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Items: 1 to 50 of 90

1.

Integrated Analys of High-Fat Challenge-Induced Changes in Blood Cell Whole-Genome Gene Expression.

Matualatupauw JC, O'Grada C, Hughes MF, Roche HM, Afman LA, Bouwman J.

Mol Nutr Food Res. 2019 Oct;63(20):e1900101. doi: 10.1002/mnfr.201900101. Epub 2019 Sep 30.

2.

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.

Salem RM, Todd JN, Sandholm N, Cole JB, Chen WM, Andrews D, Pezzolesi MG, McKeigue PM, Hiraki LT, Qiu C, Nair V, Di Liao C, Cao JJ, Valo E, Onengut-Gumuscu S, Smiles AM, McGurnaghan SJ, Haukka JK, Harjutsalo V, Brennan EP, van Zuydam N, Ahlqvist E, Doyle R, Ahluwalia TS, Lajer M, Hughes MF, Park J, Skupien J, Spiliopoulou A, Liu A, Menon R, Boustany-Kari CM, Kang HM, Nelson RG, Klein R, Klein BE, Lee KE, Gao X, Mauer M, Maestroni S, Caramori ML, de Boer IH, Miller RG, Guo J, Boright AP, Tregouet D, Gyorgy B, Snell-Bergeon JK, Maahs DM, Bull SB, Canty AJ, Palmer CNA, Stechemesser L, Paulweber B, Weitgasser R, Sokolovska J, Rovīte V, Pīrāgs V, Prakapiene E, Radzeviciene L, Verkauskiene R, Panduru NM, Groop LC, McCarthy MI, Gu HF, Möllsten A, Falhammar H, Brismar K, Martin F, Rossing P, Costacou T, Zerbini G, Marre M, Hadjadj S, McKnight AJ, Forsblom C, McKay G, Godson C, Maxwell AP, Kretzler M, Susztak K, Colhoun HM, Krolewski A, Paterson AD, Groop PH, Rich SS, Hirschhorn JN, Florez JC; SUMMIT Consortium, DCCT/EDIC Research Group, GENIE Consortium.

J Am Soc Nephrol. 2019 Oct;30(10):2000-2016. doi: 10.1681/ASN.2019030218. Epub 2019 Sep 19.

PMID:
31537649
3.

In vitro intestinal toxicity of copper oxide nanoparticles in rat and human cell models.

Henson TE, Navratilova J, Tennant AH, Bradham KD, Rogers KR, Hughes MF.

Nanotoxicology. 2019 Aug;13(6):795-811. doi: 10.1080/17435390.2019.1578428. Epub 2019 Apr 2.

PMID:
30938207
4.

The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency.

Thomas RS, Bahadori T, Buckley TJ, Cowden J, Deisenroth C, Dionisio KL, Frithsen JB, Grulke CM, Gwinn MR, Harrill JA, Higuchi M, Houck KA, Hughes MF, Hunter ES, Isaacs KK, Judson RS, Knudsen TB, Lambert JC, Linnenbrink M, Martin TM, Newton SR, Padilla S, Patlewicz G, Paul-Friedman K, Phillips KA, Richard AM, Sams R, Shafer TJ, Setzer RW, Shah I, Simmons JE, Simmons SO, Singh A, Sobus JR, Strynar M, Swank A, Tornero-Valez R, Ulrich EM, Villeneuve DL, Wambaugh JF, Wetmore BA, Williams AJ.

Toxicol Sci. 2019 Jun 1;169(2):317-332. doi: 10.1093/toxsci/kfz058.

PMID:
30835285
5.

2,4,6-Tribromophenol Disposition and Kinetics in Rodents: Effects of Dose, Route, Sex, and Species.

Knudsen GA, Trexler AW, Richards AC, Hall SM, Hughes MF, Birnbaum LS.

Toxicol Sci. 2019 May 1;169(1):167-179. doi: 10.1093/toxsci/kfz044.

