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Items: 1 to 50 of 113

1.

Sexually selected infanticide by male red squirrels in advance of a mast year.

Haines JA, Coltman DW, Dantzer B, Gorrell JC, Humphries MM, Lane JE, McAdam AG, Boutin S.

Ecology. 2018 May;99(5):1242-1244. doi: 10.1002/ecy.2158. Epub 2018 Mar 15. No abstract available.

PMID:
29543323
2.

Phenological shifts in North American red squirrels: disentangling the roles of phenotypic plasticity and microevolution.

Lane JE, McAdam AG, McFarlane SE, Williams CT, Humphries MM, Coltman DW, Gorrell JC, Boutin S.

J Evol Biol. 2018 Jun;31(6):810-821. doi: 10.1111/jeb.13263. Epub 2018 Apr 30.

PMID:
29518280
3.

Seasonal, spatial, and maternal effects on gut microbiome in wild red squirrels.

Ren T, Boutin S, Humphries MM, Dantzer B, Gorrell JC, Coltman DW, McAdam AG, Wu M.

Microbiome. 2017 Dec 21;5(1):163. doi: 10.1186/s40168-017-0382-3.

4.

Understanding Evolutionary Impacts of Seasonality: An Introduction to the Symposium.

Williams CM, Ragland GJ, Betini G, Buckley LB, Cheviron ZA, Donohue K, Hereford J, Humphries MM, Lisovski S, Marshall KE, Schmidt PS, Sheldon KS, Varpe Ø, Visser ME.

Integr Comp Biol. 2017 Nov 1;57(5):921-933. doi: 10.1093/icb/icx122.

PMID:
29045649
5.

To Everything There Is a Season: Summer-to-Winter Food Webs and the Functional Traits of Keystone Species.

Humphries MM, Studd EK, Menzies AK, Boutin S.

Integr Comp Biol. 2017 Nov 1;57(5):961-976. doi: 10.1093/icb/icx119. Review.

PMID:
29040576
6.

Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia.

Greene C, Kealy J, Humphries MM, Gong Y, Hou J, Hudson N, Cassidy LM, Martiniano R, Shashi V, Hooper SR, Grant GA, Kenna PF, Norris K, Callaghan CK, Islam MD, O'Mara SM, Najda Z, Campbell SG, Pachter JS, Thomas J, Williams NM, Humphries P, Murphy KC, Campbell M.

Mol Psychiatry. 2017 Oct 10. doi: 10.1038/mp.2017.156. [Epub ahead of print]

PMID:
28993710
7.

Fitness consequences of peak reproductive effort in a resource pulse system.

Hämäläinen A, McAdam AG, Dantzer B, Lane JE, Haines JA, Humphries MM, Boutin S.

Sci Rep. 2017 Aug 24;7(1):9335. doi: 10.1038/s41598-017-09724-x.

8.

Multilevel and sex-specific selection on competitive traits in North American red squirrels.

Fisher DN, Boutin S, Dantzer B, Humphries MM, Lane JE, McAdam AG.

Evolution. 2017 Jul;71(7):1841-1854. doi: 10.1111/evo.13270. Epub 2017 Jun 8.

PMID:
28543051
9.

Embracing heterothermic diversity: non-stationary waveform analysis of temperature variation in endotherms.

Levesque DL, Menzies AK, Landry-Cuerrier M, Larocque G, Humphries MM.

J Comp Physiol B. 2017 Jul;187(5-6):749-757. doi: 10.1007/s00360-017-1074-9. Epub 2017 Mar 28.

PMID:
28353177
10.

Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.

O'Callaghan J, Crosbie DE, Cassidy PS, Sherwood JM, Flügel-Koch C, Lütjen-Drecoll E, Humphries MM, Reina-Torres E, Wallace D, Kiang AS, Campbell M, Stamer WD, Overby DR, O'Brien C, Tam LCS, Humphries P.

Hum Mol Genet. 2017 Apr 1;26(7):1230-1246. doi: 10.1093/hmg/ddx028.

11.

Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia.

Tam LC, Reina-Torres E, Sherwood JM, Cassidy PS, Crosbie DE, Lütjen-Drecoll E, Flügel-Koch C, Perkumas K, Humphries MM, Kiang AS, O'Callaghan J, Callanan JJ, Read AT, Ethier CR, O'Brien C, Lawrence M, Campbell M, Stamer WD, Overby DR, Humphries P.

Sci Rep. 2017 Jan 16;7:40717. doi: 10.1038/srep40717.

12.

The role of digital data entry in participatory environmental monitoring.

