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Measuring and optimising the efficiency of community hospital inpatient care for older people: the MoCHA mixed-methods study.

Young J, Hulme C, Smith A, Buckell J, Godfrey M, Holditch C, Grantham J, Tucker H, Enderby P, Gladman J, Teale E, Thiebaud JC.

Southampton (UK): NIHR Journals Library; 2020 Jan.


Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.

Vanden Eynde JJ, Mangoni AA, Rautio J, Leprince J, Azuma YT, García-Sosa AT, Hulme C, Jampilek J, Karaman R, Li W, Gomes PAC, Hadjipavlou-Litina D, Capasso R, Geronikaki A, Cerchia L, Sabatier JM, Ragno R, Tuccinardi T, Trabocchi A, Winum JY, Luque FJ, Prokai-Tatrai K, Spetea M, Gütschow M, Kosalec I, Guillou C, Vasconcelos MH, Kokotos G, Rastelli G, de Sousa ME, Manera C, Gemma S, Mangani S, Siciliano C, Galdiero S, Liu H, Scott PJH, de Los Ríos C, Agrofoglio LA, Collina S, Guedes RC, Muñoz-Torrero D.

Molecules. 2019 Dec 28;25(1). pii: E119. doi: 10.3390/molecules25010119.


Liaison psychiatry-measurement and evaluation of service types, referral patterns and outcomes (LP-MAESTRO): a protocol.

Smith C, Hewison J, West RM, Guthrie E, Trigwell P, Crawford MJ, Czoski Murray CJ, Fossey M, Hulme C, Tubeuf S, House A.

BMJ Open. 2019 Nov 24;9(11):e032179. doi: 10.1136/bmjopen-2019-032179.


Pressure Relieving Support Surfaces for Pressure Ulcer Prevention (PRESSURE 2): Clinical and Health Economic Results of a Randomised Controlled Trial.

Nixon J, Smith IL, Brown S, McGinnis E, Vargas-Palacios A, Nelson EA, Coleman S, Collier H, Fernandez C, Gilberts R, Henderson V, Muir D, Stubbs N, Walker K, Wilson L, Hulme C.

EClinicalMedicine. 2019 Sep 3;14:42-52. doi: 10.1016/j.eclinm.2019.07.018. eCollection 2019 Sep.


Prophylactic levofloxacin to prevent infections in newly diagnosed symptomatic myeloma: the TEAMM RCT.

Drayson MT, Bowcock S, Planche T, Iqbal G, Pratt G, Yong K, Wood J, Raynes K, Higgins H, Dawkins B, Meads D, Hulme CT, Whittaker AC, Hawkey P, Low E, Dunn JA.

Health Technol Assess. 2019 Nov;23(62):1-94. doi: 10.3310/hta23620.


Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial.

Drayson MT, Bowcock S, Planche T, Iqbal G, Pratt G, Yong K, Wood J, Raynes K, Higgins H, Dawkins B, Meads D, Hulme CT, Monahan I, Karunanithi K, Dignum H, Belsham E, Neilson J, Harrison B, Lokare A, Campbell G, Hamblin M, Hawkey P, Whittaker AC, Low E, Dunn JA; TEAMM Trial Management Group and Trial Investigators.

Lancet Oncol. 2019 Dec;20(12):1760-1772. doi: 10.1016/S1470-2045(19)30506-6. Epub 2019 Oct 23.


Dyslexia and Developmental Language Disorder: comorbid disorders with distinct effects on reading comprehension.

Snowling MJ, Hayiou-Thomas ME, Nash HM, Hulme C.

J Child Psychol Psychiatry. 2019 Oct 20. doi: 10.1111/jcpp.13140. [Epub ahead of print]


Remuneration of primary dental care in England: a qualitative framework analysis of perspectives of a new service delivery model incorporating incentives for improved access, quality and health outcomes.

Robinson PG, Douglas GVA, Gibson BJ, Godson J, Vinall-Collier K, Pavitt S, Hulme C.

BMJ Open. 2019 Oct 3;9(10):e031886. doi: 10.1136/bmjopen-2019-031886.


The effect of high glucose on lipid metabolism in the human placenta.

Hulme CH, Nicolaou A, Murphy SA, Heazell AEP, Myers JE, Westwood M.

