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DPP1 Inhibitors: Exploring the Role of Water in the S2 Pocket of DPP1 with Substituted Pyrrolidines.

Käck H, Doyle K, Hughes SJ, Bodnarchuk MS, Lönn H, Van De Poël A, Palmer N.

ACS Med Chem Lett. 2019 Jul 15;10(8):1222-1227. doi: 10.1021/acsmedchemlett.9b00261. eCollection 2019 Aug 8.


Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome.

Witztum JL, Gaudet D, Freedman SD, Alexander VJ, Digenio A, Williams KR, Yang Q, Hughes SG, Geary RS, Arca M, Stroes ESG, Bergeron J, Soran H, Civeira F, Hemphill L, Tsimikas S, Blom DJ, O'Dea L, Bruckert E.

N Engl J Med. 2019 Aug 8;381(6):531-542. doi: 10.1056/NEJMoa1715944.


Clonal expansion of CAR T cells harboring lentivector integration in the CBL gene following anti-CD22 CAR T-cell therapy.

Shah NN, Qin H, Yates B, Su L, Shalabi H, Raffeld M, Ahlman MA, Stetler-Stevenson M, Yuan C, Guo S, Liu S, Hughes SH, Fry TJ, Wu X.

Blood Adv. 2019 Aug 13;3(15):2317-2322. doi: 10.1182/bloodadvances.2019000219. No abstract available.


Child weight status and accuracy of perceived child weight status as predictors of Latina mothers' feeding practices and styles.

Hidalgo-Mendez J, Power TG, Fisher JO, O'Connor TM, Hughes SO.

Appetite. 2019 Jul 29;142:104387. doi: 10.1016/j.appet.2019.104387. [Epub ahead of print]


Letter to the editor: Measles outbreak in Gothenburg urban area, Sweden, 2017 to 2018: low viral load in breakthrough infections.

Bolotin S, Crowcroft NS, Hughes SL, De Serres G.

Euro Surveill. 2019 Jul;24(30). doi: 10.2807/1560-7917.ES.2019.24.30.1900465. No abstract available.


HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy.

McManus WR, Bale MJ, Spindler J, Wiegand A, Musick A, Patro SC, Sobolewski MD, Musick VK, Anderson EM, Cyktor JC, Halvas EK, Shao W, Wells D, Wu X, Keele BF, Milush JM, Hoh R, Mellors JW, Hughes SH, Deeks SG, Coffin JM, Kearney MF.

J Clin Invest. 2019 Jul 30;130. pii: 126714. doi: 10.1172/JCI126714.


Barriers and Facilitators to Cochlear Implant Uptake in Australia and the United Kingdom.

Bierbaum M, McMahon CM, Hughes S, Boisvert I, Lau AYS, Braithwaite J, Rapport F.

Ear Hear. 2019 Jul 24. doi: 10.1097/AUD.0000000000000762. [Epub ahead of print]


A genome-wide screen identifies IRF2 as a key regulator of caspase-4 in human cells.

Benaoudia S, Martin A, Puig Gamez M, Gay G, Lagrange B, Cornut M, Krasnykov K, Claude JB, Bourgeois CF, Hughes S, Gillet B, Allatif O, Corbin A, Ricci R, Henry T.

EMBO Rep. 2019 Jul 29:e48235. doi: 10.15252/embr.201948235. [Epub ahead of print]


Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.

Cain JT, Likhite S, White KA, Timm DJ, Davis SS, Johnson TB, Dennys-Rivers CN, Rinaldi F, Motti D, Corcoran S, Morales P, Pierson C, Hughes SM, Lee SY, Kaspar BK, Meyer K, Weimer JM.

Mol Ther. 2019 Jul 10. pii: S1525-0016(19)30311-9. doi: 10.1016/j.ymthe.2019.06.015. [Epub ahead of print]


N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels.

Alexander VJ, Xia S, Hurh E, Hughes SG, O'Dea L, Geary RS, Witztum JL, Tsimikas S.

Eur Heart J. 2019 Apr 24. pii: ehz209. doi: 10.1093/eurheartj/ehz209. [Epub ahead of print]


Earlier Palliative Care Referrals Associated with Reduced Length of Stay and Hospital Charges.

