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Items: 1 to 50 of 312

1.

Quantifying and Understanding Well-to-Well Contamination in Microbiome Research.

Minich JJ, Sanders JG, Amir A, Humphrey G, Gilbert JA, Knight R.

mSystems. 2019 Jun 25;4(4). pii: e00186-19. doi: 10.1128/mSystems.00186-19.

2.

The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances.

Regalado EL, Haidar Ahmad IA, Bennett R, D'Atri V, Makarov AA, Humphrey GR, Mangion I, Guillarme D.

Acc Chem Res. 2019 Jul 16;52(7):1990-2002. doi: 10.1021/acs.accounts.9b00068. Epub 2019 Jun 14.

PMID:
31198042
3.

The impact of skin care products on skin chemistry and microbiome dynamics.

Bouslimani A, da Silva R, Kosciolek T, Janssen S, Callewaert C, Amir A, Dorrestein K, Melnik AV, Zaramela LS, Kim JN, Humphrey G, Schwartz T, Sanders K, Brennan C, Luzzatto-Knaan T, Ackermann G, McDonald D, Zengler K, Knight R, Dorrestein PC.

BMC Biol. 2019 Jun 12;17(1):47. doi: 10.1186/s12915-019-0660-6.

4.

Triplicate PCR reactions for 16S rRNA gene amplicon sequencing are unnecessary.

Marotz C, Sharma A, Humphrey G, Gottel N, Daum C, Gilbert JA, Eloe-Fadrosh E, Knight R.

Biotechniques. 2019 Jul;67(1):29-32. doi: 10.2144/btn-2018-0192. Epub 2019 May 24.

5.

Scalable Synthesis of Diazeniumdiolates: Application to the Preparation of MK-8150.

Zhong YL, Weisel M, Humphrey GR, Muzzio DJ, Zhang L, Huffman MA, Zhong W, Maloney KM, Campos KR.

Org Lett. 2019 Jun 7;21(11):4210-4214. doi: 10.1021/acs.orglett.9b01401. Epub 2019 May 22.

PMID:
31117712
6.

Detection of smoking status from retinal images; a Convolutional Neural Network study.

Vaghefi E, Yang S, Hill S, Humphrey G, Walker N, Squirrell D.

Sci Rep. 2019 May 9;9(1):7180. doi: 10.1038/s41598-019-43670-0.

7.

Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems.

Tripathi A, Xu ZZ, Xue J, Poulsen O, Gonzalez A, Humphrey G, Meehan MJ, Melnik AV, Ackermann G, Zhou D, Malhotra A, Haddad GG, Dorrestein PC, Knight R.

mSystems. 2019 Apr 30;4(2). pii: e00058-19. doi: 10.1128/mSystems.00058-19. eCollection 2019 Mar-Apr.

8.

A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease.

Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu ZZ, Downes MR, Evans RM, Brenner DA, Sirlin CB, Knight R, Loomba R.

Nat Commun. 2019 Mar 29;10(1):1406. doi: 10.1038/s41467-019-09455-9.

9.

The genetic basis for adaptation of model-designed syntrophic co-cultures.

Lloyd CJ, King ZA, Sandberg TE, Hefner Y, Olson CA, Phaneuf PV, O'Brien EJ, Sanders JG, Salido RA, Sanders K, Brennan C, Humphrey G, Knight R, Feist AM.

PLoS Comput Biol. 2019 Mar 1;15(3):e1006213. doi: 10.1371/journal.pcbi.1006213. eCollection 2019 Mar.

10.

Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn's Disease.

Mills RH, Vázquez-Baeza Y, Zhu Q, Jiang L, Gaffney J, Humphrey G, Smarr L, Knight R, Gonzalez DJ.

mSystems. 2019 Feb 12;4(1). pii: e00337-18. doi: 10.1128/mSystems.00337-18. eCollection 2019 Jan-Feb.

11.

Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome.

Quinn RA, Adem S, Mills RH, Comstock W, DeRight Goldasich L, Humphrey G, Aksenov AA, Melnik AV, da Silva R, Ackermann G, Bandeira N, Gonzalez DJ, Conrad D, O'Donoghue AJ, Knight R, Dorrestein PC.

Microbiome. 2019 Feb 13;7(1):23. doi: 10.1186/s40168-019-0636-3.

12.

