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Items: 1 to 50 of 745

1.

Possible New Symptoms of Tobacco Withdrawal II: Anhedonia-A Systematic Review.

Hughes JR, Klemperer EM, Peasley-Miklus C.

Nicotine Tob Res. 2018 Aug 23. doi: 10.1093/ntr/nty171. [Epub ahead of print]

PMID:
30726957
2.

Sequential and simultaneous treatment approaches to cannabis use disorder and tobacco use.

Lee DC, Walker DD, Hughes JR, Brunette MF, Scherer E, Stanger C, Etter JF, Auty S, Budney AJ.

J Subst Abuse Treat. 2019 Mar;98:39-46. doi: 10.1016/j.jsat.2018.12.005. Epub 2018 Dec 18.

PMID:
30665602
3.

Response to reduced nicotine content cigarettes among smokers with chronic health conditions.

Streck JM, Bergeria CL, Parker MA, Davis DR, DeSarno M, Sigmon SC, Hughes JR, Gaalema DE, Heil SH, Tidey JW, Stitzer ML, Rothman M, Higgins ST.

Prev Med Rep. 2018 Oct 15;12:321-329. doi: 10.1016/j.pmedr.2018.10.001. eCollection 2018 Dec.

4.

Study characteristics influence the efficacy of substance abuse treatments: A meta-analysis of medications for smoking cessation.

Klemperer EM, Hughes JR, Naud S.

Nicotine Tob Res. 2018 Oct 20. doi: 10.1093/ntr/nty225. [Epub ahead of print]

PMID:
30380134
5.

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.

Oudelaar AM, Davies JOJ, Hanssen LLP, Telenius JM, Schwessinger R, Liu Y, Brown JM, Downes DJ, Chiariello AM, Bianco S, Nicodemi M, Buckle VJ, Dekker J, Higgs DR, Hughes JR.

Nat Genet. 2018 Dec;50(12):1744-1751. doi: 10.1038/s41588-018-0253-2. Epub 2018 Oct 29.

PMID:
30374068
6.

Why we work with the tobacco industry.

Hughes JR, Fagerstrom KO, Henningfield JE, Rodu B, Rose JE, Shiffman S.

Addiction. 2019 Feb;114(2):374-375. doi: 10.1111/add.14461. Epub 2018 Nov 16. No abstract available.

PMID:
30324665
7.

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.

Brown JM, Roberts NA, Graham B, Waithe D, Lagerholm C, Telenius JM, De Ornellas S, Oudelaar AM, Scott C, Szczerbal I, Babbs C, Kassouf MT, Hughes JR, Higgs DR, Buckle VJ.

Nat Commun. 2018 Sep 21;9(1):3849. doi: 10.1038/s41467-018-06248-4.

8.

Study characteristics influence the efficacy of substance abuse treatments: A meta-analysis of medications for alcohol use disorder.

Klemperer EM, Hughes JR, Naud S.

Drug Alcohol Depend. 2018 Sep 1;190:229-234. doi: 10.1016/j.drugalcdep.2018.06.015. Epub 2018 Jul 24. Review.

PMID:
30059816
9.

Prevalence of withdrawal symptoms from electronic cigarette cessation: A cross-sectional analysis of the US Population Assessment of Tobacco and Health.

Hughes JR, Callas PW.

Addict Behav. 2019 Apr;91:234-237. doi: 10.1016/j.addbeh.2018.07.002. Epub 2018 Jul 5.

PMID:
30033197
10.

The Diversity of Nicotine and Tobacco Research.

Hughes JR.

Nicotine Tob Res. 2018 Sep 4;20(10):1161-1162. doi: 10.1093/ntr/nty100. No abstract available.

PMID:
29878240
11.

Distal Measurements can Produce False Negative Results: A Prospective Secondary Analysis of a Natural History Study.

Klemperer EM, Hughes JR, Naud S.

Nicotine Tob Res. 2018 May 25. doi: 10.1093/ntr/nty110. [Epub ahead of print]

PMID:
29800312
12.

Response to reduced nicotine content cigarettes among smokers differing in tobacco dependence severity.

Higgins ST, Bergeria CL, Davis DR, Streck JM, Villanti AC, Hughes JR, Sigmon SC, Tidey JW, Heil SH, Gaalema DE, Stitzer ML, Priest JS, Skelly JM, Reed DD, Bunn JY, Tromblee MA, Arger CA, Miller ME.

