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Items: 49

1.

Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy.

Floros KV, Lochmann TL, Hu B, Monterrubio C, Hughes MT, Wells JD, Morales CB, Ghotra MS, Costa C, Souers AJ, Boikos SA, Leverson JD, Tan M, Serra V, Koblinski JE, Arribas J, Prat A, Paré L, Miller TW, Dozmorov MG, Harada H, Windle BE, Scaltriti M, Faber AC.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2594-E2603. doi: 10.1073/pnas.1717820115. Epub 2018 Feb 23.

2.

Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM.

Song KA, Niederst MJ, Lochmann TL, Hata AN, Kitai H, Ham J, Floros KV, Hicks MA, Hu H, Mulvey HE, Drier Y, Heisey DAR, Hughes MT, Patel NU, Lockerman EL, Garcia A, Gillepsie S, Archibald HL, Gomez-Caraballo M, Nulton TJ, Windle BE, Piotrowska Z, Sahingur SE, Taylor SM, Dozmorov M, Sequist LV, Bernstein B, Ebi H, Engelman JA, Faber AC.

Clin Cancer Res. 2018 Jan 1;24(1):197-208. doi: 10.1158/1078-0432.CCR-17-1577. Epub 2017 Oct 19.

PMID:
29051323
3.

The pharmacist and medical aid in dying.

Hughes MT.

Am J Health Syst Pharm. 2017 Aug 15;74(16):1253-1260. doi: 10.2146/ajhp170122. No abstract available.

PMID:
28790077
4.

The Trial of Ascertaining Individual Preferences for Loved Ones' Role in End-of-Life Decisions (TAILORED) Study: A Randomized Controlled Trial to Improve Surrogate Decision Making.

Sulmasy DP, Hughes MT, Yenokyan G, Kub J, Terry PB, Astrow AB, Johnson JA, Ho G, Nolan MT.

J Pain Symptom Manage. 2017 Oct;54(4):455-465. doi: 10.1016/j.jpainsymman.2017.07.004. Epub 2017 Jul 14.

5.

Characteristics of Participants Enrolled onto a Randomized Controlled Trial of Palliative Care for Patients on Phase I Studies.

Ferrell BR, Paterson CL, Hughes MT, Chung V, Koczywas M, Smith TJ.

J Palliat Med. 2017 Dec;20(12):1338-1344. doi: 10.1089/jpm.2017.0158. Epub 2017 Jun 13.

PMID:
28609257
6.

Patient and caregiver characteristics related to completion of advance directives in terminally ill patients.

Ho GW, Skaggs L, Yenokyan G, Kellogg A, Johnson JA, Lee MC, Heinze K, Hughes MT, Sulmasy DP, Kub J, Terry PB, Astrow AB, Zheng J, Lehmann LS, Nolan MT.

Palliat Support Care. 2017 Feb;15(1):12-19. doi: 10.1017/S147895151600016X. Epub 2016 May 30.

PMID:
27237410
7.

Decision-Making of Patients With Implantable Cardioverter-Defibrillators at End of Life: Family Members' Experiences.

Lee MC, Sulmasy DP, Gallo J, Kub J, Hughes MT, Russell S, Kellogg A, Owens SG, Terry P, Nolan MT.

Am J Hosp Palliat Care. 2017 Jul;34(6):518-523. doi: 10.1177/1049909116641622. Epub 2016 Mar 31.

PMID:
27034436
8.

Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination.

Ham J, Costa C, Sano R, Lochmann TL, Sennott EM, Patel NU, Dastur A, Gomez-Caraballo M, Krytska K, Hata AN, Floros KV, Hughes MT, Jakubik CT, Heisey DA, Ferrell JT, Bristol ML, March RJ, Yates C, Hicks MA, Nakajima W, Gowda M, Windle BE, Dozmorov MG, Garnett MJ, McDermott U, Harada H, Taylor SM, Morgan IM, Benes CH, Engelman JA, Mossé YP, Faber AC.