Sci Rep. 2019 Oct 1;9(1):14114. doi: 10.1038/s41598-019-50626-x.


Comparing alternating pressure mattresses and high-specification foam mattresses to prevent pressure ulcers in high-risk patients: the PRESSURE 2 RCT.

Nixon J, Brown S, Smith IL, McGinnis E, Vargas-Palacios A, Nelson EA, Brown J, Coleman S, Collier H, Fernandez C, Gilberts R, Henderson V, McCabe C, Muir D, Rutherford C, Stubbs N, Thorpe B, Wallner K, Walker K, Wilson L, Hulme C.

Health Technol Assess. 2019 Sep;23(52):1-176. doi: 10.3310/hta23520.


Robotic-assisted surgery compared with laparoscopic resection surgery for rectal cancer: the ROLARR RCT.

Jayne D, Pigazzi A, Marshall H, Croft J, Corrigan N, Copeland J, Quirke P, West N, Edlin R, Hulme C, Brown J.

Southampton (UK): NIHR Journals Library; 2019 Sep.


Toward a Framework for Outcome-Based Analytical Performance Specifications: A Methodology Review of Indirect Methods for Evaluating the Impact of Measurement Uncertainty on Clinical Outcomes.

Smith AF, Shinkins B, Hall PS, Hulme CT, Messenger MP.

Clin Chem. 2019 Nov;65(11):1363-1374. doi: 10.1373/clinchem.2018.300954. Epub 2019 Aug 23. Review.


Computerized Speechreading Training for Deaf Children: A Randomized Controlled Trial.

Pimperton H, Kyle F, Hulme C, Harris M, Beedie I, Ralph-Lewis A, Worster E, Rees R, Donlan C, MacSweeney M.

J Speech Lang Hear Res. 2019 Aug 15;62(8):2882-2894. doi: 10.1044/2019_JSLHR-H-19-0073. Epub 2019 Jul 23.


A Preliminary Cohort Study Assessing Routine Blood Analyte Levels and Neurological Outcome after Spinal Cord Injury.

Brown SJ, Harrington GMB, Hulme CH, Morris R, Bennett A, Tsang WH, Osman A, Chowdhury J, Kumar N, Wright KT.

J Neurotrauma. 2020 Feb 1;37(3):466-480. doi: 10.1089/neu.2019.6495. Epub 2019 Aug 6.


Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5.

Mangoni AA, Eynde JJV, Jampilek J, Hadjipavlou-Litina D, Liu H, Reynisson J, Sousa ME, Gomes PAC, Prokai-Tatrai K, Tuccinardi T, Sabatier JM, Luque FJ, Rautio J, Karaman R, Vasconcelos MH, Gemma S, Galdiero S, Hulme C, Collina S, Gütschow M, Kokotos G, Siciliano C, Capasso R, Agrofoglio LA, Ragno R, Muñoz-Torrero D.

Molecules. 2019 Jun 30;24(13). pii: E2415. doi: 10.3390/molecules24132415.


Stage 2 Registered Report: There is no appreciable relationship between strength of hand preference and language ability in 6- to 7-year-old children.

Pritchard VE, Malone SA, Burgoyne K, Heron-Delaney M, Bishop DVM, Hulme C.

Wellcome Open Res. 2019 May 13;4:81. doi: 10.12688/wellcomeopenres.15254.1. eCollection 2019.


Chronic Dyrk1 Inhibition Delays the Onset of AD-Like Pathology in 3xTg-AD Mice.

Velazquez R, Meechoovet B, Ow A, Foley C, Shaw A, Smith B, Oddo S, Hulme C, Dunckley T.

Mol Neurobiol. 2019 Dec;56(12):8364-8375. doi: 10.1007/s12035-019-01684-9. Epub 2019 Jun 25.


Data on numerosity discrimination, inhibition and arithmetic during the early school years.

Malone SA, Pritchard VE, Heron-Delaney M, Burgoyne K, Lervåg A, Hulme C.

Data Brief. 2019 May 25;25:104062. doi: 10.1016/j.dib.2019.104062. eCollection 2019 Aug.


6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial.

