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Items: 1 to 50 of 345

1.

Probody Therapeutics: An Emerging Class of Therapies Designed to Enhance On-target Effects with Reduced Off-tumor Toxicity for Use in Immuno-Oncology.

Autio KA, Boni V, Humphrey RW, Naing A.

Clin Cancer Res. 2019 Oct 10. pii: clincanres.1457.2019. doi: 10.1158/1078-0432.CCR-19-1457. [Epub ahead of print]

PMID:
31601568
2.

Benefits and Risks of High-Intensity Interval Training in Patients With Coronary Artery Disease.

Quindry JC, Franklin BA, Chapman M, Humphrey R, Mathis S.

Am J Cardiol. 2019 Apr 15;123(8):1370-1377. doi: 10.1016/j.amjcard.2019.01.008. Epub 2019 Jan 24. Review.

PMID:
30732854
3.

UX007 for the treatment of long chain-fatty acid oxidation disorders: Safety and efficacy in children and adults following 24weeks of treatment.

Vockley J, Burton B, Berry GT, Longo N, Phillips J, Sanchez-Valle A, Tanpaiboon P, Grunewald S, Murphy E, Humphrey R, Mayhew J, Bowden A, Zhang L, Cataldo J, Marsden DL, Kakkis E.

Mol Genet Metab. 2017 Apr;120(4):370-377. doi: 10.1016/j.ymgme.2017.02.005. Epub 2017 Feb 7.

4.

The Benefits of Merging Leadership Research and Emotions Research.

Humphrey RH, Burch GF, Adams LL.

Front Psychol. 2016 Jul 6;7:1022. doi: 10.3389/fpsyg.2016.01022. eCollection 2016. Review.

5.

Data-driven Casualty Estimation and Disease Nonbattle Injury/Battle Injury Rates in Recent Campaigns.

Wojcik BE, Humphrey RJ, Hosek BJ, Stein CR.

US Army Med Dep J. 2016 Apr-Sep;(2-16):8-14.

PMID:
27215860
6.

CCR 20th Anniversary Commentary: Immune-Related Response Criteria--Capturing Clinical Activity in Immuno-Oncology.

Hoos A, Wolchok JD, Humphrey RW, Hodi FS.

Clin Cancer Res. 2015 Nov 15;21(22):4989-91. doi: 10.1158/1078-0432.CCR-14-3128.

7.

Immunoglobulin A in Bovine Milk: A Potential Functional Food?

Cakebread JA, Humphrey R, Hodgkinson AJ.

J Agric Food Chem. 2015 Aug 26;63(33):7311-6. doi: 10.1021/acs.jafc.5b01836. Epub 2015 Aug 12.

PMID:
26165692
8.

Risk of dental disease non-battle injuries and severity of dental disease in deployed U.S. Army personnel.

Wojcik BE, Szeszel-Fedorowicz W, Humphrey RJ, Colthirst P, Guerrero AC, Simecek JW, Fedorowicz A, Eikenberg S, Rogers GG, DeNicolo P.

Mil Med. 2015 May;180(5):570-7. doi: 10.7205/MILMED-D-14-00364.

PMID:
25939113
9.

Electrical Myostimulation (EMS) Improves Glucose Metabolism and Oxygen Uptake in Type 2 Diabetes Mellitus Patients--Results from the EMS Study.

van Buuren F, Horstkotte D, Mellwig KP, Fründ A, Vlachojannis M, Bogunovic N, Dimitriadis Z, Vortherms J, Humphrey R, Niebauer J.

Diabetes Technol Ther. 2015 Jun;17(6):413-9. doi: 10.1089/dia.2014.0315. Epub 2015 Mar 3.

PMID:
25734937
10.

Spinal injury hospitalizations among U.S. Army soldiers deployed to Iraq and Afghanistan.

Wojcik BE, Curley KC, Szeszel-Fedorowicz W, Stein CR, Humphrey RJ.

Mil Med. 2015 Feb;180(2):216-23. doi: 10.7205/MILMED-D-14-00061.

PMID:
25643390
11.

Clinically led performance management in secondary healthcare: evaluating the attitudes of medical and non-clinical managers.

Trebble TM, Paul M, Hockey PM, Heyworth N, Humphrey R, Powell T, Clarke N.

BMJ Qual Saf. 2015 Mar;24(3):212-20. doi: 10.1136/bmjqs-2014-003219. Epub 2015 Jan 27.

PMID:
25628428
12.

Effectiveness of preoperative physical therapy for elective cardiac surgery.

Humphrey R, Malone D.

