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Items: 1 to 50 of 760

1.

WITHDRAWN: Reduction versus abrupt cessation in smokers who want to quit.

Lindson N, Aveyard P, Hughes JR.

Cochrane Database Syst Rev. 2019 Oct 1;10:CD008033. doi: 10.1002/14651858.CD008033.pub4. [Epub ahead of print] Review.

PMID:
31573070
2.

Withdrawal Symptoms from E-Cigarette Abstinence Among Adult Never-Smokers: A Pilot Experimental Study.

Hughes JR, Peters EN, Callas PW, Peasley-Miklus C, Oga E, Etter JF, Morley N.

Nicotine Tob Res. 2019 Sep 3. pii: ntz169. doi: 10.1093/ntr/ntz169. [Epub ahead of print]

PMID:
31504882
3.

Transdisciplinary: Nicotine and Tobacco Research Walks the Walk.

Hughes JR.

Nicotine Tob Res. 2019 Aug 9. pii: ntz140. doi: 10.1093/ntr/ntz140. [Epub ahead of print] No abstract available.

PMID:
31398250
4.

Withdrawal Symptoms From E-Cigarette Abstinence Among Former Smokers: A Pre-Post Clinical Trial.

Hughes JR, Peters EN, Callas PW, Peasley-Miklus C, Oga E, Etter JF, Morley N.

Nicotine Tob Res. 2019 Jul 28. pii: ntz129. doi: 10.1093/ntr/ntz129. [Epub ahead of print]

PMID:
31352486
5.

Modes of cannabis use: A secondary analysis of an intensive longitudinal natural history study.

Streck JM, Hughes JR, Klemperer EM, Howard AB, Budney AJ.

Addict Behav. 2019 Nov;98:106033. doi: 10.1016/j.addbeh.2019.106033. Epub 2019 Jun 24.

PMID:
31326775
6.

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.

Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H.

Nat Metab. 2019 May;1(5):519-531. doi: 10.1038/s42255-019-0063-6. Epub 2019 May 13.

PMID:
31276102
7.

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L, Crump NT, Thorne R, Lau IJ, Repapi E, Dimou D, Smith AL, Harman JR, Telenius JM, Oudelaar AM, Downes DJ, Vyas P, Hughes JR, Milne TA.

Nat Commun. 2019 Jun 26;10(1):2803. doi: 10.1038/s41467-019-10844-3.

8.

Potential Moderating Effects of Sex/Gender on the Acute Relative Reinforcing and Subjective Effects of Reduced Nicotine Content Cigarettes in Vulnerable Populations.

Streck JM, Davis DR, Pang RD, Sigmon SC, Bunn JY, Bergeria CL, Tidey JW, Heil SH, Gaalema DE, Hughes JR, Stitzer ML, Reed E, Higgins ST.

Nicotine Tob Res. 2019 Jun 19. pii: ntz098. doi: 10.1093/ntr/ntz098. [Epub ahead of print]

PMID:
31225625
9.

High-Throughput Genotyping of CRISPR/Cas Edited Cells in 96-Well Plates.

Nussbaum L, Telenius JM, Hill S, Hirschfeld PP, Suciu MC; WIGWAM Consortium, Downes DJ, Hughes JR.

Methods Protoc. 2018 Aug 1;1(3). pii: E29. doi: 10.3390/mps1030029.

10.

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.

van Bemmel JG, Galupa R, Gard C, Servant N, Picard C, Davies J, Szempruch AJ, Zhan Y, Żylicz JJ, Nora EP, Lameiras S, de Wit E, Gentien D, Baulande S, Giorgetti L, Guttman M, Hughes JR, Higgs DR, Gribnau J, Heard E.

Nat Genet. 2019 Jun;51(6):1024-1034. doi: 10.1038/s41588-019-0412-0. Epub 2019 May 27.

PMID:
31133748
11.

Effectiveness of switching to very low nicotine content cigarettes plus nicotine patch versus reducing daily cigarette consumption plus nicotine patch to decrease dependence: an exploratory randomized trial.

Klemperer EM, Hughes JR, Callas PW, Benner JA, Morley NE.

Addiction. 2019 Sep;114(9):1639-1650. doi: 10.1111/add.14666. Epub 2019 Jun 30.

PMID:
31106492
12.

Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog.

Hughes JR, Taylor-Brown FE, Greville-Heygate O, Constantino-Casas F, Williams DL, Genain MA.

