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Utilizing Stimulated Raman Scattering Microscopy To Study Intracellular Distribution of Label-Free Ponatinib in Live Cells.

Sepp K, Lee M, Bluntzer MTJ, Helgason GV, Hulme AN, Brunton VG.

J Med Chem. 2019 Dec 27. doi: 10.1021/acs.jmedchem.9b01546. [Epub ahead of print]


Computational and theoretical approaches for mechanistic understanding: general discussion.

Bauer M, Cadge J, Davies D, Durand DJ, Eisenstein O, Ess D, Fey N, Gallarati S, George M, Hamilton A, Harvey J, Hintermair U, Hulme AN, Ishii Y, Jensen VR, Lloyd-Jones G, Love J, Lynam J, Macgregor S, Marder TB, Meijer EJ, Morgan P, Morris RH, Mwansa J, Odom A, Perutz R, Reiher M, Schafer L, Slattery J, Young T.

Faraday Discuss. 2019 Dec 2;220(0):464-488. doi: 10.1039/C9FD90073J. No abstract available.


Physical methods for mechanistic understanding: general discussion.

Aoki Y, Bauer M, Braun T, Cadge J, Davies D, Durand DJ, Eisenstein O, Ess D, Fairlamb I, Fey N, Gallarati S, George M, Greaves M, Halse M, Hamilton A, Harvey J, Haynes A, Hintermair U, Hulme AN, Ishii Y, Jakoobi M, Jensen VR, Kennepohl P, Kuwata S, Lei A, Lloyd-Jones G, Love J, Lovelock K, Lynam J, Macgregor S, Marder TB, Meijer EJ, Morgan P, Morris RH, Mwansa J, Nelson D, Odom A, Perutz R, Reiher M, Renny J, Roithová J, Schafer L, Schilter D, Scott S, Slattery J, Walton J, Wilden JD, Wong CY, Yaman T, Young T.

Faraday Discuss. 2019 Dec 2;220(0):144-178. doi: 10.1039/C9FD90070E. No abstract available.


Mechanistic insight into organic and industrial transformations: general discussion.

Aoki Y, Bauer M, Braun T, Cadge JA, Clarke GE, Durand DJ, Eisenstein O, Gallarati S, Greaves M, Harvey J, Haynes A, Hintermair U, Hulme AN, Ishii Y, Jakoobi M, Jensen VR, Kennepohl P, Kuwata S, Lei A, Lloyd-Jones G, Love J, Lynam J, Macgregor S, Morris RH, Nelson D, Odom A, Perutz R, Reiher M, Renny J, Roithova J, Schafer L, Scott S, Seavill PW, Slattery J, Takao T, Walton J, Wilden JD, Wong CY, Young T.

Faraday Discuss. 2019 Dec 2;220(0):282-316. doi: 10.1039/C9FD90072A. No abstract available.


Radical systems thinking and the future role of computational modelling in ergonomics: an exploration of agent-based modelling.

Holman M, Walker G, Lansdown T, Hulme A.

Ergonomics. 2019 Dec 2:1-18. doi: 10.1080/00140139.2019.1694173. [Epub ahead of print]


Combining SPR with atomic-force microscopy enables single-molecule insights into activation and suppression of the complement cascade.

Makou E, Bailey RG, Johnston H, Parkin JD, Hulme AN, Hähner G, Barlow PN.

J Biol Chem. 2019 Dec 27;294(52):20148-20163. doi: 10.1074/jbc.RA119.010913. Epub 2019 Nov 12.


The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.

Liu PY, Tee AE, Milazzo G, Hannan KM, Maag J, Mondal S, Atmadibrata B, Bartonicek N, Peng H, Ho N, Mayoh C, Ciaccio R, Sun Y, Henderson MJ, Gao J, Everaert C, Hulme AJ, Wong M, Lan Q, Cheung BB, Shi L, Wang JY, Simon T, Fischer M, Zhang XD, Marshall GM, Norris MD, Haber M, Vandesompele J, Li J, Mestdagh P, Hannan RD, Dinger ME, Perini G, Liu T.

Nat Commun. 2019 Nov 5;10(1):5026. doi: 10.1038/s41467-019-12971-3.


The usefulness of a novel patient management decision aid to improve clinical decision-making skills in final year chiropractic students.

Hobbs M, Crafford D, MacRae K, Hulme A, Whillier S, Jenkins H.

Chiropr Man Therap. 2019 Sep 19;27:55. doi: 10.1186/s12998-019-0278-3. eCollection 2019.