Cancer Cell. 2016 Feb 8;29(2):159-72. doi: 10.1016/j.ccell.2016.01.002.

9.

Symptom frequency, severity, and quality of life among persons with three disease trajectories: cancer, ALS, and CHF.

Xu J, Nolan MT, Heinze K, Yenokyan G, Hughes MT, Johnson J, Kub J, Tudor C, Sulmasy DP, Lehmann LS, Gallo JJ, Rockko F, Lee MC.

Appl Nurs Res. 2015 Nov;28(4):311-5. doi: 10.1016/j.apnr.2015.03.005. Epub 2015 Mar 13.

10.

Caring for 'Very Important Patients'--Ethical Dilemmas and Suggestions for Practical Management.

Alfandre D, Clever S, Farber NJ, Hughes MT, Redstone P, Lehmann LS.

Am J Med. 2016 Feb;129(2):143-7. doi: 10.1016/j.amjmed.2015.09.019. Epub 2015 Nov 10.

PMID:
26522793
11.

Translating Professional Obligations to Care for Patients With Ebola Virus Disease Into Practice in Nonepidemic Settings.

Sugarman J, Kass N, Rushton CH, Hughes MT, Kirsch TD.

Disaster Med Public Health Prep. 2015 Oct;9(5):527-30. doi: 10.1017/dmp.2015.61. Epub 2015 Apr 28.

PMID:
25919348
12.

Ethics skills laboratory experience for surgery interns.

Moon MR, Hughes MT, Chen JY, Khaira K, Lipsett P, Carrese JA.

J Surg Educ. 2014 Nov-Dec;71(6):829-38. doi: 10.1016/j.jsurg.2014.03.010. Epub 2014 Jul 8.

PMID:
25012607
13.

The growth of palliative care in the United States.

Hughes MT, Smith TJ.

Annu Rev Public Health. 2014;35:459-75. doi: 10.1146/annurev-publhealth-032013-182406. Review.

PMID:
24641562
14.

Analyzing reflective narratives to assess the ethical reasoning of pediatric residents.

Moon M, Taylor HA, McDonald EL, Hughes MT, Beach MC, Carrese JA.

Narrat Inq Bioeth. 2013 Fall;3(2):165-74. doi: 10.1353/nib.2013.0034.

PMID:
24407089
15.

Meeting patients where they are.

Hughes MT.

Virtual Mentor. 2013 Apr 1;15(4):293-8. doi: 10.1001/virtualmentor.2013.15.4.ecas2-1304. No abstract available.

PMID:
23566777
16.

Learner feedback and educational outcomes with an internet-based ambulatory curriculum: a qualitative and quantitative analysis.

Sisson SD, Rastegar DA, Hughes MT, Bertram AK, Yeh HC.

BMC Med Educ. 2012 Jul 12;12:55. doi: 10.1186/1472-6920-12-55.

17.

Everyday ethics in internal medicine resident clinic: an opportunity to teach.

Carrese JA, McDonald EL, Moon M, Taylor HA, Khaira K, Catherine Beach M, Hughes MT.

Med Educ. 2011 Jul;45(7):712-21. doi: 10.1111/j.1365-2923.2011.03931.x.

18.

Family understanding of seriously-ill patient preferences for family involvement in healthcare decision making.

Sharma RK, Hughes MT, Nolan MT, Tudor C, Kub J, Terry PB, Sulmasy DP.

J Gen Intern Med. 2011 Aug;26(8):881-6. doi: 10.1007/s11606-011-1717-6. Epub 2011 Apr 16.

19.

A video-intervention to improve clinician attitudes toward patients with sickle cell disease: the results of a randomized experiment.

Haywood C Jr, Lanzkron S, Hughes MT, Brown R, Massa M, Ratanawongsa N, Beach MC.

J Gen Intern Med. 2011 May;26(5):518-23. doi: 10.1007/s11606-010-1605-5. Epub 2010 Dec 23.

20.

Update in palliative medicine.

