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Items: 1 to 50 of 57

1.

Preclinical therapeutic targets in diffuse midline glioma.

Meel MH, Kaspers GJL, Hulleman E.

Drug Resist Updat. 2019 Jun 7;44:15-25. doi: 10.1016/j.drup.2019.06.001. [Epub ahead of print]

PMID:
31202081
2.

An efficient method for the transduction of primary pediatric glioma neurospheres.

Meel MH, Metselaar DS, Waranecki P, Kaspers GJL, Hulleman E.

MethodsX. 2018 Feb 27;5:173-183. doi: 10.1016/j.mex.2018.02.006. eCollection 2018.

3.

Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma.

Tsoli M, Shen H, Mayoh C, Franshaw L, Ehteda A, Upton D, Carvalho D, Vinci M, Meel MH, van Vuurden D, Plessier A, Castel D, Drissi R, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Francis S, Ludlow LEA, Carai A, Mastronuzzi A, Liu B, Hansford J, Gottardo NG, Hassall T, Kirby M, Fouladi M, Hawkins C, Monje M, Grill J, Jones C, Hulleman E, Ziegler DS.

J Neurooncol. 2019 Jan;141(2):265. doi: 10.1007/s11060-018-03060-4.

PMID:
30484110
4.

International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma.

Tsoli M, Shen H, Mayoh C, Franshaw L, Ehteda A, Upton D, Carvalho D, Vinci M, Meel MH, van Vuurden D, Plessier A, Castel D, Drissi R, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Francis S, Ludlow LEA, Carai A, Mastronuzzi A, Liu B, Hansford J, Gottardo N, Hassall T, Kirby M, Fouladi M, Hawkins C, Monje M, Grill J, Jones C, Hulleman E, Ziegler DS.

J Neurooncol. 2019 Jan;141(2):253-263. doi: 10.1007/s11060-018-03038-2. Epub 2018 Nov 16. Erratum in: J Neurooncol. 2018 Nov 27;:.

PMID:
30446898
5.

Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group.

Rutkowski S, Modena P, Williamson D, Kerl K, Nysom K, Pizer B, Bartels U, Puget S, Doz F, Michalski A, von Hoff K, Chevignard M, Avula S, Murray MJ, Schönberger S, Czech T, Schouten-van Meeteren AYN, Kordes U, Kramm CM, van Vuurden DG, Hulleman E, Janssens GO, Solanki GA, van Veelen MC, Thomale U, Schuhmann MU, Jones C, Giangaspero F, Figarella-Branger D, Pietsch T, Clifford SC, Pfister SM, Van Gool SW.

Lancet Oncol. 2018 Aug;19(8):e419-e428. doi: 10.1016/S1470-2045(18)30364-4. Review.

PMID:
30102236
6.

MELK Inhibition in Diffuse Intrinsic Pontine Glioma.

Meel MH, de Gooijer MC, Guillén Navarro M, Waranecki P, Breur M, Buil LCM, Wedekind LE, Twisk JWR, Koster J, Hashizume R, Raabe EH, Montero Carcaboso A, Bugiani M, van Tellingen O, van Vuurden DG, Kaspers GJL, Hulleman E.

Clin Cancer Res. 2018 Nov 15;24(22):5645-5657. doi: 10.1158/1078-0432.CCR-18-0924. Epub 2018 Jul 30.

PMID:
30061363
7.