Kinetic analysis of bioorthogonal reaction mechanisms using Raman microscopy.

Tipping WJ, Lee M, Brunton VG, Lloyd-Jones GC, Hulme AN.

Faraday Discuss. 2019 Dec 2;220(0):71-85. doi: 10.1039/c9fd00057g.


Alkyne-Tagged PLGA Allows Direct Visualization of Nanoparticles In Vitro and Ex Vivo by Stimulated Raman Scattering Microscopy.

Vanden-Hehir S, Cairns SA, Lee M, Zoupi L, Shaver MP, Brunton VG, Williams A, Hulme AN.

Biomacromolecules. 2019 Oct 14;20(10):4008-4014. doi: 10.1021/acs.biomac.9b01092. Epub 2019 Aug 29.


The mosaic of general practice bulk billing in regional Victoria.

Glenister K, Disler R, Hulme A, Macharia D, Wright J.

Aust J Gen Pract. 2019 Jan-Feb;48(1-2):77-78. doi: 10.31128/AJGP-07-18-4659. No abstract available.


Musculoskeletal Anatomy Knowledge Retention in the Macquarie University Chiropractic Program: A Cross-Sectional Study.

Hulme AK, Luo K, Štrkalj G.

Anat Sci Educ. 2019 Mar 28. doi: 10.1002/ase.1879. [Epub ahead of print]


Raman Imaging of Nanocarriers for Drug Delivery.

Vanden-Hehir S, Tipping WJ, Lee M, Brunton VG, Williams A, Hulme AN.

Nanomaterials (Basel). 2019 Mar 3;9(3). pii: E341. doi: 10.3390/nano9030341. Review.


A Systems Approach to Performance Analysis in Women's Netball: Using Work Domain Analysis to Model Elite Netball Performance.

Mclean S, Hulme A, Mooney M, Read GJM, Bedford A, Salmon PM.

Front Psychol. 2019 Feb 6;10:201. doi: 10.3389/fpsyg.2019.00201. eCollection 2019.


A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors.

De Simone A, Georgiou C, Ioannidis H, Gupta AA, Juárez-Jiménez J, Doughty-Shenton D, Blackburn EA, Wear MA, Richards JP, Barlow PN, Carragher N, Walkinshaw MD, Hulme AN, Michel J.

Chem Sci. 2018 Oct 23;10(2):542-547. doi: 10.1039/c8sc03831g. eCollection 2019 Jan 14.


Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor.

Engel M, Gee YS, Cross D, Maccarone A, Heng B, Hulme A, Smith G, Guillemin GJ, Stringer BW, Hyland CJT, Ooi L.

J Neurochem. 2019 May;149(4):535-550. doi: 10.1111/jnc.14655. Epub 2019 Feb 3.


The Association Between Changes in Weekly Running Distance and Running-Related Injury: Preparing for a Half Marathon.

Damsted C, Parner ET, Sørensen H, Malisoux L, Hulme A, Nielsen RØ.

J Orthop Sports Phys Ther. 2019 Apr;49(4):230-238. doi: 10.2519/jospt.2019.8541. Epub 2018 Dec 7.


Bad behaviour or societal failure? Perceptions of the factors contributing to drivers' engagement in the fatal five driving behaviours.

Salmon PM, Read GJM, Beanland V, Thompson J, Filtness AJ, Hulme A, McClure R, Johnston I.

Appl Ergon. 2019 Jan;74:162-171. doi: 10.1016/j.apergo.2018.08.008. Epub 2018 Aug 30.


A novel fluorescein-bisphosphonate based diagnostic tool for the detection of hydroxyapatite in both cell and tissue models.

Sim AM, Rashdan NA, Cui L, Moss AJ, Nudelman F, Dweck MR, MacRae VE, Hulme AN.

Sci Rep. 2018 Nov 26;8(1):17360. doi: 10.1038/s41598-018-35454-9.


Computational methods to model complex systems in sports injury research: agent-based modelling (ABM) and systems dynamics (SD) modelling.

Hulme A, Mclean S, Salmon PM, Thompson J, Lane BR, Nielsen RO.

Br J Sports Med. 2019 Dec;53(24):1507-1510. doi: 10.1136/bjsports-2018-100098. Epub 2018 Nov 17. No abstract available.


Time-to-event analysis for sports injury research part 2: time-varying outcomes.

Nielsen RO, Bertelsen ML, Ramskov D, Møller M, Hulme A, Theisen D, Finch CF, Fortington LV, Mansournia MA, Parner ET.

