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A single-cell transcriptome atlas of the adult human retina.

Lukowski SW, Lo CY, Sharov AA, Nguyen Q, Fang L, Hung SS, Zhu L, Zhang T, Grünert U, Nguyen T, Senabouth A, Jabbari JS, Welby E, Sowden JC, Waugh HS, Mackey A, Pollock G, Lamb TD, Wang PY, Hewitt AW, Gillies MC, Powell JE, Wong RC.

EMBO J. 2019 Sep 16;38(18):e100811. doi: 10.15252/embj.2018100811. Epub 2019 Aug 22.


Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina.

Li F, Hung SSC, Mohd Khalid MKN, Wang JH, Chrysostomou V, Wong VHY, Singh V, Wing K, Tu L, Bender JA, Pébay A, King AE, Cook AL, Wong RCB, Bui BV, Hewitt AW, Liu GS.

Hum Gene Ther. 2019 Nov;30(11):1349-1360. doi: 10.1089/hum.2019.021. Epub 2019 Oct 25.


Integrative genomic analysis identifies key pathogenic mechanisms in primary mediastinal large B-cell lymphoma.

Mottok A, Hung SS, Chavez EA, Woolcock B, Telenius A, Chong LC, Meissner B, Nakamura H, Rushton C, Viganò E, Sarkozy C, Gascoyne RD, Connors JM, Ben-Neriah S, Mungall A, Marra MA, Siebert R, Scott DW, Savage KJ, Steidl C.

Blood. 2019 Sep 5;134(10):802-813. doi: 10.1182/blood.2019001126. Epub 2019 Jul 10.


Metabolic adaptation to feed restriction on the green sturgeon (Acipenser medirostris) fingerlings.

Lin CY, Huang LH, Deng DF, Lee SH, Liang HJ, Hung SSO.

Sci Total Environ. 2019 Sep 20;684:78-88. doi: 10.1016/j.scitotenv.2019.05.044. Epub 2019 May 11.


Corrigendum: Potentials of Cellular Reprogramming as a Novel Strategy for Neuroregeneration.

Fang L, El Wazan L, Tan C, Nguyen T, Hung SSC, Hewitt AW, Wong RCB.

Front Cell Neurosci. 2019 May 3;13:147. doi: 10.3389/fncel.2019.00147. eCollection 2019.


Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant.

Tran MTN, Khalid MKNM, Pébay A, Cook AL, Liang HH, Wong RCB, Craig JE, Liu GS, Hung SS, Hewitt AW.

Mol Vis. 2019 Mar 16;25:174-182. eCollection 2019.


Noneffectiveness of electroacupuncture for comorbid generalized anxiety disorder and irritable bowel syndrome.

Mak AD, Chung VCH, Yuen SY, Tse YK, Wong SYS, Ju Y, Hung SS, Leung KC, You JHS, Lui R, Wong SH, Leung ONW, Lam LCW, Lee S, Wu JCY.

J Gastroenterol Hepatol. 2019 Oct;34(10):1736-1742. doi: 10.1111/jgh.14667. Epub 2019 Apr 10.


A Simple Cloning-free Method to Efficiently Induce Gene Expression Using CRISPR/Cas9.

Fang L, Hung SSC, Yek J, El Wazan L, Nguyen T, Khan S, Lim SY, Hewitt AW, Wong RCB.

Mol Ther Nucleic Acids. 2019 Mar 1;14:184-191. doi: 10.1016/j.omtn.2018.11.008. Epub 2018 Nov 20.


Potentials of Cellular Reprogramming as a Novel Strategy for Neuroregeneration.

Fang L, El Wazan L, Tan C, Nguyen T, Hung SSC, Hewitt AW, Wong RCB.

Front Cell Neurosci. 2018 Nov 30;12:460. doi: 10.3389/fncel.2018.00460. eCollection 2018. Review. Erratum in: Front Cell Neurosci. 2019 May 03;13:147.


Innovative Strain Sensing for Detection of Exterior Wall Tile Lesion: Smart Skin Sensory System.