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

Hoffman LM, Veldhuijzen van Zanten SEM, Colditz N, Baugh J, Chaney B, Hoffmann M, Lane A, Fuller C, Miles L, Hawkins C, Bartels U, Bouffet E, Goldman S, Leary S, Foreman NK, Packer R, Warren KE, Broniscer A, Kieran MW, Minturn J, Comito M, Broxson E, Shih CS, Khatua S, Chintagumpala M, Carret AS, Escorza NY, Hassall T, Ziegler DS, Gottardo N, Dholaria H, Doughman R, Benesch M, Drissi R, Nazarian J, Jabado N, Boddaert N, Varlet P, Giraud G, Castel D, Puget S, Jones C, Hulleman E, Modena P, Giagnacovo M, Antonelli M, Pietsch T, Gielen GH, Jones DTW, Sturm D, Pfister SM, Gerber NU, Grotzer MA, Pfaff E, von Bueren AO, Hargrave D, Solanki GA, Jadrijevic Cvrlje F, Kaspers GJL, Vandertop WP, Grill J, Bailey S, Biassoni V, Massimino M, Calmon R, Sanchez E, Bison B, Warmuth-Metz M, Leach J, Jones B, van Vuurden DG, Kramm CM, Fouladi M.

J Clin Oncol. 2018 Jul 1;36(19):1963-1972. doi: 10.1200/JCO.2017.75.9308. Epub 2018 May 10.

8.

Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas.

Mount CW, Majzner RG, Sundaresh S, Arnold EP, Kadapakkam M, Haile S, Labanieh L, Hulleman E, Woo PJ, Rietberg SP, Vogel H, Monje M, Mackall CL.

Nat Med. 2018 May;24(5):572-579. doi: 10.1038/s41591-018-0006-x. Epub 2018 Apr 16.

9.

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma.

Berlow NE, Svalina MN, Quist MJ, Settelmeyer TP, Zherebitskiy V, Kogiso M, Qi L, Du Y, Hawkins CE, Hulleman E, Li XN, Gultekin SH, Keller C.

PLoS One. 2018 Apr 5;13(4):e0193565. doi: 10.1371/journal.pone.0193565. eCollection 2018.

10.

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

Zomerman WW, Plasschaert SLA, Conroy S, Scherpen FJ, Meeuwsen-de Boer TGJ, Lourens HJ, Guerrero Llobet S, Smit MJ, Slagter-Menkema L, Seitz A, Gidding CEM, Hulleman E, Wesseling P, Meijer L, van Kempen LC, van den Berg A, Warmerdam DO, Kruyt FAE, Foijer F, van Vugt MATM, den Dunnen WFA, Hoving EW, Guryev V, de Bont ESJM, Bruggeman SWM.

Cell Rep. 2018 Mar 20;22(12):3206-3216. doi: 10.1016/j.celrep.2018.02.089.

11.

Signaling pathways and mesenchymal transition in pediatric high-grade glioma.

Meel MH, Schaper SA, Kaspers GJL, Hulleman E.

Cell Mol Life Sci. 2018 Mar;75(5):871-887. doi: 10.1007/s00018-017-2714-7. Epub 2017 Nov 21. Review.

12.

Effective Drug Delivery in Diffuse Intrinsic Pontine Glioma: A Theoretical Model to Identify Potential Candidates.

El-Khouly FE, van Vuurden DG, Stroink T, Hulleman E, Kaspers GJL, Hendrikse NH, Veldhuijzen van Zanten SEM.

Front Oncol. 2017 Oct 30;7:254. doi: 10.3389/fonc.2017.00254. eCollection 2017.

13.

Native T1 reference values for nonischemic cardiomyopathies and populations with increased cardiovascular risk: A systematic review and meta-analysis.

van den Boomen M, Slart RHJA, Hulleman EV, Dierckx RAJO, Velthuis BK, van der Harst P, Sosnovik DE, Borra RJH, Prakken NHJ.

J Magn Reson Imaging. 2018 Apr;47(4):891-912. doi: 10.1002/jmri.25885. Epub 2017 Nov 13. Review.

14.

Trimethylation of H3K27 during human cerebellar development in relation to medulloblastoma.

Mir SE, Smits M, Biesmans D, Julsing M, Bugiani M, Aronica E, Kaspers GJL, Cloos J, Würdinger T, Hulleman E.

Oncotarget. 2017 Sep 8;8(45):78978-78988. doi: 10.18632/oncotarget.20741. eCollection 2017 Oct 3.

15.

