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Items: 22


Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins.

Jemth P, Karlsson E, Vögeli B, Guzovsky B, Andersson E, Hultqvist G, Dogan J, Güntert P, Riek R, Chi CN.

Sci Adv. 2018 Oct 24;4(10):eaau4130. doi: 10.1126/sciadv.aau4130. eCollection 2018 Oct.


High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain.

Fang XT, Hultqvist G, Meier SR, Antoni G, Sehlin D, Syvänen S.

Neuroimage. 2019 Jan 1;184:881-888. doi: 10.1016/j.neuroimage.2018.10.011. Epub 2018 Oct 6.


Blood-brain barrier integrity in a mouse model of Alzheimer's disease with or without acute 3D6 immunotherapy.

Gustafsson S, Gustavsson T, Roshanbin S, Hultqvist G, Hammarlund-Udenaes M, Sehlin D, Syvänen S.

Neuropharmacology. 2018 Dec;143:1-9. doi: 10.1016/j.neuropharm.2018.09.001. Epub 2018 Sep 7.


Antibody-Based In Vivo PET Imaging Detects Amyloid-β Reduction in Alzheimer Transgenic Mice After BACE-1 Inhibition.

Meier SR, Syvänen S, Hultqvist G, Fang XT, Roshanbin S, Lannfelt L, Neumann U, Sehlin D.

J Nucl Med. 2018 Dec;59(12):1885-1891. doi: 10.2967/jnumed.118.213140. Epub 2018 May 31.


Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.

Syvänen S, Hultqvist G, Gustavsson T, Gumucio A, Laudon H, Söderberg L, Ingelsson M, Lannfelt L, Sehlin D.

Alzheimers Res Ther. 2018 May 24;10(1):49. doi: 10.1186/s13195-018-0377-8.


Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells.

Fang XT, Sehlin D, Lannfelt L, Syvänen S, Hultqvist G.

Biol Proced Online. 2017 Sep 15;19:11. doi: 10.1186/s12575-017-0060-7. eCollection 2017.


Evolution of the p53-MDM2 pathway.

Åberg E, Saccoccia F, Grabherr M, Ore WYJ, Jemth P, Hultqvist G.

BMC Evol Biol. 2017 Aug 3;17(1):177. doi: 10.1186/s12862-017-1023-y.


Emergence and evolution of an interaction between intrinsically disordered proteins.

Hultqvist G, Åberg E, Camilloni C, Sundell GN, Andersson E, Dogan J, Chi CN, Vendruscolo M, Jemth P.

Elife. 2017 Apr 11;6. pii: e16059. doi: 10.7554/eLife.16059.


A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging.

Syvänen S, Fang XT, Hultqvist G, Meier SR, Lannfelt L, Sehlin D.

Neuroimage. 2017 Mar 1;148:55-63. doi: 10.1016/j.neuroimage.2017.01.004. Epub 2017 Jan 6.


Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor.

Hultqvist G, Syvänen S, Fang XT, Lannfelt L, Sehlin D.

Theranostics. 2017 Jan 1;7(2):308-318. doi: 10.7150/thno.17155. eCollection 2017.


The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain.

Pedersen SW, Hultqvist G, Strømgaard K, Jemth P.

PLoS One. 2014 Apr 18;9(4):e95619. doi: 10.1371/journal.pone.0095619. eCollection 2014.


Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations.

Pedersen SW, Pedersen SB, Anker L, Hultqvist G, Kristensen AS, Jemth P, Strømgaard K.

Nat Commun. 2014;5:3215. doi: 10.1038/ncomms4215.


Energetic pathway sampling in a protein interaction domain.

Hultqvist G, Haq SR, Punekar AS, Chi CN, Engström Å, Bach A, Strømgaard K, Selmer M, Gianni S, Jemth P.

Structure. 2013 Jul 2;21(7):1193-1202.


Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations.

Eildal JN, Hultqvist G, Balle T, Stuhr-Hansen N, Padrah S, Gianni S, Strømgaard K, Jemth P.

J Am Chem Soc. 2013 Sep 4;135(35):12998-3007. doi: 10.1021/ja402875h. Epub 2013 Jun 7.


Tolerance of protein folding to a circular permutation in a PDZ domain.

Hultqvist G, Punekar AS, Morrone A, Chi CN, Engström A, Selmer M, Gianni S, Jemth P.

PLoS One. 2012;7(11):e50055. doi: 10.1371/journal.pone.0050055. Epub 2012 Nov 21.


Evolution of the vertebrate paralemmin gene family: ancient origin of gene duplicates suggests distinct functions.

Hultqvist G, Ocampo Daza D, Larhammar D, Kilimann MW.

PLoS One. 2012;7(7):e41850. doi: 10.1371/journal.pone.0041850. Epub 2012 Jul 25.


An expanded view of the protein folding landscape of PDZ domains.

Hultqvist G, Pedersen SW, Chi CN, Strømgaard K, Gianni S, Jemth P.

Biochem Biophys Res Commun. 2012 May 11;421(3):550-3. doi: 10.1016/j.bbrc.2012.04.042. Epub 2012 Apr 13.


Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains.

Haq SR, Chi CN, Bach A, Dogan J, Engström Å, Hultqvist G, Karlsson OA, Lundström P, Montemiglio LC, Strømgaard K, Gianni S, Jemth P.

J Am Chem Soc. 2012 Jan 11;134(1):599-605. doi: 10.1021/ja209341w. Epub 2011 Dec 16.


Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site.

Limbach C, Laue MM, Wang X, Hu B, Thiede N, Hultqvist G, Kilimann MW.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):E392-401. doi: 10.1073/pnas.1101707108. Epub 2011 Jun 28.


A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

Wang X, Hu B, Zieba A, Neumann NG, Kasper-Sonnenberg M, Honsbein A, Hultqvist G, Conze T, Witt W, Limbach C, Geitmann M, Danielson H, Kolarow R, Niemann G, Lessmann V, Kilimann MW.

J Neurosci. 2009 Oct 7;29(40):12584-96. doi: 10.1523/JNEUROSCI.1255-09.2009.


Absorption of protruded disc tissue.


J Bone Joint Surg Am. 1950 Jul;32-A(3):557-60. No abstract available.


Förekomst av jätteväxt hos ungar till råttor med experimentell diabetes.


Nord Med. 1949 Feb 18;41(7):323. Undetermined Language. No abstract available.


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