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Items: 1 to 50 of 85

1.

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.

Brazel DM, Jiang Y, Hughey JM, Turcot V, Zhan X, Gong J, Batini C, Weissenkampen JD, Liu M; CHD Exome+ Consortium; Consortium for Genetics of Smoking Behaviour, Barnes DR, Bertelsen S, Chou YL, Erzurumluoglu AM, Faul JD, Haessler J, Hammerschlag AR, Hsu C, Kapoor M, Lai D, Le N, de Leeuw CA, Loukola A, Mangino M, Melbourne CA, Pistis G, Qaiser B, Rohde R, Shao Y, Stringham H, Wetherill L, Zhao W, Agrawal A, Bierut L, Chen C, Eaton CB, Goate A, Haiman C, Heath A, Iacono WG, Martin NG, Polderman TJ, Reiner A, Rice J, Schlessinger D, Scholte HS, Smith JA, Tardif JC, Tindle HA, van der Leij AR, Boehnke M, Chang-Claude J, Cucca F, David SP, Foroud T, Howson JMM, Kardia SLR, Kooperberg C, Laakso M, Lettre G, Madden P, McGue M, North K, Posthuma D, Spector T, Stram D, Tobin MD, Weir DR, Kaprio J, Abecasis GR, Liu DJ, Vrieze S.

Biol Psychiatry. 2018 Dec 6. pii: S0006-3223(18)32056-0. doi: 10.1016/j.biopsych.2018.11.024. [Epub ahead of print]

PMID:
30679032
2.

Mediterranean Lithophyllum stictiforme (Corallinales, Rhodophyta) is a genetically diverse species complex: implications for species circumscription, biogeography and conservation of coralligenous habitats.

Pezzolesi L, Peña V, Le Gall L, Gabrielson PW, Kaleb S, Hughey JR, Rodondi G, Hernandez-Kantun JJ, Falace A, Basso D, Cerrano C, Rindi F.

J Phycol. 2019 Jan 18. doi: 10.1111/jpy.12837. [Epub ahead of print]

PMID:
30657167
3.

LimoRhyde: A Flexible Approach for Differential Analysis of Rhythmic Transcriptome Data.

Singer JM, Hughey JJ.

J Biol Rhythms. 2018 Nov 25:748730418813785. doi: 10.1177/0748730418813785. [Epub ahead of print]

PMID:
30472909
4.

Combinatorial processing of bacterial and host-derived innate immune stimuli at the single-cell level.

Gutschow MV, Mason JC, Lane KM, Maayan I, Hughey JJ, Bajar BT, Amatya DN, Valle SD, Covert MW.

Mol Biol Cell. 2019 Jan 15;30(2):282-292. doi: 10.1091/mbc.E18-07-0423. Epub 2018 Nov 21.

PMID:
30462580
5.

Population-level rhythms in human skin with implications for circadian medicine.

Wu G, Ruben MD, Schmidt RE, Francey LJ, Smith DF, Anafi RC, Hughey JJ, Tasseff R, Sherrill JD, Oblong JE, Mills KJ, Hogenesch JB.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12313-12318. doi: 10.1073/pnas.1809442115. Epub 2018 Oct 30.

PMID:
30377266
6.
7.

Pulling the covers in electronic health records for an association study with self-reported sleep behaviors.

Rhoades SD, Bastarache L, Denny JC, Hughey JJ.

Chronobiol Int. 2018 Nov;35(12):1702-1712. doi: 10.1080/07420528.2018.1508152. Epub 2018 Sep 5.

8.

MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data.

Hu Z, Jujjavarapu C, Hughey JJ, Andorf S, Lee HC, Gherardini PF, Spitzer MH, Thomas CG, Campbell J, Dunn P, Wiser J, Kidd BA, Dudley JT, Nolan GP, Bhattacharya S, Butte AJ.

Cell Rep. 2018 Jul 31;24(5):1377-1388. doi: 10.1016/j.celrep.2018.07.003.