Deceptive morphologic and epigenetic heterogeneity in diffuse intrinsic pontine glioma.

Bugiani M, Veldhuijzen van Zanten SEM, Caretti V, Schellen P, Aronica E, Noske DP, Vandertop WP, Kaspers GJL, van Vuurden DG, Wesseling P, Hulleman E.

Oncotarget. 2017 Jul 31;8(36):60447-60452. doi: 10.18632/oncotarget.19726. eCollection 2017 Sep 1.

16.

Culture methods of diffuse intrinsic pontine glioma cells determine response to targeted therapies.

Meel MH, Sewing ACP, Waranecki P, Metselaar DS, Wedekind LE, Koster J, van Vuurden DG, Kaspers GJL, Hulleman E.

Exp Cell Res. 2017 Nov 15;360(2):397-403. doi: 10.1016/j.yexcr.2017.09.032. Epub 2017 Sep 22.

PMID:
28947132
17.

Multiregional Tumor Drug-Uptake Imaging by PET and Microvascular Morphology in End-Stage Diffuse Intrinsic Pontine Glioma.

Veldhuijzen van Zanten SEM, Sewing ACP, van Lingen A, Hoekstra OS, Wesseling P, Meel MH, van Vuurden DG, Kaspers GJL, Hulleman E, Bugiani M.

J Nucl Med. 2018 Apr;59(4):612-615. doi: 10.2967/jnumed.117.197897. Epub 2017 Aug 17.

18.

Erratum to: Identification of a restriction point at the M/G1 transition in CHO cells.

Hulleman E, Bijvelt JJM, Verkleij AJ, Verrips CT, Boonstra J.

Cell Mol Life Sci. 2017 Oct;74(19):3647. doi: 10.1007/s00018-017-2548-3. No abstract available.

PMID:
28584894
19.

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.

Nagaraja S, Vitanza NA, Woo PJ, Taylor KR, Liu F, Zhang L, Li M, Meng W, Ponnuswami A, Sun W, Ma J, Hulleman E, Swigut T, Wysocka J, Tang Y, Monje M.

Cancer Cell. 2017 May 8;31(5):635-652.e6. doi: 10.1016/j.ccell.2017.03.011. Epub 2017 Apr 20.

20.

Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma.

Sewing ACP, Lagerweij T, van Vuurden DG, Meel MH, Veringa SJE, Carcaboso AM, Gaillard PJ, Peter Vandertop W, Wesseling P, Noske D, Kaspers GJL, Hulleman E.

J Neurosurg Pediatr. 2017 May;19(5):518-530. doi: 10.3171/2016.9.PEDS16152. Epub 2017 Feb 17.

PMID:
28291423
21.

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease.

Veldhuijzen van Zanten SE, Baugh J, Chaney B, De Jongh D, Sanchez Aliaga E, Barkhof F, Noltes J, De Wolf R, Van Dijk J, Cannarozzo A, Damen-Korbijn CM, Lieverst JA, Colditz N, Hoffmann M, Warmuth-Metz M, Bison B, Jones DT, Sturm D, Gielen GH, Jones C, Hulleman E, Calmon R, Castel D, Varlet P, Giraud G, Slavc I, Van Gool S, Jacobs S, Jadrijevic-Cvrlje F, Sumerauer D, Nysom K, Pentikainen V, Kivivuori SM, Leblond P, Entz-Werle N, von Bueren AO, Kattamis A, Hargrave DR, Hauser P, Garami M, Thorarinsdottir HK, Pears J, Gandola L, Rutkauskiene G, Janssens GO, Torsvik IK, Perek-Polnik M, Gil-da-Costa MJ, Zheludkova O, Shats L, Deak L, Kitanovski L, Cruz O, Morales La Madrid A, Holm S, Gerber N, Kebudi R, Grundy R, Lopez-Aguilar E, Zapata-Tarres M, Emmerik J, Hayden T, Bailey S, Biassoni V, Massimino M, Grill J, Vandertop WP, Kaspers GJ, Fouladi M, Kramm CM, van Vuurden DG; members of the SIOPE DIPG Network.