Brammer JR, Brunet ND, Burton AC, Cuerrier A, Danielsen F, Dewan K, Herrmann TM, Jackson MV, Kennett R, Larocque G, Mulrennan M, Pratihast AK, Saint-Arnaud M, Scott C, Humphries MM.

Conserv Biol. 2016 Dec;30(6):1277-1287. doi: 10.1111/cobi.12727. Epub 2016 Sep 15. Review.

PMID:
27032080
13.

Blood-Brain Barrier Dysfunction as a Hallmark Pathology in Chronic Traumatic Encephalopathy.

Doherty CP, O'Keefe E, Wallace E, Loftus T, Keaney J, Kealy J, Humphries MM, Molloy MG, Meaney JF, Farrell M, Campbell M.

J Neuropathol Exp Neurol. 2016 Jul;75(7):656-62. doi: 10.1093/jnen/nlw036. Epub 2016 May 31.

14.

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier.

Keaney J, Walsh DM, O'Malley T, Hudson N, Crosbie DE, Loftus T, Sheehan F, McDaid J, Humphries MM, Callanan JJ, Brett FM, Farrell MA, Humphries P, Campbell M.

Sci Adv. 2015 Sep 4;1(8):e1500472.

15.

Post-weaning parental care increases fitness but is not heritable in North American red squirrels.

Lane JE, McAdam AG, Charmantier A, Humphries MM, Coltman DW, Fletcher Q, Gorrell JC, Boutin S.

J Evol Biol. 2015 Jun;28(6):1203-12. doi: 10.1111/jeb.12633. Epub 2015 May 25.

16.

The nature of nurture in a wild mammal's fitness.

McFarlane SE, Gorrell JC, Coltman DW, Humphries MM, Boutin S, McAdam AG.

Proc Biol Sci. 2015 May 7;282(1806):20142422. doi: 10.1098/rspb.2014.2422.

17.

Selection on female behaviour fluctuates with offspring environment.

Taylor RW, Boutin S, Humphries MM, McAdam AG.

J Evol Biol. 2014 Nov;27(11):2308-21. doi: 10.1111/jeb.12495. Epub 2014 Oct 8.

18.

Predators, energetics and fitness drive neonatal reproductive failure in red squirrels.

Studd EK, Boutin S, McAdam AG, Krebs CJ, Humphries MM.

J Anim Ecol. 2015 Jan;84(1):249-59. doi: 10.1111/1365-2656.12279. Epub 2014 Sep 9.

PMID:
25132293
19.

Very low levels of direct additive genetic variance in fitness and fitness components in a red squirrel population.

McFarlane SE, Gorrell JC, Coltman DW, Humphries MM, Boutin S, McAdam AG.

Ecol Evol. 2014 May;4(10):1729-38. doi: 10.1002/ece3.982. Epub 2014 Apr 11.

20.

Activation of Bax in three models of retinitis pigmentosa.

Comitato A, Sanges D, Rossi A, Humphries MM, Marigo V.

Invest Ophthalmol Vis Sci. 2014 May 13;55(6):3555-62. doi: 10.1167/iovs.14-13917.

PMID:
24825107
21.

IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration.

Doyle SL, Ozaki E, Brennan K, Humphries MM, Mulfaul K, Keaney J, Kenna PF, Maminishkis A, Kiang AS, Saunders SP, Hams E, Lavelle EC, Gardiner C, Fallon PG, Adamson P, Humphries P, Campbell M.

Sci Transl Med. 2014 Apr 2;6(230):230ra44. doi: 10.1126/scitranslmed.3007616.

22.

Antioxidant therapy for retinal disease.

Kiang AS, Humphries MM, Campbell M, Humphries P.

Adv Exp Med Biol. 2014;801:783-9. doi: 10.1007/978-1-4614-3209-8_98. Review.

PMID:
24664771
23.

Current therapeutic strategies for P23H RHO-linked RP.

Nguyen AT, Campbell M, Kiang AS, Humphries MM, Humphries P.

Adv Exp Med Biol. 2014;801:471-6. doi: 10.1007/978-1-4614-3209-8_60. Review.

PMID:
24664733
24.

An overview of the involvement of interleukin-18 in degenerative retinopathies.

Campbell M, Doyle SL, Ozaki E, Kenna PF, Kiang AS, Humphries MM, Humphries P.

Adv Exp Med Biol. 2014;801:409-15. doi: 10.1007/978-1-4614-3209-8_52. Review.

PMID:
24664725
25.

