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Items: 1 to 50 of 81

1.

Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.

Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen RS, Stehling-Sun S, Sabo PJ, Byron R, Humbert R, Thurman RE, Johnson AK, Vong S, Lee K, Bates D, Neri F, Diegel M, Giste E, Haugen E, Dunn D, Wilken MS, Josefowicz S, Samstein R, Chang KH, Eichler EE, De Bruijn M, Reh TA, Skoultchi A, Rudensky A, Orkin SH, Papayannopoulou T, Treuting PM, Selleri L, Kaul R, Groudine M, Bender MA, Stamatoyannopoulos JA.

Science. 2014 Nov 21;346(6212):1007-12. doi: 10.1126/science.1246426.

2.

A comparative encyclopedia of DNA elements in the mouse genome.

Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, Rynes E, Kirilusha A, Marinov GK, Williams BA, Trout D, Amrhein H, Fisher-Aylor K, Antoshechkin I, DeSalvo G, See LH, Fastuca M, Drenkow J, Zaleski C, Dobin A, Prieto P, Lagarde J, Bussotti G, Tanzer A, Denas O, Li K, Bender MA, Zhang M, Byron R, Groudine MT, McCleary D, Pham L, Ye Z, Kuan S, Edsall L, Wu YC, Rasmussen MD, Bansal MS, Kellis M, Keller CA, Morrissey CS, Mishra T, Jain D, Dogan N, Harris RS, Cayting P, Kawli T, Boyle AP, Euskirchen G, Kundaje A, Lin S, Lin Y, Jansen C, Malladi VS, Cline MS, Erickson DT, Kirkup VM, Learned K, Sloan CA, Rosenbloom KR, Lacerda de Sousa B, Beal K, Pignatelli M, Flicek P, Lian J, Kahveci T, Lee D, Kent WJ, Ramalho Santos M, Herrero J, Notredame C, Johnson A, Vong S, Lee K, Bates D, Neri F, Diegel M, Canfield T, Sabo PJ, Wilken MS, Reh TA, Giste E, Shafer A, Kutyavin T, Haugen E, Dunn D, Reynolds AP, Neph S, Humbert R, Hansen RS, De Bruijn M, Selleri L, Rudensky A, Josefowicz S, Samstein R, Eichler EE, Orkin SH, Levasseur D, Papayannopoulou T, Chang KH, Skoultchi A, Gosh S, Disteche C, Treuting P, Wang Y, Weiss MJ, Blobel GA, Cao X, Zhong S, Wang T, Good PJ, Lowdon RF, Adams LB, Zhou XQ, Pazin MJ, Feingold EA, Wold B, Taylor J, Mortazavi A, Weissman SM, Stamatoyannopoulos JA, Snyder MP, Guigo R, Gingeras TR, Gilbert DM, Hardison RC, Beer MA, Ren B; Mouse ENCODE Consortium.

Nature. 2014 Nov 20;515(7527):355-64. doi: 10.1038/nature13992.

3.

Developmental fate and cellular maturity encoded in human regulatory DNA landscapes.

Stergachis AB, Neph S, Reynolds A, Humbert R, Miller B, Paige SL, Vernot B, Cheng JB, Thurman RE, Sandstrom R, Haugen E, Heimfeld S, Murry CE, Akey JM, Stamatoyannopoulos JA.

Cell. 2013 Aug 15;154(4):888-903. doi: 10.1016/j.cell.2013.07.020.

4.

[Use of oral oxybutynin at 7.5 mg per day in primary hyperhidrosis].

Try C, Messikh R, Elkhyat A, Aubin F, Humbert RP.

Rev Med Liege. 2012 Oct;67(10):520-6. French.

5.

Systematic localization of common disease-associated variation in regulatory DNA.

Maurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, Wang H, Reynolds AP, Sandstrom R, Qu H, Brody J, Shafer A, Neri F, Lee K, Kutyavin T, Stehling-Sun S, Johnson AK, Canfield TK, Giste E, Diegel M, Bates D, Hansen RS, Neph S, Sabo PJ, Heimfeld S, Raubitschek A, Ziegler S, Cotsapas C, Sotoodehnia N, Glass I, Sunyaev SR, Kaul R, Stamatoyannopoulos JA.

Science. 2012 Sep 7;337(6099):1190-5. doi: 10.1126/science.1222794. Epub 2012 Sep 5.

6.

An expansive human regulatory lexicon encoded in transcription factor footprints.

Neph S, Vierstra J, Stergachis AB, Reynolds AP, Haugen E, Vernot B, Thurman RE, John S, Sandstrom R, Johnson AK, Maurano MT, Humbert R, Rynes E, Wang H, Vong S, Lee K, Bates D, Diegel M, Roach V, Dunn D, Neri J, Schafer A, Hansen RS, Kutyavin T, Giste E, Weaver M, Canfield T, Sabo P, Zhang M, Balasundaram G, Byron R, MacCoss MJ, Akey JM, Bender MA, Groudine M, Kaul R, Stamatoyannopoulos JA.