Fromme EK, Smith AK, Hughes MT, Brokaw FC, Rosenfeld KE, Arnold RM.

Am J Hosp Palliat Care. 2010 Sep;27(6):420-7. doi: 10.1177/1049909110370745. Epub 2010 Jun 16. No abstract available.

PMID:
20555038
21.

CURVES: a mnemonic for determining medical decision-making capacity and providing emergency treatment in the acute setting.

Chow GV, Czarny MJ, Hughes MT, Carrese JA.

Chest. 2010 Feb;137(2):421-7. doi: 10.1378/chest.09-1133.

PMID:
20133288
22.

Development and validation of the Family Decision-Making Self-Efficacy Scale.

Nolan MT, Hughes MT, Kub J, Terry PB, Astrow A, Thompson RE, Clawson L, Texeira K, Sulmasy DP.

Palliat Support Care. 2009 Sep;7(3):315-21. doi: 10.1017/S1478951509990241.

23.

Teaching ethics to paediatrics residents: the centrality of the therapeutic alliance.

Taylor HA, McDonald EL, Moon M, Hughes MT, Carrese JA.

Med Educ. 2009 Oct;43(10):952-9. doi: 10.1111/j.1365-2923.2009.03449.x.

PMID:
19769644
24.

Everyday ethics issues in the outpatient clinical practice of pediatric residents.

Moon M, Taylor HA, McDonald EL, Hughes MT, Carrese JA.

Arch Pediatr Adolesc Med. 2009 Sep;163(9):838-43. doi: 10.1001/archpediatrics.2009.139.

PMID:
19736338
25.

Temporal and geographic evidence for evolution of Sin Nombre virus using molecular analyses of viral RNA from Colorado, New Mexico and Montana.

Black WC 4th, Doty JB, Hughes MT, Beaty BJ, Calisher CH.

Virol J. 2009 Jul 14;6:102. doi: 10.1186/1743-422X-6-102.

26.

Interobserver variation in the histopathologic reporting of key prognostic parameters, particularly clark level, affects pathologic staging of primary cutaneous melanoma.

Murali R, Hughes MT, Fitzgerald P, Thompson JF, Scolyer RA.

Ann Surg. 2009 Apr;249(4):641-7. doi: 10.1097/SLA.0b013e31819ed973.

PMID:
19300224
27.

Are honorary authorships ethical?

Hughes MT.

Virtual Mentor. 2009 Apr 1;11(4):279-83. doi: 10.1001/virtualmentor.2009.11.4.ccas1-0904. No abstract available.

28.

Family health care decision making and self-efficacy with patients with ALS at the end of life.

Nolan MT, Kub J, Hughes MT, Terry PB, Astrow AB, Carbo CA, Thompson RE, Clawson L, Texeira K, Sulmasy DP.

Palliat Support Care. 2008 Sep;6(3):273-80. doi: 10.1017/S1478951508000412.

29.

Rapid field immunoassay for detecting antibody to Sin Nombre virus in deer mice.

Schountz T, Calisher CH, Richens TR, Rich AA, Doty JB, Hughes MT, Beaty BJ.

Emerg Infect Dis. 2007 Oct;13(10):1604-7. doi: 10.3201/eid1310.070383.

30.

Multicenter implementation of a shared graduate medical education resource.

Sisson SD, Rastegar DA, Rice TN, Hughes MT.

Arch Intern Med. 2007 Dec 10;167(22):2476-80.

PMID:
18071170
31.

How would terminally ill patients have others make decisions for them in the event of decisional incapacity? A longitudinal study.

Sulmasy DP, Hughes MT, Thompson RE, Astrow AB, Terry PB, Kub J, Nolan MT.

J Am Geriatr Soc. 2007 Dec;55(12):1981-8. Epub 2007 Nov 20.

32.

Generating sustainable towns from Chinese villages: a system modeling approach.

Levine RS, Hughes MT, Ryan Mather C, Yanarella EJ.

J Environ Manage. 2008 Apr;87(2):305-16. Epub 2007 Sep 12.