Chang CY, Hung SS, Liu LH, Lin CP.

Materials (Basel). 2018 Nov 30;11(12). pii: E2432. doi: 10.3390/ma11122432.


Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis.

De Smit E, Lukowski SW, Anderson L, Senabouth A, Dauyey K, Song S, Wyse B, Wheeler L, Chen CY, Cao K, Wong Ten Yuen A, Shuey N, Clarke L, Lopez Sanchez I, Hung SSC, Pébay A, Mackey DA, Brown MA, Hewitt AW, Powell JE.

BMC Med Genomics. 2018 Jul 23;11(1):61. doi: 10.1186/s12920-018-0376-4.


Recent advances in sturgeon nutrition.

Hung SSO.

Anim Nutr. 2017 Sep;3(3):191-204. doi: 10.1016/j.aninu.2017.05.005. Epub 2017 May 30. Review.


Electroacupuncture plus standard of care for managing refractory functional dyspepsia: protocol of a pragmatic trial with economic evaluation.

Chung VCH, Wong CHL, Ching JYL, Sun WZ, Ju YL, Hung SS, Lin WL, Leung KC, Wong SYS, Wu JCY.

BMJ Open. 2018 Mar 27;8(3):e018430. doi: 10.1136/bmjopen-2017-018430.


Somatic IL4R mutations in primary mediastinal large B-cell lymphoma lead to constitutive JAK-STAT signaling activation.

Viganò E, Gunawardana J, Mottok A, Van Tol T, Mak K, Chan FC, Chong L, Chavez E, Woolcock B, Takata K, Twa D, Shulha HP, Telenius A, Kutovaya O, Hung SS, Healy S, Ben-Neriah S, Leroy K, Gaulard P, Diepstra A, Kridel R, Savage KJ, Rimsza L, Gascoyne R, Steidl C.

Blood. 2018 May 3;131(18):2036-2046. doi: 10.1182/blood-2017-09-808907. Epub 2018 Feb 21.


Assessment of Capture and Amplicon-Based Approaches for the Development of a Targeted Next-Generation Sequencing Pipeline to Personalize Lymphoma Management.

Hung SS, Meissner B, Chavez EA, Ben-Neriah S, Ennishi D, Jones MR, Shulha HP, Chan FC, Boyle M, Kridel R, Gascoyne RD, Mungall AJ, Marra MA, Scott DW, Connors JM, Steidl C.

J Mol Diagn. 2018 Mar;20(2):203-214. doi: 10.1016/j.jmoldx.2017.11.010. Epub 2018 Feb 8.


Methods for In Vivo CRISPR/Cas Editing of the Adult Murine Retina.

Hung SS, Li F, Wang JH, King AE, Bui BV, Liu GS, Hewitt AW.

Methods Mol Biol. 2018;1715:113-133. doi: 10.1007/978-1-4939-7522-8_9.


Generation of a human induced pluripotent stem cell line CERAi001-A-6 using episomal vectors.

Wong RCB, Hung SS, Jackson S, Singh V, Khan S, Liang HH, Kearns LS, Nguyen T, Conquest A, Daniszewski M, Hewitt AW, Pébay A.

Stem Cell Res. 2017 Jul;22:13-15. doi: 10.1016/j.scr.2017.05.007. Epub 2017 May 19.


Drusen in patient-derived hiPSC-RPE models of macular dystrophies.

Galloway CA, Dalvi S, Hung SSC, MacDonald LA, Latchney LR, Wong RCB, Guymer RH, Mackey DA, Williams DS, Chung MM, Gamm DM, Pébay A, Hewitt AW, Singh R.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8214-E8223. doi: 10.1073/pnas.1710430114. Epub 2017 Sep 6.


Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy.

Wong RCB, Lim SY, Hung SSC, Jackson S, Khan S, Van Bergen NJ, De Smit E, Liang HH, Kearns LS, Clarke L, Mackey DA, Hewitt AW, Trounce IA, Pébay A.

Aging (Albany NY). 2017 Apr;9(4):1341-1350. doi: 10.18632/aging.101231.