Nature. 2012 Sep 6;489(7414):83-90. doi: 10.1038/nature11212.

7.

The accessible chromatin landscape of the human genome.

Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, John S, Sandstrom R, Bates D, Boatman L, Canfield TK, Diegel M, Dunn D, Ebersol AK, Frum T, Giste E, Johnson AK, Johnson EM, Kutyavin T, Lajoie B, Lee BK, Lee K, London D, Lotakis D, Neph S, Neri F, Nguyen ED, Qu H, Reynolds AP, Roach V, Safi A, Sanchez ME, Sanyal A, Shafer A, Simon JM, Song L, Vong S, Weaver M, Yan Y, Zhang Z, Zhang Z, Lenhard B, Tewari M, Dorschner MO, Hansen RS, Navas PA, Stamatoyannopoulos G, Iyer VR, Lieb JD, Sunyaev SR, Akey JM, Sabo PJ, Kaul R, Furey TS, Dekker J, Crawford GE, Stamatoyannopoulos JA.

Nature. 2012 Sep 6;489(7414):75-82. doi: 10.1038/nature11232.

8.

BEDOPS: high-performance genomic feature operations.

Neph S, Kuehn MS, Reynolds AP, Haugen E, Thurman RE, Johnson AK, Rynes E, Maurano MT, Vierstra J, Thomas S, Sandstrom R, Humbert R, Stamatoyannopoulos JA.

Bioinformatics. 2012 Jul 15;28(14):1919-20. doi: 10.1093/bioinformatics/bts277. Epub 2012 May 9.

9.

Gammaretroviral vector integration occurs overwhelmingly within and near DNase hypersensitive sites.

Liu M, Li CL, Stamatoyannopoulos G, Dorschner MO, Humbert R, Stamatoyannopoulos JA, Emery DW.

Hum Gene Ther. 2012 Feb;23(2):231-7. doi: 10.1089/hum.2010.177. Epub 2011 Dec 14.

10.

A thermodynamic approach to PCR primer design.

Mann T, Humbert R, Dorschner M, Stamatoyannopoulos J, Noble WS.

Nucleic Acids Res. 2009 Jul;37(13):e95. doi: 10.1093/nar/gkp443. Epub 2009 Jun 15.

11.

Assaying the regulatory potential of mammalian conserved non-coding sequences in human cells.

Attanasio C, Reymond A, Humbert R, Lyle R, Kuehn MS, Neph S, Sabo PJ, Goldy J, Weaver M, Haydock A, Lee K, Dorschner M, Dermitzakis ET, Antonarakis SE, Stamatoyannopoulos JA.

Genome Biol. 2008;9(12):R168. doi: 10.1186/gb-2008-9-12-r168. Epub 2008 Dec 2.

12.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA; NISC Comparative Sequencing Program; Baylor College of Medicine Human Genome Sequencing Center; Washington University Genome Sequencing Center; Broad Institute; Children's Hospital Oakland Research Institute, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith K, Thakkapallayil A, Barber G, Kuhn RM, Karolchik D, Armengol L, Bird CP, de Bakker PI, Kern AD, Lopez-Bigas N, Martin JD, Stranger BE, Woodroffe A, Davydov E, Dimas A, Eyras E, Hallgrímsdóttir IB, Huppert J, Zody MC, Abecasis GR, Estivill X, Bouffard GG, Guan X, Hansen NF, Idol JR, Maduro VV, Maskeri B, McDowell JC, Park M, Thomas PJ, Young AC, Blakesley RW, Muzny DM, Sodergren E, Wheeler DA, Worley KC, Jiang H, Weinstock GM, Gibbs RA, Graves T, Fulton R, Mardis ER, Wilson RK, Clamp M, Cuff J, Gnerre S, Jaffe DB, Chang JL, Lindblad-Toh K, Lander ES, Koriabine M, Nefedov M, Osoegawa K, Yoshinaga Y, Zhu B, de Jong PJ.

Nature. 2007 Jun 14;447(7146):799-816.

13.

Automated validation of polymerase chain reaction amplicon melting curves.

Mann TP, Humbert R, Stamatoyannopolous JA, Noble WS.

J Bioinform Comput Biol. 2006 Apr;4(2):299-315.

PMID:
16819785
14.

Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays.

Sabo PJ, Kuehn MS, Thurman R, Johnson BE, Johnson EM, Cao H, Yu M, Rosenzweig E, Goldy J, Haydock A, Weaver M, Shafer A, Lee K, Neri F, Humbert R, Singer MA, Richmond TA, Dorschner MO, McArthur M, Hawrylycz M, Green RD, Navas PA, Noble WS, Stamatoyannopoulos JA.

