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Items: 1 to 50 of 110

1.

A conceptual replication of emotional intelligence as a second-stratum factor of intelligence.

Evans TR, Hughes DJ, Steptoe-Warren G.

Emotion. 2019 Feb 7. doi: 10.1037/emo0000569. [Epub ahead of print]

PMID:
30730169
2.

Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis.

Proença MA, Biselli JM, Succi M, Severino FE, Berardinelli GN, Caetano A, Reis RM, Hughes DJ, Silva AE.

World J Gastroenterol. 2018 Dec 21;24(47):5351-5365. doi: 10.3748/wjg.v24.i47.5351.

3.

Functional Polymorphisms in DNA Repair Genes Are Associated with Sporadic Colorectal Cancer Susceptibility and Clinical Outcome.

Jiraskova K, Hughes DJ, Brezina S, Gumpenberger T, Veskrnova V, Buchler T, Schneiderova M, Levy M, Liska V, Vodenkova S, Di Gaetano C, Naccarati A, Pardini B, Vymetalkova V, Gsur A, Vodicka P.

Int J Mol Sci. 2018 Dec 27;20(1). pii: E97. doi: 10.3390/ijms20010097.

4.

Stormwater influences phytoplankton assemblages within the diverse, but impacted Sydney Harbour estuary.

Varkey D, Mazard S, Jeffries TC, Hughes DJ, Seymour J, Paulsen IT, Ostrowski M.

PLoS One. 2018 Dec 26;13(12):e0209857. doi: 10.1371/journal.pone.0209857. eCollection 2018.

5.

Immunotherapy and pancreatic cancer: unique challenges and potential opportunities.

Young K, Hughes DJ, Cunningham D, Starling N.

Ther Adv Med Oncol. 2018 Dec 17;10:1758835918816281. doi: 10.1177/1758835918816281. eCollection 2018. Review.

6.

Putting 'Emotional Intelligences' in Their Place: Introducing the Integrated Model of Affect-Related Individual Differences.

Hughes DJ, Evans TR.

Front Psychol. 2018 Nov 14;9:2155. doi: 10.3389/fpsyg.2018.02155. eCollection 2018. Review.

7.

Expression of Selenoprotein Genes and Association with Selenium Status in Colorectal Adenoma and Colorectal Cancer.

Hughes DJ, Kunická T, Schomburg L, Liška V, Swan N, Souček P.

Nutrients. 2018 Nov 21;10(11). pii: E1812. doi: 10.3390/nu10111812.

8.

Stress-oscillation behaviour of semi-crystalline polymers: the case of poly(butylene succinate).

Wan C, Heeley EL, Zhou Y, Wang S, Cafolla CT, Crabb EM, Hughes DJ.

Soft Matter. 2018 Nov 21;14(45):9175-9184. doi: 10.1039/c8sm01889h.

PMID:
30398509
9.

Contribution of the KSHV and EBV lytic cycles to tumourigenesis.

Manners O, Murphy JC, Coleman A, Hughes DJ, Whitehouse A.

Curr Opin Virol. 2018 Oct;32:60-70. doi: 10.1016/j.coviro.2018.08.014. Epub 2018 Sep 28. Review.

10.

Roadmaps and Detours: Active Chlorophyll- a Assessments of Primary Productivity Across Marine and Freshwater Systems.

Hughes DJ, Campbell DA, Doblin MA, Kromkamp JC, Lawrenz E, Moore CM, Oxborough K, Prášil O, Ralph PJ, Alvarez MF, Suggett DJ.

Environ Sci Technol. 2018 Oct 5. doi: 10.1021/acs.est.8b03488. [Epub ahead of print]

11.

Phase separation in amorphous hydrophobically modified starch-sucrose blends: Glass transition, matrix dynamics and phase behavior.

Hughes DJ, Bönisch GB, Zwick T, Schäfer C, Tedeschi C, Leuenberger B, Martini F, Mencarini G, Geppi M, Alam MA, Ubbink J.

Carbohydr Polym. 2018 Nov 1;199:1-10. doi: 10.1016/j.carbpol.2018.06.056. Epub 2018 Jun 18.

PMID:
30143108
12.

Community-based pre-pregnancy care programme improves pregnancy preparation in women with pregestational diabetes.

Yamamoto JM, Hughes DJF, Evans ML, Karunakaran V, Clark JDA, Morrish NJ, Rayman GA, Winocour PH, Hambling C, Harries AW, Sampson MJ, Murphy HR.