Impact of a smartphone app on prescriber adherence to antibiotic guidelines in adult patients with community acquired pneumonia or urinary tract infections.

Yoon CH, Ritchie SR, Duffy EJ, Thomas MG, McBride S, Read K, Chen R, Humphrey G.

PLoS One. 2019 Jan 29;14(1):e0211157. doi: 10.1371/journal.pone.0211157. eCollection 2019.

13.

High-Throughput Miniaturized 16S rRNA Amplicon Library Preparation Reduces Costs while Preserving Microbiome Integrity.

Minich JJ, Humphrey G, Benitez RAS, Sanders J, Swafford A, Allen EE, Knight R.

mSystems. 2018 Nov 6;3(6). pii: e00166-18. doi: 10.1128/mSystems.00166-18. eCollection 2018 Nov-Dec.

14.

Using codesign to develop a culturally tailored, behavior change mHealth intervention for indigenous and other priority communities: A case study in New Zealand.

Verbiest MEA, Corrigan C, Dalhousie S, Firestone R, Funaki T, Goodwin D, Grey J, Henry A, Humphrey G, Jull A, Vano M, Pekepo C, Morenga LT, Whittaker R, Mhurchu CN.

Transl Behav Med. 2018 Nov 2. doi: 10.1093/tbm/iby093. [Epub ahead of print]

PMID:
30388262
15.

Combining traditional 2D and modern physical organic-derived descriptors to predict enhanced enantioselectivity for the key aza-Michael conjugate addition in the synthesis of Prevymis™ (letermovir).

Metsänen TT, Lexa KW, Santiago CB, Chung CK, Xu Y, Liu Z, Humphrey GR, Ruck RT, Sherer EC, Sigman MS.

Chem Sci. 2018 Jul 18;9(34):6922-6927. doi: 10.1039/c8sc02089b. eCollection 2018 Sep 14.

16.

A Co-Designed, Culturally-Tailored mHealth Tool to Support Healthy Lifestyles in Māori and Pasifika Communities in New Zealand: Protocol for a Cluster Randomized Controlled Trial.

Verbiest M, Borrell S, Dalhousie S, Tupa'i-Firestone R, Funaki T, Goodwin D, Grey J, Henry A, Hughes E, Humphrey G, Jiang Y, Jull A, Pekepo C, Schumacher J, Te Morenga L, Tunks M, Vano M, Whittaker R, Ni Mhurchu C.

JMIR Res Protoc. 2018 Aug 22;7(8):e10789. doi: 10.2196/10789.

17.
18.

Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes.

Amato KR, G Sanders J, Song SJ, Nute M, Metcalf JL, Thompson LR, Morton JT, Amir A, J McKenzie V, Humphrey G, Gogul G, Gaffney J, L Baden A, A O Britton G, P Cuozzo F, Di Fiore A, J Dominy N, L Goldberg T, Gomez A, Kowalewski MM, J Lewis R, Link A, L Sauther M, Tecot S, A White B, E Nelson K, M Stumpf R, Knight R, R Leigh S.

ISME J. 2019 Mar;13(3):576-587. doi: 10.1038/s41396-018-0175-0. Epub 2018 Jul 11.

PMID:
29995839
19.

Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome.

Tripathi A, Melnik AV, Xue J, Poulsen O, Meehan MJ, Humphrey G, Jiang L, Ackermann G, McDonald D, Zhou D, Knight R, Dorrestein PC, Haddad GG.

mSystems. 2018 Jun 5;3(3). pii: e00020-18. doi: 10.1128/mSystems.00020-18. eCollection 2018 May-Jun.

20.

American Gut: an Open Platform for Citizen Science Microbiome Research.

McDonald D, Hyde E, Debelius JW, Morton JT, Gonzalez A, Ackermann G, Aksenov AA, Behsaz B, Brennan C, Chen Y, DeRight Goldasich L, Dorrestein PC, Dunn RR, Fahimipour AK, Gaffney J, Gilbert JA, Gogul G, Green JL, Hugenholtz P, Humphrey G, Huttenhower C, Jackson MA, Janssen S, Jeste DV, Jiang L, Kelley ST, Knights D, Kosciolek T, Ladau J, Leach J, Marotz C, Meleshko D, Melnik AV, Metcalf JL, Mohimani H, Montassier E, Navas-Molina J, Nguyen TT, Peddada S, Pevzner P, Pollard KS, Rahnavard G, Robbins-Pianka A, Sangwan N, Shorenstein J, Smarr L, Song SJ, Spector T, Swafford AD, Thackray VG, Thompson LR, Tripathi A, Vázquez-Baeza Y, Vrbanac A, Wischmeyer P, Wolfe E, Zhu Q; American Gut Consortium , Knight R.

mSystems. 2018 May 15;3(3). pii: e00031-18. doi: 10.1128/mSystems.00031-18. eCollection 2018 May-Jun.