PMID:
30768125
6.

Dermal disposition of Tetrabromobisphenol A Bis(2,3-dibromopropyl) ether (TBBPA-BDBPE) using rat and human skin.

Knudsen GA, Hughes MF, Birnbaum LS.

Toxicol Lett. 2019 Feb;301:108-113. doi: 10.1016/j.toxlet.2018.11.011. Epub 2018 Nov 24.

PMID:
30481582
7.

Exploring Coronary Artery Disease GWAs Targets With Functional Links to Immunometabolism.

Hughes MF, Lenighan YM, Godson C, Roche HM.

Front Cardiovasc Med. 2018 Nov 6;5:148. doi: 10.3389/fcvm.2018.00148. eCollection 2018. Review.

8.

Personalized Cardio-Metabolic Responses to an Anti-Inflammatory Nutrition Intervention in Obese Adolescents: A Randomized Controlled Crossover Trial.

McMorrow AM, Connaughton RM, Magalhães TR, McGillicuddy FC, Hughes MF, Cheishvili D, Morine MJ, Ennis S, Healy ML, Roche EF, Tremblay RE, Szyf M, Lithander FE, Roche HM.

Mol Nutr Food Res. 2018 May;62(10):e1701008. doi: 10.1002/mnfr.201701008.

9.

Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics.

Wambaugh JF, Hughes MF, Ring CL, MacMillan DK, Ford J, Fennell TR, Black SR, Snyder RW, Sipes NS, Wetmore BA, Westerhout J, Setzer RW, Pearce RG, Simmons JE, Thomas RS.

Toxicol Sci. 2018 May 1;163(1):152-169. doi: 10.1093/toxsci/kfy020.

10.

From the Cover: Genomic Effects of Androstenedione and Sex-Specific Liver Cancer Susceptibility in Mice.

Rooney JP, Ryan N, Chorley BN, Hester SD, Kenyon EM, Schmid JE, George BJ, Hughes MF, Sey YM, Tennant A, MacMillan DK, Simmons JE, McQueen CA, Pandiri A, Wood CE, Corton JC.

Toxicol Sci. 2017 Nov 1;160(1):15-29. doi: 10.1093/toxsci/kfx153.

11.

A comprehensive framework for evaluating the environmental health and safety implications of engineered nanomaterials.

Boyes WK, Thornton BLM, Al-Abed SR, Andersen CP, Bouchard DC, Burgess RM, Hubal EAC, Ho KT, Hughes MF, Kitchin K, Reichman JR, Rogers KR, Ross JA, Rygiewicz PT, Scheckel KG, Thai SF, Zepp RG, Zucker RM.

Crit Rev Toxicol. 2017 Oct;47(9):767-810. doi: 10.1080/10408444.2017.1328400. Epub 2017 Jun 29. Review. Erratum in: Crit Rev Toxicol. 2017 Oct;47(9):i.

PMID:
28661217
12.

Association of Repeatedly Measured High-Sensitivity-Assayed Troponin I with Cardiovascular Disease Events in a General Population from the MORGAM/BiomarCaRE Study.

Hughes MF, Ojeda F, Saarela O, Jørgensen T, Zeller T, Palosaari T, O'Doherty MG, Borglykke A, Kuulasmaa K, Blankenberg S, Kee F.

Clin Chem. 2017 Jan;63(1):334-342. doi: 10.1373/clinchem.2016.261172. Epub 2016 Nov 15.

13.

The biological fate of decabromodiphenyl ethane following oral, dermal or intravenous administration.

Knudsen GA, Sanders JM, Hughes MF, Hull EP, Birnbaum LS.

Xenobiotica. 2017 Oct;47(10):894-902. doi: 10.1080/00498254.2016.1250180. Epub 2016 Oct 28.

14.

Estimation of human percutaneous bioavailability for two novel brominated flame retardants, 2-ethylhexyl 2,3,4,5-tetrabromobenzoate (EH-TBB) and bis(2-ethylhexyl) tetrabromophthalate (BEH-TEBP).

