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East Anglian Early Neolithic monument burial linked to contemporary Megaliths.

Scheib CL, Hui R, D'Atanasio E, Wohns AW, Inskip SA, Rose A, Cessford C, O'Connell TC, Robb JE, Evans C, Patten R, Kivisild T.

Ann Hum Biol. 2019 Jun 11:1-15. doi: 10.1080/03014460.2019.1623912. [Epub ahead of print]


Five-Year Overall Survival for Patients With Advanced Non‒Small-Cell Lung Cancer Treated With Pembrolizumab: Results From the Phase I KEYNOTE-001 Study.

Garon EB, Hellmann MD, Rizvi NA, Carcereny E, Leighl NB, Ahn MJ, Eder JP, Balmanoukian AS, Aggarwal C, Horn L, Patnaik A, Gubens M, Ramalingam SS, Felip E, Goldman JW, Scalzo C, Jensen E, Kush DA, Hui R.

J Clin Oncol. 2019 Jun 2:JCO1900934. doi: 10.1200/JCO.19.00934. [Epub ahead of print]


Using Pharmacy Data and Adherence to Define Long-Term Bisphosphonate Exposure in Women.

Izano MA, Neugebauer R, Ettinger B, Hui R, Chandra M, Adams AL, Niu F, Ott SM, Lo JC.

J Manag Care Spec Pharm. 2019 Jun;25(6):719-723. doi: 10.18553/jmcp.2019.25.6.719.


Rate of cancer progression as a predictive marker of efficacy of immunotherapy; an analysis in metastatic non-small-cell lung cancer.

Prasanna T, Arasaratnam M, Boyer M, McNeil C, Barnet MB, Asher R, Hui R, Nagrial A, Kao S.

Immunotherapy. 2019 Jun;11(8):657-665. doi: 10.2217/imt-2018-0180.


Tamoxifen-induced severe hot flashes and endoxifen levels: is dose reduction a safe and effective strategy?

Lee CI, Fox P, Balakrishnar B, Balleine RL, Gao B, Provan P, Coulter S, Liddle C, Hui R, Wong M, Gurney H, Wilcken N.

Breast. 2019 May 6;46:52-57. doi: 10.1016/j.breast.2019.05.009. [Epub ahead of print]


Inhaled corticosteroid-phobia and childhood asthma: Current understanding and management implications.

Hui RWH.

Paediatr Respir Rev. 2019 Apr 11. pii: S1526-0542(19)30035-1. doi: 10.1016/j.prrv.2019.03.009. [Epub ahead of print] Review.


Effectiveness and safety of secukinumab for psoriasis in real-world practice: analysis of subgroups stratified by prior biologic failure or reimbursement.

Ger TY, Huang YH, Hui RC, Tsai TF, Chiu HY.

Ther Adv Chronic Dis. 2019 Apr 17;10:2040622319843756. doi: 10.1177/2040622319843756. eCollection 2019.


Secular Trends in Long-Term Oral Bisphosphonate Use.

Juergens N, Ettinger B, Hui R, Chandra M, Lo JC.

J Gen Intern Med. 2019 Apr 22. doi: 10.1007/s11606-019-04934-7. [Epub ahead of print] No abstract available.


Aspirin reduced recurrent stroke risk in patients with lacunar stroke.

Kong T, Chen J, Sun K, Zhang W, Wang J, Song L, Wang D, Hui R.

Acta Neurol Scand. 2019 Jul;140(1):78-83. doi: 10.1111/ane.13105. Epub 2019 May 9.


Association of adipokines with hepatic steatosis and fibrosis in chronic hepatitis B patients on long-term nucleoside analogue.

Mak LY, Lee CH, Cheung KS, Wong DK, Liu F, Hui RW, Fung J, Xu A, Lam KS, Yuen MF, Seto WK.

Liver Int. 2019 Mar 25. doi: 10.1111/liv.14104. [Epub ahead of print]


[Moving forward to the next "seek treasures" frontier: precision cardiovascular medicine].

Hui RT, Song L, Kong T, Wang JZ, Zou YB, Liu Z, Hou Q.