Earl HM, Hiller L, Vallier AL, Loi S, McAdam K, Hughes-Davies L, Harnett AN, Ah-See ML, Simcock R, Rea D, Raj S, Woodings P, Harries M, Howe D, Raynes K, Higgins HB, Wilcox M, Plummer C, Mansi J, Gounaris I, Mahler-Araujo B, Provenzano E, Chhabra A, Abraham JE, Caldas C, Hall PS, McCabe C, Hulme C, Miles D, Wardley AM, Cameron DA, Dunn JA; PERSEPHONE Steering Committee and Trial Investigators.

Lancet. 2019 Jun 29;393(10191):2599-2612. doi: 10.1016/S0140-6736(19)30650-6. Epub 2019 Jun 6.


Mind the (Inferential) Gap: Giles et al. (2018) Provide No Convincing Evidence for a Causal Relationship Between Interceptive-Timing Ability and Arithmetic Attainment.

Hulme C.

Psychol Sci. 2019 Jul;30(7):1097-1098. doi: 10.1177/0956797619834513. Epub 2019 May 23. No abstract available.


Anal fistula plug versus surgeon's preference for surgery for trans-sphincteric anal fistula: the FIAT RCT.

Jayne DG, Scholefield J, Tolan D, Gray R, Edlin R, Hulme CT, Sutton AJ, Handley K, Hewitt CA, Kaur M, Magill L.

Health Technol Assess. 2019 May;23(21):1-76. doi: 10.3310/hta23210.


Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases.

Wang J, Wright KT, Perry J, Tins B, Hopkins T, Hulme C, McCarthy HS, Brown A, Richardson JB.

Cell Transplant. 2019 Jul;28(7):924-931. doi: 10.1177/0963689719845328. Epub 2019 May 8.


Procedural and declarative learning in dyslexia.

West G, Clayton FJ, Shanks DR, Hulme C.

Dyslexia. 2019 Aug;25(3):246-255. doi: 10.1002/dys.1615. Epub 2019 Apr 23.


The relationship between numerosity discrimination and arithmetic skill reflects the approximate number system and cannot be explained by inhibitory control.

Malone SA, Pritchard VE, Heron-Delaney M, Burgoyne K, Lervåg A, Hulme C.

J Exp Child Psychol. 2019 Aug;184:220-231. doi: 10.1016/j.jecp.2019.02.009. Epub 2019 Mar 29.


Improving storytelling and vocabulary in secondary school students with language disorder: a randomized controlled trial.

Joffe VL, Rixon L, Hulme C.

Int J Lang Commun Disord. 2019 Jul;54(4):656-672. doi: 10.1111/1460-6984.12471. Epub 2019 Mar 29.


Stage 1 Registered Report: The relationship between handedness and language ability in children.

Pritchard VE, Malone SA, Burgoyne K, Heron-Delaney M, Bishop DVM, Hulme C.

Wellcome Open Res. 2019 Feb 14;4:30. doi: 10.12688/wellcomeopenres.15077.1. eCollection 2019.


A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells.

Mennan C, Garcia J, Roberts S, Hulme C, Wright K.

Stem Cell Res Ther. 2019 Mar 18;10(1):99. doi: 10.1186/s13287-019-1202-4.


Cost-Effectiveness of Pain Management Strategies in Advanced Cancer.

Meads DM, O'Dwyer JL, Hulme CT, Lopez RR, Bennett MI.

Int J Technol Assess Health Care. 2019 Jan;35(2):141-149. doi: 10.1017/S0266462319000114. Epub 2019 Mar 15.


Learning correspondences between magnitudes, symbols and words: Evidence for a triple code model of arithmetic development.

Malone SA, Heron-Delaney M, Burgoyne K, Hulme C.

Cognition. 2019 Jun;187:1-9. doi: 10.1016/j.cognition.2018.11.016. Epub 2019 Feb 20.


The procedural deficit hypothesis of language learning disorders: We still see some serious problems.

West G, Vadillo MA, Shanks DR, Hulme C.

Dev Sci. 2019 Jul;22(4):e12813. doi: 10.1111/desc.12813. Epub 2019 Mar 4. No abstract available.


Developmental Outcomes for Children at High Risk of Dyslexia and Children With Developmental Language Disorder.

Snowling MJ, Nash HM, Gooch DC, Hayiou-Thomas ME, Hulme C; Wellcome Language and Reading Project Team.

Child Dev. 2019 Sep;90(5):e548-e564. doi: 10.1111/cdev.13216. Epub 2019 Jan 24.