9.

Genomics reveals abundant speciation in the coral reef building alga Porolithon onkodes (Corallinales, Rhodophyta).

Gabrielson PW, Hughey JR, Diaz-Pulido G.

J Phycol. 2018 Aug;54(4):429-434. doi: 10.1111/jpy.12761.

PMID:
29920669
10.

Tau-independent Phase Analysis: A Novel Method for Accurately Determining Phase Shifts.

Tackenberg MC, Jones JR, Page TL, Hughey JJ.

J Biol Rhythms. 2018 Jun;33(3):223-232. doi: 10.1177/0748730418768116. Epub 2018 Apr 11.

11.

Phenotype risk scores identify patients with unrecognized Mendelian disease patterns.

Bastarache L, Hughey JJ, Hebbring S, Marlo J, Zhao W, Ho WT, Van Driest SL, McGregor TL, Mosley JD, Wells QS, Temple M, Ramirez AH, Carroll R, Osterman T, Edwards T, Ruderfer D, Velez Edwards DR, Hamid R, Cogan J, Glazer A, Wei WQ, Feng Q, Brilliant M, Zhao ZJ, Cox NJ, Roden DM, Denny JC.

Science. 2018 Mar 16;359(6381):1233-1239. doi: 10.1126/science.aal4043.

PMID:
29590070
12.

Evidence for widespread dysregulation of circadian clock progression in human cancer.

Shilts J, Chen G, Hughey JJ.

PeerJ. 2018 Jan 31;6:e4327. doi: 10.7717/peerj.4327. eCollection 2018.

13.

Live-cell measurements of kinase activity in single cells using translocation reporters.

Kudo T, Jeknić S, Macklin DN, Akhter S, Hughey JJ, Regot S, Covert MW.

Nat Protoc. 2018 Jan;13(1):155-169. doi: 10.1038/nprot.2017.128. Epub 2017 Dec 21.

PMID:
29266096
14.

Perceptions of Important Characteristics of Physical Activity Facilities: Implications for Engagement in Walking, Moderate and Vigorous Physical Activity.

Heinrich KM, Haddock CK, Jitnarin N, Hughey J, Berkel LA, Poston WSC.

Front Public Health. 2017 Nov 28;5:319. doi: 10.3389/fpubh.2017.00319. eCollection 2017.

15.

Self-reported dietary adherence, disease-specific symptoms, and quality of life are associated with healthcare provider follow-up in celiac disease.

Hughey JJ, Ray BK, Lee AR, Voorhees KN, Kelly CP, Schuppan D.

BMC Gastroenterol. 2017 Dec 11;17(1):156. doi: 10.1186/s12876-017-0713-7.

16.

Development of Itraconazole Tablets Containing Viscous KinetiSol Solid Dispersions: In Vitro and In Vivo Analysis in Dogs.

Keen JM, LaFountaine JS, Hughey JR, Miller DA, McGinity JW.

AAPS PharmSciTech. 2018 Jul;19(5):1998-2008. doi: 10.1208/s12249-017-0903-1. Epub 2017 Nov 30.

PMID:
29192405
17.

Guidelines for Genome-Scale Analysis of Biological Rhythms.

Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptáček LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB.

J Biol Rhythms. 2017 Oct;32(5):380-393. doi: 10.1177/0748730417728663. Epub 2017 Nov 3.

18.

In Vitro-In Vivo Correlations of Carbamazepine Nanodispersions for Application in Formulation Development.

Warnken Z, Puppolo M, Hughey J, Duarte I, Jansen-Varnum S.

J Pharm Sci. 2018 Jan;107(1):453-465. doi: 10.1016/j.xphs.2017.10.014. Epub 2017 Oct 16.

PMID:
29045883
19.

Genetic origins of the Minoans and Mycenaeans.