Prev Med. 2018 Dec;117:15-23. doi: 10.1016/j.ypmed.2018.04.010. Epub 2018 Apr 4.

PMID:
29626557
13.

Reduction in Cigarettes Per Day Prospectively Predicts Making a Quit Attempt: A Fine-Grained Secondary Analysis of a Natural History Study.

Klemperer EM, Hughes JR, Naud S.

Nicotine Tob Res. 2018 Mar 22. doi: 10.1093/ntr/nty056. [Epub ahead of print]

PMID:
29579250
14.

HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis.

Yan T, Ooi WF, Qamra A, Cheung A, Ma D, Sundaram GM, Xu C, Xing M, Poon L, Wang J, Loh YP, Ho JHJ, Ng JJQ, Ramlee MK, Aswad L, Rozen SG, Ghosh S, Bard FA, Sampath P, Tergaonkar V, Davies JOJ, Hughes JR, Goh E, Bi X, Fullwood MJ, Tan P, Li S.

Nat Commun. 2018 Jan 8;9(1):100. doi: 10.1038/s41467-017-02601-1.

15.

Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells.

Oudelaar AM, Downes DJ, Davies JOJ, Hughes JR.

Bio Protoc. 2017 Dec 5;7(23). pii: e2645. doi: 10.21769/BioProtoc.2645.

16.

Regulation of apical blebbing in the porcine epididymis.

Hughes JR, Berger T.

J Anat. 2018 Mar;232(3):515-522. doi: 10.1111/joa.12755. Epub 2017 Dec 4.

PMID:
29205333
17.

Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C.

Oudelaar AM, Davies JOJ, Downes DJ, Higgs DR, Hughes JR.

Nucleic Acids Res. 2017 Dec 15;45(22):e184. doi: 10.1093/nar/gkx1194.

18.

Complications following laryngeal sacculectomy in brachycephalic dogs.

Hughes JR, Kaye BM, Beswick AR, Ter Haar G.

J Small Anim Pract. 2018 Jan;59(1):16-21. doi: 10.1111/jsap.12763. Epub 2017 Oct 19.

PMID:
29047114
19.

Commentary on Wu et al. (2017): Do very brief reduction interventions increase quitting among smokers not ready to quit?

Klemperer EM, Hughes JR.

Addiction. 2017 Nov;112(11):2041-2042. doi: 10.1111/add.13970. No abstract available.

PMID:
28990300
20.

Between form and function: the complexity of genome folding.

Oudelaar AM, Hanssen LLP, Hardison RC, Kassouf MT, Hughes JR, Higgs DR.

Hum Mol Genet. 2017 Oct 1;26(R2):R208-R215. doi: 10.1093/hmg/ddx306. Review.

21.

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Huang P, Keller CA, Giardine B, Grevet JD, Davies JOJ, Hughes JR, Kurita R, Nakamura Y, Hardison RC, Blobel GA.

Genes Dev. 2017 Aug 15;31(16):1704-1713. doi: 10.1101/gad.303461.117. Epub 2017 Sep 15.

22.

Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints.

Schwessinger R, Suciu MC, McGowan SJ, Telenius J, Taylor S, Higgs DR, Hughes JR.

Genome Res. 2017 Oct;27(10):1730-1742. doi: 10.1101/gr.220202.117. Epub 2017 Sep 13.

23.

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma.

Yao X, Tan J, Lim KJ, Koh J, Ooi WF, Li Z, Huang D, Xing M, Chan YS, Qu JZ, Tay ST, Wijaya G, Lam YN, Hong JH, Lee-Lim AP, Guan P, Ng MSW, He CZ, Lin JS, Nandi T, Qamra A, Xu C, Myint SS, Davies JOJ, Goh JY, Loh G, Tan BC, Rozen SG, Yu Q, Tan IBH, Cheng CWS, Li S, Chang KTE, Tan PH, Silver DL, Lezhava A, Steger G, Hughes JR, Teh BT, Tan P.

Cancer Discov. 2017 Nov;7(11):1284-1305. doi: 10.1158/2159-8290.CD-17-0375. Epub 2017 Sep 11.

24.

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR.

Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7.

25.

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.

Nat Commun. 2017 Sep 1;8(1):403. doi: 10.1038/s41467-017-00500-z.

