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Items: 22


Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators.

Bates DO, Beazley-Long N, Benest AV, Ye X, Ved N, Hulse RP, Barratt S, Machado MJ, Donaldson LF, Harper SJ, Peiris-Pages M, Tortonese DJ, Oltean S, Foster RR.

Compr Physiol. 2018 Jun 18;8(3):955-979. doi: 10.1002/cphy.c170015.


Sensory neuronal sensitisation occurs through HMGB-1-RAGE and TRPV1 in high-glucose conditions.

Bestall SM, Hulse RP, Blackley Z, Swift M, Ved N, Paton K, Beazley-Long N, Bates DO, Donaldson LF.

J Cell Sci. 2018 Jul 26;131(14). pii: jcs215939. doi: 10.1242/jcs.215939.


Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain.

Ved N, Da Vitoria Lobo ME, Bestall SM, L Vidueira C, Beazley-Long N, Ballmer-Hofer K, Hirashima M, Bates DO, Donaldson LF, Hulse RP.

J Physiol. 2018 Aug;596(16):3675-3693. doi: 10.1113/JP275067. Epub 2018 Jul 11.


VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis.

Beazley-Long N, Moss CE, Ashby WR, Bestall SM, Almahasneh F, Durrant AM, Benest AV, Blackley Z, Ballmer-Hofer K, Hirashima M, Hulse RP, Bates DO, Donaldson LF.

Brain Behav Immun. 2018 Nov;74:49-67. doi: 10.1016/j.bbi.2018.03.012. Epub 2018 Mar 14.


Cancer Chemotherapy in Early Life Significantly Alters the Maturation of Pain Processing.

Hathway GJ, Murphy E, Lloyd J, Greenspon C, Hulse RP.

Neuroscience. 2018 Sep 1;387:214-229. doi: 10.1016/j.neuroscience.2017.11.032. Epub 2017 Dec 2.


Breast cancer induced nociceptor aberrant growth and collateral sensory axonal branching.

Austin M, Elliott L, Nicolaou N, Grabowska A, Hulse RP.

Oncotarget. 2017 Sep 1;8(44):76606-76621. doi: 10.18632/oncotarget.20609. eCollection 2017 Sep 29.


Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina.

Ved N, Hulse RP, Bestall SM, Donaldson LF, Bainbridge JW, Bates DO.

Clin Sci (Lond). 2017 Jun 1;131(12):1225-1243. doi: 10.1042/CS20170102. Epub 2017 Mar 24.


NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.

Di Stefano M, Loreto A, Orsomando G, Mori V, Zamporlini F, Hulse RP, Webster J, Donaldson LF, Gering M, Raffaelli N, Coleman MP, Gilley J, Conforti L.

Curr Biol. 2017 Mar 20;27(6):784-794. doi: 10.1016/j.cub.2017.01.070. Epub 2017 Mar 2.


Role of VEGF-A in chronic pain.

Hulse RP.

Oncotarget. 2017 Feb 14;8(7):10775-10776. doi: 10.18632/oncotarget.14615. No abstract available.


The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain.

Hulse RP, Drake RA, Bates DO, Donaldson LF.

Neurobiol Dis. 2016 Dec;96:186-200. doi: 10.1016/j.nbd.2016.09.009. Epub 2016 Sep 9.


Identification of mechano-sensitive C fibre sensitization and contribution to nerve injury-induced mechanical hyperalgesia.

Hulse RP.

Eur J Pain. 2016 Apr;20(4):615-25. doi: 10.1002/ejp.779. Epub 2015 Oct 2.


Cisplatin induced sensory neuropathy is prevented by vascular endothelial growth factor-A.

Vencappa S, Donaldson LF, Hulse RP.

Am J Transl Res. 2015 Jun 15;7(6):1032-44. eCollection 2015.


Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.

Hulse RP, Beazley-Long N, Ved N, Bestall SM, Riaz H, Singhal P, Ballmer Hofer K, Harper SJ, Bates DO, Donaldson LF.

Clin Sci (Lond). 2015 Oct 1;129(8):741-56. doi: 10.1042/CS20150124.


A novel method for delivering ramped cooling reveals rat behaviours at innocuous and noxious temperatures: A comparative study of human psychophysics and rat behaviour.

Dunham JP, Hulse RP, Donaldson LF.

J Neurosci Methods. 2015 Jul 15;249:29-40. doi: 10.1016/j.jneumeth.2015.03.032. Epub 2015 Apr 6.


Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy.

Oltean S, Qiu Y, Ferguson JK, Stevens M, Neal C, Russell A, Kaura A, Arkill KP, Harris K, Symonds C, Lacey K, Wijeyaratne L, Gammons M, Wylie E, Hulse RP, Alsop C, Cope G, Damodaran G, Betteridge KB, Ramnath R, Satchell SC, Foster RR, Ballmer-Hofer K, Donaldson LF, Barratt J, Baelde HJ, Harper SJ, Bates DO, Salmon AH.

J Am Soc Nephrol. 2015 Aug;26(8):1889-904. doi: 10.1681/ASN.2014040350. Epub 2014 Dec 26.


Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia.

Hulse RP, Beazley-Long N, Hua J, Kennedy H, Prager J, Bevan H, Qiu Y, Fernandes ES, Gammons MV, Ballmer-Hofer K, Gittenberger de Groot AC, Churchill AJ, Harper SJ, Brain SD, Bates DO, Donaldson LF.

Neurobiol Dis. 2014 Nov;71:245-59. doi: 10.1016/j.nbd.2014.08.012. Epub 2014 Aug 21.


The degree of acute descending control of spinal nociception in an area of primary hyperalgesia is dependent on the peripheral domain of afferent input.

Drake RA, Hulse RP, Lumb BM, Donaldson LF.

J Physiol. 2014 Aug 15;592(16):3611-24. doi: 10.1113/jphysiol.2013.266494. Epub 2014 May 30.


VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro.

Beazley-Long N, Hua J, Jehle T, Hulse RP, Dersch R, Lehrling C, Bevan H, Qiu Y, Lagrèze WA, Wynick D, Churchill AJ, Kehoe P, Harper SJ, Bates DO, Donaldson LF.

Am J Pathol. 2013 Sep;183(3):918-29. doi: 10.1016/j.ajpath.2013.05.031. Epub 2013 Jul 6.


Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.

Hughes SW, Hickey L, Hulse RP, Lumb BM, Pickering AE.

Pain. 2013 Sep;154(9):1680-90. doi: 10.1016/j.pain.2013.05.010. Epub 2013 May 14.


Differential roles of galanin on mechanical and cooling responses at the primary afferent nociceptor.

Hulse RP, Donaldson LF, Wynick D.

Mol Pain. 2012 Jun 6;8:41. doi: 10.1186/1744-8069-8-41.


Peripheral galanin receptor 2 as a target for the modulation of pain.

Hulse RP, Donaldson LF, Wynick D.

Pain Res Treat. 2012;2012:545386. doi: 10.1155/2012/545386. Epub 2012 Jan 24.


Activation of the galanin receptor 2 in the periphery reverses nerve injury-induced allodynia.

Hulse RP, Wynick D, Donaldson LF.

Mol Pain. 2011 Apr 16;7:26. doi: 10.1186/1744-8069-7-26.

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