Lazaridis I, Mittnik A, Patterson N, Mallick S, Rohland N, Pfrengle S, Furtwängler A, Peltzer A, Posth C, Vasilakis A, McGeorge PJP, Konsolaki-Yannopoulou E, Korres G, Martlew H, Michalodimitrakis M, Özsait M, Özsait N, Papathanasiou A, Richards M, Roodenberg SA, Tzedakis Y, Arnott R, Fernandes DM, Hughey JR, Lotakis DM, Navas PA, Maniatis Y, Stamatoyannopoulos JA, Stewardson K, Stockhammer P, Pinhasi R, Reich D, Krause J, Stamatoyannopoulos G.

Nature. 2017 Aug 10;548(7666):214-218. doi: 10.1038/nature23310. Epub 2017 Aug 2.

20.

Biomechanical Comparison Between the Cruciate Suture and a Single Vertical Suture Used for Arthroscopic Meniscal Repair: Response.

Milchteim C, Branch EA, Maughon T, Hughey J, Anz AW.

Orthop J Sports Med. 2017 Jun 30;5(6):2325967117710176. doi: 10.1177/2325967117710176. eCollection 2017 Jun. No abstract available.

21.

The coralline genera Sporolithon and Heydrichia (Sporolithales, Rhodophyta) clarified by sequencing type material of their generitypes and other species.

Richards JL, Sauvage T, Schmidt WE, Fredericq S, Hughey JR, Gabrielson PW.

J Phycol. 2017 Oct;53(5):1044-1059. doi: 10.1111/jpy.12562. Epub 2017 Aug 7.

PMID:
28681431
22.

Biomimetic Dissolution: A Tool to Predict Amorphous Solid Dispersion Performance.

Puppolo MM, Hughey JR, Dillon T, Storey D, Jansen-Varnum S.

AAPS PharmSciTech. 2017 Nov;18(8):2841-2853. doi: 10.1208/s12249-017-0783-4. Epub 2017 May 30.

PMID:
28560506
23.

Machine learning identifies a compact gene set for monitoring the circadian clock in human blood.

Hughey JJ.

Genome Med. 2017 Feb 28;9(1):19. doi: 10.1186/s13073-017-0406-4.

24.

Analysis of the complete plastomes of three species of Membranoptera (Ceramiales, Rhodophyta) from Pacific North America.

Hughey JR, Hommersand MH, Gabrielson PW, Miller KA, Fuller T.

J Phycol. 2017 Feb;53(1):32-43. doi: 10.1111/jpy.12472. Epub 2016 Nov 2.

PMID:
27690326
25.

Mitogenomes from type specimens, a genotyping tool for morphologically simple species: ten genomes of agar-producing red algae.

Boo GH, Hughey JR, Miller KA, Boo SM.

Sci Rep. 2016 Oct 14;6:35337. doi: 10.1038/srep35337.

26.

Differential Phasing between Circadian Clocks in the Brain and Peripheral Organs in Humans.

Hughey JJ, Butte AJ.

J Biol Rhythms. 2016 Dec;31(6):588-597. doi: 10.1177/0748730416668049. Epub 2016 Oct 4.

27.

Biomechanical Comparison of Parallel and Crossed Suture Repair for Longitudinal Meniscus Tears.

Milchteim C, Branch EA, Maughon T, Hughey J, Anz AW.

Orthop J Sports Med. 2016 Apr 8;4(4):2325967116640263. doi: 10.1177/2325967116640263. eCollection 2016 Apr.

28.

Is the crowd better as an assistant or a replacement in ontology engineering? An exploration through the lens of the Gene Ontology.

Mortensen JM, Telis N, Hughey JJ, Fan-Minogue H, Van Auken K, Dumontier M, Musen MA.

J Biomed Inform. 2016 Apr;60:199-209. doi: 10.1016/j.jbi.2016.02.005. Epub 2016 Feb 10.

29.

Complete Genome Sequence of Nonhemolytic Streptococcus agalactiae Serotype V Strain 1, Isolated from the Buccal Cavity of a Canine.