Phys Ther. 2015 Feb;95(2):160-6. doi: 10.2522/ptj.20130323. Epub 2014 Oct 24. Review. No abstract available.

PMID:
25343961
13.

Loss of TRB3 alters dynamics of MLK3-JNK signaling and inhibits cytokine-activated pancreatic beta cell death.

Humphrey RK, Ray A, Gonuguntla S, Hao E, Jhala US.

J Biol Chem. 2014 Oct 24;289(43):29994-30004. doi: 10.1074/jbc.M114.575613. Epub 2014 Sep 9.

14.

Transcobalamin derived from bovine milk stimulates apical uptake of vitamin B12 into human intestinal epithelial cells.

Hine B, Boggs I, Green R, Miller JW, Hovey RC, Humphrey R, Wheeler TT.

J Cell Biochem. 2014 Nov;115(11):1948-54. doi: 10.1002/jcb.24866.

PMID:
24913691
15.

An automated minimum retest interval rejection rule reduces repeat CRP workload and expenditure, and influences clinician-requesting behaviour.

Waldron JL, Ford C, Dobie D, Danks G, Humphrey R, Rolli A, Gama R.

J Clin Pathol. 2014 Aug;67(8):731-3. doi: 10.1136/jclinpath-2014-202256. Epub 2014 Jun 4.

PMID:
24898477
16.

The influence of ethnicity and gender on navigating an acute coronary syndrome event.

King-Shier KM, Singh S, LeBlanc P, Mather CM, Humphrey R, Quan H, Khan NA.

Eur J Cardiovasc Nurs. 2015 Jun;14(3):240-7. doi: 10.1177/1474515114529690. Epub 2014 Mar 27.

PMID:
24682918
17.

Evaluation of monoclonal and oligoclonal gammopathies in a pediatric population in a major urban center.

Karafin MS, Humphrey RL, Detrick B.

Am J Clin Pathol. 2014 Apr;141(4):482-7. doi: 10.1309/AJCP2JBDEELPA7HT.

PMID:
24619747
18.

Cardiac rehabilitation in Europe.

Humphrey R, Guazzi M, Niebauer J.

Prog Cardiovasc Dis. 2014 Mar-Apr;56(5):551-6. doi: 10.1016/j.pcad.2013.08.004. Epub 2013 Oct 5. Review.

PMID:
24607021
19.

Insights from major themes at EuroPRevent 2013, Rome, Italy.

Niebauer J, Humphrey R.

Future Cardiol. 2014 Jan;10(1):39-41. doi: 10.2217/fca.13.46. No abstract available.

PMID:
24344661
20.

A queer-theoretical approach to community health psychology.

Easpaig BR, Fryer DM, Linn SE, Humphrey RH.

J Health Psychol. 2014 Jan;19(1):117-25. doi: 10.1177/1359105313500259. Epub 2013 Sep 20.

PMID:
24058123
21.

Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models.

Jure-Kunkel M, Masters G, Girit E, Dito G, Lee F, Hunt JT, Humphrey R.

Cancer Immunol Immunother. 2013 Sep;62(9):1533-45. doi: 10.1007/s00262-013-1451-5. Epub 2013 Jul 20.

22.

Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma.

Wolchok JD, Hodi FS, Weber JS, Allison JP, Urba WJ, Robert C, O'Day SJ, Hoos A, Humphrey R, Berman DM, Lonberg N, Korman AJ.

Ann N Y Acad Sci. 2013 Jul;1291:1-13. doi: 10.1111/nyas.12180. Epub 2013 Jun 17. Review.

23.

Exposure-response relationships of the efficacy and safety of ipilimumab in patients with advanced melanoma.

Feng Y, Roy A, Masson E, Chen TT, Humphrey R, Weber JS.

Clin Cancer Res. 2013 Jul 15;19(14):3977-86. doi: 10.1158/1078-0432.CCR-12-3243. Epub 2013 Jun 5.

24.

Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb.

Lancman JJ, Zvenigorodsky N, Gates KP, Zhang D, Solomon K, Humphrey RK, Kuo T, Setiawan L, Verkade H, Chi YI, Jhala US, Wright CV, Stainier DY, Dong PD.

Development. 2013 Jul;140(13):2669-79. doi: 10.1242/dev.090993. Epub 2013 May 29.

25.

Four-year survival rates for patients with metastatic melanoma who received ipilimumab in phase II clinical trials.

Wolchok JD, Weber JS, Maio M, Neyns B, Harmankaya K, Chin K, Cykowski L, de Pril V, Humphrey R, Lebbé C.