21.

Exposure to toxic metals triggers unique responses from the rat gut microbiota.

Richardson JB, Dancy BCR, Horton CL, Lee YS, Madejczyk MS, Xu ZZ, Ackermann G, Humphrey G, Palacios G, Knight R, Lewis JA.

Sci Rep. 2018 Apr 26;8(1):6578. doi: 10.1038/s41598-018-24931-w.

22.

A communal catalogue reveals Earth's multiscale microbial diversity.

Thompson LR, Sanders JG, McDonald D, Amir A, Ladau J, Locey KJ, Prill RJ, Tripathi A, Gibbons SM, Ackermann G, Navas-Molina JA, Janssen S, Kopylova E, Vázquez-Baeza Y, González A, Morton JT, Mirarab S, Zech Xu Z, Jiang L, Haroon MF, Kanbar J, Zhu Q, Jin Song S, Kosciolek T, Bokulich NA, Lefler J, Brislawn CJ, Humphrey G, Owens SM, Hampton-Marcell J, Berg-Lyons D, McKenzie V, Fierer N, Fuhrman JA, Clauset A, Stevens RL, Shade A, Pollard KS, Goodwin KD, Jansson JK, Gilbert JA, Knight R; Earth Microbiome Project Consortium.

Nature. 2017 Nov 23;551(7681):457-463. doi: 10.1038/nature24621. Epub 2017 Nov 1.

23.

Three-Dimensional Microbiome and Metabolome Cartography of a Diseased Human Lung.

Garg N, Wang M, Hyde E, da Silva RR, Melnik AV, Protsyuk I, Bouslimani A, Lim YW, Wong R, Humphrey G, Ackermann G, Spivey T, Brouha SS, Bandeira N, Lin GY, Rohwer F, Conrad DJ, Alexandrov T, Knight R, Dorrestein PC.

Cell Host Microbe. 2017 Nov 8;22(5):705-716.e4. doi: 10.1016/j.chom.2017.10.001. Epub 2017 Oct 19.

24.

Asymmetric Synthesis of Functionalized trans-Cyclopropoxy Building Block for Grazoprevir.

Xu F, Zhong YL, Li H, Qi J, Desmond R, Song ZJ, Park J, Wang T, Truppo M, Humphrey GR, Ruck RT.

Org Lett. 2017 Nov 3;19(21):5880-5883. doi: 10.1021/acs.orglett.7b02867.

PMID:
29052413
25.

Asymmetric Hydrogen Bonding Catalysis for the Synthesis of Dihydroquinazoline-Containing Antiviral, Letermovir.

Chung CK, Liu Z, Lexa KW, Andreani T, Xu Y, Ji Y, DiRocco DA, Humphrey GR, Ruck RT.

J Am Chem Soc. 2017 Aug 9;139(31):10637-10640. doi: 10.1021/jacs.7b05806. Epub 2017 Jul 25.

PMID:
28737937
26.

DNA extraction for streamlined metagenomics of diverse environmental samples.

Marotz C, Amir A, Humphrey G, Gaffney J, Gogul G, Knight R.

Biotechniques. 2017 Jun 1;62(6):290-293. doi: 10.2144/000114559.

27.

The Oral and Skin Microbiomes of Captive Komodo Dragons Are Significantly Shared with Their Habitat.

Hyde ER, Navas-Molina JA, Song SJ, Kueneman JG, Ackermann G, Cardona C, Humphrey G, Boyer D, Weaver T, Mendelson JR 3rd, McKenzie VJ, Gilbert JA, Knight R.

mSystems. 2016 Aug 2;1(4). pii: e00046-16. eCollection 2016 Jul-Aug.

28.

Preservation Methods Differ in Fecal Microbiome Stability, Affecting Suitability for Field Studies.