Long-term issues and supportive care needs of adolescent and young adult childhood brain tumour survivors and their caregivers: A systematic review.

Nicklin E, Velikova G, Hulme C, Rodriguez Lopez R, Glaser A, Kwok-Williams M, Boele F.

Psychooncology. 2019 Mar;28(3):477-487. doi: 10.1002/pon.4989. Epub 2019 Feb 1. Review.


Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4.

Mangoni AA, Guillou C, Vanden Eynde JJ, Hulme C, Jampilek J, Li W, Prokai-Tatrai K, Rautio J, Collina S, Tuccinardi T, Sousa ME, Sabatier JM, Galdiero S, Karaman R, Kokotos G, Torri G, Luque FJ, Vasconcelos MH, Hadjipavlou-Litina D, Siciliano C, Gütschow M, Ragno R, Gomes PAC, Agrofoglio LA, Muñoz-Torrero D.

Molecules. 2018 Dec 31;24(1). pii: E130. doi: 10.3390/molecules24010130.


The weight-specific adolescent instrument for economic evaluation (WAItE): psychometric evaluation using a Rasch model approach.

Oluboyede Y, Smith AB, Hill A, Hulme C.

Qual Life Res. 2019 Apr;28(4):969-977. doi: 10.1007/s11136-018-2074-2. Epub 2018 Dec 5.


The feasibility of using the EQ-5D-3L with adults with mild to moderate learning disabilities within a randomized control trial: a qualitative evaluation.

Russell AM, O'Dwyer JL, Bryant LD, House AO, Birtwistle JC, Meer S, Wright-Hughes A, Walwyn REA, Graham E, Farrin AJ, Hulme CT.

Pilot Feasibility Stud. 2018 Oct 29;4:164. doi: 10.1186/s40814-018-0357-6. eCollection 2018.


A programme theory for liaison mental health services in England.

House A, Guthrie E, Walker A, Hewsion J, Trigwell P, Brennan C, Crawford M, Murray CC, Fossey M, Hulme C, Martin A, Quirk A, Tubeuf S.

BMC Health Serv Res. 2018 Sep 27;18(1):742. doi: 10.1186/s12913-018-3539-2.


PATCH: posture and mobility training for care staff versus usual care in care homes: study protocol for a randomised controlled trial.

Graham L, Cicero R, Clarke D, Cundill B, Ellwood A, Farrin A, Fisher J, Goodwin M, Hawkins R, Hull K, Hulme C, Trépel D, Williams R, Forster A.

Trials. 2018 Sep 24;19(1):521. doi: 10.1186/s13063-018-2863-5.


Longitudinal relationships between speech perception, phonological skills and reading in children at high-risk of dyslexia.

Snowling MJ, Lervåg A, Nash HM, Hulme C.

Dev Sci. 2019 Jan;22(1):e12723. doi: 10.1111/desc.12723. Epub 2018 Sep 12.


Learning to read in Chinese: Evidence for reciprocal relationships between word reading and oral language skills.

Hulme C, Zhou L, Tong X, Lervåg A, Burgoyne K.

Dev Sci. 2019 Jan;22(1):e12745. doi: 10.1111/desc.12745. Epub 2018 Oct 2.


Cost-effectiveness analysis of a multi-dimensional intervention to reduce inappropriate antibiotic prescribing for children with upper respiratory tract infections in China.

Zhang Z, Dawkins B, Hicks JP, Walley JD, Hulme C, Elsey H, Deng S, Lin M, Zeng J, Wei X.

Trop Med Int Health. 2018 Oct;23(10):1092-1100. doi: 10.1111/tmi.13132. Epub 2018 Aug 24.


Methods for the evaluation of biomarkers in patients with kidney and liver diseases: multicentre research programme including ELUCIDATE RCT.

Selby PJ, Banks RE, Gregory W, Hewison J, Rosenberg W, Altman DG, Deeks JJ, McCabe C, Parkes J, Sturgeon C, Thompson D, Twiddy M, Bestall J, Bedlington J, Hale T, Dinnes J, Jones M, Lewington A, Messenger MP, Napp V, Sitch A, Tanwar S, Vasudev NS, Baxter P, Bell S, Cairns DA, Calder N, Corrigan N, Del Galdo F, Heudtlass P, Hornigold N, Hulme C, Hutchinson M, Lippiatt C, Livingstone T, Longo R, Potton M, Roberts S, Sim S, Trainor S, Welberry Smith M, Neuberger J, Thorburn D, Richardson P, Christie J, Sheerin N, McKane W, Gibbs P, Edwards A, Soomro N, Adeyoju A, Stewart GD, Hrouda D.

