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Items: 50


An ensemble code in medial prefrontal cortex links prior events to outcomes during learning.

Maggi S, Peyrache A, Humphries MD.

Nat Commun. 2018 Jun 7;9(1):2204. doi: 10.1038/s41467-018-04638-2.


Insights into Parkinson's disease from computational models of the basal ganglia.

Humphries MD, Obeso JA, Dreyer JK.

J Neurol Neurosurg Psychiatry. 2018 Apr 17. pii: jnnp-2017-315922. doi: 10.1136/jnnp-2017-315922. [Epub ahead of print] Review.


A probabilistic, distributed, recursive mechanism for decision-making in the brain.

Caballero JA, Humphries MD, Gurney KN.

PLoS Comput Biol. 2018 Apr 3;14(4):e1006033. doi: 10.1371/journal.pcbi.1006033. eCollection 2018 Apr.


A spiral attractor network drives rhythmic locomotion.

Bruno AM, Frost WN, Humphries MD.

Elife. 2017 Aug 7;6. pii: e27342. doi: 10.7554/eLife.27342.


Creating a Registry for Patients with Thoracic Outlet Syndrome.

Humphries MD.

Diagnostics (Basel). 2017 Jun 17;7(2). pii: E36. doi: 10.3390/diagnostics7020036.


Two lives, one REBOA: Hemorrhage control for urgent cesarean hysterectomy in a Jehovah's Witness with placenta percreta.

Russo RM, Girda E, Kennedy V, Humphries MD.

J Trauma Acute Care Surg. 2017 Sep;83(3):551-553. doi: 10.1097/TA.0000000000001602. No abstract available.


Dedicated Research Time During Surgery Residency Leads to a Significant Decline In Self-Assessed Clinical Aptitude and Surgical Skills.

Grova MM, Yang AD, Humphries MD, Galante JM, Salcedo ES.

J Surg Educ. 2017 Nov - Dec;74(6):980-985. doi: 10.1016/j.jsurg.2017.05.009. Epub 2017 May 19.


Medical therapy and intervention do not improve uncomplicated isolated mesenteric artery dissection outcomes over observation alone.

Loeffler JW, Obara H, Fujimura N, Bove P, Newton DH, Zettervall SL, van Petersen AS, Geelkerken RH, Charlton-Ouw KM, Shalhub S, Singh N, Roussel A, Glebova NO, Harlander-Locke MP, Gasper WJ, Humphries MD, Lawrence PF.

J Vasc Surg. 2017 Jul;66(1):202-208. doi: 10.1016/j.jvs.2017.01.059. Epub 2017 May 12.


Non-compressible ABIs are associated with an increased risk of major amputation and major adverse cardiovascular events in patients with critical limb ischemia.

Singh GD, Armstrong EJ, Waldo SW, Alvandi B, Brinza E, Hildebrand J, Amsterdam EA, Humphries MD, Laird JR.

Vasc Med. 2017 Jun;22(3):210-217. doi: 10.1177/1358863X16689831. Epub 2017 Mar 20.


The Goldilocks zone in neural circuits.

Humphries MD.

Elife. 2016 Dec 2;5. pii: e22735. doi: 10.7554/eLife.22735.


Patency of the Internal Iliac Artery after Placement of Common and External Iliac Artery Stents.

Vinogradova M, Lee HJ, Armstrong EJ, Laird J, Humphries MD.

Ann Vasc Surg. 2017 Jan;38:184-189. doi: 10.1016/j.avsg.2016.10.008. Epub 2016 Oct 26.


Amputation trends for patients with lower extremity ulcers due to diabetes and peripheral artery disease using statewide data.

Humphries MD, Brunson A, Li CS, Melnikow J, Romano PS.

J Vasc Surg. 2016 Dec;64(6):1747-1755.e3. doi: 10.1016/j.jvs.2016.06.096. Epub 2016 Sep 23.


Elective Endovascular Aortic Aneurysm Repair Continues to Cost More than Open Abdominal Aortic Aneurysm Repair.

Humphries MD, Suckow BD, Binks JT, McAdam-Marx C, Kraiss LW.

Ann Vasc Surg. 2017 Feb;39:111-118. doi: 10.1016/j.avsg.2016.05.091. Epub 2016 Aug 10.


Therapeutic Anticoagulation for Isolated Calf Deep Vein Thrombosis.

Utter GH, Dhillon TS, Salcedo ES, Shouldice DJ, Reynolds CL, Humphries MD, White RH.

JAMA Surg. 2016 Sep 21;151(9):e161770. doi: 10.1001/jamasurg.2016.1770. Epub 2016 Sep 21.


Covered vs Bare Stents in Lower Limb PAD: We Know the Efficacy, so Let's Determine the Effectiveness and Patient-Centered Outcomes.