Diabetologia. 2018 May 9. doi: 10.1007/s00125-018-4613-3. [Epub ahead of print]

PMID:
29744539
13.

Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies.

Edington CD, Chen WLK, Geishecker E, Kassis T, Soenksen LR, Bhushan BM, Freake D, Kirschner J, Maass C, Tsamandouras N, Valdez J, Cook CD, Parent T, Snyder S, Yu J, Suter E, Shockley M, Velazquez J, Velazquez JJ, Stockdale L, Papps JP, Lee I, Vann N, Gamboa M, LaBarge ME, Zhong Z, Wang X, Boyer LA, Lauffenburger DA, Carrier RL, Communal C, Tannenbaum SR, Stokes CL, Hughes DJ, Rohatgi G, Trumper DL, Cirit M, Griffith LG.

Sci Rep. 2018 Mar 14;8(1):4530. doi: 10.1038/s41598-018-22749-0.

14.

Prospective evaluation of antibody response to Streptococcus gallolyticus and risk of colorectal cancer.

Butt J, Jenab M, Willhauck-Fleckenstein M, Michel A, Pawlita M, Kyrø C, Tjønneland A, Boutron-Ruault MC, Carbonnel F, Severi G, Kaaks R, Kühn T, Boeing H, Trichopoulou A, la Vecchia C, Karakatsani A, Panico S, Tumino R, Agnoli C, Palli D, Sacerdote C, Bueno-de-Mesquita HBA, Weiderpass E, Sánchez MJ, Bonet Bonet C, Huerta JM, Ardanaz E, Bradbury K, Gunter M, Murphy N, Freisling H, Riboli E, Tsilidis K, Aune D, Waterboer T, Hughes DJ.

Int J Cancer. 2018 Jul 15;143(2):245-252. doi: 10.1002/ijc.31283. Epub 2018 Feb 14.

15.

Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.

Hughes DJ, Tiede C, Penswick N, Tang AA, Trinh CH, Mandal U, Zajac KZ, Gaule T, Howell G, Edwards TA, Duan J, Feyfant E, McPherson MJ, Tomlinson DC, Whitehouse A.

Sci Signal. 2017 Nov 14;10(505). pii: eaaj2005. doi: 10.1126/scisignal.aaj2005.

16.

Isolation of isoform-specific binding proteins (Affimers) by phage display using negative selection.

Tang AA, Tiede C, Hughes DJ, McPherson MJ, Tomlinson DC.

Sci Signal. 2017 Nov 14;10(505). pii: eaan0868. doi: 10.1126/scisignal.aan0868.

17.

Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome.

Lemstrova R, Brynychova V, Hughes DJ, Hlavac V, Dvorak P, Doherty JE, Murray HA, Crockard M, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Lovecek M, Havlik R, Ehrmann J, Strouhal O, Soucek P, Melichar B, Mohelnikova-Duchonova B.

Oncol Lett. 2017 Nov;14(5):5980-5988. doi: 10.3892/ol.2017.6946. Epub 2017 Sep 14.

18.

Leader dark traits, workplace bullying, and employee depression: Exploring mediation and the role of the dark core.

Tokarev A, Phillips AR, Hughes DJ, Irwing P.

J Abnorm Psychol. 2017 Oct;126(7):911-920. doi: 10.1037/abn0000299.

PMID:
29106276
19.

Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk.

Chen WLK, Edington C, Suter E, Yu J, Velazquez JJ, Velazquez JG, Shockley M, Large EM, Venkataramanan R, Hughes DJ, Stokes CL, Trumper DL, Carrier RL, Cirit M, Griffith LG, Lauffenburger DA.

Biotechnol Bioeng. 2017 Nov;114(11):2648-2659. doi: 10.1002/bit.26370. Epub 2017 Jul 27.

20.

Pre-diagnostic copper and zinc biomarkers and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort.

Stepien M, Jenab M, Freisling H, Becker NP, Czuban M, Tjønneland A, Olsen A, Overvad K, Boutron-Ruault MC, Mancini FR, Savoye I, Katzke V, Kühn T, Boeing H, Iqbal K, Trichopoulou A, Bamia C, Orfanos P, Palli D, Sieri S, Tumino R, Naccarati A, Panico S, Bueno-de-Mesquita HBA, Peeters PH, Weiderpass E, Merino S, Jakszyn P, Sanchez MJ, Dorronsoro M, Huerta JM, Barricarte A, Boden S, van Guelpen B, Wareham N, Khaw KT, Bradbury KE, Cross AJ, Schomburg L, Hughes DJ.