J Neurooncol. 2017 Apr;132(2):255-266. doi: 10.1007/s11060-016-2363-y. Epub 2017 Jan 21.

22.

Bevacizumab Targeting Diffuse Intrinsic Pontine Glioma: Results of 89Zr-Bevacizumab PET Imaging in Brain Tumor Models.

Jansen MH, Lagerweij T, Sewing AC, Vugts DJ, van Vuurden DG, Molthoff CF, Caretti V, Veringa SJ, Petersen N, Carcaboso AM, Noske DP, Vandertop WP, Wesseling P, van Dongen GA, Kaspers GJ, Hulleman E.

Mol Cancer Ther. 2016 Sep;15(9):2166-74. doi: 10.1158/1535-7163.MCT-15-0558. Epub 2016 Jun 20.

23.

No Significant Cytotoxic Effect of the EZH2 Inhibitor Tazemetostat (EPZ-6438) on Pediatric Glioma Cells with Wildtype Histone 3 or Mutated Histone 3.3.

Wiese M, Schill F, Sturm D, Pfister S, Hulleman E, Johnsen SA, Kramm CM.

Klin Padiatr. 2016 Apr;228(3):113-7. doi: 10.1055/s-0042-105292. Epub 2016 May 2.

PMID:
27135271
24.

A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer.

Lagerweij T, Hiddingh L, Biesmans D, Crommentuijn MH, Cloos J, Li XN, Kogiso M, Tannous BA, Vandertop WP, Noske DP, Kaspers GJ, Würdinger T, Hulleman E.

Oncotarget. 2016 Jun 14;7(24):35776-35788. doi: 10.18632/oncotarget.7980.

25.

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M.

Nat Med. 2015 Jul;21(7):827. doi: 10.1038/nm0715-827a. No abstract available.

PMID:
26151328
26.

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M.

Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. Epub 2015 May 4. Erratum in: Nat Med. 2015 Jul;21(7):827.

27.

Convection enhanced delivery of carmustine to the murine brainstem: a feasibility study.

Sewing AC, Caretti V, Lagerweij T, Schellen P, Jansen MH, van Vuurden DG, Idema S, Molthoff CF, Vandertop WP, Kaspers GJ, Noske DP, Hulleman E.

J Neurosci Methods. 2014 Dec 30;238:88-94. doi: 10.1016/j.jneumeth.2014.09.020. Epub 2014 Sep 27.

PMID:
25263805
28.

A dual program for translation regulation in cellular proliferation and differentiation.

Gingold H, Tehler D, Christoffersen NR, Nielsen MM, Asmar F, Kooistra SM, Christophersen NS, Christensen LL, Borre M, Sørensen KD, Andersen LD, Andersen CL, Hulleman E, Wurdinger T, Ralfkiær E, Helin K, Grønbæk K, Ørntoft T, Waszak SM, Dahan O, Pedersen JS, Lund AH, Pilpel Y.

Cell. 2014 Sep 11;158(6):1281-1292. doi: 10.1016/j.cell.2014.08.011.

29.

Subventricular spread of diffuse intrinsic pontine glioma.

Caretti V, Bugiani M, Freret M, Schellen P, Jansen M, van Vuurden D, Kaspers G, Fisher PG, Hulleman E, Wesseling P, Vogel H, Monje M.

Acta Neuropathol. 2014 Oct;128(4):605-7. doi: 10.1007/s00401-014-1307-x. Epub 2014 Jun 15. No abstract available.

30.

Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis.

Hiddingh L, Raktoe RS, Jeuken J, Hulleman E, Noske DP, Kaspers GJ, Vandertop WP, Wesseling P, Wurdinger T.

Sci Rep. 2014 Jun 11;4:5260. doi: 10.1038/srep05260.

31.

Human pontine glioma cells can induce murine tumors.