Development of a Modular Automated System for Maintenance and Differentiation of Adherent Human Pluripotent Stem Cells.

Crombie DE, Daniszewski M, Liang HH, Kulkarni T, Li F, Lidgerwood GE, Conquest A, Hernández D, Hung SS, Gill KP, De Smit E, Kearns LS, Clarke L, Sluch VM, Chamling X, Zack DJ, Wong RCB, Hewitt AW, Pébay A.

SLAS Discov. 2017 Sep;22(8):1016-1025. doi: 10.1177/2472555217696797. Epub 2017 Mar 13.


Development of growth rate, body lipid, moisture, and energy models for white sturgeon (Acipenser transmontanus) fed at various feeding rates.

Lee S, Sonmez O, Hung SSO, Fadel JG.

Anim Nutr. 2017 Mar;3(1):46-60. doi: 10.1016/j.aninu.2016.10.005. Epub 2016 Nov 9.


Drug discovery using induced pluripotent stem cell models of neurodegenerative and ocular diseases.

Hung SSC, Khan S, Lo CY, Hewitt AW, Wong RCB.

Pharmacol Ther. 2017 Sep;177:32-43. doi: 10.1016/j.pharmthera.2017.02.026. Epub 2017 Feb 14. Review.


Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription.

Hung SS, Lesmana A, Peck A, Lee R, Tchoubrieva E, Hannan KM, Lin J, Sheppard KE, Jastrzebski K, Quinn LM, Rothblum LI, Pearson RB, Hannan RD, Sanij E.

Gene. 2017 May 15;612:36-48. doi: 10.1016/j.gene.2016.12.015. Epub 2016 Dec 15.


A Portable Array-Type Optical Fiber Sensing Instrument for Real-Time Gas Detection.

Hung SS, Chang HC, Chang IN.

Sensors (Basel). 2016 Dec 8;16(12). pii: E2087.


Binary colloidal crystals (BCCs) as a feeder-free system to generate human induced pluripotent stem cells (hiPSCs).

Wang PY, Hung SS, Thissen H, Kingshott P, Wong RC.

Sci Rep. 2016 Nov 11;6:36845. doi: 10.1038/srep36845.


The use of induced pluripotent stem cells for studying and treating optic neuropathies.

Khan S, Hung SS, Wong RC.

Curr Opin Organ Transplant. 2016 Oct;21(5):484-9. doi: 10.1097/MOT.0000000000000348. Review.


Enriched retinal ganglion cells derived from human embryonic stem cells.

Gill KP, Hung SS, Sharov A, Lo CY, Needham K, Lidgerwood GE, Jackson S, Crombie DE, Nayagam BA, Cook AL, Hewitt AW, Pébay A, Wong RC.

Sci Rep. 2016 Aug 10;6:30552. doi: 10.1038/srep30552.


AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo.

Hung SS, Chrysostomou V, Li F, Lim JK, Wang JH, Powell JE, Tu L, Daniszewski M, Lo C, Wong RC, Crowston JG, Pébay A, King AE, Bui BV, Liu GS, Hewitt AW.

Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):3470-6. doi: 10.1167/iovs.16-19316.


Genome engineering in ophthalmology: Application of CRISPR/Cas to the treatment of eye disease.

Hung SSC, McCaughey T, Swann O, Pébay A, Hewitt AW.

Prog Retin Eye Res. 2016 Jul;53:1-20. doi: 10.1016/j.preteyeres.2016.05.001. Epub 2016 May 13. Review.


Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells.

Hung SS, Van Bergen NJ, Jackson S, Liang H, Mackey DA, Hernández D, Lim SY, Hewitt AW, Trounce I, Pébay A, Wong RC.

Aging (Albany NY). 2016 May;8(5):945-57. doi: 10.18632/aging.100950.


Effects of feed restriction on the upper temperature tolerance and heat shock response in juvenile green and white sturgeon.

Lee S, Hung SS, Fangue NA, Haller L, Verhille CE, Zhao J, Todgham AE.

