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Items: 15

1.

AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes.

Hui DJ, Edmonson SC, Podsakoff GM, Pien GC, Ivanciu L, Camire RM, Ertl H, Mingozzi F, High KA, Basner-Tschakarjan E.

Mol Ther Methods Clin Dev. 2015 Sep 30;2:15029. doi: 10.1038/mtm.2015.29. eCollection 2015.

2.

Overcoming preexisting humoral immunity to AAV using capsid decoys.

Mingozzi F, Anguela XM, Pavani G, Chen Y, Davidson RJ, Hui DJ, Yazicioglu M, Elkouby L, Hinderer CJ, Faella A, Howard C, Tai A, Podsakoff GM, Zhou S, Basner-Tschakarjan E, Wright JF, High KA.

Sci Transl Med. 2013 Jul 17;5(194):194ra92. doi: 10.1126/scitranslmed.3005795.

3.

Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes.

Hui DJ, Basner-Tschakarjan E, Chen Y, Davidson RJ, Buchlis G, Yazicioglu M, Pien GC, Finn JD, Haurigot V, Tai A, Scott DW, Cousens LP, Zhou S, De Groot AS, Mingozzi F.

Mol Ther. 2013 Sep;21(9):1727-37. doi: 10.1038/mt.2013.166. Epub 2013 Jul 16.

4.

Enhanced T cell function in a mouse model of human glycosylation.

Buchlis G, Odorizzi P, Soto PC, Pearce OM, Hui DJ, Jordan MS, Varki A, Wherry EJ, High KA.

J Immunol. 2013 Jul 1;191(1):228-37. doi: 10.4049/jimmunol.1202905. Epub 2013 May 24.

5.

Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.

Haurigot V, Mingozzi F, Buchlis G, Hui DJ, Chen Y, Basner-Tschakarjan E, Arruda VR, Radu A, Franck HG, Wright JF, Zhou S, Stedman HH, Bellinger DA, Nichols TC, High KA.

Mol Ther. 2010 Jul;18(7):1318-29. doi: 10.1038/mt.2010.73. Epub 2010 Apr 27.

6.

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells.

Mingozzi F, Meulenberg JJ, Hui DJ, Basner-Tschakarjan E, Hasbrouck NC, Edmonson SA, Hutnick NA, Betts MR, Kastelein JJ, Stroes ES, High KA.

Blood. 2009 Sep 3;114(10):2077-86. doi: 10.1182/blood-2008-07-167510. Epub 2009 Jun 8.

7.

Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors.

Pien GC, Basner-Tschakarjan E, Hui DJ, Mentlik AN, Finn JD, Hasbrouck NC, Zhou S, Murphy SL, Maus MV, Mingozzi F, Orange JS, High KA.

J Clin Invest. 2009 Jun;119(6):1688-95. doi: 10.1172/JCI36891. Epub 2009 May 11.

8.

Diverse IgG subclass responses to adeno-associated virus infection and vector administration.

Murphy SL, Li H, Mingozzi F, Sabatino DE, Hui DJ, Edmonson SA, High KA.

J Med Virol. 2009 Jan;81(1):65-74. doi: 10.1002/jmv.21360.

9.

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.

Mingozzi F, Hasbrouck NC, Basner-Tschakarjan E, Edmonson SA, Hui DJ, Sabatino DE, Zhou S, Wright JF, Jiang H, Pierce GF, Arruda VR, High KA.

Blood. 2007 Oct 1;110(7):2334-41. Epub 2007 Jul 3.

10.

CD8(+) T-cell responses to adeno-associated virus capsid in humans.

Mingozzi F, Maus MV, Hui DJ, Sabatino DE, Murphy SL, Rasko JE, Ragni MV, Manno CS, Sommer J, Jiang H, Pierce GF, Ertl HC, High KA.

Nat Med. 2007 Apr;13(4):419-22. Epub 2007 Mar 18.

PMID:
17369837
11.

Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56.

Terenzi F, Hui DJ, Merrick WC, Sen GC.

J Biol Chem. 2006 Nov 10;281(45):34064-71. Epub 2006 Sep 13.

12.

Identification of mouse AAV capsid-specific CD8+ T cell epitopes.

Sabatino DE, Mingozzi F, Hui DJ, Chen H, Colosi P, Ertl HC, High KA.

Mol Ther. 2005 Dec;12(6):1023-33. Epub 2005 Nov 2.

13.

Mouse p56 blocks a distinct function of eukaryotic initiation factor 3 in translation initiation.

Hui DJ, Terenzi F, Merrick WC, Sen GC.

J Biol Chem. 2005 Feb 4;280(5):3433-40. Epub 2004 Nov 23.

14.

Viral stress-inducible protein p56 inhibits translation by blocking the interaction of eIF3 with the ternary complex eIF2.GTP.Met-tRNAi.

Hui DJ, Bhasker CR, Merrick WC, Sen GC.

J Biol Chem. 2003 Oct 10;278(41):39477-82. Epub 2003 Jul 28.

15.

A new pathway of translational regulation mediated by eukaryotic initiation factor 3.

Guo J, Hui DJ, Merrick WC, Sen GC.

EMBO J. 2000 Dec 15;19(24):6891-9.

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