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Items: 1 to 50 of 477

1.

Evaluation of empiric beta-lactam susceptibility prediction among Enterobacteriaceae by molecular beta-lactamase gene testing.

Spafford K, MacVane S, Humphries R.

J Clin Microbiol. 2019 Jul 24. pii: JCM.00674-19. doi: 10.1128/JCM.00674-19. [Epub ahead of print]

PMID:
31340995
2.

Characterization of aerosols over the Great Barrier Reef: The influence of transported continental sources.

Chen Z, Schofield R, Rayner P, Zhang T, Liu C, Vincent C, Fiddes S, Ryan RG, Alroe J, Ristovski ZD, Humphries RS, Keywood MD, Ward J, Paton-Walsh C, Naylor T, Shu X.

Sci Total Environ. 2019 Jul 2;690:426-437. doi: 10.1016/j.scitotenv.2019.07.007. [Epub ahead of print]

PMID:
31299575
3.

The infrared reflex: a potential new method for congenital cataract screening.

Duret A, Humphries R, Ramanujam S, Te Water Naudé A, Reid C, Allen LE.

Eye (Lond). 2019 Jul 2. doi: 10.1038/s41433-019-0509-9. [Epub ahead of print]

PMID:
31267092
4.

Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia.

Kusakabe M, Sun AC, Tyshchenko K, Wong R, Nanda A, Shanna C, Gusscott S, Chavez EA, Lorzadeh A, Zhu A, Hill A, Hung S, Brown S, Babaian A, Wang X, Holt RA, Steidl C, Karsan A, Humphries RK, Eaves CJ, Hirst M, Weng AP.

Nat Commun. 2019 Jul 2;10(1):2913. doi: 10.1038/s41467-019-10510-8.

5.

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis.

Wilson MR, Sample HA, Zorn KC, Arevalo S, Yu G, Neuhaus J, Federman S, Stryke D, Briggs B, Langelier C, Berger A, Douglas V, Josephson SA, Chow FC, Fulton BD, DeRisi JL, Gelfand JM, Naccache SN, Bender J, Dien Bard J, Murkey J, Carlson M, Vespa PM, Vijayan T, Allyn PR, Campeau S, Humphries RM, Klausner JD, Ganzon CD, Memar F, Ocampo NA, Zimmermann LL, Cohen SH, Polage CR, DeBiasi RL, Haller B, Dallas R, Maron G, Hayden R, Messacar K, Dominguez SR, Miller S, Chiu CY.

N Engl J Med. 2019 Jun 13;380(24):2327-2340. doi: 10.1056/NEJMoa1803396.

6.

Candida auris: An Emerging Yeast Pathogen Posing Distinct Challenges for Laboratory Diagnostics, Treatment, and Infection Prevention.

Hata DJ, Humphries R, Lockhart SR; College of American Pathologists Microbiology Committee.

Arch Pathol Lab Med. 2019 Jun 6. doi: 10.5858/arpa.2018-0508-RA. [Epub ahead of print]

PMID:
31169997
7.

A Laboratory Medicine Best Practices Systematic Review and Meta-analysis of Nucleic Acid Amplification Tests (NAATs) and Algorithms Including NAATs for the Diagnosis of Clostridioides (Clostridium) difficile in Adults.

Kraft CS, Parrott JS, Cornish NE, Rubinstein ML, Weissfeld AS, McNult P, Nachamkin I, Humphries RM, Kirn TJ, Dien Bard J, Lutgring JD, Gullett JC, Bittencourt CE, Benson S, Bobenchik AM, Sautter RL, Baselski V, Atlas MC, Marlowe EM, Miller NS, Fischer M, Richter SS, Gilligan P, Snyder JW.

Clin Microbiol Rev. 2019 May 29;32(3). pii: e00032-18. doi: 10.1128/CMR.00032-18. Print 2019 Jun 19.

8.

EUCAST disc diffusion criteria for the detection of mecA-Mediated β-lactam resistance in Staphylococcus pseudintermedius: oxacillin versus cefoxitin.

Skov R, Varga A, Matuschek E, Åhman J, Bemis D, Bengtsson B, Sunde M, Humphries R, Westblade L, Guardabassi L, Kahlmeter G.

Clin Microbiol Infect. 2019 May 17. pii: S1198-743X(19)30215-0. doi: 10.1016/j.cmi.2019.05.002. [Epub ahead of print]

PMID:
31108230
9.

Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo.