Macmillan PJ, Chalfin B, Soleimani Fard A, Hughes S.

J Palliat Med. 2019 Jul 19. doi: 10.1089/jpm.2019.0029. [Epub ahead of print]


Toward Accurate Extraction of Respiratory Frequency From the Photoplethysmogram: Effect of Measurement Site.

Hartmann V, Liu H, Chen F, Hong W, Hughes S, Zheng D.

Front Physiol. 2019 Jun 18;10:732. doi: 10.3389/fphys.2019.00732. eCollection 2019.


A pro-inflammatory CD8+ T-cell subset patrols the cervicovaginal tract.

Pattacini L, Woodward Davis A, Czartoski J, Mair F, Presnell S, Hughes SM, Hyrien O, Lentz GM, Kirby AC, Fialkow MF, Hladik F, Prlic M, Lund JM.

Mucosal Immunol. 2019 Jul 16. doi: 10.1038/s41385-019-0186-9. [Epub ahead of print]


Clinical Presentation of Influenza in Children 6 to 35 Months of Age: Findings From a Randomized Clinical Trial of Inactivated Quadrivalent Influenza Vaccine.

Danier J, Rivera L, Claeys C, Dbaibo G, Jain VK, Kosalaraksa P, Woo W, Yanni E, Zaman K, Acosta B, Amanullah A, Ariza M, Luisa Arroba Basanta M, Bavdekar A, Carmona A, Cousin L, Diaz A, Diez-Domingo J, Cagri Dinleyici E, Faust SN, Garcia-Sicilia J, Gomez-Go GD, Antionette Gonzales L, Hacimustafaoglu M, Hughes SM, Izu A, Jackowska T, Kant S, Lucero M, Mares Bermudez J, Martinón-Torres F, Montellano M, Prymula R, Puthanakit T, Ruzkova R, Sadowska-Krawczenko I, Soni J, Szymanski H, Ulied A, Schuind A, Innis BL; Flu4VEC Study Group.

Pediatr Infect Dis J. 2019 Aug;38(8):866-872. doi: 10.1097/INF.0000000000002387.


2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks.

Merg AD, Touponse G, van Genderen E, Zuo X, Bazrafshan A, Blum T, Hughes S, Salaita K, Abrahams JP, Conticello VP.

Angew Chem Int Ed Engl. 2019 Jul 10. doi: 10.1002/anie.201906214. [Epub ahead of print] Review.


Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans.

Ferris AL, Wells DW, Guo S, Del Prete GQ, Swanstrom AE, Coffin JM, Wu X, Lifson JD, Hughes SH.

PLoS Pathog. 2019 Jul 10;15(7):e1007869. doi: 10.1371/journal.ppat.1007869. eCollection 2019 Jul.


Study protocol for the validation of a new patient-reported outcome measure (PROM) of listening effort in cochlear implantation: the Listening Effort Questionnaire-Cochlear Implant (LEQ-CI).

Hughes SE, Rapport F, Watkins A, Boisvert I, McMahon CM, Hutchings HA.

BMJ Open. 2019 Jul 9;9(7):e028881. doi: 10.1136/bmjopen-2018-028881.


Quantization of Quasinormal Modes for Open Cavities and Plasmonic Cavity Quantum Electrodynamics.

Franke S, Hughes S, Dezfouli MK, Kristensen PT, Busch K, Knorr A, Richter M.

Phys Rev Lett. 2019 May 31;122(21):213901. doi: 10.1103/PhysRevLett.122.213901.


Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs.

Hughes SA, Wang F, Wang S, Kreutzberger MAB, Osinski T, Orlova A, Wall JS, Zuo X, Egelman EH, Conticello VP.

Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14456-14464. doi: 10.1073/pnas.1903910116. Epub 2019 Jul 1.


Early identification of severe community-acquired pneumonia: a retrospective observational study.

Grudzinska FS, Aldridge K, Hughes S, Nightingale P, Parekh D, Bangash M, Dancer R, Patel J, Sapey E, Thickett DR, Dosanjh DP.

