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Circulating tumor DNA analysis to assess risk of progression after long-term response to PD-(L)1 blockade in NSCLC.

Hellmann MD, Nabet BY, Rizvi H, Chaudhuri AA, Wells DK, Dunphy MP, Chabon JJ, Liu CL, Hui AB, Arbour KC, Luo J, Preeshagul IR, Moding EJ, Almanza D, Bonilla RF, Sauter JL, Choi H, Tenet M, Abu-Akeel M, Plodkowski AJ, Perez-Johnston R, Yoo CH, Ko RB, Stehr H, Gojenola L, Wakelee HA, Padda SK, Neal JW, Chaft JE, Kris MG, Rudin CM, Merghoub T, Li BT, Alizadeh AA, Diehn M.

Clin Cancer Res. 2020 Feb 11. pii: clincanres.3418.2019. doi: 10.1158/1078-0432.CCR-19-3418. [Epub ahead of print]


Functional significance of U2AF1 S34F mutations in lung adenocarcinomas.

Esfahani MS, Lee LJ, Jeon YJ, Flynn RA, Stehr H, Hui AB, Ishisoko N, Kildebeck E, Newman AM, Bratman SV, Porteus MH, Chang HY, Alizadeh AA, Diehn M.

Nat Commun. 2019 Dec 13;10(1):5712. doi: 10.1038/s41467-019-13392-y.


Circulating Tumor DNA Analysis for Detection of Minimal Residual Disease After Chemoradiotherapy for Localized Esophageal Cancer.

Azad TD, Chaudhuri AA, Fang P, Qiao Y, Esfahani MS, Chabon JJ, Hamilton EG, Yang YD, Lovejoy A, Newman AM, Kurtz DM, Jin M, Schroers-Martin J, Stehr H, Liu CL, Hui AB, Patel V, Maru D, Lin SH, Alizadeh AA, Diehn M.

Gastroenterology. 2020 Feb;158(3):494-505.e6. doi: 10.1053/j.gastro.2019.10.039. Epub 2019 Nov 9.


Reprogramming the immunological microenvironment through radiation and targeting Axl.

Aguilera TA, Rafat M, Castellini L, Shehade H, Kariolis MS, Hui AB, Stehr H, von Eyben R, Jiang D, Ellies LG, Koong AC, Diehn M, Rankin EB, Graves EE, Giaccia AJ.

Nat Commun. 2016 Dec 23;7:13898. doi: 10.1038/ncomms13898.


Developing a prognostic micro-RNA signature for human cervical carcinoma.

How C, Pintilie M, Bruce JP, Hui AB, Clarke BA, Wong P, Yin S, Yan R, Waggott D, Boutros PC, Fyles A, Hedley DW, Hill RP, Milosevic M, Liu FF.

PLoS One. 2015 Apr 16;10(4):e0123946. doi: 10.1371/journal.pone.0123946. eCollection 2015.


Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma.

Bruce JP, Hui AB, Shi W, Perez-Ordonez B, Weinreb I, Xu W, Haibe-Kains B, Waggott DM, Boutros PC, O'Sullivan B, Waldron J, Huang SH, Chen EX, Gilbert R, Liu FF.

Oncotarget. 2015 Feb 28;6(6):4537-50.


Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer.

Lenarduzzi M, Hui AB, Yue S, Ito E, Shi W, Williams J, Bruce J, Sakemura-Nakatsugawa N, Xu W, Schimmer A, Liu FF.

PLoS One. 2013 Aug 26;8(8):e74075. doi: 10.1371/journal.pone.0074075. eCollection 2013.


Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.

Chung GT, Lung RW, Hui AB, Yip KY, Woo JK, Chow C, Tong CY, Lee SD, Yuen JW, Lun SW, Tso KK, Wong N, Tsao SW, Yip TT, Busson P, Kim H, Seo JS, O'Sullivan B, Liu FF, To KF, Lo KW.

J Pathol. 2013 Oct;231(2):158-67. doi: 10.1002/path.4240.


MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

How C, Hui AB, Alajez NM, Shi W, Boutros PC, Clarke BA, Yan R, Pintilie M, Fyles A, Hedley DW, Hill RP, Milosevic M, Liu FF.

PLoS One. 2013 Jul 4;8(7):e67846. doi: 10.1371/journal.pone.0067846. Print 2013.


Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery.

Principe S, Hui AB, Bruce J, Sinha A, Liu FF, Kislinger T.

Proteomics. 2013 May;13(10-11):1608-23. doi: 10.1002/pmic.201200533. Review.


Potentially prognostic miRNAs in HPV-associated oropharyngeal carcinoma.

Hui AB, Lin A, Xu W, Waldron L, Perez-Ordonez B, Weinreb I, Shi W, Bruce J, Huang SH, O'Sullivan B, Waldron J, Gullane P, Irish JC, Chan K, Liu FF.

Clin Cancer Res. 2013 Apr 15;19(8):2154-62. doi: 10.1158/1078-0432.CCR-12-3572. Epub 2013 Mar 4.


MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1.

Lenarduzzi M, Hui AB, Alajez NM, Shi W, Williams J, Yue S, O'Sullivan B, Liu FF.

PLoS One. 2013;8(1):e53765. doi: 10.1371/journal.pone.0053765. Epub 2013 Jan 15.


Significance of dysregulated metadherin and microRNA-375 in head and neck cancer.

Hui AB, Bruce JP, Alajez NM, Shi W, Yue S, Perez-Ordonez B, Xu W, O'Sullivan B, Waldron J, Cummings B, Gullane P, Siu L, Liu FF.

Clin Cancer Res. 2011 Dec 15;17(24):7539-50. doi: 10.1158/1078-0432.CCR-11-2102. Epub 2011 Oct 26.


MicroRNA-301 mediates proliferation and invasion in human breast cancer.

Shi W, Gerster K, Alajez NM, Tsang J, Waldron L, Pintilie M, Hui AB, Sykes J, P'ng C, Miller N, McCready D, Fyles A, Liu FF.

Cancer Res. 2011 Apr 15;71(8):2926-37. doi: 10.1158/0008-5472.CAN-10-3369. Epub 2011 Mar 10.


MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway.

Alajez NM, Lenarduzzi M, Ito E, Hui AB, Shi W, Bruce J, Yue S, Huang SH, Xu W, Waldron J, O'Sullivan B, Liu FF.

Cancer Res. 2011 Mar 15;71(6):2381-91. doi: 10.1158/0008-5472.CAN-10-2754. Epub 2011 Mar 8.


Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98.

Alajez NM, Shi W, Hui AB, Bruce J, Lenarduzzi M, Ito E, Yue S, O'Sullivan B, Liu FF.

Cell Death Dis. 2010 Oct 21;1:e85. doi: 10.1038/cddis.2010.64.


Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer.

Ito E, Yue S, Moriyama EH, Hui AB, Kim I, Shi W, Alajez NM, Bhogal N, Li G, Datti A, Schimmer AD, Wilson BC, Liu PP, Durocher D, Neel BG, O'Sullivan B, Cummings B, Bristow R, Wrana J, Liu FF.

Sci Transl Med. 2011 Jan 26;3(67):67ra7. doi: 10.1126/scitranslmed.3001922.


Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas.

Hui AB, Lenarduzzi M, Krushel T, Waldron L, Pintilie M, Shi W, Perez-Ordonez B, Jurisica I, O'Sullivan B, Waldron J, Gullane P, Cummings B, Liu FF.

Clin Cancer Res. 2010 Feb 15;16(4):1129-39. doi: 10.1158/1078-0432.CCR-09-2166. Epub 2010 Feb 9.


Significance of Plk1 regulation by miR-100 in human nasopharyngeal cancer.

Shi W, Alajez NM, Bastianutto C, Hui AB, Mocanu JD, Ito E, Busson P, Lo KW, Ng R, Waldron J, O'Sullivan B, Liu FF.