26.

Addiction Potential of Cigarettes With Reduced Nicotine Content in Populations With Psychiatric Disorders and Other Vulnerabilities to Tobacco Addiction.

Higgins ST, Heil SH, Sigmon SC, Tidey JW, Gaalema DE, Hughes JR, Stitzer ML, Durand H, Bunn JY, Priest JS, Arger CA, Miller ME, Bergeria CL, Davis DR, Streck JM, Reed DD, Skelly JM, Tursi L.

JAMA Psychiatry. 2017 Oct 1;74(10):1056-1064. doi: 10.1001/jamapsychiatry.2017.2355.

27.

DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.

Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M, Graham B, Smith AJH, Lund JN, Hughes JR, Higgs DR, Tufarelli C.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7526-E7535. doi: 10.1073/pnas.1703087114. Epub 2017 Aug 21.

28.

Effectiveness of continuing nicotine replacement after a lapse: A randomized trial.

Hughes JR, Solomon LJ, Peasley-Miklus CE, Callas PW, Fingar JR.

Addict Behav. 2018 Jan;76:68-81. doi: 10.1016/j.addbeh.2017.07.023. Epub 2017 Jul 14.

PMID:
28756042
29.

Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

Hanssen LLP, Kassouf MT, Oudelaar AM, Biggs D, Preece C, Downes DJ, Gosden M, Sharpe JA, Sloane-Stanley JA, Hughes JR, Davies B, Higgs DR.

Nat Cell Biol. 2017 Aug;19(8):952-961. doi: 10.1038/ncb3573. Epub 2017 Jul 24.

30.

Development of a Self-Report Measure of Reward Sensitivity:A Test in Current and Former Smokers.

Hughes JR, Callas PW, Priest JS, Etter JF, Budney AJ, Sigmon SC.

Nicotine Tob Res. 2017 Jun 1;19(6):723-728. doi: 10.1093/ntr/ntw272.

31.

Does Tobacco Abstinence Decrease Reward Sensitivity? A Human Laboratory Test.

Hughes JR, Budney AJ, Muellers SR, Lee DC, Callas PW, Sigmon SC, Fingar JR, Priest J.

Nicotine Tob Res. 2017 Jun 1;19(6):677-685. doi: 10.1093/ntr/ntw204.

32.

Day-to-Day Variability in Self-Reported Cigarettes Per Day.

Hughes JR, Shiffman S, Naud S, Peters EN.

Nicotine Tob Res. 2017 Sep 1;19(9):1107-1111. doi: 10.1093/ntr/ntx057.

33.

A Mediation Analysis of Motivational, Reduction, and Usual Care Interventions for Smokers Who Are Not Ready to Quit.

Klemperer EM, Hughes JR, Callas PW, Solomon LJ.

Nicotine Tob Res. 2017 Aug 1;19(8):916-921. doi: 10.1093/ntr/ntx025.

34.

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo.

Simon CS, Downes DJ, Gosden ME, Telenius J, Higgs DR, Hughes JR, Costello I, Bikoff EK, Robertson EJ.

Development. 2017 Apr 1;144(7):1249-1260. doi: 10.1242/dev.147322. Epub 2017 Feb 7.

35.

Working alliance and empathy as mediators of brief telephone counseling for cigarette smokers who are not ready to quit.

Klemperer EM, Hughes JR, Callas PW, Solomon LJ.

Psychol Addict Behav. 2017 Feb;31(1):130-135. doi: 10.1037/adb0000243.

36.

How best to identify chromosomal interactions: a comparison of approaches.

Davies JO, Oudelaar AM, Higgs DR, Hughes JR.

Nat Methods. 2017 Jan 31;14(2):125-134. doi: 10.1038/nmeth.4146. Review.

PMID:
28139673
37.

Updated guidance for writing a British Association of Dermatologists clinical guideline: the adoption of the GRADE methodology 2016.

Mohd Mustapa MF, Exton LS, Bell HK, Ormerod AD, Hughes JR, Levell NJ, Smith CH, McHenry PM.

Br J Dermatol. 2017 Jan;176(1):44-51. doi: 10.1111/bjd.15201. No abstract available.

PMID:
28098385
38.

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation.

Godfrey L, Kerry J, Thorne R, Repapi E, Davies JO, Tapia M, Ballabio E, Hughes JR, Geng H, Konopleva M, Milne TA.

