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The self-reported needs of patients following subarachnoid hemorrhage (SAH).

Dulhanty LH, Hulme S, Vail A, Patel HC, Tyson SF.

Disabil Rehabil. 2019 Apr 18:1-7. doi: 10.1080/09638288.2019.1595748. [Epub ahead of print]


Drug sourcing and motivations among a sample of people involved in the supply of pharmaceutical drugs in Australia.

Hulme S, Hughes CE, Nielsen S.

Int J Drug Policy. 2019 Apr;66:38-47. doi: 10.1016/j.drugpo.2019.01.022. Epub 2019 Jan 25.


The connexin 30 A88V mutant reduces cochlear gap junction expression and confers long-term protection against hearing loss.

Kelly JJ, Abitbol JM, Hulme S, Press ER, Laird DW, Allman BL.

J Cell Sci. 2019 Jan 16;132(2). pii: jcs224097. doi: 10.1242/jcs.224097.


Inflammation and vascular permeability correlate with growth in sporadic vestibular schwannoma.

Lewis D, Roncaroli F, Agushi E, Mosses D, Williams R, Li KL, Zhu X, Hinz R, Atkinson R, Wadeson A, Hulme S, Mayers H, Stapleton E, Lloyd SKL, Freeman SR, Rutherford SA, Hammerbeck-Ward C, Evans DG, Pathmanaban O, Jackson A, King AT, Coope DJ.

Neuro Oncol. 2019 Feb 19;21(3):314-325. doi: 10.1093/neuonc/noy177.


Differential Immune Phenotypes in Human Monocytes Induced by Non-Host-Adapted Salmonella enterica Serovar Choleraesuis and Host-Adapted S. Typhimurium.

Ibrahim H, Askar B, Hulme S, Neilson P, Barrow P, Foster N.

Infect Immun. 2018 Sep 21;86(10). pii: e00509-18. doi: 10.1128/IAI.00509-18. Print 2018 Oct.


The source and diversion of pharmaceutical drugs for non-medical use: A systematic review and meta-analysis.

Hulme S, Bright D, Nielsen S.

Drug Alcohol Depend. 2018 May 1;186:242-256. doi: 10.1016/j.drugalcdep.2018.02.010. Epub 2018 Mar 27. Review.


SCIL-STROKE (Subcutaneous Interleukin-1 Receptor Antagonist in Ischemic Stroke): A Randomized Controlled Phase 2 Trial.

Smith CJ, Hulme S, Vail A, Heal C, Parry-Jones AR, Scarth S, Hopkins K, Hoadley M, Allan SM, Rothwell NJ, Hopkins SJ, Tyrrell PJ.

Stroke. 2018 May;49(5):1210-1216. doi: 10.1161/STROKEAHA.118.020750. Epub 2018 Mar 22.


PKC-Mediated Modulation of Astrocyte SNAT3 Glutamine Transporter Function at Synapses in Situ.

Dong W, Todd AC, Bröer A, Hulme SR, Bröer S, Billups B.

Int J Mol Sci. 2018 Mar 21;19(4). pii: E924. doi: 10.3390/ijms19040924.


Soft tissue infections from fish spike wounds: normal commensal bacteria are more common than marine pathogens.

Collins H, Lee KM, Cheng PT, Hulme S.

ANZ J Surg. 2018 Jan;88(1-2):E40-E44. doi: 10.1111/ans.13850. Epub 2017 Mar 20.


Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study.

Galea J, Ogungbenro K, Hulme S, Patel H, Scarth S, Hoadley M, Illingworth K, McMahon CJ, Tzerakis N, King AT, Vail A, Hopkins SJ, Rothwell N, Tyrrell P.

J Neurosurg. 2018 Feb;128(2):515-523. doi: 10.3171/2016.9.JNS16615. Epub 2017 Feb 24.


SNAT3-mediated glutamine transport in perisynaptic astrocytes in situ is regulated by intracellular sodium.

Todd AC, Marx MC, Hulme SR, Bröer S, Billups B.

Glia. 2017 Jun;65(6):900-916. doi: 10.1002/glia.23133. Epub 2017 Mar 8.


Development and feasibility testing of an oral hygiene intervention for stroke unit care.