Southampton (UK): NIHR Journals Library; 2018 Jun.


eRAPID electronic patient self-Reporting of Adverse-events: Patient Information and aDvice: a pilot study protocol in pelvic radiotherapy.

Holch P, Pini S, Henry AM, Davidson S, Routledge J, Brown J, Absolom K, Gilbert A, Franks K, Hulme C, Morris C, Velikova G; eRAPID radiotherapy work group.

Pilot Feasibility Stud. 2018 Jun 5;4:110. doi: 10.1186/s40814-018-0304-6. eCollection 2018.


A multi-centre investigation of delivering national guidelines on exercise training for men with advanced prostate cancer undergoing androgen deprivation therapy in the UK NHS.

Bourke L, Turner R, Greasley R, Sutton E, Steed L, Smith D, Brown J, Kelly B, Hulme C, Greenfield D, Persad R, Farrin A, Hewison J, Rosario DJ; STAMINA investigators.

PLoS One. 2018 Jul 5;13(7):e0197606. doi: 10.1371/journal.pone.0197606. eCollection 2018.


Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3.

Mangoni AA, Tuccinardi T, Collina S, Vanden Eynde JJ, Muñoz-Torrero D, Karaman R, Siciliano C, de Sousa ME, Prokai-Tatrai K, Rautio J, Guillou C, Gütschow M, Galdiero S, Liu H, Agrofoglio LA, Sabatier JM, Hulme C, Kokotos G, You Q, Gomes PAC.

Molecules. 2018 Jun 30;23(7). pii: E1596. doi: 10.3390/molecules23071596. No abstract available.


Eye Movements During Visual Speech Perception in Deaf and Hearing Children.

Worster E, Pimperton H, Ralph-Lewis A, Monroy L, Hulme C, MacSweeney M.

Lang Learn. 2018 Jun;68(Suppl Suppl 1):159-179. doi: 10.1111/lang.12264. Epub 2017 Sep 26.


The Home Literacy Environment Is a Correlate, but Perhaps Not a Cause, of Variations in Children's Language and Literacy Development.

Puglisi ML, Hulme C, Hamilton LG, Snowling MJ.

Sci Stud Read. 2017 Jul 25;21(6):498-514. doi: 10.1080/10888438.2017.1346660. eCollection 2017.


Alternative tumour necrosis factor inhibitors (TNFi) or abatacept or rituximab following failure of initial TNFi in rheumatoid arthritis: the SWITCH RCT.

Brown S, Everett CC, Naraghi K, Davies C, Dawkins B, Hulme C, McCabe C, Pavitt S, Emery P, Sharples L, Buch MH.

Health Technol Assess. 2018 Jun;22(34):1-280. doi: 10.3310/hta22340.


An intervention to support stroke survivors and their carers in the longer term (LoTS2Care): study protocol for a cluster randomised controlled feasibility trial.

Forster A, Hartley S, Barnard L, Ozer S, Hardicre N, Crocker T, Fletcher M, Moreau L, Atkinson R, Hulme C, Holloway I, Schmitt L, House A, Hewison J, Richardson G, Farrin A; LoTS2Care Programme Management Group.

Trials. 2018 Jun 11;19(1):317. doi: 10.1186/s13063-018-2669-5.


Effectiveness of a small-group vocabulary intervention programme: evidence from a regression discontinuity design.

Dyson H, Solity J, Best W, Hulme C.

Int J Lang Commun Disord. 2018 Sep;53(5):947-958. doi: 10.1111/1460-6984.12404. Epub 2018 Jun 7.


Managing with Learning Disability and Diabetes: OK-Diabetes - a case-finding study and feasibility randomised controlled trial.

House A, Bryant L, Russell AM, Wright-Hughes A, Graham L, Walwyn R, Wright JM, Hulme C, O'Dwyer JL, Latchford G, Meer S, Birtwistle JC, Stansfield A, Ajjan R, Farrin A.

Health Technol Assess. 2018 May;22(26):1-328. doi: 10.3310/hta22260.

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