Zhonghua Xin Xue Guan Bing Za Zhi. 2019 Mar 24;47(3):253-258. doi: 10.3760/cma.j.issn.0253-3758.2019.03.016. Chinese.


[Genetic tests and precision treatment for monogenic cardiovascular diseases: reliable, feasible and useful].

Hui RT, Zhang SY.

Zhonghua Xin Xue Guan Bing Za Zhi. 2019 Mar 24;47(3):171-174. doi: 10.3760/cma.j.issn.0253-3758.2019.03.002. Chinese.


Fibrosis evolution in chronic hepatitis B e antigen-negative patients across a 10-year interval.

Mak LY, Seto WK, Hui RW, Fung J, Wong DK, Lai CL, Yuen MF.

J Viral Hepat. 2019 Mar 21. doi: 10.1111/jvh.13095. [Epub ahead of print]


Pembrolizumab in patients with advanced non-small-cell lung cancer (KEYNOTE-001): 3-year results from an open-label, phase 1 study.

Leighl NB, Hellmann MD, Hui R, Carcereny E, Felip E, Ahn MJ, Eder JP, Balmanoukian AS, Aggarwal C, Horn L, Patnaik A, Gubens M, Ramalingam SS, Lubiniecki GM, Zhang J, Piperdi B, Garon EB.

Lancet Respir Med. 2019 Apr;7(4):347-357. doi: 10.1016/S2213-2600(18)30500-9. Epub 2019 Mar 12.


Towards predicting intracellular radiofrequency radiation effects.

Nielsen C, Hui R, Lui WY, Solov'yov IA.

PLoS One. 2019 Mar 14;14(3):e0213286. doi: 10.1371/journal.pone.0213286. eCollection 2019.


Patterns of care for stage III non-small cell lung cancer in Australia.

Parente P, Chan BA, Hughes BGM, Jasas K, Joshi R, Kao S, Hegi-Johnson F, Hui R, McLaughlin-Barrett S, Nordman I, Stone E.

Asia Pac J Clin Oncol. 2019 Jun;15(3):93-100. doi: 10.1111/ajco.13140. Epub 2019 Mar 14. Review.


Predictive value of in-hospital white blood cell count in Chinese patients with triple-vessel coronary disease.

Zhao X, Jiang L, Xu L, Tian J, Xu Y, Zhao Y, Feng X, Wu Y, Zhang Y, Wang D, Sun K, Xu J, Liu R, Xu B, Zhao W, Hui R, Gao R, Song L, Yuan J.

Eur J Prev Cardiol. 2019 May;26(8):872-882. doi: 10.1177/2047487319826398. Epub 2019 Jan 29.


A life support-based comprehensive treatment regimen dramatically lowers the in-hospital mortality of patients with fulminant myocarditis: a multiple center study.

Li S, Xu S, Li C, Ran X, Cui G, He M, Miao K, Zhao C, Yan J, Hui R, Zhou N, Wang Y, Jiang J, Zhang J, Wang D.

Sci China Life Sci. 2019 Mar;62(3):369-380. doi: 10.1007/s11427-018-9501-9. Epub 2019 Feb 28.


Prognostic Value of Plasma Big Endothelin-1 Level among Patients with Three-Vessel Disease: A Cohort Study.

Zhang C, Tian J, Jiang L, Xu L, Liu J, Zhao X, Feng X, Wang D, Zhang Y, Sun K, Xu B, Zhao W, Hui R, Gao R, Yuan J, Song L.

J Atheroscler Thromb. 2019 Mar 1. doi: 10.5551/jat.47324. [Epub ahead of print]


Evaluation of Outcomes After Initiating Triple Antidiabetic Therapy with a GLP-1 RA in an Integrated Health Care System.

Lee SM, Aboubechara N, Niu F, Ledesma VM, Patel YA, Millares M, Hui RL.

J Manag Care Spec Pharm. 2019 Mar;25(3):350-356. doi: 10.18553/jmcp.2019.25.3.350.


Long-term stimulation of angiotensin II induced endothelial senescence and dysfunction.

Li R, Mi X, Yang S, Yang Y, Zhang S, Hui R, Chen Y, Zhang W.