Vet Radiol Ultrasound. 2019 Mar 20. doi: 10.1111/vru.12732. [Epub ahead of print]

PMID:
30892784
13.

An Update on Hardening: A Qualitative Review.

Hughes JR.

Nicotine Tob Res. 2019 Mar 14. pii: ntz042. doi: 10.1093/ntr/ntz042. [Epub ahead of print]

PMID:
30868166
14.

Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results.

Hughes JR, Szladovits B, Drees R.

Vet Radiol Ultrasound. 2019 May;60(3):306-315. doi: 10.1111/vru.12717. Epub 2019 Feb 20.

PMID:
30786323
15.

Evaluating the utility of the modified cigarette evaluation questionnaire and cigarette purchase task for predicting acute relative reinforcing efficacy of cigarettes varying in nicotine content.

Bergeria CL, Heil SH, Davis DR, Streck JM, Sigmon SC, Bunn JY, Tidey JW, Arger CA, Reed DD, Gallagher T, Hughes JR, Gaalema DE, Stitzer ML, Higgins ST.

Drug Alcohol Depend. 2019 Apr 1;197:56-64. doi: 10.1016/j.drugalcdep.2019.01.004. Epub 2019 Feb 13.

PMID:
30776572
16.

Possible New Symptoms of Tobacco Withdrawal II: Anhedonia-A Systematic Review.

Hughes JR, Klemperer EM, Peasley-Miklus C.

Nicotine Tob Res. 2018 Aug 23. doi: 10.1093/ntr/nty171. [Epub ahead of print]

PMID:
30726957
17.

Sequential and simultaneous treatment approaches to cannabis use disorder and tobacco use.

Lee DC, Walker DD, Hughes JR, Brunette MF, Scherer E, Stanger C, Etter JF, Auty S, Budney AJ.

J Subst Abuse Treat. 2019 Mar;98:39-46. doi: 10.1016/j.jsat.2018.12.005. Epub 2018 Dec 18.

PMID:
30665602
18.

Response to reduced nicotine content cigarettes among smokers with chronic health conditions.

Streck JM, Bergeria CL, Parker MA, Davis DR, DeSarno M, Sigmon SC, Hughes JR, Gaalema DE, Heil SH, Tidey JW, Stitzer ML, Rothman M, Higgins ST.

Prev Med Rep. 2018 Oct 15;12:321-329. doi: 10.1016/j.pmedr.2018.10.001. eCollection 2018 Dec.

19.

Study characteristics influence the efficacy of substance abuse treatments: A meta-analysis of medications for smoking cessation.

Klemperer EM, Hughes JR, Naud S.

Nicotine Tob Res. 2018 Oct 20. doi: 10.1093/ntr/nty225. [Epub ahead of print]

PMID:
30380134
20.

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.

Oudelaar AM, Davies JOJ, Hanssen LLP, Telenius JM, Schwessinger R, Liu Y, Brown JM, Downes DJ, Chiariello AM, Bianco S, Nicodemi M, Buckle VJ, Dekker J, Higgs DR, Hughes JR.

Nat Genet. 2018 Dec;50(12):1744-1751. doi: 10.1038/s41588-018-0253-2. Epub 2018 Oct 29.

21.

Why we work with the tobacco industry.

Hughes JR, Fagerstrom KO, Henningfield JE, Rodu B, Rose JE, Shiffman S.

Addiction. 2019 Feb;114(2):374-375. doi: 10.1111/add.14461. Epub 2018 Nov 16. No abstract available.

PMID:
30324665
22.

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.

Brown JM, Roberts NA, Graham B, Waithe D, Lagerholm C, Telenius JM, De Ornellas S, Oudelaar AM, Scott C, Szczerbal I, Babbs C, Kassouf MT, Hughes JR, Higgs DR, Buckle VJ.

Nat Commun. 2018 Sep 21;9(1):3849. doi: 10.1038/s41467-018-06248-4.

23.

Study characteristics influence the efficacy of substance abuse treatments: A meta-analysis of medications for alcohol use disorder.

Klemperer EM, Hughes JR, Naud S.

Drug Alcohol Depend. 2018 Sep 1;190:229-234. doi: 10.1016/j.drugalcdep.2018.06.015. Epub 2018 Jul 24. Review.

PMID:
30059816
24.

Prevalence of withdrawal symptoms from electronic cigarette cessation: A cross-sectional analysis of the US Population Assessment of Tobacco and Health.

Hughes JR, Callas PW.