Int J Cancer. 2010 May 1;126(9):2036-48. doi: 10.1002/ijc.24880.


Identification of a novel 12p13.3 amplicon in nasopharyngeal carcinoma.

Or YY, Chung GT, To KF, Chow C, Choy KW, Tong CY, Leung AW, Hui AB, Tsao SW, Ng HK, Yip TT, Busson P, Lo KW.

J Pathol. 2010 Jan;220(1):97-107. doi: 10.1002/path.2609.


Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy.

Alajez NM, Shi W, Hui AB, Yue S, Ng R, Lo KW, Bastianutto C, O'Sullivan B, Gullane P, Liu FF.

Cell Death Differ. 2009 Nov;16(11):1469-79. doi: 10.1038/cdd.2009.85. Epub 2009 Jul 3.


Therapeutic efficacy of seliciclib in combination with ionizing radiation for human nasopharyngeal carcinoma.

Hui AB, Yue S, Shi W, Alajez NM, Ito E, Green SR, Frame S, O'Sullivan B, Liu FF.

Clin Cancer Res. 2009 Jun 1;15(11):3716-24. doi: 10.1158/1078-0432.CCR-08-2790. Epub 2009 May 26.


Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues.

Hui AB, Shi W, Boutros PC, Miller N, Pintilie M, Fyles T, McCready D, Wong D, Gerster K, Waldron L, Jurisica I, Penn LZ, Liu FF.

Lab Invest. 2009 May;89(5):597-606. doi: 10.1038/labinvest.2009.12. Epub 2009 Mar 16. Erratum in: Lab Invest. 2009 Jun;89(6):726. Waldron, Levi [added].


Progressive increase of genetic alteration in urinary bladder cancer by combined allelotyping analysis and comparative genomic hybridization.

Chan MW, Hui AB, Yip SK, Ng CF, Lo KW, Tong JH, Chan AW, Cheung HY, Wong WS, Chan PS, Lai FM, To KF.

Int J Oncol. 2009 Apr;34(4):963-70.


Efficacy of systemically administered mutant vesicular stomatitis virus (VSVDelta51) combined with radiation for nasopharyngeal carcinoma.

Alajez NM, Mocanu JD, Shi W, Chia MC, Breitbach CJ, Hui AB, Knowles S, Bell JC, Busson P, Takada K, Lo KW, O'Sullivan B, Gullane P, Liu FF.

Clin Cancer Res. 2008 Aug 1;14(15):4891-7. doi: 10.1158/1078-0432.CCR-07-4134.


4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4.

Cheng SH, Ng MH, Lau KM, Liu HS, Chan JC, Hui AB, Lo KW, Jiang H, Hou J, Chu RW, Wong WS, Chan NP, Ng HK.

Blood. 2007 Mar 1;109(5):2089-99. Epub 2006 Oct 31.


Investigation of the genomic representation of plasma DNA in pregnant women by comparative genomic hybridization analysis: a feasibility study.

Chan KC, Hui AB, Wong N, Lau TK, Leung TN, Lo KW, Lo YM.

Clin Chem. 2005 Dec;51(12):2398-401. No abstract available.


Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinoma.

Hui AB, Or YY, Takano H, Tsang RK, To KF, Guan XY, Sham JS, Hung KW, Lam CN, van Hasselt CA, Kuo WL, Gray JW, Huang DP, Lo KW.

Cancer Res. 2005 Sep 15;65(18):8125-33.


PIK3CA mutations in nasopharyngeal carcinoma.

Or YY, Hui AB, To KF, Lam CN, Lo KW.

Int J Cancer. 2006 Feb 15;118(4):1065-7. No abstract available.


Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array comparative genomic hybridization analysis.

Hui AB, Takano H, Lo KW, Kuo WL, Lam CN, Tong CY, Chang Q, Gray JW, Ng HK.

Clin Cancer Res. 2005 Jul 1;11(13):4707-16.


Characterization of chromosome 3q and 12q amplicons in nasopharyngeal carcinoma cell lines.

Or YY, Hui AB, Tam KY, Huang DP, Lo KW.