Knudsen GA, Hughes MF, Sanders JM, Hall SM, Birnbaum LS.

Toxicol Appl Pharmacol. 2016 Nov 15;311:117-127. doi: 10.1016/j.taap.2016.10.005. Epub 2016 Oct 11.

15.

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S, Kleber ME, Guo X, Lyytikäinen LP, Fava C, Eriksson N, Nolte IM, Magnusson PK, Salfati EL, Rallidis LS, Theusch E, Smith AJP, Folkersen L, Witkowska K, Pers TH, Joehanes R, Kim SK, Lataniotis L, Jansen R, Johnson AD, Warren H, Kim YJ, Zhao W, Wu Y, Tayo BO, Bochud M; CHARGE-EchoGen consortium; CHARGE-HF consortium; Wellcome Trust Case Control Consortium, Absher D, Adair LS, Amin N, Arking DE, Axelsson T, Baldassarre D, Balkau B, Bandinelli S, Barnes MR, Barroso I, Bevan S, Bis JC, Bjornsdottir G, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Bornstein SR, Brown MJ, Burnier M, Cabrera CP, Chambers JC, Chang IS, Cheng CY, Chines PS, Chung RH, Collins FS, Connell JM, Döring A, Dallongeville J, Danesh J, de Faire U, Delgado G, Dominiczak AF, Doney ASF, Drenos F, Edkins S, Eicher JD, Elosua R, Enroth S, Erdmann J, Eriksson P, Esko T, Evangelou E, Evans A, Fall T, Farrall M, Felix JF, Ferrières J, Ferrucci L, Fornage M, Forrester T, Franceschini N, Duran OHF, Franco-Cereceda A, Fraser RM, Ganesh SK, Gao H, Gertow K, Gianfagna F, Gigante B, Giulianini F, Goel A, Goodall AH, Goodarzi MO, Gorski M, Gräßler J, Groves C, Gudnason V, Gyllensten U, Hallmans G, Hartikainen AL, Hassinen M, Havulinna AS, Hayward C, Hercberg S, Herzig KH, Hicks AA, Hingorani AD, Hirschhorn JN, Hofman A, Holmen J, Holmen OL, Hottenga JJ, Howard P, Hsiung CA, Hunt SC, Ikram MA, Illig T, Iribarren C, Jensen RA, Kähönen M, Kang H, Kathiresan S, Keating BJ, Khaw KT, Kim YK, Kim E, Kivimaki M, Klopp N, Kolovou G, Komulainen P, Kooner JS, Kosova G, Krauss RM, Kuh D, Kutalik Z, Kuusisto J, Kvaløy K, Lakka TA, Lee NR, Lee IT, Lee WJ, Levy D, Li X, Liang KW, Lin H, Lin L, Lindström J, Lobbens S, Männistö S, Müller G, Müller-Nurasyid M, Mach F, Markus HS, Marouli E, McCarthy MI, McKenzie CA, Meneton P, Menni C, Metspalu A, Mijatovic V, Moilanen L, Montasser ME, Morris AD, Morrison AC, Mulas A, Nagaraja R, Narisu N, Nikus K, O'Donnell CJ, O'Reilly PF, Ong KK, Paccaud F, Palmer CD, Parsa A, Pedersen NL, Penninx BW, Perola M, Peters A, Poulter N, Pramstaller PP, Psaty BM, Quertermous T, Rao DC, Rasheed A, Rayner NWNWR, Renström F, Rettig R, Rice KM, Roberts R, Rose LM, Rossouw J, Samani NJ, Sanna S, Saramies J, Schunkert H, Sebert S, Sheu WH, Shin YA, Sim X, Smit JH, Smith AV, Sosa MX, Spector TD, Stančáková A, Stanton A, Stirrups KE, Stringham HM, Sundstrom J, Swift AJ, Syvänen AC, Tai ES, Tanaka T, Tarasov KV, Teumer A, Thorsteinsdottir U, Tobin MD, Tremoli E, Uitterlinden AG, Uusitupa M, Vaez A, Vaidya D, van Duijn CM, van Iperen EPA, Vasan RS, Verwoert GC, Virtamo J, Vitart V, Voight BF, Vollenweider P, Wagner A, Wain LV, Wareham NJ, Watkins H, Weder AB, Westra HJ, Wilks R, Wilsgaard T, Wilson JF, Wong TY, Yang TP, Yao J, Yengo L, Zhang W, Zhao JH, Zhu X, Bovet P, Cooper RS, Mohlke KL, Saleheen D, Lee JY, Elliott P, Gierman HJ, Willer CJ, Franke L, Hovingh GK, Taylor KD, Dedoussis G, Sever P, Wong A, Lind L, Assimes TL, Njølstad I, Schwarz PE, Langenberg C, Snieder H, Caulfield MJ, Melander O, Laakso M, Saltevo J, Rauramaa R, Tuomilehto J, Ingelsson E, Lehtimäki T, Hveem K, Palmas W, März W, Kumari M, Salomaa V, Chen YI, Rotter JI, Froguel P, Jarvelin MR, Lakatta EG, Kuulasmaa K, Franks PW, Hamsten A, Wichmann HE, Palmer CNA, Stefansson K, Ridker PM, Loos RJF, Chakravarti A, Deloukas P, Morris AP, Newton-Cheh C, Munroe PB.