Jyotsana N, Sharma A, Chaturvedi A, Budida R, Scherr M, Kuchenbauer F, Lindner R, Noyan F, Sühs KW, Stangel M, Grote-Koska D, Brand K, Vornlocher HP, Eder M, Thol F, Ganser A, Humphries RK, Ramsay E, Cullis P, Heuser M.

Ann Hematol. 2019 Aug;98(8):1905-1918. doi: 10.1007/s00277-019-03713-y. Epub 2019 May 18.

PMID:
31104089
10.

The New, New Daptomycin Breakpoint for Enterococcus spp.

Humphries RM.

J Clin Microbiol. 2019 Jun 25;57(7). pii: e00600-19. doi: 10.1128/JCM.00600-19. Print 2019 Jul.

PMID:
31092593
11.

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML.

Garg S, Reyes-Palomares A, He L, Bergeron A, Lavallée VP, Lemieux S, Gendron P, Rohde C, Xia J, Jagdhane P, Müller-Tidow C, Lipka DB, Imren S, Humphries RK, Waskow C, Vick B, Jeremias I, Richard-Carpentier G, Hébert J, Sauvageau G, Zaugg JB, Barabé F, Pabst C.

Blood. 2019 Jul 18;134(3):263-276. doi: 10.1182/blood.2018862383. Epub 2019 May 10.

PMID:
31076446
12.

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling.

Coulombe P, Paliouras GN, Clayton A, Hussainkhel A, Fuller M, Jovanovic V, Dauphinee S, Umlandt P, Xiang P, Kyle AH, Minchinton AI, Humphries RK, Hoodless PA, Parker JDK, Wright JL, Karsan A.

Cell Rep. 2019 May 7;27(6):1769-1780.e4. doi: 10.1016/j.celrep.2019.04.039.

13.

CIM City: the Game Continues for a Better Carbapenemase Test.

Humphries RM.

J Clin Microbiol. 2019 Jun 25;57(7). pii: e00353-19. doi: 10.1128/JCM.00353-19. Print 2019 Jul.

PMID:
30995992
14.

Understanding and Addressing CLSI Breakpoint Revisions: a Primer for Clinical Laboratories.

Humphries RM, Abbott AN, Hindler JA.

J Clin Microbiol. 2019 May 24;57(6). pii: e00203-19. doi: 10.1128/JCM.00203-19. Print 2019 Jun. Review.

PMID:
30971460
15.

Letter to the Editor.

Humphries R, Spafford K.

Clin Infect Dis. 2019 Apr 6. pii: ciz224. doi: 10.1093/cid/ciz224. [Epub ahead of print] No abstract available.

PMID:
30953052
16.

Risk Factors for Development of Carbapenem Resistance Among Gram-Negative Rods.

Richter SE, Miller L, Needleman J, Uslan DZ, Bell D, Watson K, Humphries R, McKinnell JA.

Open Forum Infect Dis. 2019 Jan 23;6(3):ofz027. doi: 10.1093/ofid/ofz027. eCollection 2019 Mar.

17.

Ceftazidime/avibactam resistance associated with L169P mutation in the omega loop of KPC-2.

Hemarajata P, Humphries RM.

J Antimicrob Chemother. 2019 Feb 7. doi: 10.1093/jac/dkz026. [Epub ahead of print]

PMID:
30753572
18.

A multisite implementation of a real-time polymerase chain reaction assay to predict ciprofloxacin susceptibility in Neisseria gonorrhoeae.

Ellis O, Hemarajata P, Shahkolahi A, Masinde G, Buchs K, Humphries RM, Klausner JD.

Diagn Microbiol Infect Dis. 2019 Jul;94(3):213-217. doi: 10.1016/j.diagmicrobio.2018.12.018. Epub 2019 Jan 14.

PMID:
30723007
19.

Effective implementation of the Accelerate Pheno™ system for positive blood cultures.

Humphries R, Di Martino T.

J Antimicrob Chemother. 2019 Jan 1;74(Supplement_1):i40-i43. doi: 10.1093/jac/dky534.

20.

Evaluation of the Accelerate Pheno System for Identification of Acinetobacter Clinical Isolates and Minocycline Susceptibility Testing.

Bowler SL, Towne JW, Humphries RM, Doi Y.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e01711-18. doi: 10.1128/JCM.01711-18. Print 2019 Mar.

PMID:
30651391
21.

Public Health Efforts Can Impact Adoption of Current Susceptibility Breakpoints, but Closer Attention from Regulatory Bodies Is Needed.