Smith CJ, Horne M, McCracken G, Young D, Clements I, Hulme S, Ardron C, Hamdy S, Vail A, Walls A, Tyrrell PJ.

Gerodontology. 2017 Mar;34(1):110-120. doi: 10.1111/ger.12232. Epub 2016 May 16.


Temperature and Redox Effect on Mineral Colonization in Juan de Fuca Ridge Flank Subsurface Crustal Fluids.

Baquiran JP, Ramírez GA, Haddad AG, Toner BM, Hulme S, Wheat CG, Edwards KJ, Orcutt BN.

Front Microbiol. 2016 Mar 31;7:396. doi: 10.3389/fmicb.2016.00396. eCollection 2016.


A distinct and active bacterial community in cold oxygenated fluids circulating beneath the western flank of the Mid-Atlantic ridge.

Meyer JL, Jaekel U, Tully BJ, Glazer BT, Wheat CG, Lin HT, Hsieh CC, Cowen JP, Hulme SM, Girguis PR, Huber JA.

Sci Rep. 2016 Mar 3;6:22541. doi: 10.1038/srep22541.


Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist.

Ogungbenro K, Hulme S, Rothwell N, Hopkins S, Tyrrell P, Galea J.

J Pharmacokinet Pharmacodyn. 2016 Feb;43(1):1-12.


Distribution and enrichment of trace metals in marine sediments from the Eastern Equatorial Atlantic, off the Coast of Ghana in the Gulf of Guinea.

Mahu E, Nyarko E, Hulme S, Coale KH.

Mar Pollut Bull. 2015 Sep 15;98(1-2):301-7. doi: 10.1016/j.marpolbul.2015.06.044. Epub 2015 Jun 29.


L-type calcium channel-dependent inhibitory plasticity in the thalamus.

Hulme SR, Connelly WM.

J Neurophysiol. 2014 Nov 1;112(9):2037-9. doi: 10.1152/jn.00918.2013. Epub 2014 Mar 12. Review.


The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial.

Singh N, Hopkins SJ, Hulme S, Galea JP, Hoadley M, Vail A, Hutchinson PJ, Grainger S, Rothwell NJ, King AT, Tyrrell PJ.

J Neuroinflammation. 2014 Jan 3;11:1. doi: 10.1186/1742-2094-11-1.


Mechanisms of heterosynaptic metaplasticity.

Hulme SR, Jones OD, Raymond CR, Sah P, Abraham WC.

Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130148. doi: 10.1098/rstb.2013.0148. Print 2014 Jan 5. Review.


Oxygen consumption rates in subseafloor basaltic crust derived from a reaction transport model.

Orcutt BN, Wheat CG, Rouxel O, Hulme S, Edwards KJ, Bach W.

Nat Commun. 2013;4:2539. doi: 10.1038/ncomms3539.


Purinergic receptor- and gap junction-mediated intercellular signalling as a mechanism of heterosynaptic metaplasticity.

Jones OD, Hulme SR, Abraham WC.

Neurobiol Learn Mem. 2013 Oct;105:31-9. doi: 10.1016/j.nlm.2013.05.010. Epub 2013 Jun 5.


Emerging roles of metaplasticity in behaviour and disease.

Hulme SR, Jones OD, Abraham WC.

Trends Neurosci. 2013 Jun;36(6):353-62. doi: 10.1016/j.tins.2013.03.007. Epub 2013 Apr 17. Review.


Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection.

Hopkins SJ, McMahon CJ, Singh N, Galea J, Hoadley M, Scarth S, Patel H, Vail A, Hulme S, Rothwell NJ, King AT, Tyrrell PJ.

J Neuroinflammation. 2012 Nov 23;9:255. doi: 10.1186/1742-2094-9-255.


Inhibited Production of iNOS by Murine J774 Macrophages Occurs via a phoP-Regulated Differential Expression of NFκB and AP-1.

Hulme SD, Barrow PA, Foster N.

Interdiscip Perspect Infect Dis. 2012;2012:483170. doi: 10.1155/2012/483170. Epub 2012 Jul 17.


The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans.

Pinan-Lucarre B, Gabel CV, Reina CP, Hulme SE, Shevkoplyas SS, Slone RD, Xue J, Qiao Y, Weisberg S, Roodhouse K, Sun L, Whitesides GM, Samuel A, Driscoll M.