Addict Behav. 2019 Apr;91:234-237. doi: 10.1016/j.addbeh.2018.07.002. Epub 2018 Jul 5.

PMID:
30033197
25.

The Diversity of Nicotine and Tobacco Research.

Hughes JR.

Nicotine Tob Res. 2018 Sep 4;20(10):1161-1162. doi: 10.1093/ntr/nty100. No abstract available.

PMID:
29878240
26.

Distal Measurements can Produce False Negative Results: A Prospective Secondary Analysis of a Natural History Study.

Klemperer EM, Hughes JR, Naud S.

Nicotine Tob Res. 2018 May 25. doi: 10.1093/ntr/nty110. [Epub ahead of print]

PMID:
29800312
27.

Response to reduced nicotine content cigarettes among smokers differing in tobacco dependence severity.

Higgins ST, Bergeria CL, Davis DR, Streck JM, Villanti AC, Hughes JR, Sigmon SC, Tidey JW, Heil SH, Gaalema DE, Stitzer ML, Priest JS, Skelly JM, Reed DD, Bunn JY, Tromblee MA, Arger CA, Miller ME.

Prev Med. 2018 Dec;117:15-23. doi: 10.1016/j.ypmed.2018.04.010. Epub 2018 Apr 4.

28.

Reduction in Cigarettes per Day Prospectively Predicts Making a Quit Attempt: A Fine-Grained Secondary Analysis of a Natural History Study.

Klemperer EM, Hughes JR, Naud S.

Nicotine Tob Res. 2019 Apr 17;21(5):648-654. doi: 10.1093/ntr/nty056.

29.

HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis.

Yan T, Ooi WF, Qamra A, Cheung A, Ma D, Sundaram GM, Xu C, Xing M, Poon L, Wang J, Loh YP, Ho JHJ, Ng JJQ, Ramlee MK, Aswad L, Rozen SG, Ghosh S, Bard FA, Sampath P, Tergaonkar V, Davies JOJ, Hughes JR, Goh E, Bi X, Fullwood MJ, Tan P, Li S.

Nat Commun. 2018 Jan 8;9(1):100. doi: 10.1038/s41467-017-02601-1.

30.

Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells.

Oudelaar AM, Downes DJ, Davies JOJ, Hughes JR.

Bio Protoc. 2017 Dec 5;7(23). pii: e2645. doi: 10.21769/BioProtoc.2645.

31.

Regulation of apical blebbing in the porcine epididymis.

Hughes JR, Berger T.

J Anat. 2018 Mar;232(3):515-522. doi: 10.1111/joa.12755. Epub 2017 Dec 4.

PMID:
29205333
32.

Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C.

Oudelaar AM, Davies JOJ, Downes DJ, Higgs DR, Hughes JR.

Nucleic Acids Res. 2017 Dec 15;45(22):e184. doi: 10.1093/nar/gkx1194.

33.

Complications following laryngeal sacculectomy in brachycephalic dogs.

Hughes JR, Kaye BM, Beswick AR, Ter Haar G.

J Small Anim Pract. 2018 Jan;59(1):16-21. doi: 10.1111/jsap.12763. Epub 2017 Oct 19.

PMID:
29047114
34.

Commentary on Wu et al. (2017): Do very brief reduction interventions increase quitting among smokers not ready to quit?

Klemperer EM, Hughes JR.

Addiction. 2017 Nov;112(11):2041-2042. doi: 10.1111/add.13970. No abstract available.

PMID:
28990300
35.

Between form and function: the complexity of genome folding.

Oudelaar AM, Hanssen LLP, Hardison RC, Kassouf MT, Hughes JR, Higgs DR.

Hum Mol Genet. 2017 Oct 1;26(R2):R208-R215. doi: 10.1093/hmg/ddx306. Review.

36.

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Huang P, Keller CA, Giardine B, Grevet JD, Davies JOJ, Hughes JR, Kurita R, Nakamura Y, Hardison RC, Blobel GA.

Genes Dev. 2017 Aug 15;31(16):1704-1713. doi: 10.1101/gad.303461.117. Epub 2017 Sep 15.

37.

Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints.

Schwessinger R, Suciu MC, McGowan SJ, Telenius J, Taylor S, Higgs DR, Hughes JR.

Genome Res. 2017 Oct;27(10):1730-1742. doi: 10.1101/gr.220202.117. Epub 2017 Sep 13.

38.

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma.