Nat Genet. 2016 Oct;48(10):1171-1184. doi: 10.1038/ng.3667. Epub 2016 Sep 12.

16.

Assessment of the in vitro dermal irritation potential of cerium, silver, and titanium nanoparticles in a human skin equivalent model.

Miyani VA, Hughes MF.

Cutan Ocul Toxicol. 2017 Jun;36(2):145-151. doi: 10.1080/15569527.2016.1211671. Epub 2016 Aug 8.

17.

Environmentally relevant pyrethroid mixtures: A study on the correlation of blood and brain concentrations of a mixture of pyrethroid insecticides to motor activity in the rat.

Hughes MF, Ross DG, Starr JM, Scollon EJ, Wolansky MJ, Crofton KM, DeVito MJ.

Toxicology. 2016 Jun 1;359-360:19-28. doi: 10.1016/j.tox.2016.06.013. Epub 2016 Jun 18.

PMID:
27330022
18.

In vivo dermal absorption of pyrethroid pesticides in the rat.

Hughes MF, Edwards BC.

J Toxicol Environ Health A. 2016;79(2):83-91. doi: 10.1080/15287394.2015.1109571. Epub 2016 Jan 28.

PMID:
26817658
19.

The Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers.

Hughes MF, Patterson CC, Appleton KM, Blankenberg S, Woodside JV, Donnelly M, Linden G, Zeller T, Esquirol Y, Kee F.

Psychosom Med. 2016 May;78(4):401-11. doi: 10.1097/PSY.0000000000000289.

PMID:
26761713
20.

Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action.

Lake AD, Wood CE, Bhat VS, Chorley BN, Carswell GK, Sey YM, Kenyon EM, Padnos B, Moore TM, Tennant AH, Schmid JE, George BJ, Ross DG, Hughes MF, Corton JC, Simmons JE, McQueen CA, Hester SD.

Toxicol Sci. 2016 Feb;149(2):312-25. doi: 10.1093/toxsci/kfv236. Epub 2015 Oct 31.

PMID:
26519955
21.

Estimation of tetrabromobisphenol A (TBBPA) percutaneous uptake in humans using the parallelogram method.

Knudsen GA, Hughes MF, McIntosh KL, Sanders JM, Birnbaum LS.

Toxicol Appl Pharmacol. 2015 Dec 1;289(2):323-9. doi: 10.1016/j.taap.2015.09.012. Epub 2015 Sep 24.