Song SJ, Amir A, Metcalf JL, Amato KR, Xu ZZ, Humphrey G, Knight R.

mSystems. 2016 May 3;1(3). pii: e00021-16. eCollection 2016 May-Jun.

29.

From Sample to Multi-Omics Conclusions in under 48 Hours.

Quinn RA, Navas-Molina JA, Hyde ER, Song SJ, Vázquez-Baeza Y, Humphrey G, Gaffney J, Minich JJ, Melnik AV, Herschend J, DeReus J, Durant A, Dutton RJ, Khosroheidari M, Green C, da Silva R, Dorrestein PC, Knight R.

mSystems. 2016 Apr 26;1(2). pii: e00038-16. eCollection 2016 Mar-Apr.

30.

Improved Bacterial 16S rRNA Gene (V4 and V4-5) and Fungal Internal Transcribed Spacer Marker Gene Primers for Microbial Community Surveys.

Walters W, Hyde ER, Berg-Lyons D, Ackermann G, Humphrey G, Parada A, Gilbert JA, Jansson JK, Caporaso JG, Fuhrman JA, Apprill A, Knight R.

mSystems. 2015 Dec 22;1(1). pii: e00009-15. eCollection 2016 Jan-Feb.

31.

Asymmetric Synthesis of a Potent HIV-1 Integrase Inhibitor.

Kuethe JT, Humphrey GR, Journet M, Peng Z, Childers KG.

J Org Chem. 2016 Nov 4;81(21):10256-10265. Epub 2016 Aug 10.

PMID:
27471910
32.

Parental smoking during pregnancy: findings from the Growing Up in New Zealand cohort.

Humphrey G, Rossen F, Walker N, Bullen C.

N Z Med J. 2016 Sep 23;129(1442):60-74.

PMID:
27657160
33.

Development of Risk-Taking, Perspective-Taking, and Inhibitory Control During Adolescence.

Humphrey G, Dumontheil I.

Dev Neuropsychol. 2016 Jan-Mar;41(1-2):59-76. doi: 10.1080/87565641.2016.1161764. Epub 2016 Apr 12.

PMID:
27070826
34.

A Synthesis of a Spirocyclic Macrocyclic Protease Inhibitor for the Treatment of Hepatitis C.

Chung CK, Cleator E, Dumas AM, Hicks JD, Humphrey GR, Maligres PE, Nolting AF, Rivera N, Ruck RT, Shevlin M.

Org Lett. 2016 Mar 18;18(6):1394-7. doi: 10.1021/acs.orglett.6b00331. Epub 2016 Mar 7.

PMID:
26950496
35.

Angiomyxoma in Accessory Hepatic Lobe.

Rossi A, Pederiva F, Santos R, Wood S, Humphrey G.

APSP J Case Rep. 2016 Jan 1;7(1):10. eCollection 2016 Jan-Apr. No abstract available.

36.

Microbial community assembly and metabolic function during mammalian corpse decomposition.

Metcalf JL, Xu ZZ, Weiss S, Lax S, Van Treuren W, Hyde ER, Song SJ, Amir A, Larsen P, Sangwan N, Haarmann D, Humphrey GC, Ackermann G, Thompson LR, Lauber C, Bibat A, Nicholas C, Gebert MJ, Petrosino JF, Reed SC, Gilbert JA, Lynne AM, Bucheli SR, Carter DO, Knight R.

Science. 2016 Jan 8;351(6269):158-62. doi: 10.1126/science.aad2646. Epub 2015 Dec 10.

37.

Phylogenetic and ecological factors impact the gut microbiota of two Neotropical primate species.

Amato KR, Martinez-Mota R, Righini N, Raguet-Schofield M, Corcione FP, Marini E, Humphrey G, Gogul G, Gaffney J, Lovelace E, Williams L, Luong A, Dominguez-Bello MG, Stumpf RM, White B, Nelson KE, Knight R, Leigh SR.

Oecologia. 2016 Mar;180(3):717-33. doi: 10.1007/s00442-015-3507-z. Epub 2015 Nov 24.

PMID:
26597549
38.

Gram-negative organisms in peritoneal dialysis peritonitis: an early indication for surgery in patients with haemolytic uraemic syndrome?

Harwood R, Wilkinson D, Ramkumar S, Humphrey G.