Humphries MD.

J Endovasc Ther. 2016 Jun;23(3):453. doi: 10.1177/1526602816646368. No abstract available.


Monitoring Spiking Activity of Many Individual Neurons in Invertebrate Ganglia.

Frost WN, Brandon CJ, Bruno AM, Humphries MD, Moore-Kochlacs C, Sejnowski TJ, Wang J, Hill ES.

Adv Exp Med Biol. 2015;859:127-45. doi: 10.1007/978-3-319-17641-3_5. Review.


Amputation Risk in Patients with Diabetes Mellitus and Peripheral Artery Disease Using Statewide Data.

Humphries MD, Brunson A, Hedayati N, Romano P, Melnkow J.

Ann Vasc Surg. 2016 Jan;30:123-31. doi: 10.1016/j.avsg.2015.04.089. Epub 2015 Jul 11.


Modular deconstruction reveals the dynamical and physical building blocks of a locomotion motor program.

Bruno AM, Frost WN, Humphries MD.

Neuron. 2015 Apr 8;86(1):304-18. doi: 10.1016/j.neuron.2015.03.005. Epub 2015 Mar 26.


Finding communities in sparse networks.

Singh A, Humphries MD.

Sci Rep. 2015 Mar 6;5:8828. doi: 10.1038/srep08828.


A new framework for cortico-striatal plasticity: behavioural theory meets in vitro data at the reinforcement-action interface.

Gurney KN, Humphries MD, Redgrave P.

PLoS Biol. 2015 Jan 6;13(1):e1002034. doi: 10.1371/journal.pbio.1002034. eCollection 2015 Jan. Erratum in: PLoS Biol. 2015 Mar;13(3):e1002099.


Technical and early outcomes using ultrasound-guided reentry for chronic total occlusions.

Baker AC, Humphries MD, Noll RE Jr, Salhan N, Armstrong EJ, Williams TK, Clouse WD.

Ann Vasc Surg. 2015 Jan;29(1):55-62. doi: 10.1016/j.avsg.2014.10.011. Epub 2014 Oct 31.


Reply: To PMID 24725909.

Humphries MD, Laird J, Paz J, Pevec W, Armstrong E.

J Vasc Surg. 2014 Oct;60(4):1120-1. doi: 10.1016/j.jvs.2014.06.005. No abstract available.


Early hypersynchrony in juvenile PINK1(-)/(-) motor cortex is rescued by antidromic stimulation.

Carron R, Filipchuk A, Nardou R, Singh A, Michel FJ, Humphries MD, Hammond C.

Front Syst Neurosci. 2014 May 21;8:95. doi: 10.3389/fnsys.2014.00095. eCollection 2014.


Outcomes of covered versus bare-metal balloon-expandable stents for aortoiliac occlusive disease.

Humphries MD, Armstrong E, Laird J, Paz J, Pevec W.

J Vasc Surg. 2014 Aug;60(2):337-43. doi: 10.1016/j.jvs.2014.02.055. Epub 2014 Apr 13.


Slaves to the rhythm: coupling of the subthalamic nucleus-globus pallidus network in Parkinsonian oscillations.

Humphries MD.

J Physiol. 2014 Apr 1;592(7):1427-8. doi: 10.1113/jphysiol.2014.270736. No abstract available.


Transient and steady-state selection in the striatal microcircuit.

Tomkins A, Vasilaki E, Beste C, Gurney K, Humphries MD.

Front Comput Neurosci. 2014 Jan 20;7:192. doi: 10.3389/fncom.2013.00192. eCollection 2013.


The current management of isolated degenerative femoral artery aneurysms is too aggressive for their natural history.

Lawrence PF, Harlander-Locke MP, Oderich GS, Humphries MD, Landry GJ, Ballard JL, Abularrage CJ; Vascular Low-Frequency Disease Consortium.

J Vasc Surg. 2014 Feb;59(2):343-9. doi: 10.1016/j.jvs.2013.08.090.


Gender and outcomes of carotid artery interventions.

Hedayati N, Humphries MD, Zhou W.

Vasc Endovascular Surg. 2014 Feb;48(2):99-105. doi: 10.1177/1538574413510978. Epub 2013 Dec 16. Review.


Integrating cortico-limbic-basal ganglia architectures for learning model-based and model-free navigation strategies.

Khamassi M, Humphries MD.

Front Behav Neurosci. 2012 Nov 27;6:79. doi: 10.3389/fnbeh.2012.00079. eCollection 2012.


Population-wide distributions of neural activity during perceptual decision-making.

Wohrer A, Humphries MD, Machens CK.

Prog Neurobiol. 2013 Apr;103:156-93. doi: 10.1016/j.pneurobio.2012.09.004. Epub 2012 Nov 1. Review.


