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Items: 10

1.

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice.

Loeb KR, Hughes BT, Fissel BM, Osteen NJ, Knoblaugh SE, Grim JE, Drury LJ, Sarver A, Dupuy AJ, Clurman BE.

Sci Rep. 2019 Apr 2;9(1):5488. doi: 10.1038/s41598-019-41805-x.

2.

The PP2A-B56 Phosphatase Opposes Cyclin E Autocatalytic Degradation via Site-Specific Dephosphorylation.

Davis RJ, Swanger J, Hughes BT, Clurman BE.

Mol Cell Biol. 2017 Mar 31;37(8). pii: e00657-16. doi: 10.1128/MCB.00657-16. Print 2017 Apr 15.

3.

Cytoplasmic localization of Hug1p, a negative regulator of the MEC1 pathway, coincides with the compartmentalization of Rnr2p-Rnr4p.

Ainsworth WB, Hughes BT, Au WC, Sakelaris S, Kerscher O, Benton MG, Basrai MA.

Biochem Biophys Res Commun. 2013 Oct 4;439(4):443-8. doi: 10.1016/j.bbrc.2013.08.089. Epub 2013 Sep 5.

4.

Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation.

Hughes BT, Sidorova J, Swanger J, Monnat RJ Jr, Clurman BE.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):8954-9. doi: 10.1073/pnas.1302927110. Epub 2013 May 13.

5.

Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding.

Lee CY, Yeh TL, Hughes BT, Espenshade PJ.

Mol Cell. 2011 Oct 21;44(2):225-34. doi: 10.1016/j.molcel.2011.08.031.

6.

Degradation of sterol regulatory element-binding protein precursor requires the endoplasmic reticulum-associated degradation components Ubc7 and Hrd1 in fission yeast.

Hughes BT, Nwosu CC, Espenshade PJ.

J Biol Chem. 2009 Jul 31;284(31):20512-21. doi: 10.1074/jbc.M109.002436. Epub 2009 Jun 11.

7.

Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast.

Lee CY, Stewart EV, Hughes BT, Espenshade PJ.

EMBO J. 2009 Jan 21;28(2):135-43. doi: 10.1038/emboj.2008.271.

8.

Fecal incontinence in an inpatient population: a not uncommon finding.

Hughes BT, Chepyala P, Hendon S, Crowell MD, Olden KW.

Dig Dis Sci. 2009 Oct;54(10):2215-9. doi: 10.1007/s10620-008-0592-4. Epub 2008 Dec 5.

PMID:
19058001
9.

Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member.

Hughes BT, Espenshade PJ.

EMBO J. 2008 May 21;27(10):1491-501. doi: 10.1038/emboj.2008.83. Epub 2008 Apr 17.

10.

Oxygen-dependent, alternative promoter controls translation of tco1+ in fission yeast.

Sehgal A, Hughes BT, Espenshade PJ.

Nucleic Acids Res. 2008 Apr;36(6):2024-31. doi: 10.1093/nar/gkn027. Epub 2008 Feb 14.

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