Harden LK, Morales KM, Hughey JR.

Genome Announc. 2016 Jan 28;4(1). pii: e01612-15. doi: 10.1128/genomeA.01612-15.

30.

ZeitZeiger: supervised learning for high-dimensional data from an oscillatory system.

Hughey JJ, Hastie T, Butte AJ.

Nucleic Acids Res. 2016 May 5;44(8):e80. doi: 10.1093/nar/gkw030. Epub 2016 Jan 26.

31.

Four new species of Pyropia (Bangiales, Rhodophyta) from the west coast of North America: the Pyropialanceolata species complex updated.

Lindstrom SC, Hughey JR, Rosas LE.

PhytoKeys. 2015 Jun 25;(52):1-22. doi: 10.3897/phytokeys.52.5009. eCollection 2015.

32.

Identification of a new marine algal species Pyropia nitida sp. nov. (Bangiales: Rhodophyta) from Monterey, California.

Harden LK, Morales KM, Hughey JR.

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Jul;27(4):3058-62. doi: 10.3109/19401736.2015.1063137. Epub 2015 Jul 8.

PMID:
26153737
33.

Continuous twin screw melt granulation of glyceryl behenate: Development of controlled release tramadol hydrochloride tablets for improved safety.

Keen JM, Foley CJ, Hughey JR, Bennett RC, Jannin V, Rosiaux Y, Marchaud D, McGinity JW.

Int J Pharm. 2015 Jun 20;487(1-2):72-80. doi: 10.1016/j.ijpharm.2015.03.058. Epub 2015 Mar 31.

PMID:
25839417
34.

Robust meta-analysis of gene expression using the elastic net.

Hughey JJ, Butte AJ.

Nucleic Acids Res. 2015 Jul 13;43(12):e79. doi: 10.1093/nar/gkv229. Epub 2015 Mar 31.

35.

Neighborhood environment perceptions and the likelihood of smoking and alcohol use.

Jitnarin N, Heinrich KM, Haddock CK, Hughey J, Berkel L, Poston WS.

Int J Environ Res Public Health. 2015 Jan 14;12(1):784-99. doi: 10.3390/ijerph120100784.

36.

Single-cell variation leads to population invariance in NF-κB signaling dynamics.

Hughey JJ, Gutschow MV, Bajar BT, Covert MW.

Mol Biol Cell. 2015 Feb 1;26(3):583-90. doi: 10.1091/mbc.E14-08-1267. Epub 2014 Dec 3.

37.

Effect of tablet structure on controlled release from supersaturating solid dispersions containing glyceryl behenate.

Keen JM, Hughey JR, Bennett RC, Jannin V, Rosiaux Y, Marchaud D, McGinity JW.

Mol Pharm. 2015 Jan 5;12(1):120-6. doi: 10.1021/mp500480y. Epub 2014 Nov 25.

PMID:
25347621
38.

The incorporation of low-substituted hydroxypropyl cellulose into solid dispersion systems.

Hughey JR, Keen JM, Bennett RC, Obara S, McGinity JW.

Drug Dev Ind Pharm. 2015;41(8):1294-301. doi: 10.3109/03639045.2014.947508. Epub 2014 Aug 18.

PMID:
25133663
39.

High-sensitivity measurements of multiple kinase activities in live single cells.

Regot S, Hughey JJ, Bajar BT, Carrasco S, Covert MW.

Cell. 2014 Jun 19;157(7):1724-34. doi: 10.1016/j.cell.2014.04.039.

40.

Complete mitochondrial genome of the holotype specimen of Wildemania schizophylla (Bangiales: Rhodophyta).

Silva MY, Hughey JR.

Mitochondrial DNA A DNA Mapp Seq Anal. 2016;27(2):1001-2. doi: 10.3109/19401736.2014.926524. Epub 2014 Jun 18.

PMID:
24938105
41.