Ann Oncol. 2013 Aug;24(8):2174-80. doi: 10.1093/annonc/mdt161. Epub 2013 May 10.

26.

Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell death.

Humphrey RK, Yu SM, Bellary A, Gonuguntla S, Yebra M, Jhala US.

J Biol Chem. 2013 Jan 25;288(4):2428-40. doi: 10.1074/jbc.M112.425884. Epub 2012 Nov 21.

27.

Increasing referral and participation rates to outpatient cardiac rehabilitation: the valuable role of healthcare professionals in the inpatient and home health settings: a science advisory from the American Heart Association.

Arena R, Williams M, Forman DE, Cahalin LP, Coke L, Myers J, Hamm L, Kris-Etherton P, Humphrey R, Bittner V, Lavie CJ; American Heart Association Exercise, Cardiac Rehabilitation and Prevention Committee of the Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Council on Nutrition, Physical Activity and Metabolism.

Circulation. 2012 Mar 13;125(10):1321-9. doi: 10.1161/CIR.0b013e318246b1e5. Epub 2012 Jan 30. No abstract available.

PMID:
22291128
28.

Origin of a false positive urine pregnancy test in a patient with membranoproliferative glomerulonephritis type I.

Marzinke MA, Jarrar P, Atkinson M, Humphrey RL, Detrick B, Sokoll LJ.

Clin Chim Acta. 2012 Jan 18;413(1-2):361-3. doi: 10.1016/j.cca.2011.10.011. Epub 2011 Oct 15.

PMID:
22024216
29.

γ/IgG ratio: role in distinguishing monoclonal spikes from fibrinogen.

Lee MT, Caturegli P, Humphrey RL, Thompson RE, Detrick B.

J Clin Lab Anal. 2011;25(5):332-6. doi: 10.1002/jcla.20480.

30.

Opportunities and challenges in the development of experimental drug combinations for cancer.

Humphrey RW, Brockway-Lunardi LM, Bonk DT, Dohoney KM, Doroshow JH, Meech SJ, Ratain MJ, Topalian SL, Pardoll DM.

J Natl Cancer Inst. 2011 Aug 17;103(16):1222-6. doi: 10.1093/jnci/djr246. Epub 2011 Jul 15.

31.

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma.

Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH Jr, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD.

N Engl J Med. 2011 Jun 30;364(26):2517-26. doi: 10.1056/NEJMoa1104621. Epub 2011 Jun 5.

32.

Feasibility of vesicoamniotic shunt insertion in an inanimate model: comparison of fetoscopic and ultrasound-guided techniques.

Humphrey RJ, Grieci T, Schmidt J, Gagnon R, Han V, Bütter A.

Fetal Diagn Ther. 2011;30(1):48-52. doi: 10.1159/000323917. Epub 2011 Feb 24.

PMID:
21346321
33.

Development of ipilimumab: contribution to a new paradigm for cancer immunotherapy.

Hoos A, Ibrahim R, Korman A, Abdallah K, Berman D, Shahabi V, Chin K, Canetta R, Humphrey R.

Semin Oncol. 2010 Oct;37(5):533-46. doi: 10.1053/j.seminoncol.2010.09.015. Review.

PMID:
21074069
34.

Improved endpoints for cancer immunotherapy trials.

Hoos A, Eggermont AM, Janetzki S, Hodi FS, Ibrahim R, Anderson A, Humphrey R, Blumenstein B, Old L, Wolchok J.

J Natl Cancer Inst. 2010 Sep 22;102(18):1388-97. doi: 10.1093/jnci/djq310. Epub 2010 Sep 8. Review.

35.

Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells.

Humphrey RK, Newcomb CJ, Yu SM, Hao E, Yu D, Krajewski S, Du K, Jhala US.

J Biol Chem. 2010 Jul 16;285(29):22426-36. doi: 10.1074/jbc.M110.123786. Epub 2010 Apr 26.

36.

Digoxin immune fab treatment for severe preeclampsia.

Adair CD, Buckalew VM, Graves SW, Lam GK, Johnson DD, Saade G, Lewis DF, Robinson C, Danoff TM, Chauhan N, Hopoate-Sitake M, Porter KB, Humphrey RG, Trofatter KF, Amon E, Ward S, Kennedy L, Mason L, Johnston JA.

Am J Perinatol. 2010 Sep;27(8):655-62. doi: 10.1055/s-0030-1249762. Epub 2010 Mar 15.

PMID:
20232280
37.

Traumatic brain injury hospitalizations of U.S. army soldiers deployed to Afghanistan and Iraq.

