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Items: 28

1.

Immune Pharmacodynamic Responses of the Novel Cancer Immunotherapeutic Imprime PGG in Healthy Volunteers.

Bose N, Ottoson NR, Qiu X, Harrison B, Lowe JR, Uhlik MT, Rathmann BT, Kangas TO, Jordan LR, Ertelt KE, Jonas AB, Walsh RM, Chan ASH, Fulton RB, Leonardo SM, Fraser KA, Gorden KB, Matson MA, Graff JR, Huhn RD.

J Immunol. 2019 May 15;202(10):2945-2956. doi: 10.4049/jimmunol.1801533. Epub 2019 Apr 15.

PMID:
30988115
2.

A randomized, controlled trial evaluating the efficacy and safety of BTH1677 in combination with bevacizumab, carboplatin, and paclitaxel in first-line treatment of advanced non-small cell lung cancer.

Engel-Riedel W, Lowe J, Mattson P, Richard Trout J, Huhn RD, Gargano M, Patchen ML, Walsh R, Trinh MM, Dupuis M, Schneller F.

J Immunother Cancer. 2018 Feb 27;6(1):16. doi: 10.1186/s40425-018-0324-z.

3.

Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers.

Westwood JA, Matthews GM, Shortt J, Faulkner D, Pegram HJ, Duong CP, Chesi M, Bergsagel PL, Sharp LL, Huhn RD, Darcy PK, Johnstone RW, Kershaw MH.

Leuk Res. 2014 Aug;38(8):948-54. doi: 10.1016/j.leukres.2014.05.010. Epub 2014 Jun 2.

PMID:
24934848
4.

CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans.

Beatty GL, Chiorean EG, Fishman MP, Saboury B, Teitelbaum UR, Sun W, Huhn RD, Song W, Li D, Sharp LL, Torigian DA, O'Dwyer PJ, Vonderheide RH.

Science. 2011 Mar 25;331(6024):1612-6. doi: 10.1126/science.1198443.

5.

Immune modulation with weekly dosing of an agonist CD40 antibody in a phase I study of patients with advanced solid tumors.

RĂ¼ter J, Antonia SJ, Burris HA, Huhn RD, Vonderheide RH.

Cancer Biol Ther. 2010 Nov 15;10(10):983-93. doi: 10.4161/cbt.10.10.13251. Epub 2010 Nov 15.

6.

Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody.

Vonderheide RH, Flaherty KT, Khalil M, Stumacher MS, Bajor DL, Hutnick NA, Sullivan P, Mahany JJ, Gallagher M, Kramer A, Green SJ, O'Dwyer PJ, Running KL, Huhn RD, Antonia SJ.

J Clin Oncol. 2007 Mar 1;25(7):876-83.

PMID:
17327609
7.

High-dose cyclophosphamide with autologous lymphocyte-depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia.

Huhn RD, Fogarty PF, Nakamura R, Read EJ, Leitman SF, Rick ME, Kimball J, Greene A, Hansmann K, Gratwohl A, Young N, Barrett AJ, Dunbar CE.

Blood. 2003 Jan 1;101(1):71-7. Epub 2002 Aug 8.

PMID:
12393623
8.

Umbilical cord blood stem cell transplantation and banking.

Huhn RD.

N J Med. 2000 Sep;97(9):53-7. No abstract available.

PMID:
11011553
9.

Retroviral marking and transplantation of rhesus hematopoietic cells by nonmyeloablative conditioning.

Huhn RD, Tisdale JF, Agricola B, Metzger ME, Donahue RE, Dunbar CE.

Hum Gene Ther. 1999 Jul 20;10(11):1783-90.

PMID:
10446918
10.

Effects of single intravenous doses of recombinant human interleukin-10 on subsets of circulating leukocytes in humans.

Huhn RD, Pennline K, Radwanski E, Clarke L, Sabo R, Cutler DL.

Immunopharmacology. 1999 Feb;41(2):109-17.

PMID:
10102792
11.

Effect of montelukast on single-dose theophylline pharmacokinetics.