McKinnell JA, Bhaurla S, Marquez-Sung P, Pucci A, Baron M, Kamali T, Bugante J, Schwartz B, Balter S, Terashita D, Butler-Wu S, Gunzenhauser J, Hindler J, Humphries RM.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e01488-18. doi: 10.1128/JCM.01488-18. Print 2019 Mar.

PMID:
30567751
22.

Evaluation of Ciprofloxacin and Levofloxacin Disk Diffusion and Etest Using the 2019 Enterobacteriaceae CLSI Breakpoints.

Humphries RM, Hindler JA, Shaffer K, Campeau SA.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e01797-18. doi: 10.1128/JCM.01797-18. Print 2019 Mar.

PMID:
30567744
23.

Performance of ceftazidime/avibactam susceptibility testing methods against clinically relevant Gram-negative organisms.

Wenzler E, Lee M, Wu TJ, Meyer KA, Shields RK, Nguyen MH, Clancy CJ, Humphries RM, Harrington AT.

J Antimicrob Chemother. 2019 Mar 1;74(3):633-638. doi: 10.1093/jac/dky483.

PMID:
30534964
24.

Two-Site Evaluation of the Colistin Broth Disk Elution Test To Determine Colistin In Vitro Activity against Gram-Negative Bacilli.

Simner PJ, Bergman Y, Trejo M, Roberts AA, Marayan R, Tekle T, Campeau S, Kazmi AQ, Bell DT, Lewis S, Tamma PD, Humphries R, Hindler JA.

J Clin Microbiol. 2019 Jan 30;57(2). pii: e01163-18. doi: 10.1128/JCM.01163-18. Print 2019 Feb.

25.

Fluoroquinolone Prophylaxis Selects for Meropenem-nonsusceptible Pseudomonas aeruginosa in Patients With Hematologic Malignancies and Hematopoietic Cell Transplant Recipients.

Hakki M, Humphries RM, Hemarajata P, Tallman GB, Shields RK, Mettus RT, Doi Y, Lewis JS.

Clin Infect Dis. 2019 May 30;68(12):2045-2052. doi: 10.1093/cid/ciy825.

PMID:
30256922
26.

The Frequency of Discordant Gyrase A Genotypes Among Cases of Multiple Neisseria gonorrhoeae Infections at Different Anatomic Sites.

Allan-Blitz LT, Ellis OL, Bolan R, Hemarajata P, Humphries RM, Shahkolahi A, McGrath M, Klausner JD.

Sex Transm Dis. 2019 Jan;46(1):e3-e4. doi: 10.1097/OLQ.0000000000000912.

PMID:
30216232
27.

Practical methods for effective vancomycin-resistant enterococci (VRE) surveillance: experience in a liver transplant surgical intensive care unit.

Linfield RY, Campeau S, Injean P, Gregson A, Kaldas F, Rubin Z, Kim T, Kunz D, Chan A, Lee DJ, Humphries RM, McKinnell JA.

Infect Control Hosp Epidemiol. 2018 Oct;39(10):1178-1182. doi: 10.1017/ice.2018.178. Epub 2018 Sep 4.

PMID:
30178725
28.

UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells.

Ngom M, Imren S, Maetzig T, Adair JE, Knapp DJHF, Chagraoui J, Fares I, Bordeleau ME, Sauvageau G, Leboulch P, Eaves C, Humphries RK.

Mol Ther Methods Clin Dev. 2018 Jul 5;10:156-164. doi: 10.1016/j.omtm.2018.06.009. eCollection 2018 Sep 21.

29.

Pharmacodynamics of Daptomycin against Enterococcus faecium and Enterococcus faecalis in the Murine Thigh Infection Model.

Kidd JM, Abdelraouf K, Asempa TE, Humphries RM, Nicolau DP.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e00506-18. doi: 10.1128/AAC.00506-18. Print 2018 Oct.

30.

Risk Factors for Colistin Resistance among Gram-Negative Rods and Klebsiella pneumoniae Isolates.

Richter SE, Miller L, Uslan DZ, Bell D, Watson K, Humphries R, McKinnell JA.

J Clin Microbiol. 2018 Aug 27;56(9). pii: e00149-18. doi: 10.1128/JCM.00149-18. Print 2018 Sep.

31.

Multicenter Evaluation of the Etest Gradient Diffusion Method for Ceftolozane-Tazobactam Susceptibility Testing of Enterobacteriaceae and Pseudomonas aeruginosa.

Bailey AL, Armstrong T, Dwivedi HP, Denys GA, Hindler J, Campeau S, Traczewski M, Humphries R, Burnham CA.