Caretti V, Sewing AC, Lagerweij T, Schellen P, Bugiani M, Jansen MH, van Vuurden DG, Navis AC, Horsman I, Vandertop WP, Noske DP, Wesseling P, Kaspers GJ, Nazarian J, Vogel H, Hulleman E, Monje M, Wurdinger T.

Acta Neuropathol. 2014;127(6):897-909. doi: 10.1007/s00401-014-1272-4. Epub 2014 Apr 29.

32.

Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: clinical and genetic characterization and target for therapy.

van Berge L, Hamilton EM, Linnankivi T, Uziel G, Steenweg ME, Isohanni P, Wolf NI, Krägeloh-Mann I, Brautaset NJ, Andrews PI, de Jong BA, al Ghamdi M, van Wieringen WN, Tannous BA, Hulleman E, Würdinger T, van Berkel CG, Polder E, Abbink TE, Struys EA, Scheper GC, van der Knaap MS; LBSL Research Group.

Brain. 2014 Apr;137(Pt 4):1019-29. doi: 10.1093/brain/awu026. Epub 2014 Feb 24.

PMID:
24566671
33.

EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.

Hiddingh L, Tannous BA, Teng J, Tops B, Jeuken J, Hulleman E, Boots-Sprenger SH, Vandertop WP, Noske DP, Kaspers GJ, Wesseling P, Wurdinger T.

Oncotarget. 2014 Jan 30;5(2):363-74.

34.

Pre-B-cell leukemia homeobox interacting protein 1 is overexpressed in astrocytoma and promotes tumor cell growth and migration.

van Vuurden DG, Aronica E, Hulleman E, Wedekind LE, Biesmans D, Malekzadeh A, Bugiani M, Geerts D, Noske DP, Vandertop WP, Kaspers GJ, Cloos J, Würdinger T, van der Stoop PP.

Neuro Oncol. 2014 Jul;16(7):946-59.

35.

In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma.

Veringa SJ, Biesmans D, van Vuurden DG, Jansen MH, Wedekind LE, Horsman I, Wesseling P, Vandertop WP, Noske DP, Kaspers GJ, Hulleman E.

PLoS One. 2013 Apr 29;8(4):e61512. doi: 10.1371/journal.pone.0061512. Print 2013.

36.

WEE1 kinase inhibition enhances the radiation response of diffuse intrinsic pontine gliomas.

Caretti V, Hiddingh L, Lagerweij T, Schellen P, Koken PW, Hulleman E, van Vuurden DG, Vandertop WP, Kaspers GJ, Noske DP, Wurdinger T.

Mol Cancer Ther. 2013 Feb;12(2):141-50. doi: 10.1158/1535-7163.MCT-12-0735. Epub 2012 Dec 27.

37.

Implementation of a multi-institutional diffuse intrinsic pontine glioma autopsy protocol and characterization of a primary cell culture.

Caretti V, Jansen MH, van Vuurden DG, Lagerweij T, Bugiani M, Horsman I, Wessels H, van der Valk P, Cloos J, Noske DP, Vandertop WP, Wesseling P, Wurdinger T, Hulleman E, Kaspers GJ.

Neuropathol Appl Neurobiol. 2013 Jun;39(4):426-36. doi: 10.1111/j.1365-2990.2012.01294.x.

PMID:
22845849
38.

EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion.

Sikkema AH, den Dunnen WF, Hulleman E, van Vuurden DG, Garcia-Manero G, Yang H, Scherpen FJ, Kampen KR, Hoving EW, Kamps WA, Diks SH, Peppelenbosch MP, de Bont ES.

Neuro Oncol. 2012 Sep;14(9):1125-35. doi: 10.1093/neuonc/nos130. Epub 2012 Jun 21.

39.

EZH2-regulated DAB2IP is a medulloblastoma tumor suppressor and a positive marker for survival.

Smits M, van Rijn S, Hulleman E, Biesmans D, van Vuurden DG, Kool M, Haberler C, Aronica E, Vandertop WP, Noske DP, Würdinger T.

