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Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy.

Ryu JY, Won EJ, Lee HAR, Kim JH, Hui E, Kim HP, Yoon TJ.

Biomaterials. 2020 Feb;232:119736. doi: 10.1016/j.biomaterials.2019.119736. Epub 2019 Dec 28.


Bi-functional IgG-lysosomal enzyme fusion proteins for brain drug delivery.

Boado RJ, Lu JZ, Hui EK, Lin H, Pardridge WM.

Sci Rep. 2019 Dec 9;9(1):18632. doi: 10.1038/s41598-019-55136-4.


PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.

Zhao Y, Lee CK, Lin CH, Gassen RB, Xu X, Huang Z, Xiao C, Bonorino C, Lu LF, Bui JD, Hui E.

Immunity. 2019 Dec 17;51(6):1059-1073.e9. doi: 10.1016/j.immuni.2019.11.003. Epub 2019 Nov 19.


MRF-ZOOM for the unbalanced steady-state free precession (ubSSFP) magnetic resonance fingerprinting.

Wang Z, Cui D, Zhang J, Wu EX, Hui ES.

Magn Reson Imaging. 2020 Jan;65:146-154. doi: 10.1016/j.mri.2019.11.010. Epub 2019 Nov 11.


Negative Affect Shared with Siblings is Associated with Structural Brain Network Efficiency and Loneliness in Adolescents.

Wong NML, Shao R, Yeung PPS, Khong PL, Hui ES, Schooling CM, Leung GM, Lee TMC.

Neuroscience. 2019 Nov 21;421:39-47. doi: 10.1016/j.neuroscience.2019.09.028. Epub 2019 Oct 31.


Spatiotemporal Control of Viscoelasticity in Phototunable Hyaluronic Acid Hydrogels.

Hui E, Gimeno KI, Guan G, Caliari SR.

Biomacromolecules. 2019 Nov 11;20(11):4126-4134. doi: 10.1021/acs.biomac.9b00965. Epub 2019 Oct 22.


TCR-pMHC bond conformation controls TCR ligand discrimination.

Sasmal DK, Feng W, Roy S, Leung P, He Y, Cai C, Cao G, Lian H, Qin J, Hui E, Schreiber H, Adams EJ, Huang J.

Cell Mol Immunol. 2019 Sep 17. doi: 10.1038/s41423-019-0273-6. [Epub ahead of print]


Understanding T cell signaling using membrane reconstitution.

Hui E.

Immunol Rev. 2019 Sep;291(1):44-56. doi: 10.1111/imr.12767. Review.


Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases.

Lam WKJ, Jiang P, Chan KCA, Peng W, Shang H, Heung MMS, Cheng SH, Zhang H, Tse OYO, Raghupathy R, Ma BBY, Hui EP, Chan ATC, Woo JKS, Chiu RWK, Lo YMD.

Nat Commun. 2019 Jul 22;10(1):3256. doi: 10.1038/s41467-019-11226-5.


The association of liver function and quality of life of patients with liver cancer.

Li L, Mo F, Hui EP, Chan SL, Koh J, Tang NLS, Yu SCH, Yeo W.

BMC Gastroenterol. 2019 May 2;19(1):66. doi: 10.1186/s12876-019-0984-2.


Brain connectomic associations with traditional Chinese medicine diagnostic classification of major depressive disorder: a diffusion tensor imaging study.

Liu LY, Xu XP, Luo LY, Zhu CQ, Li YP, Wang PR, Zhang YY, Yang CY, Hou HT, Cao YL, Wang G, Hui ES, Zhang ZJ.

Chin Med. 2019 Apr 11;14:15. doi: 10.1186/s13020-019-0239-8. eCollection 2019.


Correlations of health-related quality of life with serum inflammatory indicators IL-8 and mIBI in patients with hepatocellular carcinoma.

Li L, Chan SL, Mo F, Hui EP, Koh J, Chan AKC, Tang NLS, Lee KF, Lai PBS, Yu SCH, Yeo W.