J Clin Microbiol. 2018 Aug 27;56(9). pii: e00717-18. doi: 10.1128/JCM.00717-18. Print 2018 Sep.

32.

Variability of Daptomycin MIC Values for Enterococcus faecium When Measured by Reference Broth Microdilution and Gradient Diffusion Tests.

Campeau SA, Schuetz AN, Kohner P, Arias CA, Hemarajata P, Bard JD, Humphries RM.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00745-18. doi: 10.1128/AAC.00745-18. Print 2018 Sep.

33.

Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential.

Knapp DJHF, Hammond CA, Hui T, van Loenhout MTJ, Wang F, Aghaeepour N, Miller PH, Moksa M, Rabu GM, Beer PA, Pellacani D, Humphries RK, Hansen C, Hirst M, Eaves CJ.

Nat Cell Biol. 2018 Jun;20(6):710-720. doi: 10.1038/s41556-018-0104-5. Epub 2018 May 25.

PMID:
29802403
34.

Twenty-first Century Cures Act and Antimicrobial Susceptibility Testing: Clinical Implications in the Era of Multidrug Resistance.

Humphries RM, Hindler J, Jane Ferraro M, Mathers A.

Clin Infect Dis. 2018 Sep 14;67(7):1132-1138. doi: 10.1093/cid/ciy432.

PMID:
29796616
35.

How to better monitor and clean irregular surfaces in operating rooms: Insights gained by using both ATP luminescence and RODAC assays.

Ellis O, Godwin H, David M, Morse DJ, Humphries R, Uslan DZ.

Am J Infect Control. 2018 Aug;46(8):906-912. doi: 10.1016/j.ajic.2018.03.024. Epub 2018 May 18.

PMID:
29779688
36.

The Continued Value of Disk Diffusion for Assessing Antimicrobial Susceptibility in Clinical Laboratories: Report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group.

Humphries RM, Kircher S, Ferrell A, Krause KM, Malherbe R, Hsiung A, Burnham CA.

J Clin Microbiol. 2018 Jul 26;56(8). pii: e00437-18. doi: 10.1128/JCM.00437-18. Print 2018 Aug. Review.

37.

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients.

Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y.

Infect Immun. 2018 Jun 21;86(7). pii: e00253-18. doi: 10.1128/IAI.00253-18. Print 2018 Jul.

38.

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells.

Chang YL, Rossetti M, Vlamakis H, Casero D, Sunga G, Harre N, Miller S, Humphries R, Stappenbeck T, Simpson KW, Sartor RB, Wu G, Lewis J, Bushman F, McGovern DPB, Salzman N, Borneman J, Xavier R, Huttenhower C, Braun J.

Mucosal Immunol. 2019 Mar;12(2):457-467. doi: 10.1038/s41385-018-0022-7. Epub 2018 Apr 25.

39.

Duodenoscope-Related Outbreak of a Carbapenem-Resistant Klebsiella pneumoniae Identified Using Advanced Molecular Diagnostics.

Humphries RM, Yang S, Kim S, Muthusamy VR, Russell D, Trout AM, Zaroda T, Cheng QJ, Aldrovandi G, Uslan DZ, Hemarajata P, Rubin ZA.

Clin Infect Dis. 2017 Oct 1;65(7):1159-1166. doi: 10.1093/cid/cix527.

PMID:
29579235
40.

Selection of hyperproduction of AmpC and SME-1 in a carbapenem-resistant Serratia marcescens isolate during antibiotic therapy.

Hemarajata P, Amick T, Yang S, Gregson A, Holzmeyer C, Bush K, Humphries RM.

J Antimicrob Chemother. 2018 May 1;73(5):1256-1262. doi: 10.1093/jac/dky028.

PMID:
29471486
41.

Ciprofloxacin May be Efficacious in Treating Wild-Type Gyrase A Genotype Neisseria gonorrhoeae Infections.

Allan-Blitz LT, Hemarajata P, Humphries RM, Kimble M, Elias S, Klausner JD.

Sex Transm Dis. 2018 Apr;45(4):e18. doi: 10.1097/OLQ.0000000000000758. No abstract available.

42.

Impact of 21st Century Cures Act on Breakpoints and Commercial Antimicrobial Susceptibility Test Systems: Progress and Pitfalls.

Humphries RM, Ferraro MJ, Hindler JA.

J Clin Microbiol. 2018 Apr 25;56(5). pii: e00139-18. doi: 10.1128/JCM.00139-18. Print 2018 May. Review.

43.

Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia.

