, Shin SJ, Hsiao PJ.

Pathol Int. 2009 Sep;59(9):660-3. doi: 10.1111/j.1440-1827.2009.02423.x.


The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development.

Broitman-Maduro G, Owraghi M, Hung WW, Kuntz S, Sternberg PW, Maduro MF.

Development. 2009 Aug;136(16):2735-46. doi: 10.1242/dev.038307. Epub 2009 Jul 15.


Cognitive decline among patients with chronic obstructive pulmonary disease.

Hung WW, Wisnivesky JP, Siu AL, Ross JS.

Am J Respir Crit Care Med. 2009 Jul 15;180(2):134-7. doi: 10.1164/rccm.200902-0276OC. Epub 2009 May 7.


Knockdown of SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification in C. briggsae as compared with C. elegans.

Lin KT, Broitman-Maduro G, Hung WW, Cervantes S, Maduro MF.

Dev Biol. 2009 Jan 1;325(1):296-306. doi: 10.1016/j.ydbio.2008.10.001. Epub 2008 Oct 19.


Antihypertensive therapy with indapamide and perindopril reduced mortality in patients >=80 years.

Hung WW, Leipzig RM.

Evid Based Med. 2008 Oct;13(5):136. doi: 10.1136/ebm.13.5.136. No abstract available.


Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet.

Hsiao PJ, Hsieh TJ, Kuo KK, Hung WW, Tsai KB, Yang CH, Yu ML, Shin SJ.

BMC Mol Biol. 2008 Sep 26;9:82. doi: 10.1186/1471-2199-9-82.


Antihypertensive therapy with indapamide and perindopril reduced mortality in patients greater than or equal to 80 years.

Hung WW, Leipzig RM.

ACP J Club. 2008 Aug 19;149(2):10. No abstract available.


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