22.

Tissue time course and bioavailability of the pyrethroid insecticide bifenthrin in the Long-Evans rat.

Hughes MF, Ross DG, Edwards BC, DeVito MJ, Starr JM.

Xenobiotica. 2016;46(5):430-8. doi: 10.3109/00498254.2015.1081710. Epub 2015 Sep 14.

PMID:
26367082
23.

Predictive value of galectin-3 for incident cardiovascular disease and heart failure in the population-based FINRISK 1997 cohort.

Jagodzinski A, Havulinna AS, Appelbaum S, Zeller T, Jousilahti P, Skytte-Johanssen S, Hughes MF, Blankenberg S, Salomaa V.

Int J Cardiol. 2015 Aug 1;192:33-9. doi: 10.1016/j.ijcard.2015.05.040. Epub 2015 May 9.

PMID:
25985013
24.

ST2 may not be a useful predictor for incident cardiovascular events, heart failure and mortality.

Hughes MF, Appelbaum S, Havulinna AS, Jagodzinski A, Zeller T, Kee F, Blankenberg S, Salomaa V; FINRISK and BiomarCaRE investigators.

Heart. 2014 Nov;100(21):1715-21. doi: 10.1136/heartjnl-2014-305968. Epub 2014 Jul 30.

PMID:
25080471
25.

Environmentally relevant mixing ratios in cumulative assessments: a study of the kinetics of pyrethroids and their ester cleavage metabolites in blood and brain; and the effect of a pyrethroid mixture on the motor activity of rats.

Starr JM, Graham SE, Ross DG, Tornero-Velez R, Scollon EJ, Devito MJ, Crofton KM, Wolansky MJ, Hughes MF.

Toxicology. 2014 Jun 5;320:15-24. doi: 10.1016/j.tox.2014.02.016. Epub 2014 Mar 12.

PMID:
24631210
26.

Mouse assay for determination of arsenic bioavailability in contaminated soils.

Bradham KD, Diamond GL, Scheckel KG, Hughes MF, Casteel SW, Miller BW, Klotzbach JM, Thayer WC, Thomas DJ.

J Toxicol Environ Health A. 2013;76(13):815-26. doi: 10.1080/15287394.2013.821395.

PMID:
24028666
27.

The use of biomonitoring data in exposure and human health risk assessment: benzene case study.

Arnold SM, Angerer J, Boogaard PJ, Hughes MF, O'Lone RB, Robison SH, Schnatter AR.

Crit Rev Toxicol. 2013 Feb;43(2):119-53. doi: 10.3109/10408444.2012.756455. Review.

28.

Environmentally relevant mixtures in cumulative assessments: an acute study of toxicokinetics and effects on motor activity in rats exposed to a mixture of pyrethroids.

Starr JM, Scollon EJ, Hughes MF, Ross DG, Graham SE, Crofton KM, Wolansky MJ, Devito MJ, Tornero-Velez R.

Toxicol Sci. 2012 Dec;130(2):309-18. doi: 10.1093/toxsci/kfs245. Epub 2012 Aug 7.

PMID:
22872056
29.

A pharmacokinetic model of cis- and trans-permethrin disposition in rats and humans with aggregate exposure application.

Tornero-Velez R, Davis J, Scollon EJ, Starr JM, Setzer RW, Goldsmith MR, Chang DT, Xue J, Zartarian V, DeVito MJ, Hughes MF.

Toxicol Sci. 2012 Nov;130(1):33-47. doi: 10.1093/toxsci/kfs236. Epub 2012 Aug 1.

PMID:
22859315
30.

Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts.

Hughes MF, Saarela O, Stritzke J, Kee F, Silander K, Klopp N, Kontto J, Karvanen J, Willenborg C, Salomaa V, Virtamo J, Amouyel P, Arveiler D, Ferrières J, Wiklund PG, Baumert J, Thorand B, Diemert P, Trégouët DA, Hengstenberg C, Peters A, Evans A, Koenig W, Erdmann J, Samani NJ, Kuulasmaa K, Schunkert H.

