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Sex Differences in Complications and Outcomes of Cardiac Implantable Electronic Devices: Time to Evaluate Our Practice.

Humphries KH, Hawkins N.

Can J Cardiol. 2020 Jan;36(1):16-18. doi: 10.1016/j.cjca.2019.09.009. Epub 2019 Sep 24. No abstract available.


Individualizing Revascularization Strategy for Diabetic Patients With Multivessel Coronary Disease.

Qintar M, Humphries KH, Park JE, Arnold SV, Tang Y, Jones P, Salisbury AC, Kureshi F, Farkouh ME, Fuster V, Cohen DJ, Spertus JA.

J Am Coll Cardiol. 2019 Oct 22;74(16):2074-2084. doi: 10.1016/j.jacc.2019.07.083.


Empirical Insights When Defining the Population Burden of Atrial Fibrillation and Oral Anticoagulation Utilization Using Administrative Data.

Hawkins NM, Daniele PR, Humphries KH, Ezekowitz JA, McAlister FA, Sandhu RK, Kaul P.

Can J Cardiol. 2019 Oct;35(10):1412-1415. doi: 10.1016/j.cjca.2019.05.009. Epub 2019 May 15.


Premature Atherosclerotic Cardiovascular Disease: Trends in Incidence, Risk Factors, and Sex-Related Differences, 2000 to 2016.

Vikulova DN, Grubisic M, Zhao Y, Lynch K, Humphries KH, Pimstone SN, Brunham LR.

J Am Heart Assoc. 2019 Jul 16;8(14):e012178. doi: 10.1161/JAHA.119.012178. Epub 2019 Jul 8.


Impact of Local Anesthesia Only Versus Procedural Sedation Using the Vancouver Clinical Pathway for TAVR: Insights From the 3M TAVR Study.

Sathananthan J, Webb JG, Lauck SB, Cairns J, Humphries KH, Nazif T, Thourani VH, Cohen DJ, Leon MB, Wood DA; 3M TAVR Study Investigators.

JACC Cardiovasc Interv. 2019 May 27;12(10):1000-1001. doi: 10.1016/j.jcin.2019.02.014. No abstract available.


C-Reactive Protein Levels and the Risk of Incident Cardiovascular and Cerebrovascular Events in Patients with Obstructive Sleep Apnea.

Ayas NT, Hirsch Allen AJ, Fox N, Peres B, Mehrtash M, Humphries KH, Jen R, Taylor CM, van Eeden SF.

Lung. 2019 Aug;197(4):459-464. doi: 10.1007/s00408-019-00237-0. Epub 2019 May 14.


Coronary atheroma regression and adverse cardiac events: A systematic review and meta-regression analysis.

Bhindi R, Guan M, Zhao Y, Humphries KH, Mancini GBJ.

Atherosclerosis. 2019 May;284:194-201. doi: 10.1016/j.atherosclerosis.2019.03.005. Epub 2019 Mar 11. Review.


The Vancouver 3M (Multidisciplinary, Multimodality, But Minimalist) Clinical Pathway Facilitates Safe Next-Day Discharge Home at Low-, Medium-, and High-Volume Transfemoral Transcatheter Aortic Valve Replacement Centers: The 3M TAVR Study.

Wood DA, Lauck SB, Cairns JA, Humphries KH, Cook R, Welsh R, Leipsic J, Genereux P, Moss R, Jue J, Blanke P, Cheung A, Ye J, Dvir D, Umedaly H, Klein R, Rondi K, Poulter R, Stub D, Barbanti M, Fahmy P, Htun N, Murdoch D, Prakash R, Barker M, Nickel K, Thakkar J, Sathananthan J, Tyrell B, Al-Qoofi F, Velianou JL, Natarajan MK, Wijeysundera HC, Radhakrishnan S, Horlick E, Osten M, Buller C, Peterson M, Asgar A, Palisaitis D, Masson JB, Kodali S, Nazif T, Thourani V, Babaliaros VC, Cohen DJ, Park JE, Leon MB, Webb JG.

JACC Cardiovasc Interv. 2019 Mar 11;12(5):459-469. doi: 10.1016/j.jcin.2018.12.020.


The Effect of Canola Oil on Body Weight and Composition: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials.

Raeisi-Dehkordi H, Amiri M, Humphries KH, Salehi-Abargouei A.