Application of next-generation sequencing to identify genes and mutations causing autosomal dominant retinitis pigmentosa (adRP).

Daiger SP, Bowne SJ, Sullivan LS, Blanton SH, Weinstock GM, Koboldt DC, Fulton RS, Larsen D, Humphries P, Humphries MM, Pierce EA, Chen R, Li Y.

Adv Exp Med Biol. 2014;801:123-9. doi: 10.1007/978-1-4614-3209-8_16.

26.

Reproductive phenology of a food-hoarding mast-seed consumer: resource- and density-dependent benefits of early breeding in red squirrels.

Williams CT, Lane JE, Humphries MM, McAdam AG, Boutin S.

Oecologia. 2014 Mar;174(3):777-88. doi: 10.1007/s00442-013-2826-1. Epub 2013 Nov 16.

PMID:
24241530
27.

City-scale expansion of human thermoregulatory costs.

Hill RW, Muhich TE, Humphries MM.

PLoS One. 2013 Oct 15;8(10):e76238. doi: 10.1371/journal.pone.0076238. eCollection 2013.

28.

Metabolic ecology.

Humphries MM, McCann KS.

J Anim Ecol. 2014 Jan;83(1):7-19. doi: 10.1111/1365-2656.12124. Epub 2013 Sep 12.

PMID:
24028511
29.

Reproductive timing and reliance on hoarded capital resources by lactating red squirrels.

Fletcher QE, Landry-Cuerrier M, Boutin S, McAdam AG, Speakman JR, Humphries MM.

Oecologia. 2013 Dec;173(4):1203-15. doi: 10.1007/s00442-013-2699-3. Epub 2013 Jul 3.

PMID:
23820780
30.

Oxidative damage increases with reproductive energy expenditure and is reduced by food-supplementation.

Fletcher QE, Selman C, Boutin S, McAdam AG, Woods SB, Seo AY, Leeuwenburgh C, Speakman JR, Humphries MM.

Evolution. 2013 May;67(5):1527-36. doi: 10.1111/evo.12014. Epub 2012 Dec 20.

31.

Density triggers maternal hormones that increase adaptive offspring growth in a wild mammal.

Dantzer B, Newman AE, Boonstra R, Palme R, Boutin S, Humphries MM, McAdam AG.

Science. 2013 Jun 7;340(6137):1215-7. doi: 10.1126/science.1235765. Epub 2013 Apr 18.

32.

Disruptive viability selection on adult exploratory behaviour in eastern chipmunks.

Bergeron P, Montiglio PO, Réale D, Humphries MM, Gimenez O, Garant D.

J Evol Biol. 2013 Apr;26(4):766-74. doi: 10.1111/jeb.12081. Epub 2013 Feb 25.

33.

Behavioural impacts of torpor expression: a transient effect in captive eastern chipmunks (Tamias striatus).

Thompson AB, Montiglio PO, Humphries MM.

Physiol Behav. 2013 Feb 17;110-111:115-21. doi: 10.1016/j.physbeh.2013.01.005. Epub 2013 Jan 11.

PMID:
23313403
34.

Barrier modulation in drug delivery to the retina.

Campbell M, Humphries MM, Humphries P.

Methods Mol Biol. 2013;935:371-80. doi: 10.1007/978-1-62703-080-9_26.

PMID:
23150382
35.

Demographic amplification of climate change experienced by the contiguous United States population during the 20(th) century.

Samson J, Berteaux D, McGill BJ, Humphries MM.

PLoS One. 2012;7(10):e45683. doi: 10.1371/journal.pone.0045683. Epub 2012 Oct 24.

36.

Context-dependent correlation between resting metabolic rate and daily energy expenditure in wild chipmunks.

Careau V, Réale D, Garant D, Pelletier F, Speakman JR, Humphries MM.

J Exp Biol. 2013 Feb 1;216(Pt 3):418-26. doi: 10.1242/jeb.076794. Epub 2012 Oct 17.

37.

The energetic and survival costs of growth in free-ranging chipmunks.

Careau V, Bergeron P, Garant D, Réale D, Speakman JR, Humphries MM.

Oecologia. 2013 Jan;171(1):11-23. doi: 10.1007/s00442-012-2385-x. Epub 2012 Jun 13.

PMID:
22692385
38.

Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury.

Campbell M, Hanrahan F, Gobbo OL, Kelly ME, Kiang AS, Humphries MM, Nguyen AT, Ozaki E, Keaney J, Blau CW, Kerskens CM, Cahalan SD, Callanan JJ, Wallace E, Grant GA, Doherty CP, Humphries P.