Carcinogenesis. 2017 Jul 1;38(7):699-707. doi: 10.1093/carcin/bgx051.

21.

Opportunities and challenges in the wider adoption of liver and interconnected microphysiological systems.

Hughes DJ, Kostrzewski T, Sceats EL.

Exp Biol Med (Maywood). 2017 Oct;242(16):1593-1604. doi: 10.1177/1535370217708976. Epub 2017 May 15. Review.

22.

Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System.

Sarkar U, Ravindra KC, Large E, Young CL, Rivera-Burgos D, Yu J, Cirit M, Hughes DJ, Wishnok JS, Lauffenburger DA, Griffith LG, Tannenbaum SR.

Drug Metab Dispos. 2017 Jul;45(7):855-866. doi: 10.1124/dmd.116.074005. Epub 2017 Apr 27.

23.

The missing link? The potential role of selenium in the development of liver cancer and significance for the general population.

Schomburg L, Hughes DJ.

Expert Rev Gastroenterol Hepatol. 2017 Aug;11(8):707-709. doi: 10.1080/17474124.2017.1320219. Epub 2017 Apr 21. No abstract available.

PMID:
28415859
24.

SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival.

Mohelnikova-Duchonova B, Strouhal O, Hughes DJ, Holcatova I, Oliverius M, Kala Z, Campa D, Rizzato C, Canzian F, Pezzilli R, Talar-Wojnarowska R, Malecka-Panas E, Sperti C, Federico Zambon C, Pedrazzoli S, Fogar P, Milanetto AC, Capurso G, Delle Fave G, Valente R, Gazouli M, Malleo G, Teresa Lawlor R, Strobel O, Hackert T, Giese N, Vodicka P, Vodickova L, Landi S, Tavano F, Gioffreda D, Piepoli A, Pazienza V, Mambrini A, Pedata M, Cantore M, Bambi F, Ermini S, Funel N, Lemstrova R, Soucek P.

Sci Rep. 2017 Mar 8;7:43812. doi: 10.1038/srep43812.

25.

Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans.

Stepien M, Hughes DJ, Hybsier S, Bamia C, Tjønneland A, Overvad K, Affret A, His M, Boutron-Ruault MC, Katzke V, Kühn T, Aleksandrova K, Trichopoulou A, Lagiou P, Orfanos P, Palli D, Sieri S, Tumino R, Ricceri F, Panico S, Bueno-de-Mesquita HB, Peeters PH, Weiderpass E, Lasheras C, Bonet Bonet C, Molina-Portillo E, Dorronsoro M, Huerta JM, Barricarte A, Ohlsson B, Sjöberg K, Werner M, Shungin D, Wareham N, Khaw KT, Travis RC, Freisling H, Cross AJ, Schomburg L, Jenab M.

Br J Cancer. 2017 Feb 28;116(5):688-696. doi: 10.1038/bjc.2017.1. Epub 2017 Feb 2.

26.

Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease.

Kostrzewski T, Cornforth T, Snow SA, Ouro-Gnao L, Rowe C, Large EM, Hughes DJ.

World J Gastroenterol. 2017 Jan 14;23(2):204-215. doi: 10.3748/wjg.v23.i2.204.

27.

Ecosystem uptake and transfer of Sellafield-derived radiocarbon (14C) part 2: The West of Scotland.

Tierney KM, Muir GKP, Cook GT, MacKinnon G, Howe JA, Heymans JJ, Hughes DJ, Xu S.

Mar Pollut Bull. 2017 Feb 15;115(1-2):57-66. doi: 10.1016/j.marpolbul.2016.11.014. Epub 2016 Nov 26.

28.

Comparative genomics to explore phylogenetic relationship, cryptic sexual potential and host specificity of Rhynchosporium species on grasses.

Penselin D, Münsterkötter M, Kirsten S, Felder M, Taudien S, Platzer M, Ashelford K, Paskiewicz KH, Harrison RJ, Hughes DJ, Wolf T, Shelest E, Graap J, Hoffmann J, Wenzel C, Wöltje N, King KM, Fitt BD, Güldener U, Avrova A, Knogge W.

BMC Genomics. 2016 Nov 22;17(1):953.

29.

Ecosystem uptake and transfer of Sellafield-derived radiocarbon (14C). Part 1. The Irish Sea.

Muir GK, Tierney KM, Cook GT, MacKinnon G, Howe JA, Heymans JJ, Hughes DJ, Xu S.