Adv Nutr. 2019 May 1;10(3):419-432. doi: 10.1093/advances/nmy108.


Racism Is Not a Factor in Door-to-electrocardiogram Times of Patients With Symptoms of Acute Coronary Syndrome: A Prospective, Observational Study.

Mackay MH, Ratner PA, Veenstra G, Scheuermeyer FX, Grubisic M, Ramanathan K, Murray C, Humphries KH.

Acad Emerg Med. 2019 May;26(5):491-500. doi: 10.1111/acem.13569. Epub 2018 Oct 21.


Sex Differences in Cardiac Troponin Testing in Patients Presenting to the Emergency Department with Chest Pain.

Humphries KH, Gao M, Lee MK, Izadnegahdar M, Holmes DT, Scheuermeyer FX, Mackay M, Mattman A, Grafstein E.

J Womens Health (Larchmt). 2018 Nov;27(11):1327-1334. doi: 10.1089/jwh.2017.6812. Epub 2018 Jul 16.


Ranolazine for Symptomatic Management of Microvascular Angina.

Rayner-Hartley E, Parvand M, Humphries KH, Starovoytov A, Park JE, Sedlak T.

Am J Ther. 2018 May 9. doi: 10.1097/MJT.0000000000000779. [Epub ahead of print]


Determinants of long-term clinical outcomes in patients with angina but without obstructive coronary artery disease: a systematic review and meta-analysis.

Radico F, Zimarino M, Fulgenzi F, Ricci F, Di Nicola M, Jespersen L, Chang SM, Humphries KH, Marzilli M, De Caterina R.

Eur Heart J. 2018 Jun 14;39(23):2135-2146. doi: 10.1093/eurheartj/ehy185.


The design and rationale of SAVE BC: The Study to Avoid CardioVascular Events in British Columbia.

Brunham LR, Lynch K, English A, Sutherland R, Weng J, Cho R, Wong GC, Anis AH, Francis GA, Khan NA, McManus B, Wood D, Walley KR, Leipsic J, Humphries KH, Hoens A, Krahn AD, John Mancini GB, Pimstone S.

Clin Cardiol. 2018 Jul;41(7):888-895. doi: 10.1002/clc.22959. Epub 2018 Jun 11.


Effect of Lowering Diastolic Pressure in Patients With and Without Cardiovascular Disease: Analysis of the SPRINT (Systolic Blood Pressure Intervention Trial).

Khan NA, Rabkin SW, Zhao Y, McAlister FA, Park JE, Guan M, Chan S, Humphries KH.

Hypertension. 2018 May;71(5):840-847. doi: 10.1161/HYPERTENSIONAHA.117.10177. Epub 2018 Mar 26.


Electrolyte minerals intake and cardiovascular health.

Mohammadifard N, Gotay C, Humphries KH, Ignaszewski A, Esmaillzadeh A, Sarrafzadegan N.

Crit Rev Food Sci Nutr. 2019;59(15):2375-2385. doi: 10.1080/10408398.2018.1453474. Epub 2018 Apr 4. Review.


Research in Women's Cardiovascular Health-Progress at Last?

Humphries KH, Pilote L.

Can J Cardiol. 2018 Apr;34(4):349-353. doi: 10.1016/j.cjca.2017.10.019. Epub 2017 Dec 29. No abstract available.


Sex Differences in Diagnoses, Treatment, and Outcomes for Emergency Department Patients With Chest Pain and Elevated Cardiac Troponin.

Humphries KH, Lee MK, Izadnegahdar M, Gao M, Holmes DT, Scheuermeyer FX, Mackay M, Mattman A, Grafstein E.

Acad Emerg Med. 2018 Apr;25(4):413-424. doi: 10.1111/acem.13371. Epub 2018 Feb 8.


Surgical Versus Percutaneous Coronary Revascularization in Patients With Diabetes and Acute Coronary Syndromes.

Ramanathan K, Abel JG, Park JE, Fung A, Mathew V, Taylor CM, Mancini GBJ, Gao M, Ding L, Verma S, Humphries KH, Farkouh ME.

J Am Coll Cardiol. 2017 Dec 19;70(24):2995-3006. doi: 10.1016/j.jacc.2017.10.029.


Trace minerals intake: Risks and benefits for cardiovascular health.