Comp Biochem Physiol A Mol Integr Physiol. 2016 Aug;198:87-95. doi: 10.1016/j.cbpa.2016.04.016. Epub 2016 Apr 16.


Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell Lung Cancer Cells In Vitro.

Leung AW, Hung SS, Backstrom I, Ricaurte D, Kwok B, Poon S, McKinney S, Segovia R, Rawji J, Qadir MA, Aparicio S, Stirling PC, Steidl C, Bally MB.

PLoS One. 2016 Mar 3;11(3):e0150675. doi: 10.1371/journal.pone.0150675. eCollection 2016.


Responses of heat shock protein 70 and caspase-3/7 to dietary selenomethionine in juvenile white sturgeon.

Wang W, Lee S, Hung SSO, Deng DF.

Anim Nutr. 2016 Mar;2(1):45-50. doi: 10.1016/j.aninu.2016.02.001. Epub 2016 Mar 15.


Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells.

Hernández D, Millard R, Sivakumaran P, Wong RC, Crombie DE, Hewitt AW, Liang H, Hung SS, Pébay A, Shepherd RK, Dusting GJ, Lim SY.

Stem Cells Int. 2016;2016:1718041. doi: 10.1155/2016/1718041. Epub 2015 Dec 14.


Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes.

Hung SS, Pébay A, Wong RC.

J Vis Exp. 2015 Aug 20;(102):e53174. doi: 10.3791/53174.


Effects of feed restriction on salinity tolerance in white sturgeon (Acipenser transmontanus).

Lee S, Fadel JG, Haller LY, Verhille CE, Fangue NA, Hung SS.

Comp Biochem Physiol A Mol Integr Physiol. 2015 Oct;188:156-67. doi: 10.1016/j.cbpa.2015.06.027. Epub 2015 Jun 27.


Impact of nutrition and salinity changes on biological performances of green and white sturgeon.

Vaz PG, Kebreab E, Hung SS, Fadel JG, Lee S, Fangue NA.

PLoS One. 2015 Apr 1;10(4):e0122029. doi: 10.1371/journal.pone.0122029. eCollection 2015.


Systems-based analysis of the Sarcocystis neurona genome identifies pathways that contribute to a heteroxenous life cycle.

Blazejewski T, Nursimulu N, Pszenny V, Dangoudoubiyam S, Namasivayam S, Chiasson MA, Chessman K, Tonkin M, Swapna LS, Hung SS, Bridgers J, Ricklefs SM, Boulanger MJ, Dubey JP, Porcella SF, Kissinger JC, Howe DK, Grigg ME, Parkinson J.

MBio. 2015 Feb 10;6(1). pii: e02445-14. doi: 10.1128/mBio.02445-14.


Effect of nutritional status on the osmoregulation of green sturgeon (Acipenser medirostris).

Haller LY, Hung SS, Lee S, Fadel JG, Lee JH, McEnroe M, Fangue NA.

Physiol Biochem Zool. 2015 Jan-Feb;88(1):22-42. doi: 10.1086/679519. Epub 2014 Dec 18.


Endovascular intervention in Taiwanese patients with critical limb ischemia: patient outcomes in 333 consecutive limb procedures with a 3-year follow-up.

Huang HL, Chou HH, Wu TY, Chang SH, Tsai YJ, Hung SS, Lu CT, Cheng ST, Yeh KH, Chang HC.

J Formos Med Assoc. 2014 Oct;113(10):688-95. doi: 10.1016/j.jfma.2012.10.022. Epub 2013 Jan 18.


Maintaining tissue selenium species distribution as a potential defense mechanism against methylmercury toxicity in juvenile white sturgeon (Acipenser transmontanus).

Huang SS, Hung SS, Chan HM.

Aquat Toxicol. 2014 Nov;156:88-95. doi: 10.1016/j.aquatox.2014.08.004. Epub 2014 Aug 17.


Genomic analysis of the causative agents of coccidiosis in domestic chickens.