Mar Pollut Bull. 2017 Jan 30;114(2):792-804. doi: 10.1016/j.marpolbul.2016.10.072. Epub 2016 Nov 10.

30.

Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System.

Tsamandouras N, Kostrzewski T, Stokes CL, Griffith LG, Hughes DJ, Cirit M.

J Pharmacol Exp Ther. 2017 Jan;360(1):95-105. Epub 2016 Oct 19.

31.

Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216.

Mohelnikova-Duchonova B, Kocik M, Duchonova B, Brynychova V, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Ojima I, Hughes DJ, Doherty JE, Murray HA, Crockard MA, Lemstrova R, Soucek P.

Pharmacogenomics J. 2017 Oct;17(5):452-460. doi: 10.1038/tpj.2016.55. Epub 2016 Aug 30.

PMID:
27573236
32.

ARID3B: a Novel Regulator of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycle.

Wood JJ, Boyne JR, Paulus C, Jackson BR, Nevels MM, Whitehouse A, Hughes DJ.

J Virol. 2016 Sep 29;90(20):9543-55. doi: 10.1128/JVI.03262-15. Print 2016 Oct 15.

33.

Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort.

Hughes DJ, Duarte-Salles T, Hybsier S, Trichopoulou A, Stepien M, Aleksandrova K, Overvad K, Tjønneland A, Olsen A, Affret A, Fagherazzi G, Boutron-Ruault MC, Katzke V, Kaaks R, Boeing H, Bamia C, Lagiou P, Peppa E, Palli D, Krogh V, Panico S, Tumino R, Sacerdote C, Bueno-de-Mesquita HB, Peeters PH, Engeset D, Weiderpass E, Lasheras C, Agudo A, Sánchez MJ, Navarro C, Ardanaz E, Dorronsoro M, Hemmingsson O, Wareham NJ, Khaw KT, Bradbury KE, Cross AJ, Gunter M, Riboli E, Romieu I, Schomburg L, Jenab M.

Am J Clin Nutr. 2016 Aug;104(2):406-14. doi: 10.3945/ajcn.116.131672. Epub 2016 Jun 29.

34.

Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration.

Yu J, Cilfone NA, Large EM, Sarkar U, Wishnok JS, Tannenbaum SR, Hughes DJ, Lauffenburger DA, Griffith LG, Stokes CL, Cirit M.

CPT Pharmacometrics Syst Pharmacol. 2015 Oct;4(10):585-94. doi: 10.1002/psp4.12010. Epub 2015 Oct 5.

35.

Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease.

Václavíková R, Hughes DJ, Souček P.

Gene. 2015 Oct 15;571(1):1-8. doi: 10.1016/j.gene.2015.07.071. Epub 2015 Jul 26. Review.

36.

Ecological impacts of large-scale disposal of mining waste in the deep sea.

Hughes DJ, Shimmield TM, Black KD, Howe JA.

Sci Rep. 2015 May 5;5:9985. doi: 10.1038/srep09985.

37.

Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor.

Sarkar U, Rivera-Burgos D, Large EM, Hughes DJ, Ravindra KC, Dyer RL, Ebrahimkhani MR, Wishnok JS, Griffith LG, Tannenbaum SR.

Drug Metab Dispos. 2015 Jul;43(7):1091-9. doi: 10.1124/dmd.115.063495. Epub 2015 Apr 29.

38.

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression.

Aherne ST, Madden SF, Hughes DJ, Pardini B, Naccarati A, Levy M, Vodicka P, Neary P, Dowling P, Clynes M.

BMC Cancer. 2015 Apr 30;15:329. doi: 10.1186/s12885-015-1327-5.

39.

NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target.

Hughes DJ, Wood JJ, Jackson BR, Baquero-Pérez B, Whitehouse A.

PLoS Pathog. 2015 Mar 20;11(3):e1004771. doi: 10.1371/journal.ppat.1004771. eCollection 2015 Mar.

40.

Resolution of the cellular proteome of the nucleocapsid protein from a highly pathogenic isolate of porcine reproductive and respiratory syndrome virus identifies PARP-1 as a cellular target whose interaction is critical for virus biology.

Liu L, Lear Z, Hughes DJ, Wu W, Zhou EM, Whitehouse A, Chen H, Hiscox JA.

Vet Microbiol. 2015 Mar 23;176(1-2):109-19. doi: 10.1016/j.vetmic.2014.11.023. Epub 2014 Dec 30.