PLoS One. 2012;7(7):e40922. doi: 10.1371/journal.pone.0040922. Epub 2012 Jul 25.

31.

Whole-body retention and distribution of orally administered radiolabelled zerovalent iron nanoparticles in mice.

Hughes MF, Long TC, Boyes WK, Ramabhadran R.

Nanotoxicology. 2013 Sep;7(6):1064-9. doi: 10.3109/17435390.2012.700337. Epub 2012 Jun 25.

PMID:
22662881
32.

In vitro metabolism of the anti-androgenic fungicide vinclozolin by rat liver microsomes.

Sierra-Santoyo A, Angeles-Soto E, de Lourdes López-González M, Harrison RA, Hughes MF.

Arch Toxicol. 2012 Mar;86(3):413-21. doi: 10.1007/s00204-011-0762-6. Epub 2011 Oct 15.

PMID:
22002493
33.

Correlation of tissue concentrations of the pyrethroid bifenthrin with neurotoxicity in the rat.

Scollon EJ, Starr JM, Crofton KM, Wolansky MJ, DeVito MJ, Hughes MF.

Toxicology. 2011 Nov 28;290(1):1-6. doi: 10.1016/j.tox.2011.08.002. Epub 2011 Aug 10.

34.

Concentration- and time-dependent genomic changes in the mouse urinary bladder following exposure to arsenate in drinking water for up to 12 weeks.

Clewell HJ, Thomas RS, Kenyon EM, Hughes MF, Adair BM, Gentry PR, Yager JW.

Toxicol Sci. 2011 Oct;123(2):421-32. doi: 10.1093/toxsci/kfr199. Epub 2011 Jul 27.

PMID:
21795629
35.

A multiple biomarker risk score for guiding clinical decisions using a decision curve approach.

Hughes MF, Saarela O, Blankenberg S, Zeller T, Havulinna AS, Kuulasmaa K, Yarnell J, Schnabel RB, Tiret L, Salomaa V, Evans A, Kee F; MORGAM project.

Eur J Prev Cardiol. 2012 Aug;19(4):874-84. doi: 10.1177/1741826711417341. Epub 2011 Jul 20.

PMID:
21775414
36.

Arsenic exposure and toxicology: a historical perspective.

Hughes MF, Beck BD, Chen Y, Lewis AS, Thomas DJ.

Toxicol Sci. 2011 Oct;123(2):305-32. doi: 10.1093/toxsci/kfr184. Epub 2011 Jul 12.

37.

Relative bioavailability and bioaccessibility and speciation of arsenic in contaminated soils.

Bradham KD, Scheckel KG, Nelson CM, Seales PE, Lee GE, Hughes MF, Miller BW, Yeow A, Gilmore T, Serda SM, Harper S, Thomas DJ.

Environ Health Perspect. 2011 Nov;119(11):1629-34. doi: 10.1289/ehp.1003352. Epub 2011 Jul 13.

38.

Arsenic (+3 oxidation state) methyltransferase genotype affects steady-state distribution and clearance of arsenic in arsenate-treated mice.

Hughes MF, Edwards BC, Herbin-Davis KM, Saunders J, Styblo M, Thomas DJ.

Toxicol Appl Pharmacol. 2010 Dec 15;249(3):217-23. doi: 10.1016/j.taap.2010.09.017. Epub 2010 Sep 29.

PMID:
20887743
39.

Accumulation of pyrethroid compounds in primary cultures from rat cortex.

Shafer TJ, Hughes MF.

Toxicol In Vitro. 2010 Oct;24(7):2053-7. doi: 10.1016/j.tiv.2010.08.016. Epub 2010 Aug 25.

PMID:
20800091
40.

In vitro dermal absorption of pyrethroid pesticides in human and rat skin.