Mohammadifard N, Humphries KH, Gotay C, Mena-Sánchez G, Salas-Salvadó J, Esmaillzadeh A, Ignaszewski A, Sarrafzadegan N.

Crit Rev Food Sci Nutr. 2019;59(8):1334-1346. doi: 10.1080/10408398.2017.1406332. Epub 2017 Dec 13. Review.


Longitudinal changes in visceral and subcutaneous adipose tissue and metabolic syndrome: Results from the Multicultural Community Health Assessment Trial (M-CHAT).

Tu AW, Humphries KH, Lear SA.

Diabetes Metab Syndr. 2017 Dec;11 Suppl 2:S957-S961. doi: 10.1016/j.dsx.2017.07.022. Epub 2017 Jul 8.


Reduction of LDL-C-related residual cardiovascular risk with ezetimibe: are mechanistic considerations warranted in practice?

Humphries KH, Mancini GBJ.

Eur Heart J. 2017 Aug 1;38(29):2276-2278. doi: 10.1093/eurheartj/ehx275. No abstract available.


Sex differences in cardiovascular disease - Impact on care and outcomes.

Humphries KH, Izadnegahdar M, Sedlak T, Saw J, Johnston N, Schenck-Gustafsson K, Shah RU, Regitz-Zagrosek V, Grewal J, Vaccarino V, Wei J, Bairey Merz CN.

Front Neuroendocrinol. 2017 Jul;46:46-70. doi: 10.1016/j.yfrne.2017.04.001. Epub 2017 Apr 18. Review. No abstract available.


Outcomes following percutaneous coronary revascularization among South Asian and Chinese Canadians.

Mackay MH, Singh R, Boone RH, Park JE, Humphries KH.

BMC Cardiovasc Disord. 2017 Apr 19;17(1):101. doi: 10.1186/s12872-017-0535-0.


Cardiac Medication Use in Patients with Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease.

Adatia F, Galway S, Grubisic M, Lee M, Daniele P, Humphries KH, Sedlak TL.

J Womens Health (Larchmt). 2017 Nov;26(11):1185-1192. doi: 10.1089/jwh.2016.5984. Epub 2017 Apr 6.


Sex Differences in Cardiac Medication Use Post-Catheterization in Patients Undergoing Coronary Angiography for Stable Angina with Nonobstructive Coronary Artery Disease.

Galway S, Adatia F, Grubisic M, Lee M, Daniele P, Humphries KH, Sedlak TL.

J Womens Health (Larchmt). 2017 Sep;26(9):976-983. doi: 10.1089/jwh.2016.5983. Epub 2017 Apr 6.


Early non-persistence with dabigatran and rivaroxaban in patients with atrial fibrillation.

Jackevicius CA, Tsadok MA, Essebag V, Atzema C, Eisenberg MJ, Tu JV, Lu L, Rahme E, Ho PM, Turakhia M, Humphries KH, Behlouli H, Zhou L, Pilote L.

Heart. 2017 Sep;103(17):1331-1338. doi: 10.1136/heartjnl-2016-310672. Epub 2017 Mar 12.


Progression of paroxysmal to persistent atrial fibrillation: 10-year follow-up in the Canadian Registry of Atrial Fibrillation.

Padfield GJ, Steinberg C, Swampillai J, Qian H, Connolly SJ, Dorian P, Green MS, Humphries KH, Klein GJ, Sheldon R, Talajic M, Kerr CR.

Heart Rhythm. 2017 Jun;14(6):801-807. doi: 10.1016/j.hrthm.2017.01.038. Epub 2017 Feb 21.


The predictive relationship between baseline insulin and glucose with subclinical carotid atherosclerosis after 5 years in a multi-ethnic cohort.

Fowokan AO, Lesser IA, Humphries KH, Mancini JG, Lear SA.

Atherosclerosis. 2017 Feb;257:146-151. doi: 10.1016/j.atherosclerosis.2016.12.013. Epub 2016 Dec 15.


Cardiac Rehabilitation Adherence: Another Gender-Treatment Paradox.

Sedlak TL, Humphries KH.

Can J Cardiol. 2016 Nov;32(11):1283-1285. doi: 10.1016/j.cjca.2015.12.032. Epub 2016 Apr 27. No abstract available.


A Plaque Disruption Index Identifies Patients with Non-STE-Type 1 Myocardial Infarction within 24 Hours of Troponin Positivity.