PLoS Biol. 2012;10(5):e1001331. doi: 10.1371/journal.pbio.1001331. Epub 2012 May 22.


Calcium-dependent but action potential-independent BCM-like metaplasticity in the hippocampus.

Hulme SR, Jones OD, Ireland DR, Abraham WC.

J Neurosci. 2012 May 16;32(20):6785-94. doi: 10.1523/JNEUROSCI.0634-12.2012.


A microfluidic device for whole-animal drug screening using electrophysiological measures in the nematode C. elegans.

Lockery SR, Hulme SE, Roberts WM, Robinson KJ, Laromaine A, Lindsay TH, Whitesides GM, Weeks JC.

Lab Chip. 2012 Jun 21;12(12):2211-20. doi: 10.1039/c2lc00001f. Epub 2012 May 15.


Photosynthetic pathway and ecological adaptation explain stomatal trait diversity amongst grasses.

Taylor SH, Franks PJ, Hulme SP, Spriggs E, Christin PA, Edwards EJ, Woodward FI, Osborne CP.

New Phytol. 2012 Jan;193(2):387-96. doi: 10.1111/j.1469-8137.2011.03935.x. Epub 2011 Nov 1.


External ventricular drain infection: improved technique can reduce infection rates.

Kitchen WJ, Singh N, Hulme S, Galea J, Patel HC, King AT.

Br J Neurosurg. 2011 Oct;25(5):632-5. doi: 10.3109/02688697.2011.578770.


Salmonella enterica serovar typhimurium colonizing the lumen of the chicken intestine grows slowly and upregulates a unique set of virulence and metabolism genes.

Harvey PC, Watson M, Hulme S, Jones MA, Lovell M, Berchieri A Jr, Young J, Bumstead N, Barrow P.

Infect Immun. 2011 Oct;79(10):4105-21. doi: 10.1128/IAI.01390-10. Epub 2011 Jul 18.


Calcium/calmodulin-dependent protein kinase II mediates group I metabotropic glutamate receptor-dependent protein synthesis and long-term depression in rat hippocampus.

Mockett BG, Guévremont D, Wutte M, Hulme SR, Williams JM, Abraham WC.

J Neurosci. 2011 May 18;31(20):7380-91. doi: 10.1523/JNEUROSCI.6656-10.2011.


Does inflammation predispose to recurrent vascular events after recent transient ischaemic attack and minor stroke? The North West of England transient ischaemic attack and minor stroke (NORTHSTAR) study.

Selvarajah JR, Smith CJ, Hulme S, Georgiou R, Sherrington C, Staniland J, Illingworth KJ, Jury F, Payton A, Ollier WE, Vail A, Rothwell NJ, Hopkins SJ, Tyrrell PJ.

Int J Stroke. 2011 Jun;6(3):187-94. doi: 10.1111/j.1747-4949.2010.00561.x. Epub 2011 Jan 13.


Chemistry and the worm: Caenorhabditis elegans as a platform for integrating chemical and biological research.

Hulme SE, Whitesides GM.

Angew Chem Int Ed Engl. 2011 May 16;50(21):4774-807. doi: 10.1002/anie.201005461. Epub 2011 Apr 15. Review.


Total donor ischemic time: relationship to early hemodynamics and intensive care morbidity in pediatric cardiac transplant recipients.

Rodrigues W, Carr M, Ridout D, Carter K, Hulme SL, Simmonds J, Elliott M, Hoskote A, Burch M, Brown KL.

Pediatr Crit Care Med. 2011 Nov;12(6):660-6. doi: 10.1097/PCC.0b013e3182192a84.


Brain inflammation is induced by co-morbidities and risk factors for stroke.

Drake C, Boutin H, Jones MS, Denes A, McColl BW, Selvarajah JR, Hulme S, Georgiou RF, Hinz R, Gerhard A, Vail A, Prenant C, Julyan P, Maroy R, Brown G, Smigova A, Herholz K, Kassiou M, Crossman D, Francis S, Proctor SD, Russell JC, Hopkins SJ, Tyrrell PJ, Rothwell NJ, Allan SM.