Bhayadia R, Krowiorz K, Haetscher N, Jammal R, Emmrich S, Obulkasim A, Fiedler J, Schwarzer A, Rouhi A, Heuser M, Wingert S, Bothur S, Döhner K, Mätzig T, Ng M, Reinhardt D, Döhner H, Zwaan CM, van den Heuvel Eibrink M, Heckl D, Fornerod M, Thum T, Humphries RK, Rieger MA, Kuchenbauer F, Klusmann JH.

J Clin Oncol. 2018 Apr 1;36(10):1007-1016. doi: 10.1200/JCO.2017.75.2204. Epub 2018 Feb 12.

PMID:
29432078
44.

CLSI Methods Development and Standardization Working Group Best Practices for Evaluation of Antimicrobial Susceptibility Tests.

Humphries RM, Ambler J, Mitchell SL, Castanheira M, Dingle T, Hindler JA, Koeth L, Sei K; CLSI Methods Development and Standardization Working Group of the Subcommittee on Antimicrobial Susceptibility Testing.

J Clin Microbiol. 2018 Mar 26;56(4). pii: e01934-17. doi: 10.1128/JCM.01934-17. Print 2018 Apr. Review.

45.

A Cost Analysis of Gyrase A Testing and Targeted Ciprofloxacin Therapy Versus Recommended 2-Drug Therapy for Neisseria gonorrhoeae Infection.

Allan-Blitz LT, Hemarajata P, Humphries RM, Wynn A, Segura ER, Klausner JD.

Sex Transm Dis. 2018 Feb;45(2):87-91. doi: 10.1097/OLQ.0000000000000698.

PMID:
29329176
46.

Multicenter Evaluation of the Accelerate PhenoTest BC Kit for Rapid Identification and Phenotypic Antimicrobial Susceptibility Testing Using Morphokinetic Cellular Analysis.

Pancholi P, Carroll KC, Buchan BW, Chan RC, Dhiman N, Ford B, Granato PA, Harrington AT, Hernandez DR, Humphries RM, Jindra MR, Ledeboer NA, Miller SA, Mochon AB, Morgan MA, Patel R, Schreckenberger PC, Stamper PD, Simner PJ, Tucci NE, Zimmerman C, Wolk DM.

J Clin Microbiol. 2018 Mar 26;56(4). pii: e01329-17. doi: 10.1128/JCM.01329-17. Print 2018 Apr.

47.

Direct-from-Blood-Culture Disk Diffusion To Determine Antimicrobial Susceptibility of Gram-Negative Bacteria: Preliminary Report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group.

Chandrasekaran S, Abbott A, Campeau S, Zimmer BL, Weinstein M, Thrupp L, Hejna J, Walker L, Ammann T, Kirn T, Patel R, Humphries RM.

J Clin Microbiol. 2018 Feb 22;56(3). pii: e01678-17. doi: 10.1128/JCM.01678-17. Print 2018 Mar.

48.

A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1.

Xiang P, Wei W, Hofs N, Clemans-Gibbon J, Maetzig T, Lai CK, Dhillon I, May C, Ruschmann J, Schneider E, Rosten P, Hu K, Kuchenbauer F, Hoodless PA, Humphries RK.

Blood Adv. 2017 Nov 7;1(24):2225-2235. doi: 10.1182/bloodadvances.2017010355. eCollection 2017 Nov 14.

49.

Micro-ribonucleic acid-155 is a direct target of Meis1, but not a driver in acute myeloid leukemia.

Schneider E, Staffas A, Röhner L, Malmberg ED, Ashouri A, Krowiorz K, Pochert N, Miller C, Wei SY, Arabanian L, Buske C, Döhner H, Bullinger L, Fogelstrand L, Heuser M, Döhner K, Xiang P, Ruschmann J, Petriv OI, Heravi-Moussavi A, Hansen CL, Hirst M, Humphries RK, Rouhi A, Palmqvist L, Kuchenbauer F.

Haematologica. 2018 Feb;103(2):246-255. doi: 10.3324/haematol.2017.177485. Epub 2017 Dec 7.

50.

Performance of Ceftolozane-Tazobactam Etest, MIC Test Strips, and Disk Diffusion Compared to Reference Broth Microdilution for β-Lactam-Resistant Pseudomonas aeruginosa Isolates.

Humphries RM, Hindler JA, Magnano P, Wong-Beringer A, Tibbetts R, Miller SA.

J Clin Microbiol. 2018 Feb 22;56(3). pii: e01633-17. doi: 10.1128/JCM.01633-17. Print 2018 Mar.

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