Cancer Manag Res. 2019 Apr 4;11:2719-2727. doi: 10.2147/CMAR.S178482. eCollection 2019.


Status of inflammation in relation to health related quality of life in hepatocellular carcinoma patients.

Li L, Chan SL, Mo F, Hui EP, Koh J, Chan AK, Tang NL, Chu CM, Hui J, Lee KF, Yu S, Yeo W.

Qual Life Res. 2019 Sep;28(9):2597-2607. doi: 10.1007/s11136-019-02190-0. Epub 2019 Apr 29.


Complementary roles of MRI and endoscopic examination in the early detection of nasopharyngeal carcinoma.

King AD, Woo JKS, Ai QY, Chan JSM, Lam WKJ, Tse IOL, Bhatia KS, Zee BCY, Hui EP, Ma BBY, Chiu RWK, van Hasselt AC, Chan ATC, Lo YMD, Chan KCA.

Ann Oncol. 2019 Jun 1;30(6):977-982. doi: 10.1093/annonc/mdz106.


Distinguishing early-stage nasopharyngeal carcinoma from benign hyperplasia using intravoxel incoherent motion diffusion-weighted MRI.

Ai QY, King AD, Chan JSM, Chen W, Chan KCA, Woo JKS, Zee BCY, Chan ATC, Poon DMC, Ma BBY, Hui EP, Ahuja AT, Vlantis AC, Yuan J.

Eur Radiol. 2019 Oct;29(10):5627-5634. doi: 10.1007/s00330-019-06133-8. Epub 2019 Mar 22.


Age-Specific Associations of Renal Impairment and Cerebral Small Vessel Disease Burden in Chinese with Ischaemic Stroke.

Lau KK, Tsang ACO, Teo KC, Li HL, Chu LK, Li JCH, Chan MK, Wan VHL, Hui ES, Mak HKF.

J Stroke Cerebrovasc Dis. 2019 May;28(5):1274-1280. doi: 10.1016/j.jstrokecerebrovasdis.2019.01.018. Epub 2019 Mar 8.


Immune checkpoint inhibitors.

Hui E.

J Cell Biol. 2019 Mar 4;218(3):740-741. doi: 10.1083/jcb.201810035. Epub 2019 Feb 13. Review. No abstract available.


Antibiotic management of acute pharyngitis in primary care.

Advisory Group on Antibiotic Stewardship Programme in Primary Care, Chan AMW, Au WWY, Chao DVK, Choi K, Choi KW, Choi SMY, Chow Y, Fan CYM, Ho PL, Hui EMT, Kwong KH, Kwong BYS, Lam TP, Lam ETK, Lau KW, Lui L, Ng KHL, Wong MCS, Wong TY, Yeung CF, You JHS, Yung RWH.

Hong Kong Med J. 2019 Feb;25(1):58-63. doi: 10.12809/hkmj187544. Epub 2019 Jan 31.


Extranodal extension is a criterion for poor outcome in patients with metastatic nodes from cancer of the nasopharynx.

Ai QY, King AD, Poon DMC, Mo FKF, Hui EP, Tong M, Ahuja AT, Ma BBY, Chan ATC.

Oral Oncol. 2019 Jan;88:124-130. doi: 10.1016/j.oraloncology.2018.11.007. Epub 2018 Nov 24.


Brief Report: Malignancies in Adults Living With HIV in Asia.

Jiamsakul A, Polizzotto M, Wen-Wei Ku S, Tanuma J, Hui E, Chaiwarith R, Kiertiburanakul S, Avihingasanon A, Yunihastuti E, Kumarasamy N, Ly PS, Pujari S, Ditangco R, Do CD, Merati TP, Kantipong P, Zhang F, Van Nguyen K, Kamarulzaman A, Choi JY, Sim BLH, Ng OT, Ross J, Wong W.

J Acquir Immune Defic Syndr. 2019 Mar 1;80(3):301-307. doi: 10.1097/QAI.0000000000001918.


Association between educational level and cardiovascular disease and all-cause mortality in patients with type 2 diabetes: a prospective study in the Joint Asia Diabetes Evaluation Program.

