Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 170

1.

Multiple genes recruited from hormone pathways partition maize diterpenoid defences.

Ding Y, Murphy KM, Poretsky E, Mafu S, Yang B, Char SN, Christensen SA, Saldivar E, Wu M, Wang Q, Ji L, Schmitz RJ, Kremling KA, Buckler ES, Shen Z, Briggs SP, Bohlmann J, Sher A, Castro-Falcon G, Hughes CC, Huffaker A, Zerbe P, Schmelz EA.

Nat Plants. 2019 Oct;5(10):1043-1056. doi: 10.1038/s41477-019-0509-6. Epub 2019 Sep 16.

PMID:
31527844
2.

Progress toward the Total Synthesis of Lymphostins: Preparation of a Functionalized Tetrahydropyrrolo[4,3,2-de]quinoline and Unusual Oxidative Dimerization.

Seiler GS, Hughes CC.

J Org Chem. 2019 Jul 19;84(14):9339-9343. doi: 10.1021/acs.joc.9b01041. Epub 2019 Jun 27.

PMID:
31246453
3.

Nature's Combinatorial Biosynthesis Produces Vatiamides A-F.

Moss NA, Seiler G, Leão TF, Castro-Falcón G, Gerwick L, Hughes CC, Gerwick WH.

Angew Chem Int Ed Engl. 2019 Jul 1;58(27):9027-9031. doi: 10.1002/anie.201902571. Epub 2019 May 28.

PMID:
31071229
4.

Impact of Electronic Health Record Systems on Prescribing Errors in Pediatric Clinics.

Gildon BL, Condren M, Hughes CC.

Healthcare (Basel). 2019 Apr 5;7(2). pii: E57. doi: 10.3390/healthcare7020057.

5.

Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions.

Faal T, Phan DTT, Davtyan H, Scarfone VM, Varady E, Blurton-Jones M, Hughes CCW, Inlay MA.

Stem Cell Reports. 2019 Mar 5;12(3):451-460. doi: 10.1016/j.stemcr.2019.01.005. Epub 2019 Feb 7.

6.

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA Jr, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.

ACS Cent Sci. 2018 Dec 26;4(12):1727-1741. doi: 10.1021/acscentsci.8b00747. Epub 2018 Dec 5.

7.

Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels.

Gaetani R, Aouad S, Demaddalena LL, Straessle H, Dzieciatkowska M, Wortham M, Bender HR, Nguyen-Ngoc KV, Schmid-Schoenbein GW, George SC, Hughes CCW, Sander M, Hansen KC, Christman KL.

Tissue Eng Part C Methods. 2018 Nov 6. doi: 10.1089/ten.TEC.2018.0180. [Epub ahead of print]

PMID:
30398401
8.

Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester.

Castro-Falcón G, Seiler GS, Demir Ö, Rathinaswamy MK, Hamelin D, Hoffmann RM, Makowski SL, Letzel AC, Field SJ, Burke JE, Amaro RE, Hughes CC.

J Med Chem. 2018 Dec 13;61(23):10463-10472. doi: 10.1021/acs.jmedchem.8b00975. Epub 2018 Nov 28.

PMID:
30380865
9.

Nitrosopyridine Probe To Detect Polyketide Natural Products with Conjugated Alkenes: Discovery of Novodaryamide and Nocarditriene.

Castro-Falcón G, Millán-Aguiñaga N, Roullier C, Jensen PR, Hughes CC.

ACS Chem Biol. 2018 Nov 16;13(11):3097-3106. doi: 10.1021/acschembio.8b00598. Epub 2018 Oct 26.

PMID:
30272441
10.

Multiscale modeling of glioblastoma.

Yan H, Romero-López M, Benitez LI, Di K, Frieboes HB, Hughes CCW, Bota DA, Lowengrub JS.

Transl Cancer Res. 2018 Feb;7(Suppl 1):S96-S98. doi: 10.21037/tcr.2017.12.10. No abstract available.

11.

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia.

Faughnan ME, Gossage JR, Chakinala MM, Oh SP, Kasthuri R, Hughes CCW, McWilliams JP, Parambil JG, Vozoris N, Donaldson J, Paul G, Berry P, Sprecher DL.