Clin Cancer Res. 2012 Aug 1;18(15):4048-58. Epub 2012 Jun 13.

40.

Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.

Spijkers-Hagelstein JA, Schneider P, Hulleman E, de Boer J, Williams O, Pieters R, Stam RW.

Leukemia. 2012 Jun;26(6):1255-65. doi: 10.1038/leu.2011.388. Epub 2012 Jan 27.

PMID:
22282267
41.

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation.

van Vuurden DG, Hulleman E, Meijer OL, Wedekind LE, Kool M, Witt H, Vandertop PW, Würdinger T, Noske DP, Kaspers GJ, Cloos J.

Oncotarget. 2011 Dec;2(12):984-96.

42.

Blood platelets contain tumor-derived RNA biomarkers.

Nilsson RJ, Balaj L, Hulleman E, van Rijn S, Pegtel DM, Walraven M, Widmark A, Gerritsen WR, Verheul HM, Vandertop WP, Noske DP, Skog J, Würdinger T.

Blood. 2011 Sep 29;118(13):3680-3. doi: 10.1182/blood-2011-03-344408. Epub 2011 Aug 10.

43.

miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis.

Smits M, Nilsson J, Mir SE, van der Stoop PM, Hulleman E, Niers JM, de Witt Hamer PC, Marquez VE, Cloos J, Krichevsky AM, Noske DP, Tannous BA, Würdinger T.

Oncotarget. 2010 Dec;1(8):710-20.

44.

Monitoring of tumor growth and post-irradiation recurrence in a diffuse intrinsic pontine glioma mouse model.

Caretti V, Zondervan I, Meijer DH, Idema S, Vos W, Hamans B, Bugiani M, Hulleman E, Wesseling P, Vandertop WP, Noske DP, Kaspers G, Molthoff CF, Wurdinger T.

Brain Pathol. 2011 Jul;21(4):441-51. doi: 10.1111/j.1750-3639.2010.00468.x. Epub 2010 Dec 29.

PMID:
21159008
45.

Expression of the transcription factor HEY1 in glioblastoma: a preliminary clinical study.

Gaetani P, Hulleman E, Levi D, Quarto M, Scorsetti M, Helins K, Simonelli M, Colombo P, Baena y Rodriguez R.

Tumori. 2010 Jan-Feb;96(1):97-102.

PMID:
20437865
46.

Pyruvate kinase M2 and prednisolone resistance in acute lymphoblastic leukemia.

Hulleman E, Broekhuis MJ, Pieters R, Den Boer ML.

Haematologica. 2009 Sep;94(9):1322-4. doi: 10.3324/haematol.2009.011437. No abstract available.

47.

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells.

Hulleman E, Kazemier KM, Holleman A, VanderWeele DJ, Rudin CM, Broekhuis MJ, Evans WE, Pieters R, Den Boer ML.

Blood. 2009 Feb 26;113(9):2014-21. doi: 10.1182/blood-2008-05-157842. Epub 2008 Oct 31.

48.

A role for the transcription factor HEY1 in glioblastoma.

Hulleman E, Quarto M, Vernell R, Masserdotti G, Colli E, Kros JM, Levi D, Gaetani P, Tunici P, Finocchiaro G, Baena RR, Capra M, Helin K.

J Cell Mol Med. 2009 Jan;13(1):136-46. doi: 10.1111/j.1582-4934.2008.00307.x. Epub 2008 Mar 17.

49.

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation.

Adhikary S, Marinoni F, Hock A, Hulleman E, Popov N, Beier R, Bernard S, Quarto M, Capra M, Goettig S, Kogel U, Scheffner M, Helin K, Eilers M.

Cell. 2005 Nov 4;123(3):409-21.

50.

Molecular mechanisms in gliomagenesis.

Hulleman E, Helin K.

Adv Cancer Res. 2005;94:1-27. Review.

PMID:
16095998

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