Wu H, Lau ES, Kong AP, Ma RC, Ozaki R, Cheung KK, Chow E, Tsang CC, Lau KP, Hui EM, So WY, Gasevic D, Wild SH, Chan JC, Luk A.

Clin Epidemiol. 2018 Oct 25;10:1561-1571. doi: 10.2147/CLEP.S177437. eCollection 2018.


Ten-year risk prediction models of complications and mortality of Chinese patients with diabetes mellitus in primary care in Hong Kong: a study protocol.

Wan EYF, Yu EYT, Chin WY, Fung CSC, Kwok RLP, Chao DVK, Chan KH, Hui EM, Tsui WWS, Tan KCB, Fong DYT, Lam CLK.

BMJ Open. 2018 Oct 15;8(10):e023070. doi: 10.1136/bmjopen-2018-023070.


Recommendations on prevention and screening for colorectal cancer in Hong Kong.

Lam TH, Wong KH, Chan KK, Chan MC, Chao DV, Cheung AN, Fan CY, Ho J, Hui EP, Lam KO, Law CK, Law WL, Loong HH, Ngan RK, Tsang TH, Wong MC, Yeung RM, Ying AC, Ching R.

Hong Kong Med J. 2018 Oct;24(5):521-526. doi: 10.12809/hkmj177095.


Magnetic Resonance Fingerprinting Using a Fast Dictionary Searching Algorithm: MRF-ZOOM.

Ze Wang, Jian Zhang, Di Cui, Jun Xie, Mengye Lyu, Hui ES, Wu EX.

IEEE Trans Biomed Eng. 2019 Jun;66(6):1526-1535. doi: 10.1109/TBME.2018.2874992. Epub 2018 Oct 9.


Immunoglobulin therapy and passive transfer of anti-HBc: too often forgotten.

Hui EP.

Lancet Haematol. 2018 Oct;5(10):e437-e438. doi: 10.1016/S2352-3026(18)30158-3. No abstract available.


Quantitative susceptibility mapping as an indicator of subcortical and limbic iron abnormality in Parkinson's disease with dementia.

Li DTH, Hui ES, Chan Q, Yao N, Chua SE, McAlonan GM, Pang SYY, Ho SL, Mak HKF.

Neuroimage Clin. 2018 Jul 27;20:365-373. doi: 10.1016/j.nicl.2018.07.028. eCollection 2018.


Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells.

Qiu X, Lombardo JA, Westerhof TM, Pennell M, Ng A, Alshetaiwi H, Luna BM, Nelson EL, Kessenbrock K, Hui EE, Haun JB.

Lab Chip. 2018 Sep 11;18(18):2776-2786. doi: 10.1039/c8lc00507a.


Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.

Zhao Y, Harrison DL, Song Y, Ji J, Huang J, Hui E.

Cell Rep. 2018 Jul 10;24(2):379-390.e6. doi: 10.1016/j.celrep.2018.06.054.


Analysis of Plasma Epstein-Barr Virus DNA in Nasopharyngeal Cancer After Chemoradiation to Identify High-Risk Patients for Adjuvant Chemotherapy: A Randomized Controlled Trial.

Chan ATC, Hui EP, Ngan RKC, Tung SY, Cheng ACK, Ng WT, Lee VHF, Ma BBY, Cheng HC, Wong FCS, Loong HHF, Tong M, Poon DMC, Ahuja AT, King AD, Wang K, Mo F, Zee BCY, Chan KCA, Lo YMD.

J Clin Oncol. 2018 Jul 10:JCO2018777847. doi: 10.1200/JCO.2018.77.7847. [Epub ahead of print]


Chronic disease self-management and cognitive training programme to improve diabetic control in older outpatients with memory complaints: a randomised trial.

Kwok TC, Ma CW, Leung SY, Lee J, So WY, Hui E.

Hong Kong Med J. 2018 Feb;24 Suppl 2(1):16-20. No abstract available.


Recommendations on prevention and screening for breast cancer in Hong Kong.