BMJ Open Respir Res. 2019 Jun 5;6(1):e000438. doi: 10.1136/bmjresp-2019-000438. eCollection 2019.


The experiences of family members witnessing the diminishing drinking of a dying relative: An adapted meta-narrative literature review.

Pettifer A, Froggatt K, Hughes S.

Palliat Med. 2019 Jul 1:269216319859728. doi: 10.1177/0269216319859728. [Epub ahead of print]


Cognitive-motor exergaming for reducing fall risk in people with chronic stroke: A randomized controlled trial.

Kannan L, Vora J, Bhatt T, Hughes SL.

NeuroRehabilitation. 2019;44(4):493-510. doi: 10.3233/NRE-182683.


EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype.

Ciano M, Mantellato G, Connolly M, Paul-Clark M, Willis-Owen S, Moffatt MF, Cookson WOCM, Mitchell JA, Polkey MI, Hughes SM, Kemp PR, Natanek SA.

Sci Rep. 2019 Jun 25;9(1):9218. doi: 10.1038/s41598-019-45567-4.


Clones of infected cells arise early in HIV-infected individuals.

Coffin JM, Wells DW, Zerbato JM, Kuruc JD, Guo S, Luke BT, Eron JJ, Bale M, Spindler J, Simonetti FR, Hill S, Kearney MF, Maldarelli F, Wu X, Mellors JW, Hughes SH.

JCI Insight. 2019 Jun 20;4(12). pii: 128432. doi: 10.1172/jci.insight.128432. eCollection 2019 Jun 20.


HIV pre-exposure prophylaxis and the 'problems' of reduced condom use and sexually transmitted infections in Australia: a critical analysis from an evidence-making intervention perspective.

Holt M, Newman CE, Lancaster K, Smith AK, Hughes S, Truong HM.

Sociol Health Illn. 2019 Jun 18. doi: 10.1111/1467-9566.12967. [Epub ahead of print]


NICE guidelines on prostate cancer 2019.

Dasgupta P, Davis J, Hughes S.

BJU Int. 2019 Jul;124(1):1. doi: 10.1111/bju.14815. No abstract available.


A C-terminal peptide from secreted amyloid precursor protein-α enhances long-term potentiation in rats and a transgenic mouse model of Alzheimer's disease.

Morrissey JA, Mockett BG, Singh A, Kweon D, Ohline SM, Tate WP, Hughes SM, Abraham WC.

Neuropharmacology. 2019 Oct;157:107670. doi: 10.1016/j.neuropharm.2019.107670. Epub 2019 Jun 13.


Diffusion tensor imaging reveals changes in microstructural integrity along compressed nerve roots that correlate with chronic pain symptoms and motor deficiencies in elderly stenosis patients.

Hughes SW, Hellyer PJ, Sharp DJ, Newbould RD, Patel MC, Strutton PH.

Neuroimage Clin. 2019 May 28;23:101880. doi: 10.1016/j.nicl.2019.101880. [Epub ahead of print]


Stroop-like effects of derived stimulus-stimulus relations.

Liefooghe B, Hughes S, Schmidt JR, De Houwer J.

J Exp Psychol Learn Mem Cogn. 2019 Jun 13. doi: 10.1037/xlm0000724. [Epub ahead of print]


A Collaborative Approach: Care Staff and Families Working Together to Safeguard the Quality of Life of Residents Living With Advanced Dementia.

Hughes SE, Woods B, Algar-Skaife K, Jelley H, Jones CH.

J Cent Nerv Syst Dis. 2019 May 13;11:1179573519843872. doi: 10.1177/1179573519843872. eCollection 2019.


Goal setting in group programmes for long-term condition self-management support: experiences of patients and healthcare professionals.

Hughes S, Lewis S, Willis K, Rogers A, Wyke S, Smith L.

Psychol Health. 2019 Jun 12:1-17. doi: 10.1080/08870446.2019.1623891. [Epub ahead of print]


Assessment of population immunity to measles in Ontario, Canada: a Canadian Immunization Research Network (CIRN) study.