Exp Gerontol. 2019 May;119:212-220. doi: 10.1016/j.exger.2019.02.012. Epub 2019 Feb 16.


Pembrolizumab plus trastuzumab in trastuzumab-resistant, advanced, HER2-positive breast cancer (PANACEA): a single-arm, multicentre, phase 1b-2 trial.

Loi S, Giobbie-Hurder A, Gombos A, Bachelot T, Hui R, Curigliano G, Campone M, Biganzoli L, Bonnefoi H, Jerusalem G, Bartsch R, Rabaglio-Poretti M, Kammler R, Maibach R, Smyth MJ, Di Leo A, Colleoni M, Viale G, Regan MM, André F; International Breast Cancer Study Group and the Breast International Group.

Lancet Oncol. 2019 Mar;20(3):371-382. doi: 10.1016/S1470-2045(18)30812-X. Epub 2019 Feb 11.


Predictors of time to relapse following ustekinumab withdrawal in patients with psoriasis who had responded to therapy: An eight-year multicenter study.

Chiu HY, Hui RC, Tsai TF, Chen YC, Chang Liao NF, Chen PH, Lai PJ, Wang TS, Huang YH.

J Am Acad Dermatol. 2019 Jan 28. pii: S0190-9622(19)30142-2. doi: 10.1016/j.jaad.2019.01.035. [Epub ahead of print]


Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.

Whitesell L, Robbins N, Huang DS, McLellan CA, Shekhar-Guturja T, LeBlanc EV, Nation CS, Hui R, Hutchinson A, Collins C, Chatterjee S, Trilles R, Xie JL, Krysan DJ, Lindquist S, Porco JA Jr, Tatu U, Brown LE, Pizarro J, Cowen LE.

Nat Commun. 2019 Jan 24;10(1):402. doi: 10.1038/s41467-018-08248-w.


China's treatment regimen for fulminant myocarditis is bringing wonderful achievement to the world.

Zhang J, Hang W, Hui R, Zhao Q, Desai SS.

Sci China Life Sci. 2019 Feb;62(2):282-284. doi: 10.1007/s11427-018-9445-2. Epub 2019 Jan 8. No abstract available.


Updated Analysis of KEYNOTE-024: Pembrolizumab Versus Platinum-Based Chemotherapy for Advanced Non-Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score of 50% or Greater.

Reck M, Rodríguez-Abreu D, Robinson AG, Hui R, Csőszi T, Fülöp A, Gottfried M, Peled N, Tafreshi A, Cuffe S, O'Brien M, Rao S, Hotta K, Vandormael K, Riccio A, Yang J, Pietanza MC, Brahmer JR.

J Clin Oncol. 2019 Mar 1;37(7):537-546. doi: 10.1200/JCO.18.00149. Epub 2019 Jan 8.


Prevalence and factors associated with fast resting heart rate in hypertensive and normotensive patients.

Li X, Kong T, Yao Y, Chen J, Sun K, Zhang S, Hui R, Fan X.

Clin Exp Hypertens. 2018 Dec 19:1-8. doi: 10.1080/10641963.2018.1557681. [Epub ahead of print]


Implications of Hyperuricemia in Severe Coronary Artery Disease.

Zhang C, Jiang L, Xu L, Tian J, Liu J, Zhao X, Feng X, Wang D, Zhang Y, Sun K, Xu B, Zhao W, Hui R, Gao R, Song L, Yuan J.

Am J Cardiol. 2019 Feb 15;123(4):558-564. doi: 10.1016/j.amjcard.2018.11.027. Epub 2018 Nov 23.


Prevalence and characteristics of apparent treatment-resistant hypertension in older people in China: a cross-sectional study.

Wu C, Wang Y, Zhang W, Li X, Wang L, Hui R.

Clin Exp Hypertens. 2018 Dec 4:1-6. doi: 10.1080/10641963.2018.1545852. [Epub ahead of print]


Determination of an isonicotinylhydrazide derivative, a novel positive inotropic compound, in mouse plasma by LC-MS/MS and its application to a pharmacokinetics study.

Hui R, Gao Y, Liu J, Liu H, Tang C, Feng B.