Al-Mohaissen MA, Carere RG, Mancini GB, Humphries KH, Whalen BA, Lee T, Scheuermeyer FX, Ignaszewski AP.

PLoS One. 2016 Oct 6;11(10):e0164315. doi: 10.1371/journal.pone.0164315. eCollection 2016.


Ischemic Predictors of Outcomes in Women With Signs and Symptoms of Ischemia and Nonobstructive Coronary Artery Disease.

Sedlak TL, Guan M, Lee M, Humphries KH, Johnson BD, Pepine CJ, Merz CN.

JAMA Cardiol. 2016 Jul 1;1(4):491-2. doi: 10.1001/jamacardio.2016.0740. No abstract available.


Contemporary Review on Spontaneous Coronary Artery Dissection.

Saw J, Mancini GBJ, Humphries KH.

J Am Coll Cardiol. 2016 Jul 19;68(3):297-312. doi: 10.1016/j.jacc.2016.05.034. Review. Erratum in: J Am Coll Cardiol. 2016 Oct 4;68(14):1606.


Sex and Ethnic Differences in Outcomes of Acute Coronary Syndrome and Stable Angina Patients With Obstructive Coronary Artery Disease.

Izadnegahdar M, Mackay M, Lee MK, Sedlak TL, Gao M, Bairey Merz CN, Humphries KH.

Circ Cardiovasc Qual Outcomes. 2016 Feb;9(2 Suppl 1):S26-35. doi: 10.1161/CIRCOUTCOMES.115.002483. Erratum in: Circ Cardiovasc Qual Outcomes. 2016 May;9(3):341.


Sex-Specific Differences at Presentation and Outcomes Among Patients Undergoing Transcatheter Aortic Valve Replacement: A Cohort Study.

Kodali S, Williams MR, Doshi D, Hahn RT, Humphries KH, Nkomo VT, Cohen DJ, Douglas PS, Mack M, Xu K, Svensson L, Thourani VH, Tuzcu EM, Weissman NJ, Leon M, Kirtane AJ.

Ann Intern Med. 2016 Mar 15;164(6):377-84. doi: 10.7326/M15-0121. Epub 2016 Feb 23.


Sex Versus Gender-Related Characteristics: Which Predicts Outcome After Acute Coronary Syndrome in the Young?

Pelletier R, Khan NA, Cox J, Daskalopoulou SS, Eisenberg MJ, Bacon SL, Lavoie KL, Daskupta K, Rabi D, Humphries KH, Norris CM, Thanassoulis G, Behlouli H, Pilote L; GENESIS-PRAXY Investigators.

J Am Coll Cardiol. 2016 Jan 19;67(2):127-135. doi: 10.1016/j.jacc.2015.10.067.


Sex Differences in Dabigatran Use, Safety, And Effectiveness In a Population-Based Cohort of Patients With Atrial Fibrillation.

Avgil Tsadok M, Jackevicius CA, Rahme E, Humphries KH, Pilote L.

Circ Cardiovasc Qual Outcomes. 2015 Nov;8(6):593-9. doi: 10.1161/CIRCOUTCOMES.114.001398. Epub 2015 Oct 27.


Sex Disparities in Post-Acute Myocardial Infarction Pharmacologic Treatment Initiation and Adherence: Problem for Young Women.

Smolina K, Ball L, Humphries KH, Khan N, Morgan SG.

Circ Cardiovasc Qual Outcomes. 2015 Nov;8(6):586-92. doi: 10.1161/CIRCOUTCOMES.115.001987. Epub 2015 Oct 13.


Spontaneous Coronary Artery Dissection Misdiagnosed as Takotsubo Cardiomyopathy: A Case Series.

Chou AY, Sedlak T, Aymong E, Sheth T, Starovoytov A, Humphries KH, Mancini GB, Saw J.

Can J Cardiol. 2015 Aug;31(8):1073.e5-8. doi: 10.1016/j.cjca.2015.03.018. Epub 2015 Mar 17.


A meta-analysis of sex-related differences in outcomes after primary percutaneous intervention for ST-segment elevation myocardial infarction.

Conrotto F, D'Ascenzo F, Humphries KH, Webb JG, Scacciatella P, Grasso C, D'Amico M, Biondi-Zoccai G, Gaita F, Marra S.