PMID:
17854975
33.
34.

Physician knowledge of national cholesterol guidelines before and after an interactive curriculum.

Sisson SD, Rice TN, Hughes MT.

Am J Cardiol. 2007 May 1;99(9):1234-5. Epub 2007 Mar 13.

PMID:
17478149
35.

Comparative potential of Aedes triseriatus, Aedes albopictus, and Aedes aegypti (Diptera: Culicidae) to transovarially transmit La Crosse virus.

Hughes MT, Gonzalez JA, Reagan KL, Blair CD, Beaty BJ.

J Med Entomol. 2006 Jul;43(4):757-61.

PMID:
16892636
36.

Physician familiarity with diagnosis and management of hypertension according to JNC 7 guidelines.

Sisson SD, Rastegar D, Rice TN, Prokopowicz G, Hughes MT.

J Clin Hypertens (Greenwich). 2006 May;8(5):344-50.

37.

Patient-requested, non-recommended screening.

Hughes MT, Ashar BH.

Virtual Mentor. 2006 Jan 1;8(1):20-3. doi: 10.1001/virtualmentor.2006.8.1.ccas3-0601. No abstract available.

38.

Current evidence for the use of emerging radiologic technologies for disease screening.

Ashar BH, Hughes MT, Marinopoulos SS, Prokopowicz GP, Berkenblit GV, Sisson SD, Simonson LA, Miller RG.

Am J Manag Care. 2005 Jun;11(6):385-92. Review.

39.

Effect of an Internet-based curriculum on postgraduate education. A multicenter intervention.

Sisson SD, Hughes MT, Levine D, Brancati FL.

J Gen Intern Med. 2004 May;19(5 Pt 2):505-9.

40.

Duty to Treat versus Personal Safety.

Hughes MT, Marcozzi D.

Virtual Mentor. 2004 May 1;6(5). pii: virtualmentor.2004.6.5.ccas1-0405. doi: 10.1001/virtualmentor.2004.6.5.ccas1-0405. No abstract available.

41.

Religious importance and practices of patients with a life-threatening illness: implications for screening protocols.

Kub JE, Nolan MT, Hughes MT, Terry PB, Sulmasy DP, Astrow A, Forman JH.

Appl Nurs Res. 2003 Aug;16(3):196-200.

PMID:
12931334
42.

Developmental- and tissue-specific expression of an inhibitor of apoptosis protein 1 homologue from Aedes triseriatus mosquitoes.

Blitvich BJ, Blair CD, Kempf BJ, Hughes MT, Black WC, Mackie RS, Meredith CT, Beaty BJ, Rayms-Keller A.

Insect Mol Biol. 2002 Oct;11(5):431-42.

PMID:
12230542
43.
44.
45.

Influenza A viruses lacking sialidase activity can undergo multiple cycles of replication in cell culture, eggs, or mice.

Hughes MT, Matrosovich M, Rodgers ME, McGregor M, Kawaoka Y.

J Virol. 2000 Jun;74(11):5206-12.

46.

Social outcomes for students with and without learning disabilities in inclusive classrooms.

Vaughn S, Elbaum BE, Schumm JS, Hughes MT.

J Learn Disabil. 1998 Sep-Oct;31(5):428-36.

PMID:
9763773
47.

Intracerebroventricular secretin enhances pancreatic volume and bicarbonate response in rats.

Conter RL, Hughes MT, Kauffman GL Jr.

Surgery. 1996 Feb;119(2):208-13.

PMID:
8571208
48.

Determinants of the initial comfort of hydrogel contact lenses.

Efron N, Brennan NA, Currie JM, Fitzgerald JP, Hughes MT.

Am J Optom Physiol Opt. 1986 Oct;63(10):819-23.

PMID:
3535525
49.

Neuroradiology, a sub-specialty.

Hughes MT.

J Neurosurg Nurs. 1972 Jul;4(1):83-91. No abstract available.

PMID:
4537754

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