Network effects of subthalamic deep brain stimulation drive a unique mixture of responses in basal ganglia output.

Humphries MD, Gurney K.

Eur J Neurosci. 2012 Jul;36(2):2240-51. doi: 10.1111/j.1460-9568.2012.08085.x.


Dopaminergic Control of the Exploration-Exploitation Trade-Off via the Basal Ganglia.

Humphries MD, Khamassi M, Gurney K.

Front Neurosci. 2012 Feb 6;6:9. doi: 10.3389/fnins.2012.00009. eCollection 2012.


Onset of Pup Locomotion Coincides with Loss of NR2C/D-Mediated Cortico-Striatal EPSCs and Dampening of Striatal Network Immature Activity.

Dehorter N, Michel FJ, Marissal T, Rotrou Y, Matrot B, Lopez C, Humphries MD, Hammond C.

Front Cell Neurosci. 2011 Nov 21;5:24. doi: 10.3389/fncel.2011.00024. eCollection 2011.


Spike-train communities: finding groups of similar spike trains.

Humphries MD.

J Neurosci. 2011 Feb 9;31(6):2321-36. doi: 10.1523/JNEUROSCI.2853-10.2011.


Reconstructing the three-dimensional GABAergic microcircuit of the striatum.

Humphries MD, Wood R, Gurney K.

PLoS Comput Biol. 2010 Nov 24;6(11):e1001011. doi: 10.1371/journal.pcbi.1001011.


Early duplex scanning after infrainguinal endovascular therapy.

Humphries MD, Pevec WC, Laird JR, Yeo KK, Hedayati N, Dawson DL.

J Vasc Surg. 2011 Feb;53(2):353-8. doi: 10.1016/j.jvs.2010.08.045. Epub 2010 Oct 25.


Asymptomatic bilateral external iliac vein aneurysms in a young athlete: case report and literature review.

Humphries MD, Dawson DL.

Vasc Endovascular Surg. 2010 Oct;44(7):594-6. doi: 10.1177/1538574410366488. Epub 2010 Jun 2. Review.


Capturing dopaminergic modulation and bimodal membrane behaviour of striatal medium spiny neurons in accurate, reduced models.

Humphries MD, Lepora N, Wood R, Gurney K.

Front Comput Neurosci. 2009 Nov 26;3:26. doi: 10.3389/neuro.10.026.2009. eCollection 2009.


The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward.

Humphries MD, Prescott TJ.

Prog Neurobiol. 2010 Apr;90(4):385-417. doi: 10.1016/j.pneurobio.2009.11.003. Epub 2009 Nov 24. Review.


Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit.

Humphries MD, Wood R, Gurney K.

Neural Netw. 2009 Oct;22(8):1174-88. doi: 10.1016/j.neunet.2009.07.018. Epub 2009 Jul 19. Review.


Network 'small-world-ness': a quantitative method for determining canonical network equivalence.

Humphries MD, Gurney K.

PLoS One. 2008 Apr 30;3(4):e0002051. doi: 10.1371/journal.pone.0002051.


Solution methods for a new class of simple model neurons.

Humphries MD, Gurney K.

Neural Comput. 2007 Dec;19(12):3216-25.


Is there a brainstem substrate for action selection?

Humphries MD, Gurney K, Prescott TJ.

Philos Trans R Soc Lond B Biol Sci. 2007 Sep 29;362(1485):1627-39.


A physiologically plausible model of action selection and oscillatory activity in the basal ganglia.

Humphries MD, Stewart RD, Gurney KN.

J Neurosci. 2006 Dec 13;26(50):12921-42.


The brainstem reticular formation is a small-world, not scale-free, network.

Humphries MD, Gurney K, Prescott TJ.

Proc Biol Sci. 2006 Feb 22;273(1585):503-11.


A robot model of the basal ganglia: behavior and intrinsic processing.

Prescott TJ, Montes González FM, Gurney K, Humphries MD, Redgrave P.

Neural Netw. 2006 Jan;19(1):31-61. Epub 2005 Sep 8.


The DNA sequence and analysis of human chromosome 6.

Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S.

Nature. 2003 Oct 23;425(6960):805-11.


The role of intra-thalamic and thalamocortical circuits in action selection.

Humphries MD, Gurney KN.

Network. 2002 Feb;13(1):131-56.


A pulsed neural network model of bursting in the basal ganglia.

Humphries MD, Gurney KN.

Neural Netw. 2001 Jul-Sep;14(6-7):845-63.


Amygdaloid-lesion hyperphagia: impaired response to caloric challenges and altered macronutrient selection.

King BM, Rossiter KN, Stines SG, Zaharan GM, Cook JT, Humphries MD, York DA.

Am J Physiol. 1998 Aug;275(2 Pt 2):R485-93.


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