J Pharm Biomed Anal. 2019 Feb 20;165:12-17. doi: 10.1016/j.jpba.2018.10.034. Epub 2018 Oct 22.


Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study.

Adams S, Schmid P, Rugo HS, Winer EP, Loirat D, Awada A, Cescon DW, Iwata H, Campone M, Nanda R, Hui R, Curigliano G, Toppmeyer D, O'Shaughnessy J, Loi S, Paluch-Shimon S, Tan AR, Card D, Zhao J, Karantza V, Cortés J.

Ann Oncol. 2019 Mar 1;30(3):397-404. doi: 10.1093/annonc/mdy517.


Mutation profile of FLNC gene and its prognostic relevance in patients with hypertrophic cardiomyopathy.

Cui H, Wang J, Zhang C, Wu G, Zhu C, Tang B, Zou Y, Huang X, Hui R, Song L, Wang S.

Mol Genet Genomic Med. 2018 Nov;6(6):1104-1113. doi: 10.1002/mgg3.488. Epub 2018 Nov 8.


A grounded theory analysis of the experiences of carers for people living with dementia from three BAME communities: Balancing the need for support against fears of being diminished.

Baghirathan S, Cheston R, Hui R, Chacon A, Shears P, Currie K.

Dementia (London). 2018 Oct 14:1471301218804714. doi: 10.1177/1471301218804714. [Epub ahead of print]


Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm.

Boyle F, Beith J, Burslem K, de Boer R, Hui R, Lim E, McCarthy N, Redfern A, Woodward N.

Asia Pac J Clin Oncol. 2018 Oct;14 Suppl 4:3-11. doi: 10.1111/ajco.13064.


Emerging data and future directions for CDK4/6 inhibitor treatment of patients with hormone receptor positive HER2-non-amplified metastatic breast cancer.

Lim E, Beith J, Boyle F, de Boer R, Hui R, McCarthy N, Redfern A, Wade T, Woodward N.

Asia Pac J Clin Oncol. 2018 Oct;14 Suppl 4:12-21. doi: 10.1111/ajco.13065.


Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC.

Antonia SJ, Villegas A, Daniel D, Vicente D, Murakami S, Hui R, Kurata T, Chiappori A, Lee KH, de Wit M, Cho BC, Bourhaba M, Quantin X, Tokito T, Mekhail T, Planchard D, Kim YC, Karapetis CS, Hiret S, Ostoros G, Kubota K, Gray JE, Paz-Ares L, de Castro Carpeño J, Faivre-Finn C, Reck M, Vansteenkiste J, Spigel DR, Wadsworth C, Melillo G, Taboada M, Dennis PA, Özgüroğlu M; PACIFIC Investigators.

N Engl J Med. 2018 Dec 13;379(24):2342-2350. doi: 10.1056/NEJMoa1809697. Epub 2018 Sep 25.


Molecular epidemiology of coxsackievirus A6 circulating in Hong Kong reveals common neurological manifestations and emergence of novel recombinant groups.

Lau SKP, Zhao PSH, Sridhar S, Yip CCY, Aw-Yong KL, Chow EYY, Cheung KCM, Hui RWH, Leung RYH, Lai YSK, Wu AKL, To KKW, Woo PCY, Yuen KY.

J Clin Virol. 2018 Nov;108:43-49. doi: 10.1016/j.jcv.2018.09.002. Epub 2018 Sep 8.


Detecting archaic introgression using an unadmixed outgroup.

Skov L, Hui R, Shchur V, Hobolth A, Scally A, Schierup MH, Durbin R.

PLoS Genet. 2018 Sep 18;14(9):e1007641. doi: 10.1371/journal.pgen.1007641. eCollection 2018 Sep.


Augmented Reality Games as a New Class of Physical Activity Interventions? The Impact of Pokémon Go Use and Gaming Intensity on Physical Activity.

Ni MY, Hui RWH, Li TK, Tam AHM, Choy LLY, Ma KKW, Cheung F, Leung GM.

Games Health J. 2019 Feb;8(1):1-6. doi: 10.1089/g4h.2017.0181. Epub 2018 Aug 28.


The effect of levamisole in the treatment of recalcitrant recurrent erythema multiforme major: An observational study.