Malmstrom K, Schwartz J, Reiss TF, Sullivan TJ, Reese JH, Jauregui L, Miller K, Scott M, Shingo S, Peszek I, Larson P, Ebel D, Hunt TL, Huhn RD, Bachmann K.

Am J Ther. 1998 May;5(3):189-95.

PMID:
10099058
12.

Pharmacokinetics and leukocyte responses of recombinant human interleukin-10.

Radwanski E, Chakraborty A, Van Wart S, Huhn RD, Cutler DL, Affrime MB, Jusko WJ.

Pharm Res. 1998 Dec;15(12):1895-901.

PMID:
9892475
13.

Images in clinical medicine. Staphylococcal psoas abscess.

Huhn RD, Dave HP.

N Engl J Med. 1998 Aug 20;339(8):519. No abstract available.

14.

Leukocytosis in response to exogenous gonadotrophin stimulation.

Hock DL, Huhn RD, Kemmann E.

Hum Reprod. 1997 Oct;12(10):2143-6.

PMID:
9402270
15.

Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers.

Huhn RD, Radwanski E, Gallo J, Affrime MB, Sabo R, Gonyo G, Monge A, Cutler DL.

Clin Pharmacol Ther. 1997 Aug;62(2):171-80.

PMID:
9284853
17.

Recombinant human interleukin-3 (rhIL-3) enhances the mobilization of peripheral blood progenitor cells by recombinant human granulocyte colony-stimulating factor (rhG-CSF) in normal volunteers.

Huhn RD, Yurkow EJ, Tushinski R, Clarke L, Sturgill MG, Hoffman R, Sheay W, Cody R, Philipp C, Resta D, George M.

Exp Hematol. 1996 Jun;24(7):839-47.

PMID:
8647235
18.

Pharmacokinetics and immunomodulatory properties of intravenously administered recombinant human interleukin-10 in healthy volunteers.

Huhn RD, Radwanski E, O'Connell SM, Sturgill MG, Clarke L, Cody RP, Affrime MB, Cutler DL.

Blood. 1996 Jan 15;87(2):699-705.

PMID:
8555493
19.

Concurrent presentation of erythrocytic and megakaryocytic aplasia.

Canavan BF, Huhn RD, Kim HC, Kosmin M, Sheay W, Saidi P.

Am J Hematol. 1996 Jan;51(1):68-72.

20.

Pharmacodynamics of daily subcutaneous recombinant human interleukin-3 in normal volunteers.

Huhn RD, Yurkow EJ, Kuhn JG, Clarke L, Gunn H, Resta D, Shah R, Myers LA, Seibold JR.

Clin Pharmacol Ther. 1995 Jan;57(1):32-41.

PMID:
7828379
21.

Evaluation of granulocyte-macrophage colony-stimulating factor for treatment of pancytopenia in children with fanconi anemia.

Guinan EC, Lopez KD, Huhn RD, Felser JM, Nathan DG.

J Pediatr. 1994 Jan;124(1):144-50.

PMID:
8283365
22.

Lime disease.

Huhn RD.

Ann Intern Med. 1991 Sep 15;115(6):500. No abstract available.

PMID:
1872508
23.

Therapeutic effects and pharmacokinetics of recombinant human granulocyte-macrophage colony-stimulating factor in childhood cancer patients receiving myelosuppressive chemotherapy.

Furman WL, Fairclough DL, Huhn RD, Pratt CB, Stute N, Petros WP, Evans WE, Bowman LC, Douglass EC, Santana VM, et al.

J Clin Oncol. 1991 Jun;9(6):1022-8.

PMID:
2033415
24.

Effects of 1 alpha, 25-dihydroxyvitamin D3 on the human chronic myelogenous leukemia cell line RWLeu-4.

Lasky SR, Bell W, Huhn RD, Posner MR, Wiemann M, Calabresi P, Eil C.

Cancer Res. 1990 May 15;50(10):3087-94.

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Studies on Limulus amoebocyte lysate II. Purification of the coagulogen and the mechanism of clotting.

Tai JY, Seid RC Jr, Huhn RD, Liu TY.

J Biol Chem. 1977 Jul 25;252(14):4773-6.

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