Pediatr Surg Int. 2016 Mar;32(3):235-8. doi: 10.1007/s00383-015-3833-6. Epub 2015 Nov 17.

PMID:
26578260
39.

Highly efficient synthesis of HIV NNRTI doravirine.

Gauthier DR Jr, Sherry BD, Cao Y, Journet M, Humphrey G, Itoh T, Mangion I, Tschaen DM.

Org Lett. 2015 Mar 20;17(6):1353-6. doi: 10.1021/ol503625z. Epub 2015 Mar 9.

PMID:
25751537
40.

Lung biopsy for chronic pulmonary disease in children.

Greenhalgh RM, Yardley IE, Child F, Bruce J, Humphrey GM.

J Pediatr Surg. 2014 Jul;49(7):1075-7. doi: 10.1016/j.jpedsurg.2013.10.026. Epub 2013 Nov 15.

PMID:
24952791
41.

The power of persuasion.

Humphrey GB.

Narrat Inq Bioeth. 2013 Fall;3(2):101-3. doi: 10.1353/nib.2013.0030. No abstract available.

PMID:
24407075
42.

The many faces of moral distress among clinicians.

Rushton CH, Boss R, Hallett K, Hensel J, Humphrey GB, Les J, Mack C, McCammon S, Murray JS, Nathanson E, Pniewski J, Shuham AM, Volpe RL.

Narrat Inq Bioeth. 2013 Fall;3(2):89-93. doi: 10.1353/nib.2013.0039.

PMID:
24407071
43.

Why a shared care record is an official medical record.

Gu Y, Orr M, Warren J, Humphrey G, Day K, Tibby S, Fitzpatrick J.

N Z Med J. 2013 Oct 18;126(1384):109-17.

PMID:
24162635
44.

A microbial clock provides an accurate estimate of the postmortem interval in a mouse model system.

Metcalf JL, Wegener Parfrey L, Gonzalez A, Lauber CL, Knights D, Ackermann G, Humphrey GC, Gebert MJ, Van Treuren W, Berg-Lyons D, Keepers K, Guo Y, Bullard J, Fierer N, Carter DO, Knight R.

Elife. 2013 Oct 15;2:e01104. doi: 10.7554/eLife.01104.

45.

Ventriculoperitoneal shunt survival in children who require additional abdominal surgery--are our estimations of the additional risk accurate?

Li Ching A, Humphrey G, Kamaly-Asl ID.

Br J Neurosurg. 2014 Jan;28(1):40-8. doi: 10.3109/02688697.2013.815322. Epub 2013 Sep 11.

PMID:
24024873
46.

Development of a practical, asymmetric synthesis of the hepatitis C virus protease inhibitor MK-5172.

Kuethe J, Zhong YL, Yasuda N, Beutner G, Linn K, Kim M, Marcune B, Dreher SD, Humphrey G, Pei T.

Org Lett. 2013 Aug 16;15(16):4174-7. doi: 10.1021/ol401864t. Epub 2013 Aug 6.

PMID:
23919347
47.

Cohabiting family members share microbiota with one another and with their dogs.

Song SJ, Lauber C, Costello EK, Lozupone CA, Humphrey G, Berg-Lyons D, Caporaso JG, Knights D, Clemente JC, Nakielny S, Gordon JI, Fierer N, Knight R.

Elife. 2013 Apr 16;2:e00458. doi: 10.7554/eLife.00458.

48.

Cytoplasmic free Ca2+ is essential for multiple steps in malaria parasite egress from infected erythrocytes.

Glushakova S, Lizunov V, Blank PS, Melikov K, Humphrey G, Zimmerberg J.

Malar J. 2013 Jan 30;12:41. doi: 10.1186/1475-2875-12-41.

49.

Usage analysis of a shared care planning system.

Warren J, Gu Y, Humphrey G.

AMIA Annu Symp Proc. 2012;2012:950-9. Epub 2012 Nov 3.

50.

Pneumonectomy: The final cut in a rare incidence of persistent bronchopleural fistula following empyema.

Peters RT, Child F, Long AM, Humphrey GM, Rakoczy G.

Pediatr Pulmonol. 2013 Jun;48(6):617-21. doi: 10.1002/ppul.22649. Epub 2012 Aug 21.

PMID:
22911950

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