Yao X, Tan J, Lim KJ, Koh J, Ooi WF, Li Z, Huang D, Xing M, Chan YS, Qu JZ, Tay ST, Wijaya G, Lam YN, Hong JH, Lee-Lim AP, Guan P, Ng MSW, He CZ, Lin JS, Nandi T, Qamra A, Xu C, Myint SS, Davies JOJ, Goh JY, Loh G, Tan BC, Rozen SG, Yu Q, Tan IBH, Cheng CWS, Li S, Chang KTE, Tan PH, Silver DL, Lezhava A, Steger G, Hughes JR, Teh BT, Tan P.

Cancer Discov. 2017 Nov;7(11):1284-1305. doi: 10.1158/2159-8290.CD-17-0375. Epub 2017 Sep 11.

39.

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR.

Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7.

40.

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.

Nat Commun. 2017 Sep 1;8(1):403. doi: 10.1038/s41467-017-00500-z.

41.

Addiction Potential of Cigarettes With Reduced Nicotine Content in Populations With Psychiatric Disorders and Other Vulnerabilities to Tobacco Addiction.

Higgins ST, Heil SH, Sigmon SC, Tidey JW, Gaalema DE, Hughes JR, Stitzer ML, Durand H, Bunn JY, Priest JS, Arger CA, Miller ME, Bergeria CL, Davis DR, Streck JM, Reed DD, Skelly JM, Tursi L.

JAMA Psychiatry. 2017 Oct 1;74(10):1056-1064. doi: 10.1001/jamapsychiatry.2017.2355. Erratum in: JAMA Psychiatry. 2018 Dec 1;75(12):1304.

42.

DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.

Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M, Graham B, Smith AJH, Lund JN, Hughes JR, Higgs DR, Tufarelli C.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7526-E7535. doi: 10.1073/pnas.1703087114. Epub 2017 Aug 21.

43.

Effectiveness of continuing nicotine replacement after a lapse: A randomized trial.

Hughes JR, Solomon LJ, Peasley-Miklus CE, Callas PW, Fingar JR.

Addict Behav. 2018 Jan;76:68-81. doi: 10.1016/j.addbeh.2017.07.023. Epub 2017 Jul 14.

PMID:
28756042
44.

Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

Hanssen LLP, Kassouf MT, Oudelaar AM, Biggs D, Preece C, Downes DJ, Gosden M, Sharpe JA, Sloane-Stanley JA, Hughes JR, Davies B, Higgs DR.

Nat Cell Biol. 2017 Aug;19(8):952-961. doi: 10.1038/ncb3573. Epub 2017 Jul 24.

45.

Development of a Self-Report Measure of Reward Sensitivity:A Test in Current and Former Smokers.

Hughes JR, Callas PW, Priest JS, Etter JF, Budney AJ, Sigmon SC.

Nicotine Tob Res. 2017 Jun 1;19(6):723-728. doi: 10.1093/ntr/ntw272.

46.

Does Tobacco Abstinence Decrease Reward Sensitivity? A Human Laboratory Test.

Hughes JR, Budney AJ, Muellers SR, Lee DC, Callas PW, Sigmon SC, Fingar JR, Priest J.

Nicotine Tob Res. 2017 Jun 1;19(6):677-685. doi: 10.1093/ntr/ntw204.

47.

Day-to-Day Variability in Self-Reported Cigarettes Per Day.

Hughes JR, Shiffman S, Naud S, Peters EN.

Nicotine Tob Res. 2017 Sep 1;19(9):1107-1111. doi: 10.1093/ntr/ntx057.

48.

A Mediation Analysis of Motivational, Reduction, and Usual Care Interventions for Smokers Who Are Not Ready to Quit.

Klemperer EM, Hughes JR, Callas PW, Solomon LJ.

Nicotine Tob Res. 2017 Aug 1;19(8):916-921. doi: 10.1093/ntr/ntx025.

49.

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo.

Simon CS, Downes DJ, Gosden ME, Telenius J, Higgs DR, Hughes JR, Costello I, Bikoff EK, Robertson EJ.

Development. 2017 Apr 1;144(7):1249-1260. doi: 10.1242/dev.147322. Epub 2017 Feb 7.

50.

Working alliance and empathy as mediators of brief telephone counseling for cigarette smokers who are not ready to quit.

Klemperer EM, Hughes JR, Callas PW, Solomon LJ.

Psychol Addict Behav. 2017 Feb;31(1):130-135. doi: 10.1037/adb0000243.

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