Minimally destructive sampling of type specimens of Pyropia (Bangiales, Rhodophyta) recovers complete plastid and mitochondrial genomes.

Hughey JR, Gabrielson PW, Rohmer L, Tortolani J, Silva M, Miller KA, Young JD, Martell C, Ruediger E.

Sci Rep. 2014 Jun 4;4:5113. doi: 10.1038/srep05113.

42.

The microfluidic multitrap nanophysiometer for hematologic cancer cell characterization reveals temporal sensitivity of the calcein-AM efflux assay.

Byrd TF 4th, Hoang LT, Kim EG, Pfister ME, Werner EM, Arndt SE, Chamberlain JW, Hughey JJ, Nguyen BA, Schneibel EJ, Wertz LL, Whitfield JS, Wikswo JP, Seale KT.

Sci Rep. 2014 May 30;4:5117. doi: 10.1038/srep05117.

43.

Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract.

Bennett RC, Brough C, Miller DA, O'Donnell KP, Keen JM, Hughey JR, Williams RO 3rd, McGinity JW.

Drug Dev Ind Pharm. 2015 Mar;41(3):382-97. doi: 10.3109/03639045.2013.866142. Epub 2013 Dec 16.

PMID:
24329130
44.

A European population in Minoan Bronze Age Crete.

Hughey JR, Paschou P, Drineas P, Mastropaolo D, Lotakis DM, Navas PA, Michalodimitrakis M, Stamatoyannopoulos JA, Stamatoyannopoulos G.

Nat Commun. 2013;4:1861. doi: 10.1038/ncomms2871.

45.

The use of inorganic salts to improve the dissolution characteristics of tablets containing Soluplus®-based solid dispersions.

Hughey JR, Keen JM, Miller DA, Kolter K, Langley N, McGinity JW.

Eur J Pharm Sci. 2013 Mar 12;48(4-5):758-66. doi: 10.1016/j.ejps.2013.01.004. Epub 2013 Jan 21.

PMID:
23348153
46.

Single-cell and population NF-κB dynamic responses depend on lipopolysaccharide preparation.

Gutschow MV, Hughey JJ, Ruggero NA, Bajar BT, Valle SD, Covert MW.

PLoS One. 2013;8(1):e53222. doi: 10.1371/journal.pone.0053222. Epub 2013 Jan 3.

47.

Preparation and characterization of fusion processed solid dispersions containing a viscous thermally labile polymeric carrier.

Hughey JR, Keen JM, Miller DA, Brough C, McGinity JW.

Int J Pharm. 2012 Nov 15;438(1-2):11-9. doi: 10.1016/j.ijpharm.2012.08.032. Epub 2012 Aug 31.

PMID:
22960321
48.

A search for β thalassemia mutations in 4000 year old ancient DNAs of Minoan Cretans.

Hughey JR, Du M, Li Q, Michalodimitrakis M, Stamatoyannopoulos G.

Blood Cells Mol Dis. 2012 Jan 15;48(1):7-10. doi: 10.1016/j.bcmd.2011.09.006. Epub 2011 Oct 14.

49.

Thermal processing of a poorly water-soluble drug substance exhibiting a high melting point: the utility of KinetiSol® Dispersing.

Hughey JR, Keen JM, Brough C, Saeger S, McGinity JW.

Int J Pharm. 2011 Oct 31;419(1-2):222-30. doi: 10.1016/j.ijpharm.2011.08.007. Epub 2011 Aug 16.

PMID:
21864663
50.

Use of highly compressible Ceolus™ microcrystalline cellulose for improved dosage form properties containing a hydrophilic solid dispersion.

Dinunzio JC, Schilling SU, Coney AW, Hughey JR, Kaneko N, McGinity JW.

Drug Dev Ind Pharm. 2012 Feb;38(2):180-9. doi: 10.3109/03639045.2011.595415. Epub 2011 Jul 21.

PMID:
21774741

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