Nat Methods. 2006 Jul;3(7):511-8.

PMID:
16791208
15.

Automated validation of polymerase chain reactions using amplicon melting curves.

Mann TP, Humbert R, Stamatoyannopolous JA, Noble WS.

Proc IEEE Comput Syst Bioinform Conf. 2005:377-85.

PMID:
16447995
16.

[Management of patients admitted for acute myocardial infarction in France from 1995 to 2000: time to admission dependent improvement in outcome].

Danchin N, Kadri Z, Cambou JP, Hanania G, Humbert R, Clerson P, Vaur L, Guéret P, Blanchard D, Genès N, Lablanche JM; investigateurs USIK 1995 et USIC 2000.

Arch Mal Coeur Vaiss. 2005 Nov;98(11):1149-54. French.

PMID:
16379113
17.

High-throughput localization of functional elements by quantitative chromatin profiling.

Dorschner MO, Hawrylycz M, Humbert R, Wallace JC, Shafer A, Kawamoto J, Mack J, Hall R, Goldy J, Sabo PJ, Kohli A, Li Q, McArthur M, Stamatoyannopoulos JA.

Nat Methods. 2004 Dec;1(3):219-25. Epub 2004 Nov 18.

PMID:
15782197
18.

Discovery of functional noncoding elements by digital analysis of chromatin structure.

Sabo PJ, Hawrylycz M, Wallace JC, Humbert R, Yu M, Shafer A, Kawamoto J, Hall R, Mack J, Dorschner MO, McArthur M, Stamatoyannopoulos JA.

Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16837-42. Epub 2004 Nov 18.

19.

Management and in-hospital outcome of patients with acute myocardial infarction admitted to intensive care units at the turn of the century: results from the French nationwide USIC 2000 registry.

Hanania G, Cambou JP, Guéret P, Vaur L, Blanchard D, Lablanche JM, Boutalbi Y, Humbert R, Clerson P, Genès N, Danchin N; USIC 2000 Investigators.

Heart. 2004 Dec;90(12):1404-10.

20.

Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries.

Sabo PJ, Humbert R, Hawrylycz M, Wallace JC, Dorschner MO, McArthur M, Stamatoyannopoulos JA.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4537-42. Epub 2004 Mar 19.

21.

[Evolution of the management and outcomes of patients admitted for acute myocardial infarction in France from 1995 to 2000: data from the USIK 1995 and USIC 2000 nationwide registries].

Cambou JP, Danchin N, Boutalbi Y, Hanania G, Humbert R, Clerson P, Vaur L, Guéret P, Blanchard D, Genès N, Lablanche JM; Investigateurs USIK 1995 et USIC 2000.

Ann Cardiol Angeiol (Paris). 2004 Jan;53(1):12-7. French.

PMID:
15038522
22.

[Handipark: a simple test of the impact of Parkinson's disease on activities of daily living].

Ziégler M, de Broucker T, Damier P, Humbert R, Clerson P, Richard-Berthe C.

Rev Neurol (Paris). 2003 Sep;159(8-9):767-74. French.

PMID:
13679719
23.

[Descriptive epidemiological study of acne on scholar pupils in France during autumn 1996].

Daniel F, Dreno B, Poli F, Auffret N, Beylot C, Bodokh I, Chivot M, Humbert P, Meynadier J, Clerson P, Humbert R, Berrou JP, Dropsy R.

Ann Dermatol Venereol. 2000 Mar;127(3):273-8. French.

24.

[National survey on the use of induced labor by obstetricians. Study Group on Induced Labor].

Goffinet F, Humbert R, Clerson P, Philippe HJ, Bréart G, Cabrol D.

J Gynecol Obstet Biol Reprod (Paris). 1999 Jul;28(4):319-29. French.

25.

Paraoxonase genotypes, lipoprotein lipase activity, and HDL.

Nevin DN, Zambon A, Furlong CE, Richter RJ, Humbert R, Hokanson JE, Brunzell JD.

Arterioscler Thromb Vasc Biol. 1996 Oct;16(10):1243-9.

PMID:
8857920
26.

Structural organization of the human PON1 gene.

Clendenning JB, Humbert R, Green ED, Wood C, Traver D, Furlong CE.

Genomics. 1996 Aug 1;35(3):586-9.

PMID:
8812495
27.

[Effects of bisoprolol and ramipril on short-term variability of systolic blood pressure during mental stress test: spectrum analysis].

Elkohen M, Clerson P, Mounier-Véhier C, Gressin V, Humbert R, Carré A.

Arch Mal Coeur Vaiss. 1995 Aug;88(8):1075-80. French.