Liu RF, Chen CB, Hui RCY, Kuan YZ, Chung WH.

J Dermatol Sci. 2018 Oct;92(1):38-44. doi: 10.1016/j.jdermsci.2018.08.002. Epub 2018 Aug 8.


Clinical heterogeneity of human parvovirus B19 infection following adult liver transplantation.

Zhang J, Ren B, Hui R, Sun Y, Liu Z, Zhou S.

Medicine (Baltimore). 2018 Aug;97(34):e12074. doi: 10.1097/MD.0000000000012074.


Safety Profile of Secukinumab in Treatment of Patients with Psoriasis and Concurrent Hepatitis B or C: A Multicentric Prospective Cohort Study.

Chiu HY, Hui RC, Huang YH, Huang RY, Chen KL, Tsai YC, Lai PJ, Wang TS, Tsai TF.

Acta Derm Venereol. 2018 Oct 10;98(9):829-834. doi: 10.2340/00015555-2989.


Hydrological response of biological soil crusts to global warming: A ten-year simulative study.

Li XR, Jia RL, Zhang ZS, Zhang P, Hui R.

Glob Chang Biol. 2018 Oct;24(10):4960-4971. doi: 10.1111/gcb.14378. Epub 2018 Jul 18.


MicroRNA-216a promotes M1 macrophages polarization and atherosclerosis progression by activating telomerase via the Smad3/NF-κB pathway.

Yang S, Li J, Chen Y, Zhang S, Feng C, Hou Z, Cai J, Wang Y, Hui R, Lv B, Zhang W.

Biochim Biophys Acta Mol Basis Dis. 2019 Jul 1;1865(7):1772-1781. doi: 10.1016/j.bbadis.2018.06.016. Epub 2018 Jun 27.


Effects of Blood Pressure in the Early Phase of Ischemic Stroke and Stroke Subtype on Poststroke Cognitive Impairment.

He M, Wang J, Liu N, Xiao X, Geng S, Meng P, Ji N, Sun Y, Xu B, Xu Y, Zhou X, Zhang G, He X, Cai Z, Li Z, Wang B, Xu B, Hui R, Wang Y.

Stroke. 2018 Jul;49(7):1610-1617. doi: 10.1161/STROKEAHA.118.020827. Epub 2018 Jun 12.


Severe cutaneous adverse reactions induced by targeted anticancer therapies and immunotherapies.

Chen CB, Wu MY, Ng CY, Lu CW, Wu J, Kao PH, Yang CK, Peng MT, Huang CY, Chang WC, Hui RC, Yang CH, Yang SF, Chung WH, Su SC.

Cancer Manag Res. 2018 May 17;10:1259-1273. doi: 10.2147/CMAR.S163391. eCollection 2018. Review.


Structural characterization and α-glucosidase inhibitory activity of polysaccharides extracted from Chinese traditional medicine Huidouba.

Chen J, Li L, Zhou X, Li B, Zhang X, Hui R.

Int J Biol Macromol. 2018 Oct 1;117:815-819. doi: 10.1016/j.ijbiomac.2018.05.192. Epub 2018 May 26.


Blood pressures immediately following ischemic strokes are associated with cerebral perfusion and neurologic function.

He M, Cui B, Wu C, Meng P, Wu T, Wang M, Yang R, Zhou L, He X, Xu B, Li Z, Xu B, Cai Z, Sun Y, Hui R, Wang Y.

J Clin Hypertens (Greenwich). 2018 Jun;20(6):1008-1015. doi: 10.1111/jch.13310. Epub 2018 May 23.


Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.

Gandhi L, Rodríguez-Abreu D, Gadgeel S, Esteban E, Felip E, De Angelis F, Domine M, Clingan P, Hochmair MJ, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Boyer M, Rubio-Viqueira B, Novello S, Kurata T, Gray JE, Vida J, Wei Z, Yang J, Raftopoulos H, Pietanza MC, Garassino MC; KEYNOTE-189 Investigators.

N Engl J Med. 2018 May 31;378(22):2078-2092. doi: 10.1056/NEJMoa1801005. Epub 2018 Apr 16.

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