Nat Commun. 2012 May 22;3:849. doi: 10.1038/ncomms1852.

PMID:
22617289
39.

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.

Doyle SL, Campbell M, Ozaki E, Salomon RG, Mori A, Kenna PF, Farrar GJ, Kiang AS, Humphries MM, Lavelle EC, O'Neill LA, Hollyfield JG, Humphries P.

Nat Med. 2012 May;18(5):791-8. doi: 10.1038/nm.2717.

40.

Within-season synchrony of a masting conifer enhances seed escape.

Archibald DW, McAdam AG, Boutin S, Fletcher QE, Humphries MM.

Am Nat. 2012 Apr;179(4):536-44. doi: 10.1086/664623. Epub 2012 Mar 1.

PMID:
22437182
41.

Low heritabilities, but genetic and maternal correlations between red squirrel behaviours.

Taylor RW, Boon AK, Dantzer B, Réale D, Humphries MM, Boutin S, Gorrell JC, Coltman DW, McAdam AG.

J Evol Biol. 2012 Apr;25(4):614-24. doi: 10.1111/j.1420-9101.2012.02456.x. Epub 2012 Jan 23.

42.

Protein misfolding and potential therapeutic treatments in inherited retinopathies.

Tam LC, Kiang AS, Campbell M, Keaney J, Farrar GJ, Humphries MM, Kenna PF, Humphries P.

Adv Exp Med Biol. 2012;723:567-72. doi: 10.1007/978-1-4614-0631-0_72. Review. No abstract available.

PMID:
22183379
43.

Calpain and photoreceptor apoptosis.

Nguyen AT, Campbell M, Kenna PF, Kiang AS, Tam L, Humphries MM, Humphries P.

Adv Exp Med Biol. 2012;723:547-52. doi: 10.1007/978-1-4614-0631-0_69. Review. No abstract available.

PMID:
22183376
44.

On further development of barrier modulation as a technique for systemic ocular drug delivery.

Hanrahan F, Campbell M, Nguyen AT, Suzuki M, Kiang AS, Tam LC, Gobbo OL, Dhubhghaill SN, Humphries MM, Kenna PF, Humphries P.

Adv Exp Med Biol. 2012;723:155-9. doi: 10.1007/978-1-4614-0631-0_21. Review. No abstract available.

PMID:
22183328
45.

Anticipation and tracking of pulsed resources drive population dynamics in eastern chipmunks.

Bergeron P, Réale D, Humphries MM, Garant D.

Ecology. 2011 Nov;92(11):2027-34.

PMID:
22164826
46.

Stress-induced rise in body temperature is repeatable in free-ranging Eastern chipmunks (Tamias striatus).

Careau V, Réale D, Garant D, Speakman JR, Humphries MM.

J Comp Physiol B. 2012 Apr;182(3):403-14. doi: 10.1007/s00360-011-0628-5. Epub 2011 Nov 11.

PMID:
22076533
47.

C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa.

Humphries MM, Kenna PF, Campbell M, Tam LC, Nguyen AT, Farrar GJ, Botto M, Kiang AS, Humphries P.

Eur J Hum Genet. 2012 Jan;20(1):64-8. doi: 10.1038/ejhg.2011.151. Epub 2011 Aug 24.

48.

Introduction to the symposium: environment, energetics, and fitness: a symposium honoring Donald W. Thomas.

Wojciechowski MS, Humphries MM, Careau V, Pinshow B.

Integr Comp Biol. 2011 Sep;51(3):333-6. doi: 10.1093/icb/icr057. Epub 2011 Jun 22. No abstract available.

PMID:
21700570
49.

Heat for nothing or activity for free? Evidence and implications of activity-thermoregulatory heat substitution.

Humphries MM, Careau V.

Integr Comp Biol. 2011 Sep;51(3):419-31. doi: 10.1093/icb/icr059. Epub 2011 Jun 22. Review.

PMID:
21700569
50.

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement.

Bowne SJ, Humphries MM, Sullivan LS, Kenna PF, Tam LC, Kiang AS, Campbell M, Weinstock GM, Koboldt DC, Ding L, Fulton RS, Sodergren EJ, Allman D, Millington-Ward S, Palfi A, McKee A, Blanton SH, Slifer S, Konidari I, Farrar GJ, Daiger SP, Humphries P.

Eur J Hum Genet. 2011 Oct;19(10):1074-81. doi: 10.1038/ejhg.2011.86. Epub 2011 Jun 8. Erratum in: Eur J Hum Genet. 2011 Oct;19(10):1109.

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