Hughes MF, Edwards BC.

Toxicol Appl Pharmacol. 2010 Jul;246(1-2):29-37. doi: 10.1016/j.taap.2010.04.003. Epub 2010 Apr 14.

PMID:
20398685
41.

Physiologically based pharmacokinetic modeling of deltamethrin: development of a rat and human diffusion-limited model.

Godin SJ, DeVito MJ, Hughes MF, Ross DG, Scollon EJ, Starr JM, Setzer RW, Conolly RB, Tornero-Velez R.

Toxicol Sci. 2010 Jun;115(2):330-43. doi: 10.1093/toxsci/kfq051. Epub 2010 Mar 3.

PMID:
20200215
42.

Arsenic methylation, oxidative stress and cancer--is there a link?

Hughes MF.

J Natl Cancer Inst. 2009 Dec 16;101(24):1660-1. doi: 10.1093/jnci/djp437. No abstract available.

PMID:
19933940
43.

Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate.

Drobna Z, Naranmandura H, Kubachka KM, Edwards BC, Herbin-Davis K, Styblo M, Le XC, Creed JT, Maeda N, Hughes MF, Thomas DJ.

Chem Res Toxicol. 2009 Oct;22(10):1713-20. doi: 10.1021/tx900179r.

44.

Identification and functional characterization of protein kinase A-catalyzed phosphorylation of potassium channel Kv1.2 at serine 449.

Johnson RP, El-Yazbi AF, Hughes MF, Schriemer DC, Walsh EJ, Walsh MP, Cole WC.

J Biol Chem. 2009 Jun 12;284(24):16562-74. doi: 10.1074/jbc.M109.010918. Epub 2009 Apr 22.

45.

In vitro metabolism of pyrethroid pesticides by rat and human hepatic microsomes and cytochrome p450 isoforms.

Scollon EJ, Starr JM, Godin SJ, DeVito MJ, Hughes MF.

Drug Metab Dispos. 2009 Jan;37(1):221-8. doi: 10.1124/dmd.108.022343. Epub 2008 Oct 23.

PMID:
18948380
46.

Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in C57BL6 mice following subchronic exposure to arsenate in drinking water.

Kenyon EM, Hughes MF, Adair BM, Highfill JH, Crecelius EA, Clewell HJ, Yager JW.

Toxicol Appl Pharmacol. 2008 Nov 1;232(3):448-55. doi: 10.1016/j.taap.2008.07.018. Epub 2008 Jul 28.

PMID:
18706920
47.

Pharmacokinetics and dosimetry of the antiandrogen vinclozolin after oral administration in the rat.

Sierra-Santoyo A, Castañeda-Hernández G, Harrison RA, Barton HA, Hughes MF.

Toxicol Sci. 2008 Nov;106(1):55-63. doi: 10.1093/toxsci/kfn167. Epub 2008 Aug 14.

PMID:
18703562
48.

A physiologically based pharmacokinetic model for intravenous and ingested dimethylarsinic acid in mice.

Evans MV, Dowd SM, Kenyon EM, Hughes MF, El-Masri HA.

Toxicol Sci. 2008 Aug;104(2):250-60. doi: 10.1093/toxsci/kfn080. Epub 2008 Apr 21.

PMID:
18430741
49.

Tissue dosimetry, metabolism and excretion of pentavalent and trivalent dimethylated arsenic in mice after oral administration.

Hughes MF, Devesa V, Adair BM, Conklin SD, Creed JT, Styblo M, Kenyon EM, Thomas DJ.

Toxicol Appl Pharmacol. 2008 Feb 15;227(1):26-35. Epub 2007 Oct 22.

50.

Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate.

Godin SJ, Crow JA, Scollon EJ, Hughes MF, DeVito MJ, Ross MK.

Drug Metab Dispos. 2007 Sep;35(9):1664-71. Epub 2007 Jun 18.

PMID:
17576809

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