J Interv Cardiol. 2015 Apr;28(2):132-40. doi: 10.1111/joic.12195. Review.


Effect of gender after transcatheter aortic valve implantation: a meta-analysis.

Conrotto F, D'Ascenzo F, Presbitero P, Humphries KH, Webb JG, O'Connor SA, Morice MC, Lefèvre T, Grasso C, Sbarra P, Taha S, Omedè P, Grosso Marra W, Salizzoni S, Moretti C, D'Amico M, Biondi-Zoccai G, Gaita F, Marra S.

Ann Thorac Surg. 2015 Mar;99(3):809-16. doi: 10.1016/j.athoracsur.2014.09.089. Epub 2015 Jan 27.


Response to letter regarding article, "Warfarin use and the risk for stroke and bleeding in patients with atrial fibrillation undergoing dialysis".

Shah M, Avgil Tsadok M, Jackevicius CA, Essebag V, Eisenberg MJ, Rahme E, Humphries KH, Tu JV, Behlouli H, Guo H, Pilote L.

Circulation. 2014 Dec 23;130(25):e428-9. doi: 10.1161/CIRCULATIONAHA.114.012785. No abstract available.


Outcomes and transfer patterns for first Non-ST-elevation myocardial infarction (NSTEMI): comparisons between community and tertiary care hospitals.

Sedlak TL, Gao M, Lee M, Humphries KH, Cairns JA.

Can J Cardiol. 2014 Dec;30(12):1562-9. doi: 10.1016/j.cjca.2014.09.008. Epub 2014 Sep 16.


Canadian Institutes of Health Research dissemination grant on high-sensitivity cardiac troponin.

Kavsak PA, Jaffe AS, Hickman PE, Mills NL, Humphries KH, McRae A, Devereaux PJ, Lamy A, Whitlock R, Dhesy-Thind SK, Potter JM, Worster A.

Clin Biochem. 2014 Nov;47(16-17):155-7. doi: 10.1016/j.clinbiochem.2014.10.002. Epub 2014 Oct 7. No abstract available.


Health-related quality of life in premature acute coronary syndrome: does patient sex or gender really matter?

Leung Yinko SS, Pelletier R, Behlouli H, Norris CM, Humphries KH, Pilote L; GENESIS‐PRAXY investigators.

J Am Heart Assoc. 2014 Jul 28;3(4). pii: e000901. doi: 10.1161/JAHA.114.000901.


Incorporating sex and gender in cardiovascular research: the time has come.

Pilote L, Humphries KH.

Can J Cardiol. 2014 Jul;30(7):699-702. doi: 10.1016/j.cjca.2013.09.021. Epub 2014 May 29. Review. No abstract available.


Sex-related differences in access to care among patients with premature acute coronary syndrome.

Pelletier R, Humphries KH, Shimony A, Bacon SL, Lavoie KL, Rabi D, Karp I, Tsadok MA, Pilote L; GENESIS-PRAXY Investigators.

CMAJ. 2014 Apr 15;186(7):497-504. doi: 10.1503/cmaj.131450. Epub 2014 Mar 17.


Prevalence and control of high blood pressure in primary care: results from the German Metabolic and Cardiovascular Risk Study (GEMCAS).

Balijepalli C, Bramlage P, Lösch C, Zemmrich C, Humphries KH, Moebus S.

Hypertens Res. 2014 Jun;37(6):580-4. doi: 10.1038/hr.2014.40. Epub 2014 Mar 13.


Sex-specific factors in microvascular angina.

Sedlak T, Izadnegahdar M, Humphries KH, Bairey Merz CN.

Can J Cardiol. 2014 Jul;30(7):747-755. doi: 10.1016/j.cjca.2013.08.013. Epub 2014 Feb 27. Review.


Sex-related differences in outcomes after transcatheter or surgical aortic valve replacement in patients with severe aortic stenosis: Insights from the PARTNER Trial (Placement of Aortic Transcatheter Valve).

Williams M, Kodali SK, Hahn RT, Humphries KH, Nkomo VT, Cohen DJ, Douglas PS, Mack M, McAndrew TC, Svensson L, Thourani VH, Tuzcu EM, Weissman NJ, Kirtane AJ, Leon MB.

J Am Coll Cardiol. 2014 Apr 22;63(15):1522-8. doi: 10.1016/j.jacc.2014.01.036. Epub 2014 Feb 19.

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