Reid AJ, Blake DP, Ansari HR, Billington K, Browne HP, Bryant J, Dunn M, Hung SS, Kawahara F, Miranda-Saavedra D, Malas TB, Mourier T, Naghra H, Nair M, Otto TD, Rawlings ND, Rivailler P, Sanchez-Flores A, Sanders M, Subramaniam C, Tay YL, Woo Y, Wu X, Barrell B, Dear PH, Doerig C, Gruber A, Ivens AC, Parkinson J, Rajandream MA, Shirley MW, Wan KL, Berriman M, Tomley FM, Pain A.

Genome Res. 2014 Oct;24(10):1676-85. doi: 10.1101/gr.168955.113. Epub 2014 Jul 11.


Efficient generation of integration-free human induced pluripotent stem cells from keratinocytes by simple transfection of episomal vectors.

Piao Y, Hung SS, Lim SY, Wong RC, Ko MS.

Stem Cells Transl Med. 2014 Jul;3(7):787-91. doi: 10.5966/sctm.2013-0036. Epub 2014 Jun 5.


Effect of dietary selenomethionine on growth performance, tissue burden, and histopathology in green and white sturgeon.

De Riu N, Lee JW, Huang SS, Moniello G, Hung SS.

Aquat Toxicol. 2014 Mar;148:65-73. doi: 10.1016/j.aquatox.2013.12.030. Epub 2014 Jan 6.


Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii.

Song C, Chiasson MA, Nursimulu N, Hung SS, Wasmuth J, Grigg ME, Parkinson J.

Mol Syst Biol. 2013 Nov 19;9:708. doi: 10.1038/msb.2013.62.


Coordinated control of bone cutting for a CT-free navigation robotic system in total knee arthroplasty.

Yen PL, Chu YJ, Hsu SW, Wang JH, Hung SS.

Int J Med Robot. 2014 Jun;10(2):180-6. doi: 10.1002/rcs.1526. Epub 2013 Aug 19.


Repression of global protein synthesis by Eif1a-like genes that are expressed specifically in the two-cell embryos and the transient Zscan4-positive state of embryonic stem cells.

Hung SS, Wong RC, Sharov AA, Nakatake Y, Yu H, Ko MS.

DNA Res. 2013 Aug;20(4):391-402. doi: 10.1093/dnares/dst018. Epub 2013 May 5.


The genomes of four tapeworm species reveal adaptations to parasitism.

Tsai IJ, Zarowiecki M, Holroyd N, Garciarrubio A, Sánchez-Flores A, Brooks KL, Tracey A, Bobes RJ, Fragoso G, Sciutto E, Aslett M, Beasley H, Bennett HM, Cai X, Camicia F, Clark R, Cucher M, De Silva N, Day TA, Deplazes P, Estrada K, Fernández C, Holland PWH, Hou J, Hu S, Huckvale T, Hung SS, Kamenetzky L, Keane JA, Kiss F, Koziol U, Lambert O, Liu K, Luo X, Luo Y, Macchiaroli N, Nichol S, Paps J, Parkinson J, Pouchkina-Stantcheva N, Riddiford N, Rosenzvit M, Salinas G, Wasmuth JD, Zamanian M, Zheng Y; Taenia solium Genome Consortium, Cai J, Soberón X, Olson PD, Laclette JP, Brehm K, Berriman M.

Nature. 2013 Apr 4;496(7443):57-63. doi: 10.1038/nature12031. Epub 2013 Mar 13.


The interactive effects of selenomethionine and methylmercury on their absorption, disposition, and elimination in juvenile white sturgeon.

Huang SS, Strathe AB, Fadel JG, Johnson ML, Lin P, Liu TY, Hung SS.

Aquat Toxicol. 2013 Jan 15;126:274-82. doi: 10.1016/j.aquatox.2012.09.018. Epub 2012 Sep 28.


Analysis of building envelope insulation performance utilizing integrated temperature and humidity sensors.

Hung SS, Chang CY, Hsu CJ, Chen SW.

Sensors (Basel). 2012;12(7):8987-9005. Epub 2012 Jun 29.

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