Br J Sports Med. 2019 Jan;53(1):70-78. doi: 10.1136/bjsports-2018-100000. Epub 2018 Nov 9.


Time-to-event analysis for sports injury research part 1: time-varying exposures.

Nielsen RO, Bertelsen ML, Ramskov D, Møller M, Hulme A, Theisen D, Finch CF, Fortington LV, Mansournia MA, Parner ET.

Br J Sports Med. 2019 Jan;53(1):61-68. doi: 10.1136/bjsports-2018-099408. Epub 2018 Nov 9.


A Catch-and-Release Approach to Selective Modification of Accessible Tyrosine Residues.

Allan C, Kosar M, Burr CV, Mackay CL, Duncan RR, Hulme AN.

Chembiochem. 2018 Dec 4;19(23):2443-2447. doi: 10.1002/cbic.201800532. Epub 2018 Nov 5.


Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy.

Tipping WJ, Lee M, Serrels A, Brunton VG, Hulme AN.

Chem Sci. 2017 Aug 1;8(8):5606-5615. doi: 10.1039/c7sc01837a. Epub 2017 May 24.


Towards a complex systems approach in sports injury research: simulating running-related injury development with agent-based modelling.

Hulme A, Thompson J, Nielsen RO, Read GJM, Salmon PM.

Br J Sports Med. 2019 May;53(9):560-569. doi: 10.1136/bjsports-2017-098871. Epub 2018 Jun 18. Review.


Applying systems ergonomics methods in sport: A systematic review.

Hulme A, Thompson J, Plant KL, Read GJM, Mclean S, Clacy A, Salmon PM.

Appl Ergon. 2019 Oct;80:214-225. doi: 10.1016/j.apergo.2018.03.019. Epub 2018 Apr 16.


Injury prevalence across sports: a descriptive analysis on a representative sample of the Danish population.

Bueno AM, Pilgaard M, Hulme A, Forsberg P, Ramskov D, Damsted C, Nielsen RO.

Inj Epidemiol. 2018 Apr 2;5(1):6. doi: 10.1186/s40621-018-0136-0.


Use of ketamine sedation for the management of displaced paediatric forearm fractures.

Wiik AV, Patel P, Bovis J, Cowper A, Pastides PS, Hulme A, Evans S, Stewart C.

World J Orthop. 2018 Mar 18;9(3):50-57. doi: 10.5312/wjo.v9.i3.50. eCollection 2018 Mar 18.


Mono-Substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity.

McWhinnie FS, Sepp K, Wilson C, Kunath T, Hupp TR, Baker TS, Houston DR, Hulme AN.

Chemistry. 2018 Feb 9;24(9):2094-2097. doi: 10.1002/chem.201705983. Epub 2018 Jan 19.


Seven sins when interpreting statistics in sports injury science.

Nielsen RO, Chapman CM, Louis WR, Stovitz SD, Mansournia MA, Windt J, Møller M, Parner ET, Hulme A, Bertelsen ML, Finch CF, Casals M, Verhagen E.

Br J Sports Med. 2018 Nov;52(22):1410-1412. doi: 10.1136/bjsports-2017-098524. Epub 2017 Dec 20. No abstract available.


Are prevalence measures better than incidence measures in sports injury research?

Nielsen RO, Debes-Kristensen K, Hulme A, Bertelsen ML, Møller M, Parner ET, Mansournia MA.

Br J Sports Med. 2019 Apr;53(7):396-397. doi: 10.1136/bjsports-2017-098205. Epub 2017 Oct 13. No abstract available.



Johansen KK, Hulme A, Damsted C, Ramskov D, Nielsen RO.

Int J Sports Phys Ther. 2017 Aug;12(4):634-641.


From control to causation: Validating a 'complex systems model' of running-related injury development and prevention.

Hulme A, Salmon PM, Nielsen RO, Read GJM, Finch CF.

Appl Ergon. 2017 Nov;65:345-354. doi: 10.1016/j.apergo.2017.07.005. Epub 2017 Jul 29.


Training load and structure-specific load: applications for sport injury causality and data analyses.

Nielsen RO, Bertelsen ML, Møller M, Hulme A, Windt J, Verhagen E, Mansournia MA, Casals M, Parner ET.

Br J Sports Med. 2018 Aug;52(16):1016-1017. doi: 10.1136/bjsports-2017-097838. Epub 2017 Jul 24. No abstract available.


When is a study result important for athletes, clinicians and team coaches/staff?

Nielsen RO, Bertelsen ML, Verhagen E, Mansournia MA, Hulme A, Møller M, Casals M.