Wojcik BE, Stein CR, Bagg K, Humphrey RJ, Orosco J.

Am J Prev Med. 2010 Jan;38(1 Suppl):S108-16. doi: 10.1016/j.amepre.2009.10.006.

PMID:
20117583
38.

Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study.

O'Day SJ, Maio M, Chiarion-Sileni V, Gajewski TF, Pehamberger H, Bondarenko IN, Queirolo P, Lundgren L, Mikhailov S, Roman L, Verschraegen C, Humphrey R, Ibrahim R, de Pril V, Hoos A, Wolchok JD.

Ann Oncol. 2010 Aug;21(8):1712-7. doi: 10.1093/annonc/mdq013. Epub 2010 Feb 10.

PMID:
20147741
39.

Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria.

Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbé C, Maio M, Binder M, Bohnsack O, Nichol G, Humphrey R, Hodi FS.

Clin Cancer Res. 2009 Dec 1;15(23):7412-20. doi: 10.1158/1078-0432.CCR-09-1624. Epub 2009 Nov 24.

40.

Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinases.

Humphrey RK, Yu SM, Flores LE, Jhala US.

J Biol Chem. 2010 Jan 29;285(5):3406-16. doi: 10.1074/jbc.M109.006734. Epub 2009 Oct 15.

41.

Immunohistochemical study of the phrenic ganglion.

Tubbs RS, Stetler W, Kelly DR, Blevins D, Lott R, Humphrey R, Shoja MM, Loukas M.

Anat Sci Int. 2008 Sep;83(3):159-61. doi: 10.1111/j.1447-073X.2007.00224.x.

PMID:
18956788
42.

U.S. Army disease and nonbattle injury model, refined in Afghanistan and Iraq.

Wojcik BE, Humphrey RJ, Czejdo B, Hassell LH.

Mil Med. 2008 Sep;173(9):825-35.

PMID:
18816921
43.

Laparoscopic compared with open adrenalectomy for resection of pheochromocytoma: a review of 47 cases.

Humphrey R, Gray D, Pautler S, Davies W.

Can J Surg. 2008 Aug;51(4):276-80.

44.

Comparison of Operation Iraqi Freedom and Patient Workload Generator injury distributions.

Wojcik BE, Humphrey RJ, Fulton LV, Psalmonds LC, Hassell LH.

Mil Med. 2008 Jul;173(7):647-52.

PMID:
18700598
45.

A monitoring programme for 1,3-dichloropropene and metabolites in groundwater in five EU countries.

Terry AS, Carter AD, Humphrey RL, Capri E, Grua B, Panagopoulous AC, Pulido-Bosch A, Kennedy SH.

Pest Manag Sci. 2008 Sep;64(9):923-32. doi: 10.1002/ps.1585.

PMID:
18398818
46.

Gamma heavy chain disease in a patient with diabetes and chronic renal insufficiency: diagnostic assessment of the heavy chain fragment.

Lee MT, Parwani A, Humphrey R, Hamilton RG, Myers DI, Detrick B.

J Clin Lab Anal. 2008;22(2):146-50. doi: 10.1002/jcla.20233.

47.

Epidermal growth factor abrogates hypoxia-induced apoptosis in cultured human trophoblasts through phosphorylation of BAD Serine 112.

Humphrey RG, Sonnenberg-Hirche C, Smith SD, Hu C, Barton A, Sadovsky Y, Nelson DM.

Endocrinology. 2008 May;149(5):2131-7. doi: 10.1210/en.2007-1253. Epub 2008 Feb 14.

48.

Predictable tissue integration and natural aesthetics using a zirconia CAD/CAM abutment and crowns.

Margeas R, Humphrey R.

Pract Proced Aesthet Dent. 2007 Nov-Dec;19(10):615-9. No abstract available.

PMID:
18246994
49.

Using a treadmill for the 6-minute walk test: reliability and validity.

Laskin JJ, Bundy S, Marron H, Moore H, Swanson M, Blair M, Humphrey R.

J Cardiopulm Rehabil Prev. 2007 Nov-Dec;27(6):407-10. doi: 10.1097/01.HCR.0000300270.45881.d0.

PMID:
18197077
50.

Recommended changes to oncology clinical trial design: revolution or evolution?

Ratain MJ, Humphrey RW, Gordon GB, Fyfe G, Adamson PC, Fleming TR, Stadler WM, Berry DA, Peck CC.

Eur J Cancer. 2008 Jan;44(1):8-11. Epub 2007 Nov 5. No abstract available.

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