Lam TH, Wong KH, Chan KK, Chan MC, Chao DV, Cheung AN, Fan CY, Ho J, Hui EP, Lam KO, Law CK, Law WL, Loong HH, Ngan RK, Tsang TH, Wong MC, Yeung RM, Ying AC, Ching R.

Hong Kong Med J. 2018 Jun;24(3):298-306. doi: 10.12809/hkmj177037.


Preclinical evaluation of ribociclib and its synergistic effect in combination with alpelisib in non-keratinizing nasopharyngeal carcinoma.

Wong CH, Ma BBY, Hui CWC, Lo KW, Hui EP, Chan ATC.

Sci Rep. 2018 May 22;8(1):8010. doi: 10.1038/s41598-018-26201-1.


Sequencing-based counting and size profiling of plasma Epstein-Barr virus DNA enhance population screening of nasopharyngeal carcinoma.

Lam WKJ, Jiang P, Chan KCA, Cheng SH, Zhang H, Peng W, Tse OYO, Tong YK, Gai W, Zee BCY, Ma BBY, Hui EP, Chan ATC, Woo JKS, Chiu RWK, Lo YMD.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5115-E5124. doi: 10.1073/pnas.1804184115. Epub 2018 May 14.


The effect of the total small vessel disease burden on the structural brain network.

Xu X, Lau KK, Wong YK, Mak HKF, Hui ES.

Sci Rep. 2018 May 10;8(1):7442. doi: 10.1038/s41598-018-25917-4.


Heart Failure and Frailty in the Community-Living Elderly Population: What the UFO Study Will Tell Us.

Fung E, Hui E, Yang X, Lui LT, Cheng KF, Li Q, Fan Y, Sahota DS, Ma BHM, Lee JSW, Lee APW, Woo J.

Front Physiol. 2018 Apr 24;9:347. doi: 10.3389/fphys.2018.00347. eCollection 2018.


Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742).

Ma BBY, Lim WT, Goh BC, Hui EP, Lo KW, Pettinger A, Foster NR, Riess JW, Agulnik M, Chang AYC, Chopra A, Kish JA, Chung CH, Adkins DR, Cullen KJ, Gitlitz BJ, Lim DW, To KF, Chan KCA, Lo YMD, King AD, Erlichman C, Yin J, Costello BA, Chan ATC.

J Clin Oncol. 2018 May 10;36(14):1412-1418. doi: 10.1200/JCO.2017.77.0388. Epub 2018 Mar 27. Erratum in: J Clin Oncol. 2018 Aug 1;36(22):2360.


Prospective evaluation of plasma Epstein-Barr virus DNA clearance and fluorodeoxyglucose positron emission scan in assessing early response to chemotherapy in patients with advanced or recurrent nasopharyngeal carcinoma.

Ma B, Hui EP, King A, Leung SF, Kam MK, Mo F, Li L, Wang K, Loong H, Wong A, Chan CM, Chan KCA, Wong SCC, Lo YMD, Chan AT.

Br J Cancer. 2018 Apr;118(8):1051-1055. doi: 10.1038/s41416-018-0026-9. Epub 2018 Mar 20.


An injectable chitosan/chondroitin sulfate hydrogel with tunable mechanical properties for cell therapy/tissue engineering.

Alinejad Y, Adoungotchodo A, Hui E, Zehtabi F, Lerouge S.

Int J Biol Macromol. 2018 Jul 1;113:132-141. doi: 10.1016/j.ijbiomac.2018.02.069. Epub 2018 Feb 13.


Induction Chemotherapy plus Concurrent Chemoradiotherapy in Endemic Nasopharyngeal Carcinoma: Individual Patient Data Pooled Analysis of Four Randomized Trials.

Chen YP, Tang LL, Yang Q, Poh SS, Hui EP, Chan ATC, Ong WS, Tan T, Wee J, Li WF, Chen L, Ma BBY, Tong M, Tan SH, Cheah SL, Fong KW, Sommat K, Soong YL, Guo Y, Lin AH, Sun Y, Hong MH, Cao SM, Chen MY, Ma J.