PMID:
8572849
28.

[Stress, blood pressure reactivity and arterial hypertension: not an unambiguous relation].

Clerson P, Elkohen M, Mounier-Véhier C, Humbert R, Jouvent R, Prost PL, Carré A.

Arch Mal Coeur Vaiss. 1994 Aug;87(8):1097-101. French.

PMID:
7755467
29.

[Blood pressure variability and stimulation tests: value of the Stroop word color conflict test].

Elkohen M, Clerson P, Mounier-Véhier CL, Humbert R, Prost PL, Poncelet P, Carré A.

Arch Mal Coeur Vaiss. 1994 Aug;87(8):1073-7. French.

PMID:
7755462
30.

Dynamics and structures of DNA: long-range effects of a 16 base-pair (CG)8 sequence on secondary structure.

Kim US, Fujimoto BS, Furlong CE, Sundstrom JA, Humbert R, Teller DC, Schurr JM.

Biopolymers. 1993 Nov;33(11):1725-45.

PMID:
8241430
31.

The molecular basis of the human serum paraoxonase activity polymorphism.

Humbert R, Adler DA, Disteche CM, Hassett C, Omiecinski CJ, Furlong CE.

Nat Genet. 1993 Jan;3(1):73-6.

PMID:
8098250
32.

Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence.

Hassett C, Richter RJ, Humbert R, Chapline C, Crabb JW, Omiecinski CJ, Furlong CE.

Biochemistry. 1991 Oct 22;30(42):10141-9.

PMID:
1657140
35.

Plasma oxytocin increases in the human sexual response.

Carmichael MS, Humbert R, Dixen J, Palmisano G, Greenleaf W, Davidson JM.

J Clin Endocrinol Metab. 1987 Jan;64(1):27-31.

PMID:
3782434
36.

Escherichia coli mutants defective in the uncH gene.

Humbert R, Brusilow WS, Gunsalus RP, Klionsky DJ, Simoni RD.

J Bacteriol. 1983 Jan;153(1):416-22.

37.
39.

Sporulation and heat resistance of Bacillus stearothermophilus spores produced in chemically defined media.

De Guzman A, Fields ML, Humbert RD, Kazanas N.

J Bacteriol. 1972 May;110(2):775-6.

40.

Studies on variants of Bacillus stearothermophilus strain NCA 1518.

Humbert RD, DeGuzman A, Fields ML.

Appl Microbiol. 1972 Apr;23(4):693-8.

41.
42.

[GEORGES BOURGUIGNON (1876-1963)].

HUMBERT R.

J Radiol Electrol Med Nucl. 1963 Aug-Sep;44:553-4. French. No abstract available.

PMID:
14053327
43.

[Electromyography and electrodiagnosis].

HUMBERT R, TARDIVEAU J, GUIHARD R, GUIHARD D, BONNARD J.

J Radiol Electrol Med Nucl. 1962 Mar-Apr;43:167-78. French. No abstract available.

PMID:
14036449
44.

[Electromyographic study of the pseudo-aspects of muscular degeneration occasionally observed after cortical lesions].

HUMBERT R, LAGET P, GUIHARD D.

C R Hebd Seances Acad Sci. 1960 May 23;250:3539-40. French. No abstract available.

PMID:
14403982
45.

[New research on the mechanisms of myotonic contaction].

HUMBERT R, DEHOUVE A, LAGET P, GUIHARD D.

Rev Neurol (Paris). 1960 Apr;102:330-3. French. No abstract available.

PMID:
13716786
46.

[Typhosis and Salmonella gastroenteritis].

HUMBERT R, MANNWEILER E, SIEMENS W.

Dtsch Med Wochenschr. 1960 Jan 29;85:185-92. German. No abstract available.

PMID:
14403981
47.

[Diagnosis and therapy of chronic Salmonella excretors; report of 100 patients].

HUMBERT R.

Dtsch Med Wochenschr. 1959 Apr 10;84(15):742-4 passim. German. No abstract available.

PMID:
13639722
48.

[Treatment of ulcerative colitis].

HUMBERT R.

Ther Ggw. 1959 Mar;98(3):128-30. German. No abstract available.

PMID:
13647490
49.

[Retardation of muscular contraction; electromyographic study by remote control stimulation].

HUMBERT R, DEHOUVE A, LAGET P.

J Radiol Electrol Arch Electr Medicale. 1958 Nov;39(11):737-41. French. No abstract available.

PMID:
13611742
50.

[Immediate & late sequels in febrile convulsions in children under 4].

LAPLANE R, HUMBERT R, LAGET P, SALBREUX R, DEBRAY P.

Rev Neurol (Paris). 1958 Jul;99(1):26-38. French. No abstract available.

PMID:
13624383

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