Brain Behav Immun. 2011 Aug;25(6):1113-22. doi: 10.1016/j.bbi.2011.02.008. Epub 2011 Feb 26.


Partitioning the components of relative growth rate: how important is plant size variation?

Rees M, Osborne CP, Woodward FI, Hulme SP, Turnbull LA, Taylor SH.

Am Nat. 2010 Dec;176(6):E152-61. doi: 10.1086/657037. Epub 2010 Oct 15.


A Portable CT Scanner in the Pediatric Intensive Care Unit Decreases Transfer-Associated Adverse Events and Staff Disruption.

Agrawal S, Hulme SL, Hayward R, Brierley J.

Eur J Trauma Emerg Surg. 2010 Aug;36(4):346-52. doi: 10.1007/s00068-009-9127-8. Epub 2009 Nov 2.


Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study.

Galea J, Ogungbenro K, Hulme S, Greenhalgh A, Aarons L, Scarth S, Hutchinson P, Grainger S, King A, Hopkins SJ, Rothwell N, Tyrrell P.

J Cereb Blood Flow Metab. 2011 Feb;31(2):439-47. doi: 10.1038/jcbfm.2010.103. Epub 2010 Jul 14.


Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans.

Hulme SE, Shevkoplyas SS, McGuigan AP, Apfeld J, Fontana W, Whitesides GM.

Lab Chip. 2010 Mar 7;10(5):589-97. doi: 10.1039/b919265d. Epub 2009 Dec 18.


Ecophysiological traits in C3 and C4 grasses: a phylogenetically controlled screening experiment.

Taylor SH, Hulme SP, Rees M, Ripley BS, Woodward FI, Osborne CP.

New Phytol. 2010 Feb;185(3):780-91. doi: 10.1111/j.1469-8137.2009.03102.x. Epub 2009 Dec 1.


Incorporation of prefabricated screw, pneumatic, and solenoid valves into microfluidic devices.

Hulme SE, Shevkoplyas SS, Whitesides GM.

Lab Chip. 2009 Jan 7;9(1):79-86. doi: 10.1039/b809673b. Epub 2008 Oct 21.


Analysis of the role of 13 major fimbrial subunits in colonisation of the chicken intestines by Salmonella enterica serovar Enteritidis reveals a role for a novel locus.

Clayton DJ, Bowen AJ, Hulme SD, Buckley AM, Deacon VL, Thomson NR, Barrow PA, Morgan E, Jones MA, Watson M, Stevens MP.

BMC Microbiol. 2008 Dec 18;8:228. doi: 10.1186/1471-2180-8-228.


Potential surrogate markers of cerebral microvascular angiopathy in asymptomatic subjects at risk of stroke.

Selvarajah J, Scott M, Stivaros S, Hulme S, Georgiou R, Rothwell N, Tyrrell P, Jackson A.

Eur Radiol. 2009 Apr;19(4):1011-8. doi: 10.1007/s00330-008-1202-8. Epub 2008 Nov 6.


Metaplasticity: new insights through electrophysiological investigations.

Mockett BG, Hulme SR.

J Integr Neurosci. 2008 Jun;7(2):315-36. Review.


Microfluidics: streamlining discovery in worm biology.

Hulme SE, Shevkoplyas SS, Samuel A.

Nat Methods. 2008 Jul;5(7):589-90. doi: 10.1038/nmeth0708-589. No abstract available.


Prognosis in patients with transient ischaemic attack (TIA) and minor stroke attending TIA services in the North West of England: the NORTHSTAR Study.

Selvarajah JR, Smith CJ, Hulme S, Georgiou RF, Vail A, Tyrrell PJ; NORTHSTAR Collaborators.

J Neurol Neurosurg Psychiatry. 2008 Jan;79(1):38-43. Epub 2007 Nov 22.


A microfabricated array of clamps for immobilizing and imaging C. elegans.

Hulme SE, Shevkoplyas SS, Apfeld J, Fontana W, Whitesides GM.

Lab Chip. 2007 Nov;7(11):1515-23. Epub 2007 Aug 16.


Stewart-Treves syndrome in a congenitally lymphedematous upper limb.

Hulme SA, Bialostocki A, Hardy SL, Tills MR.

Plast Reconstr Surg. 2007 Mar;119(3):1140-1. No abstract available.


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