41.

Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer.

Dowling P, Hughes DJ, Larkin AM, Meiller J, Henry M, Meleady P, Lynch V, Pardini B, Naccarati A, Levy M, Vodicka P, Neary P, Clynes M.

Clin Chim Acta. 2015 Feb 20;441:133-41. doi: 10.1016/j.cca.2014.12.005. Epub 2014 Dec 23.

PMID:
25540887
42.

Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract.

Leeming GH, Kipar A, Hughes DJ, Bingle L, Bennett E, Moyo NA, Tripp RA, Bigley AL, Bingle CD, Sample JT, Stewart JP.

Lab Invest. 2015 Jun;95(6):610-24. doi: 10.1038/labinvest.2014.162. Epub 2014 Dec 22.

43.

Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis.

Munday DC, Wu W, Smith N, Fix J, Noton SL, Galloux M, Touzelet O, Armstrong SD, Dawson JM, Aljabr W, Easton AJ, Rameix-Welti MA, de Oliveira AP, Simabuco FM, Ventura AM, Hughes DJ, Barr JN, Fearns R, Digard P, Eléouët JF, Hiscox JA.

J Virol. 2015 Jan 15;89(2):917-30. doi: 10.1128/JVI.01783-14. Epub 2014 Oct 29.

44.

Hepatitis C core antigen testing: a reliable, quick, and potentially cost-effective alternative to hepatitis C polymerase chain reaction in diagnosing acute hepatitis C virus infection.

Cresswell FV, Fisher M, Hughes DJ, Shaw SG, Homer G, Hassan-Ibrahim MO.

Clin Infect Dis. 2015 Jan 15;60(2):263-6. doi: 10.1093/cid/ciu782. Epub 2014 Oct 9.

PMID:
25301216
45.

Utilising proteomic approaches to understand oncogenic human herpesviruses (Review).

Owen CB, Hughes DJ, Baquero-Perez B, Berndt A, Schumann S, Jackson BR, Whitehouse A.

Mol Clin Oncol. 2014 Nov;2(6):891-903. Epub 2014 Jul 9.

46.

Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort.

Hughes DJ, Fedirko V, Jenab M, Schomburg L, Méplan C, Freisling H, Bueno-de-Mesquita HB, Hybsier S, Becker NP, Czuban M, Tjønneland A, Outzen M, Boutron-Ruault MC, Racine A, Bastide N, Kühn T, Kaaks R, Trichopoulos D, Trichopoulou A, Lagiou P, Panico S, Peeters PH, Weiderpass E, Skeie G, Dagrun E, Chirlaque MD, Sánchez MJ, Ardanaz E, Ljuslinder I, Wennberg M, Bradbury KE, Vineis P, Naccarati A, Palli D, Boeing H, Overvad K, Dorronsoro M, Jakszyn P, Cross AJ, Quirós JR, Stepien M, Kong SY, Duarte-Salles T, Riboli E, Hesketh JE.

Int J Cancer. 2015 Mar 1;136(5):1149-61. doi: 10.1002/ijc.29071. Epub 2014 Jul 21.

47.

Large-scale analysis of influenza A virus nucleoprotein sequence conservation reveals potential drug-target sites.

Kukol A, Hughes DJ.

Virology. 2014 Apr;454-455:40-7. doi: 10.1016/j.virol.2014.01.023. Epub 2014 Feb 22.

48.

Exploratory structural equation modeling of personality data.

Booth T, Hughes DJ.

Assessment. 2014 Jun;21(3):260-71. doi: 10.1177/1073191114528029. Epub 2014 Mar 28.

PMID:
24682748
49.

Bioreactor technologies to support liver function in vitro.

Ebrahimkhani MR, Neiman JA, Raredon MS, Hughes DJ, Griffith LG.

Adv Drug Deliv Rev. 2014 Apr;69-70:132-57. doi: 10.1016/j.addr.2014.02.011. Epub 2014 Mar 5. Review.

50.

Fusobacterium nucleatum associates with stages of colorectal neoplasia development, colorectal cancer and disease outcome.

Flanagan L, Schmid J, Ebert M, Soucek P, Kunicka T, Liska V, Bruha J, Neary P, Dezeeuw N, Tommasino M, Jenab M, Prehn JH, Hughes DJ.

Eur J Clin Microbiol Infect Dis. 2014 Aug;33(8):1381-90. doi: 10.1007/s10096-014-2081-3. Epub 2014 Mar 6.

PMID:
24599709

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