Bolotin S, Severini A, Hatchette T, McLachlan E, Savage R, Hughes SL, Wang J, Deeks SL, Wilson S, Brisson M, Halperin SA, Gubbay J, Mazzulli T, Serhir B, Ward BJ, Crowcroft N.

Hum Vaccin Immunother. 2019 Jul 16:1-9. doi: 10.1080/21645515.2019.1619402. [Epub ahead of print]


Large-scale cultivation of Caenorhabditis elegans in a bioreactor using a labor-friendly fed-batch approach.

Heshof R, Visscher B, Prömel S, Hughes S.

Biotechniques. 2019 Jul;67(1):33-39. doi: 10.2144/btn-2019-0008. Epub 2019 Jun 11.


Building a successful geriatric oncology research program: Lessons learned from Dr. Arti Hurria's cancer and aging research team.

Katheria V, Lee T, Charles K, Roberts E, Vazquez J, Hughes SFDS, Chien L, Uranga C, Sun CL, Kim H, Morrison R.

J Geriatr Oncol. 2019 Jun 3. pii: S1879-4068(19)30165-1. doi: 10.1016/j.jgo.2019.05.015. [Epub ahead of print] No abstract available.


The association of TV viewing during dinner meals with quality of dietary intake and BMI z-scores among low income, ethnic minority preschool children.

O'Connor TM, Elias C, Thompson RR, Arlinghaus KR, Vollrath K, Hernandez DC, Power TG, Hughes SO.

Appetite. 2019 Sep 1;140:231-238. doi: 10.1016/j.appet.2019.05.023. Epub 2019 May 20.


The E3 ubiquitin ligase Sina regulates the assembly and disassembly of the synaptonemal complex in Drosophila females.

Hughes SE, Hemenway E, Guo F, Yi K, Yu Z, Hawley RS.

PLoS Genet. 2019 May 20;15(5):e1008161. doi: 10.1371/journal.pgen.1008161. eCollection 2019 May.


Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish.

Kague E, Hughes SM, Lawrence EA, Cross S, Martin-Silverstone E, Hammond CL, Hinits Y.

FASEB J. 2019 Aug;33(8):9116-9130. doi: 10.1096/fj.201802654RR. Epub 2019 May 17.


Variation in toxicity and ecological risks associated with some oil sands groundwaters.

Kilgour B, Mahaffey A, Brown C, Hughes S, Hatry C, Hamilton L.

Sci Total Environ. 2019 Apr 1;659:1224-1233. doi: 10.1016/j.scitotenv.2018.12.287. Epub 2018 Dec 20.


The Proteome of Pancreatic Cancer-Derived Exosomes Reveals Signatures Rich in Key Signaling Pathways.

Han S, Huo Z, Nguyen K, Zhu F, Underwood PW, Basso KBG, George TJ, Hughes SJ.

Proteomics. 2019 Jul;19(13):e1800394. doi: 10.1002/pmic.201800394. Epub 2019 Jun 11.


Exploratory factor analysis of The Comprehensive Feeding Practices Questionnaire (CFPQ) in a low-income hispanic sample of preschool aged children.

Arlinghaus KR, Hernandez DC, Eagleton SG, Chen TA, Power TG, Hughes SO.

Appetite. 2019 Sep 1;140:82-90. doi: 10.1016/j.appet.2019.04.029. Epub 2019 May 1.


Therapist telephone-delivered CBT and web-based CBT compared with treatment as usual in refractory irritable bowel syndrome: the ACTIB three-arm RCT.

Everitt H, Landau S, Little P, Bishop FL, O'Reilly G, Sibelli A, Holland R, Hughes S, Windgassen S, McCrone P, Goldsmith K, Coleman N, Logan R, Chalder T, Moss-Morris R.

Health Technol Assess. 2019 Apr;23(17):1-154. doi: 10.3310/hta23170.


'Light in dark places': exploring qualitative data from a longitudinal study using creative arts as a form of social prescribing.

Redmond M, Sumner RC, Crone DM, Hughes S.

Arts Health. 2018 Jul 18:1-14. doi: 10.1080/17533015.2018.1490786. [Epub ahead of print]


Hearing impairment and daily-life fatigue: a qualitative study.