Angiogenesis. 2019 Feb;22(1):145-155. doi: 10.1007/s10456-018-9646-1. Epub 2018 Sep 6.

12.

Applications of tumor chip technology.

Hachey SJ, Hughes CCW.

Lab Chip. 2018 Sep 26;18(19):2893-2912. doi: 10.1039/c8lc00330k. Review.

13.

A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function.

Wang X, Zhao D, Phan DTT, Liu J, Chen X, Yang B, Hughes CCW, Zhang W, Lee AP.

Lab Chip. 2018 Jul 24;18(15):2167-2177. doi: 10.1039/c8lc00236c.

14.

The role of inter-species interactions in Salinispora specialized metabolism.

Patin NV, Floros DJ, Hughes CC, Dorrestein PC, Jensen PR.

Microbiology. 2018 Jul;164(7):946-955. doi: 10.1099/mic.0.000679. Epub 2018 Jun 7.

15.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.

16.

Discovery, Biosynthesis and Stress-Related Accumulation of Dolabradiene-Derived Defenses in Maize.

Mafu S, Ding Y, Murphy KM, Yaacoobi O, Addison JB, Wang Q, Shen Z, Briggs SP, Bohlmann J, Castro-Falcon G, Hughes CC, Betsiashvili M, Huffaker A, Schmelz EA, Zerbe P.

Plant Physiol. 2018 Apr;176(4):2677-2690. doi: 10.1104/pp.17.01351. Epub 2018 Feb 23.

17.

Executive summary of the 12th HHT international scientific conference.

Andrejecsk JW, Hosman AE, Botella LM, Shovlin CL, Arthur HM, Dupuis-Girod S, Buscarini E, Hughes CCW, Lebrin F, Mummery CL, Post MC, Mager JJ.

Angiogenesis. 2018 Feb;21(1):169-181. doi: 10.1007/s10456-017-9585-2.

18.

3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels.

Wang X, Phan DTT, George SC, Hughes CCW, Lee AP.

Methods Mol Biol. 2017;1612:325-344. doi: 10.1007/978-1-4939-7021-6_24.

PMID:
28634954
19.

3D Mathematical Modeling of Glioblastoma Suggests That Transdifferentiated Vascular Endothelial Cells Mediate Resistance to Current Standard-of-Care Therapy.

Yan H, Romero-López M, Benitez LI, Di K, Frieboes HB, Hughes CCW, Bota DA, Lowengrub JS.

Cancer Res. 2017 Aug 1;77(15):4171-4184. doi: 10.1158/0008-5472.CAN-16-3094. Epub 2017 May 23.

20.

Ecological implications of hypoxia-triggered shifts in secondary metabolism.

Gallagher KA, Wanger G, Henderson J, Llorente M, Hughes CC, Jensen PR.

Environ Microbiol. 2017 Jun;19(6):2182-2191. doi: 10.1111/1462-2920.13700. Epub 2017 Mar 21.

21.

Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface.

Phan DT, Bender RHF, Andrejecsk JW, Sobrino A, Hachey SJ, George SC, Hughes CC.

Exp Biol Med (Maywood). 2017 Nov;242(17):1669-1678. doi: 10.1177/1535370217694100. Epub 2017 Feb 14. Review.

22.

A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications.

Phan DTT, Wang X, Craver BM, Sobrino A, Zhao D, Chen JC, Lee LYN, George SC, Lee AP, Hughes CCW.

Lab Chip. 2017 Jan 31;17(3):511-520. doi: 10.1039/c6lc01422d.

PMID:
28092382
23.

Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts.

Reimer D, Hughes CC.

J Nat Prod. 2017 Jan 27;80(1):126-133. doi: 10.1021/acs.jnatprod.6b00773. Epub 2017 Jan 5.

PMID:
28055208
24.

Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth.

Romero-López M, Trinh AL, Sobrino A, Hatch MM, Keating MT, Fimbres C, Lewis DE, Gershon PD, Botvinick EL, Digman M, Lowengrub JS, Hughes CC.

Biomaterials. 2017 Feb;116:118-129. doi: 10.1016/j.biomaterials.2016.11.034. Epub 2016 Nov 24.