Br J Sports Med. 2017 Oct;51(20):1454-1455. doi: 10.1136/bjsports-2017-097759. Epub 2017 May 16. No abstract available.


Optimizing the Readout of Lanthanide-DOTA Complexes for the Detection of Ligand-Bound Copper(I).

Hanna JR, Allan C, Lawrence C, Meyer O, Wilson ND, Hulme AN.

Molecules. 2017 May 14;22(5). pii: E802. doi: 10.3390/molecules22050802.


A framework for the etiology of running-related injuries.

Bertelsen ML, Hulme A, Petersen J, Brund RK, Sørensen H, Finch CF, Parner ET, Nielsen RO.

Scand J Med Sci Sports. 2017 Nov;27(11):1170-1180. doi: 10.1111/sms.12883. Epub 2017 Apr 20. Review.


Risk and Protective Factors for Middle- and Long-Distance Running-Related Injury.

Hulme A, Nielsen RO, Timpka T, Verhagen E, Finch C.

Sports Med. 2017 May;47(5):869-886. doi: 10.1007/s40279-016-0636-4. Review.


Chloromethyl-triazole: a new motif for site-selective pseudo-acylation of proteins.

Brewster RC, Gavins GC, Günthardt B, Farr S, Webb KM, Voigt P, Hulme AN.

Chem Commun (Camb). 2016 Oct 6;52(82):12230-12232.


Self-Assembly of Disorazole C1 through a One-Pot Alkyne Metathesis Homodimerization Strategy.

Ralston KJ, Ramstadius HC, Brewster RC, Niblock HS, Hulme AN.

Angew Chem Weinheim Bergstr Ger. 2015 Jun 8;127(24):7192-7196. Epub 2015 Apr 29.


Naturally Inspired Peptide Leads: Alanine Scanning Reveals an Actin-Targeting Thiazole Analogue of Bisebromoamide.

Johnston HJ, Boys SK, Makda A, Carragher NO, Hulme AN.

Chembiochem. 2016 Sep 2;17(17):1621-7. doi: 10.1002/cbic.201600257. Epub 2016 Aug 5.


The epistemic basis of distance running injury research: A historical perspective.

Hulme A, Finch CF.

J Sport Health Sci. 2016 Jun;5(2):172-175. doi: 10.1016/j.jshs.2016.01.023. Epub 2016 Mar 11. No abstract available.


Stimulated Raman scattering microscopy: an emerging tool for drug discovery.

Tipping WJ, Lee M, Serrels A, Brunton VG, Hulme AN.

Chem Soc Rev. 2016 Apr 21;45(8):2075-89. doi: 10.1039/c5cs00693g. Epub 2016 Feb 3. Review.


Selective and Efficient Generation of ortho-Brominated para-Substituted Phenols in ACS-Grade Methanol.

Georgiev D, Saes BW, Johnston HJ, Boys SK, Healy A, Hulme AN.

Molecules. 2016 Jan 13;21(1):88. doi: 10.3390/molecules21010088.


Self-Assembly of Disorazole C1 through a One-Pot Alkyne Metathesis Homodimerization Strategy.

Ralston KJ, Ramstadius HC, Brewster RC, Niblock HS, Hulme AN.

Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7086-90. doi: 10.1002/anie.201501922. Epub 2015 Apr 29.


Diabetes Text-Message Self-Management Support Program (SMS4BG): A Pilot Study.

Dobson R, Carter K, Cutfield R, Hulme A, Hulme R, McNamara C, Maddison R, Murphy R, Shepherd M, Strydom J, Whittaker R.

JMIR Mhealth Uhealth. 2015 Mar 25;3(1):e32. doi: 10.2196/mhealth.3988.


Fluorescent image analysis of HIV-1 and HIV-2 uncoating kinetics in the presence of old world monkey TRIM5α.

Takeda E, Kono K, Hulme AE, Hope TJ, Nakayama EE, Shioda T.

PLoS One. 2015 Mar 24;10(3):e0121199. doi: 10.1371/journal.pone.0121199. eCollection 2015.


Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells.

Hulme AE, Kelley Z, Foley D, Hope TJ.

J Virol. 2015 May;89(10):5350-61. doi: 10.1128/JVI.00476-15. Epub 2015 Mar 4.


Live Cell Imaging of Retroviral Entry.

Hulme AE, Hope TJ.

Annu Rev Virol. 2014 Nov;1(1):501-15. doi: 10.1146/annurev-virology-031413-085502. Epub 2014 Jul 2.


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