Holman JA, Drummond A, Hughes SE, Naylor G.

Int J Audiol. 2019 Jul;58(7):408-416. doi: 10.1080/14992027.2019.1597284. Epub 2019 Apr 28.


Attention-deficit hyperactivity disorder symptomatology, binge eating disorder symptomatology, and body mass index among college students.

Hanson JA, Phillips LN, Hughes SM, Corson K.

J Am Coll Health. 2019 Apr 22:1-7. doi: 10.1080/07448481.2019.1583651. [Epub ahead of print]


Neonatal Conjunctivitis Caused by Neisseria meningitidis US Urethritis Clade, New York, USA, August 2017.

Kretz CB, Bergeron G, Aldrich M, Bloch D, Del Rosso PE, Halse TA, Ostrowsky B, Liu Q, Gonzalez E, Omoregie E, Chicaiza L, Zayas G, Tha B, Liang A, Wang JC, Levi M, Hughes S, Musser KA, Weiss D, Rakeman JL.

Emerg Infect Dis. 2019 May;25(5):972-975. doi: 10.3201/eid2505.181631.


Trauma, Power, and Intimate Relationships Among Women in Prison.

McCauley HL, Richie F, Hughes S, Johnson JE, Zlotnick C, Rosen RK, Wechsberg WM, Kuo CC.

Violence Against Women. 2019 Apr 18:1077801219842948. doi: 10.1177/1077801219842948. [Epub ahead of print]


Blood Lead Levels Among Resettled Refugee Children in Select US States, 2010-2014.

Pezzi C, Lee D, Kennedy L, Aguirre J, Titus M, Ford R, Cochran J, Smock L, Mamo B, Urban K, Morillo J, Hughes S, Payton C, Scott K, Montour J, Matheson J, Brown MJ, Mitchell T.

Pediatrics. 2019 May;143(5). pii: e20182591. doi: 10.1542/peds.2018-2591.


Surgical outcomes for chronic exertional compartment syndrome following improved diagnostic criteria.

Simpson C, Roscoe D, Hughes S, Hulse D, Guthrie H.

J R Army Med Corps. 2019 Apr 16. pii: jramc-2019-001171. doi: 10.1136/jramc-2019-001171. [Epub ahead of print]


Home parenteral nutrition provision modalities for chronic intestinal failure in adult patients: An international survey.

Pironi L, Steiger E, Brandt C, Joly F, Wanten G, Chambrier C, Aimasso U, Sasdelli AS, Zeraschi S, Kelly D, Szczepanek K, Jukes A, Di Caro S, Theilla M, Kunecki M, Daniels J, Serlie M, Poullenot F, Wu J, Cooper SC, Rasmussen HH, Compher C, Seguy D, Crivelli A, Pagano MC, Hughes SJ, Guglielmi FW, Kozjek NR, Schneider SM, Gillanders L, Ellegard L, Thibault R, Matras P, Zmarzly A, Matysiak K, Van Gossum A, Forbes A, Wyer N, Taus M, Virgili NM, O'Callaghan M, Chapman B, Osland E, Cuerda C, Sahin P, Jones L, Won Lee AD, Masconale L, Orlandoni P, Izbéki F, Spaggiari C, Bueno M, Doitchinova-Simeonova M, Garde C, Serralde-Zúñiga AE, Olveira G, Krznaric Z, Czako L, Kekstas G, Sanz-Paris A, Jáuregui EP, Murillo AZ, Schafer E, Arends J, Suárez-Llanos JP, Lal S; Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of ESPEN; European Society for Clinical Nutrition and Metabolism.

Clin Nutr. 2019 Mar 25. pii: S0261-5614(19)30123-2. doi: 10.1016/j.clnu.2019.03.010. [Epub ahead of print]


Indoor cannabis smoke and children's health.

Posis A, Bellettiere J, Liles S, Alcaraz J, Nguyen B, Berardi V, Klepeis NE, Hughes SC, Wu T, Hovell MF.

Prev Med Rep. 2019 Mar 16;14:100853. doi: 10.1016/j.pmedr.2019.100853. eCollection 2019 Jun.

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