Exp Hematol. 2017 Mar;47:64-75. doi: 10.1016/j.exphem.2016.11.003. Epub 2016 Nov 14.

39.

Gradual Versus Abrupt Smoking Cessation.

Hughes JR, Klemperer EM.

Ann Intern Med. 2016 Nov 15;165(10):741. doi: 10.7326/L16-0402. No abstract available.

PMID:
27842403
40.

Abrupt versus gradual smoking cessation with pre-cessation nicotine replacement therapy for cigarette smokers motivated to quit.

Klemperer EM, Fagerstrom KO, Hughes JR.

Ann Transl Med. 2016 Oct;4(19):384. No abstract available.

41.

Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.

Ooi WF, Xing M, Xu C, Yao X, Ramlee MK, Lim MC, Cao F, Lim K, Babu D, Poon LF, Lin Suling J, Qamra A, Irwanto A, Qu Zhengzhong J, Nandi T, Lee-Lim AP, Chan YS, Tay ST, Lee MH, Davies JO, Wong WK, Soo KC, Chan WH, Ong HS, Chow P, Wong CY, Rha SY, Liu J, Hillmer AM, Hughes JR, Rozen S, Teh BT, Fullwood MJ, Li S, Tan P.

Nat Commun. 2016 Sep 28;7:12983. doi: 10.1038/ncomms12983.

42.

Is nicotine replacement really ineffective? A reply to Stanley and Massey.

Hughes JR, Fanshawe TR, Stead LF.

J Clin Epidemiol. 2017 Jan;81:143-144. doi: 10.1016/j.jclinepi.2016.08.013. Epub 2016 Sep 20. No abstract available.

PMID:
27663610
43.

Motivational, reduction and usual care interventions for smokers who are not ready to quit: a randomized controlled trial.

Klemperer EM, Hughes JR, Solomon LJ, Callas PW, Fingar JR.

Addiction. 2017 Jan;112(1):146-155. doi: 10.1111/add.13594. Epub 2016 Oct 5.

44.

A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.

Traxler EA, Yao Y, Wang YD, Woodard KJ, Kurita R, Nakamura Y, Hughes JR, Hardison RC, Blobel GA, Li C, Weiss MJ.

Nat Med. 2016 Sep;22(9):987-90. doi: 10.1038/nm.4170. Epub 2016 Aug 15.

45.

After precessation nicotine replacement therapy, abrupt cessation increases abstinence more than gradual cessation in smokers ready to quit.

Klemperer EM, Hughes JR.

Evid Based Med. 2016 Oct;21(5):174. doi: 10.1136/ebmed-2016-110489. Epub 2016 Aug 11. No abstract available.

PMID:
27516374
46.

Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters.

Platt JL, Salama R, Smythies J, Choudhry H, Davies JO, Hughes JR, Ratcliffe PJ, Mole DR.

EMBO Rep. 2016 Oct;17(10):1410-1421. Epub 2016 Aug 8.

47.

Abstinence expectancies and quit attempts.

Hughes JR, Naud S.

Addict Behav. 2016 Dec;63:93-6. doi: 10.1016/j.addbeh.2016.07.009. Epub 2016 Jul 15.

48.

Genetic dissection of the α-globin super-enhancer in vivo.

Hay D, Hughes JR, Babbs C, Davies JOJ, Graham BJ, Hanssen L, Kassouf MT, Marieke Oudelaar AM, Sharpe JA, Suciu MC, Telenius J, Williams R, Rode C, Li PS, Pennacchio LA, Sloane-Stanley JA, Ayyub H, Butler S, Sauka-Spengler T, Gibbons RJ, Smith AJH, Wood WG, Higgs DR.

Nat Genet. 2016 Aug;48(8):895-903. doi: 10.1038/ng.3605. Epub 2016 Jul 4.

49.

Corrigendum.

Fagerström K, Hughes JR.

Addiction. 2016 Jul;111(7):1311. doi: 10.1111/add.13434. No abstract available.

PMID:
27273388
50.

Perceived role of motivation and self-efficacy in smoking cessation: A secondary data analysis.

Hughes JR, Naud S.

Addict Behav. 2016 Oct;61:58-61. doi: 10.1016/j.addbeh.2016.05.010. Epub 2016 May 12.

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