25.

Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression Without Increasing Invasiveness.

Yan H, Romero-Lopez M, Frieboes HB, Hughes CC, Lowengrub JS.

IEEE Trans Biomed Eng. 2017 Mar;64(3):538-548. doi: 10.1109/TBME.2016.2615566. Epub 2016 Oct 7.

26.

3D microtumors in vitro supported by perfused vascular networks.

Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CC.

Sci Rep. 2016 Aug 23;6:31589. doi: 10.1038/srep31589.

27.

Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering.

Arulmoli J, Wright HJ, Phan DTT, Sheth U, Que RA, Botten GA, Keating M, Botvinick EL, Pathak MM, Zarembinski TI, Yanni DS, Razorenova OV, Hughes CCW, Flanagan LA.

Acta Biomater. 2016 Oct 1;43:122-138. doi: 10.1016/j.actbio.2016.07.043. Epub 2016 Jul 27.

28.

Three-Dimensional Adult Cardiac Extracellular Matrix Promotes Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Fong AH, Romero-López M, Heylman CM, Keating M, Tran D, Sobrino A, Tran AQ, Pham HH, Fimbres C, Gershon PD, Botvinick EL, George SC, Hughes CC.

Tissue Eng Part A. 2016 Aug;22(15-16):1016-25. doi: 10.1089/ten.TEA.2016.0027.

29.

Thiol Probes To Detect Electrophilic Natural Products Based on Their Mechanism of Action.

Castro-Falcón G, Hahn D, Reimer D, Hughes CC.

ACS Chem Biol. 2016 Aug 19;11(8):2328-36. doi: 10.1021/acschembio.5b00924. Epub 2016 Jun 28.

31.

New Curculionoidea records from New Brunswick, Canada with an addition to the fauna of Nova Scotia.

Webster RP, Anderson RS, Webster VL, Alderson CA, Hughes CC, Sweeney JD.

Zookeys. 2016 Mar 24;(573):367-86. doi: 10.3897/zookeys.573.7444. eCollection 2016.

32.

The Ciidae (Coleoptera) of New Brunswick, Canada: New records and new synonyms.

Lopes-Andrade C, Webster RP, Webster VL, Alderson CA, Hughes CC, Sweeney JD.

Zookeys. 2016 Mar 24;(573):339-66. doi: 10.3897/zookeys.573.7445. eCollection 2016.

33.

Further contributions to the Coleoptera fauna of New Brunswick with an addition to the fauna of Nova Scotia, Canada.

Webster RP, Webster VL, Alderson CA, Hughes CC, Sweeney JD.

Zookeys. 2016 Mar 24;(573):265-338. doi: 10.3897/zookeys.573.7327. eCollection 2016.

34.

Further contributions to the Aleocharinae (Coleoptera, Staphylinidae) fauna of New Brunswick and Canada including descriptions of 27 new species.

Webster RP, Klimaszewski J, Bourdon C, Sweeney JD, Hughes CC, Labrecque M.

Zookeys. 2016 Mar 24;(573):85-216. doi: 10.3897/zookeys.573.7016. eCollection 2016.

35.

mTORC2 mediates CXCL12-induced angiogenesis.

Ziegler ME, Hatch MM, Wu N, Muawad SA, Hughes CC.

Angiogenesis. 2016 Jul;19(3):359-71. doi: 10.1007/s10456-016-9509-6. Epub 2016 Apr 22.

36.

Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma.

Freimark BD, Gong J, Ye D, Gray MJ, Nguyen V, Yin S, Hatch MM, Hughes CC, Schroit AJ, Hutchins JT, Brekken RA, Huang X.

Cancer Immunol Res. 2016 Jun;4(6):531-40. doi: 10.1158/2326-6066.CIR-15-0250. Epub 2016 Apr 4.

37.

An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms.

Wang X, Phan DTT, Zhao D, George SC, Hughes CCW, Lee AP.

Lab Chip. 2016 Mar 7;16(5):868-876. doi: 10.1039/c5lc01563d.

38.

Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels.

Wang X, Phan DT, Sobrino A, George SC, Hughes CC, Lee AP.