Clin Cancer Res. 2018 Apr 15;24(8):1824-1833. doi: 10.1158/1078-0432.CCR-17-2656. Epub 2018 Feb 5.


Efficacy, Safety, and Pharmacokinetics of Axitinib in Nasopharyngeal Carcinoma: A Preclinical and Phase II Correlative Study.

Hui EP, Ma BBY, Loong HHF, Mo F, Li L, King AD, Wang K, Ahuja AT, Chan CML, Hui CWC, Wong CH, Chan ATC.

Clin Cancer Res. 2018 Mar 1;24(5):1030-1037. doi: 10.1158/1078-0432.CCR-17-1667. Epub 2018 Jan 4.


Ablative Chemoembolization for Hepatocellular Carcinoma: A Prospective Phase I Case-Control Comparison with Conventional Chemoembolization.

Yu SCH, Chan SL, Lee KF, Hui JWY, Hui EP, Chu CM, Chan AW, Cheung S, Li L, Wong J, Yeo WMM.

Radiology. 2018 Apr;287(1):340-348. doi: 10.1148/radiol.2017170154. Epub 2017 Dec 22.


An intramolecular tryptophan-condensation approach for peptide stapling.

Hui EY, Rout B, Tan YS, Verma CS, Chan KP, Johannes CW.

Org Biomol Chem. 2018 Jan 17;16(3):389-392. doi: 10.1039/c7ob02667f.


Reduction in Brain Heparan Sulfate with Systemic Administration of an IgG Trojan Horse-Sulfamidase Fusion Protein in the Mucopolysaccharidosis Type IIIA Mouse.

Boado RJ, Lu JZ, Hui EK, Pardridge WM.

Mol Pharm. 2018 Feb 5;15(2):602-608. doi: 10.1021/acs.molpharmaceut.7b00958. Epub 2017 Dec 29.


Long-Term Prognostic Implications of Cerebral Microbleeds in Chinese Patients With Ischemic Stroke.

Lau KK, Wong YK, Teo KC, Chang RSK, Tse MY, Hoi CP, Chan CY, Chan OL, Cheung RHK, Wong EKM, Kwan JSK, Hui ES, Mak HKF.

J Am Heart Assoc. 2017 Dec 7;6(12). pii: e007360. doi: 10.1161/JAHA.117.007360.


Concordance of FDG PET/CT metabolic tumour volume versus DW-MRI functional tumour volume with T2-weighted anatomical tumour volume in cervical cancer.

Lai AYT, Perucho JAU, Xu X, Hui ES, Lee EYP.

BMC Cancer. 2017 Dec 6;17(1):825. doi: 10.1186/s12885-017-3800-9.


Nasopharyngeal carcinoma: relationship between invasion of the prevertebral space and distant metastases.

Ai QY, Hu CW, Bhatia KS, Poon DMC, Hui EP, Mo FKF, Law BKH, Tong M, Ma BB, Chan ATC, King AD.

Eur Arch Otorhinolaryngol. 2018 Feb;275(2):497-505. doi: 10.1007/s00405-017-4825-z. Epub 2017 Nov 29.


How and Why Preclerkship Students Set Learning Goals and Assess Their Achievement: A Qualitative Exploration.

Kindler PM, Bates J, Hui E, Eva KW.

Acad Med. 2017 Nov;92(11S Association of American Medical Colleges Learn Serve Lead: Proceedings of the 56th Annual Research in Medical Education Sessions):S61-S66. doi: 10.1097/ACM.0000000000001913.


Fast dictionary generation and searching for magnetic resonance fingerprinting.

Jun Xie, Mengye Lyu, Jian Zhang, Hui ES, Wu EX, Ze Wang.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:3256-3259. doi: 10.1109/EMBC.2017.8037551.


In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.

Carbone CB, Kern N, Fernandes RA, Hui E, Su X, Garcia KC, Vale RD.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9338-E9345. doi: 10.1073/pnas.1710358114. Epub 2017 Oct 17.

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