Int J Oncol. 2005 Jan;26(1):49-56.


Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization.

Tong CY, Hui AB, Yin XL, Pang JC, Zhu XL, Poon WS, Ng HK.

J Neurosurg. 2004 Feb;100(2 Suppl Pediatrics):187-93.


Size distributions of maternal and fetal DNA in maternal plasma.

Chan KC, Zhang J, Hui AB, Wong N, Lau TK, Leung TN, Lo KW, Huang DW, Lo YM.

Clin Chem. 2004 Jan;50(1):88-92.


Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma.

Hui AB, Lo KW, Kwong J, Lam EC, Chan SY, Chow LS, Chan AS, Teo PM, Huang DP.

Mol Carcinog. 2003 Dec;38(4):170-8.


Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping.

Wong N, Hui AB, Fan B, Lo KW, Pang E, Leung SF, Huang DP, Johnson PJ.

Cancer Genet Cytogenet. 2003 Jan 15;140(2):124-32.


Genome-wide survey for chromosomal imbalances in ganglioglioma using comparative genomic hybridization.

Yin XL, Hui AB, Pang JC, Poon WS, Ng HK.

Cancer Genet Cytogenet. 2002 Apr 1;134(1):71-6.


Absence of SDHD mutations in primary nasopharyngeal carcinomas.

Hui AB, Lo KW, Chan SY, Kwong J, Chan AS, Huang DP.

Int J Cancer. 2002 Feb 20;97(6):875-7. No abstract available.


Genome wide detection of oncogene amplifications in nasopharyngeal carcinoma by array based comparative genomic hybridization.

Hui AB, Lo KW, Teo PM, To KF, Huang DP.

Int J Oncol. 2002 Mar;20(3):467-73. Erratum in: Int J Oncol. 2002 Aug;21(2):451..


Genetic imbalances in pleomorphic xanthoastrocytoma detected by comparative genomic hybridization and literature review.

Yin XL, Hui AB, Liong EC, Ding M, Chang AR, Ng HK.

Cancer Genet Cytogenet. 2002 Jan 1;132(1):14-9. Review.


High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma.

Lo KW, Kwong J, Hui AB, Chan SY, To KF, Chan AS, Chow LS, Teo PM, Johnson PJ, Huang DP.

Cancer Res. 2001 May 15;61(10):3877-81.


Central neurocytomas are genetically distinct from oligodendrogliomas and neuroblastomas.

Tong CY, Ng HK, Pang JC, Hu J, Hui AB, Poon WS.

Histopathology. 2000 Aug;37(2):160-5.


High resolution allelotype of microdissected primary nasopharyngeal carcinoma.

Lo KW, Teo PM, Hui AB, To KF, Tsang YS, Chan SY, Mak KF, Lee JC, Huang DP.

Cancer Res. 2000 Jul 1;60(13):3348-53.


Detection of chromosomal imbalances in central neurocytomas by using comparative genomic hybridization.

Yin XL, Pang JC, Hui AB, Ng HK.

J Neurosurg. 2000 Jul;93(1):77-81.


Establishment and characterization of a human cell line from paediatric cerebellar glioblastoma multiforme.

Di Tomaso E, Pang JC, Lam HK, Tian XX, Suen KW, Hui AB, Hjelm NM.

Neuropathol Appl Neurobiol. 2000 Feb;26(1):22-30.


Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus.

Cheung ST, Huang DP, Hui AB, Lo KW, Ko CW, Tsang YS, Wong N, Whitney BM, Lee JC.

Int J Cancer. 1999 Sep 24;83(1):121-6.


Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation.

Hui AB, Lo KW, Leung SF, Teo P, Fung MK, To KF, Wong N, Choi PH, Lee JC, Huang DP.

Int J Cancer. 1999 Aug 12;82(4):498-503.


Molecular genetic analysis of non-astrocytic gliomas.

Tong CY, Ng HK, Pang JC, Hui AB, Ko HC, Lee JC.

Histopathology. 1999 Apr;34(4):331-41.


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