Lab Chip. 2016 Jan 21;16(2):282-90. doi: 10.1039/c5lc01050k.

39.

Executive summary of the 11th HHT international scientific conference.

Arthur H, Geisthoff U, Gossage JR, Hughes CC, Lacombe P, Meek ME, Oh P, Roman BL, Trerotola SO, Velthuis S, Wooderchak-Donahue W.

Angiogenesis. 2015 Oct;18(4):511-24. doi: 10.1007/s10456-015-9482-5.

PMID:
26391603
40.

A theoretical and empirical review of psychological factors associated with falls-related psychological concerns in community-dwelling older people.

Hughes CC, Kneebone II, Jones F, Brady B.

Int Psychogeriatr. 2015 Jul;27(7):1071-87. doi: 10.1017/S1041610214002701. Epub 2015 Jan 30. Review.

PMID:
25633917
41.

A role for partial endothelial-mesenchymal transitions in angiogenesis?

Welch-Reardon KM, Wu N, Hughes CC.

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):303-8. doi: 10.1161/ATVBAHA.114.303220. Epub 2014 Nov 25. Review.

42.

Sioxanthin, a novel glycosylated carotenoid, reveals an unusual subclustered biosynthetic pathway.

Richter TK, Hughes CC, Moore BS.

Environ Microbiol. 2015 Jun;17(6):2158-71. doi: 10.1111/1462-2920.12669. Epub 2014 Dec 11.

43.

A three-dimensional in vitro model of tumor cell intravasation.

Ehsan SM, Welch-Reardon KM, Waterman ML, Hughes CC, George SC.

Integr Biol (Camb). 2014 Jun;6(6):603-10. doi: 10.1039/c3ib40170g.

44.

A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening.

Heylman C, Sobrino A, Shirure VS, Hughes CC, George SC.

Exp Biol Med (Maywood). 2014 Sep;239(9):1240-54. doi: 10.1177/1535370214525295. Epub 2014 Apr 16. Review.

45.

Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis.

Popson SA, Ziegler ME, Chen X, Holderfield MT, Shaaban CI, Fong AH, Welch-Reardon KM, Papkoff J, Hughes CC.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):1011-9. doi: 10.1161/ATVBAHA.114.303352. Epub 2014 Mar 6.

46.

Implanted cell-dense prevascularized tissues develop functional vasculature that supports reoxygenation after thrombosis.

White SM, Pittman CR, Hingorani R, Arora R, Esipova TV, Vinogradov SA, Hughes CC, Choi B, George SC.

Tissue Eng Part A. 2014 Sep;20(17-18):2316-28. doi: 10.1089/ten.TEA.2013.0311. Epub 2014 Jun 30.

47.

Facial asymmetry associated with a mixed radiolucent-radiopaque change of the maxillofacial bones.

Woo VL, Pharar J, Herschaft EE, Hughes CC, Akerson HA, Danforth RA.

J Am Dent Assoc. 2014 Mar;145(3):274-9. doi: 10.14219/jada.2013.42. No abstract available.

PMID:
24583893
48.

Angiogenic sprouting is regulated by endothelial cell expression of Slug.

Welch-Reardon KM, Ehsan SM, Wang K, Wu N, Newman AC, Romero-Lopez M, Fong AH, George SC, Edwards RA, Hughes CC.

J Cell Sci. 2014 May 1;127(Pt 9):2017-28. doi: 10.1242/jcs.143420. Epub 2014 Feb 19.

49.

A screen for short-range paracrine interactions.

Spencer KH, Kim MY, Hughes CC, Hui EE.

Integr Biol (Camb). 2014 Apr;6(4):382-7. doi: 10.1039/c3ib40211h. Epub 2014 Feb 13.

50.

Purported Mcl-1 inhibitor marinopyrrole A fails to show selective cytotoxicity for Mcl-1-dependent cell lines.

Eichhorn JM, Alford SE, Hughes CC, Fenical W, Chambers TC.

Cell Death Dis. 2013 Oct 24;4:e880. doi: 10.1038/cddis.2013.411. No abstract available.

Supplemental Content

Loading ...
Support Center