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Items: 1 to 50 of 372

1.

To drain or not to drain following a Sistrunk procedure: A dual institutional experience.

Brooks JA, Cunningham MJ, Koempel JA, Kawai K, Huang JK, Weitzman RE, Osterbauer B, Hughes AL.

Int J Pediatr Otorhinolaryngol. 2019 Aug 19;127:109645. doi: 10.1016/j.ijporl.2019.109645. [Epub ahead of print]

PMID:
31494373
2.

Knowing When to Let Go: Lysosomes Regulate Inter-Mitochondrial Tethering.

English AM, Hughes AL.

Dev Cell. 2019 Aug 5;50(3):259-260. doi: 10.1016/j.devcel.2019.07.019.

PMID:
31386859
3.

Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress.

Goodrum JM, Lever AR, Coody TK, Gottschling DE, Hughes AL.

Mol Biol Cell. 2019 Aug 1;30(17):2141-2154. doi: 10.1091/mbc.E19-02-0094. Epub 2019 May 29.

PMID:
31141470
4.

Advancing the aging biology toolkit.

Coody TK, Hughes AL.

Elife. 2018 Nov 28;7. pii: e42976. doi: 10.7554/eLife.42976.

5.

Teaching a tracheotomy handoff tool to pediatric first responders.

Murray N, Valdez TA, Hughes AL, Kavanagh KR.

Int J Pediatr Otorhinolaryngol. 2018 Nov;114:120-123. doi: 10.1016/j.ijporl.2018.08.003. Epub 2018 Aug 7.

PMID:
30262348
6.

Author Correction: Interplay of grounding-line dynamics and sub-shelf melting during retreat of the Bjørnøyrenna Ice Stream.

Petrini M, Colleoni F, Kirchner N, Hughes ALC, Camerlenghi A, Rebesco M, Lucchi RG, Forte E, Colucci RR, Noormets R.

Sci Rep. 2018 Aug 21;8(1):12819. doi: 10.1038/s41598-018-30242-x.

7.

Greenland ice mass loss during the Younger Dryas driven by Atlantic Meridional Overturning Circulation feedbacks.

Rainsley E, Menviel L, Fogwill CJ, Turney CSM, Hughes ALC, Rood DH.

Sci Rep. 2018 Aug 9;8(1):11307. doi: 10.1038/s41598-018-29226-8.

8.

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome.

Sundaramoorthy R, Hughes AL, El-Mkami H, Norman DG, Ferreira H, Owen-Hughes T.

Elife. 2018 Aug 6;7. pii: e35720. doi: 10.7554/eLife.35720.

9.

Interplay of grounding-line dynamics and sub-shelf melting during retreat of the Bjørnøyrenna Ice Stream.

Petrini M, Colleoni F, Kirchner N, Hughes ALC, Camerlenghi A, Rebesco M, Lucchi RG, Forte E, Colucci RR, Noormets R.

Sci Rep. 2018 May 8;8(1):7196. doi: 10.1038/s41598-018-25664-6. Erratum in: Sci Rep. 2018 Aug 21;8(1):12819.

10.

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact.

Shai N, Yifrach E, van Roermund CWT, Cohen N, Bibi C, IJlst L, Cavellini L, Meurisse J, Schuster R, Zada L, Mari MC, Reggiori FM, Hughes AL, Escobar-Henriques M, Cohen MM, Waterham HR, Wanders RJA, Schuldiner M, Zalckvar E.

Nat Commun. 2018 May 2;9(1):1761. doi: 10.1038/s41467-018-03957-8.

11.

Minimal Holocene retreat of large tidewater glaciers in Køge Bugt, southeast Greenland.

Dyke LM, Andresen CS, Seidenkrantz MS, Hughes ALC, Hiemstra JF, Murray T, Bjørk AA, Sutherland DA, Vermassen F.

Sci Rep. 2017 Sep 26;7(1):12330. doi: 10.1038/s41598-017-12018-x.

12.

Factors associated with patient no-show rates in an academic otolaryngology practice.

Fiorillo CE, Hughes AL, I-Chen C, Westgate PM, Gal TJ, Bush ML, Comer BT.

Laryngoscope. 2018 Mar;128(3):626-631. doi: 10.1002/lary.26816. Epub 2017 Aug 16.

13.

Appropriateness of Tympanostomy Tubes in the Boston Metropolitan Area: Are the AAO-HNSF Guidelines Being Met?

Hughes AL, Roberson D, Bannos C, Trudell EK, Vernacchio L.

Otolaryngol Head Neck Surg. 2017 Dec;157(6):1041-1047. doi: 10.1177/0194599817721454. Epub 2017 Jul 25.

PMID:
28741408
14.

Avoidance of APOBEC3B-induced mutation by error-free lesion bypass.

Hoopes JI, Hughes AL, Hobson LA, Cortez LM, Brown AJ, Roberts SA.

Nucleic Acids Res. 2017 May 19;45(9):5243-5254. doi: 10.1093/nar/gkx169.

15.

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.

Sundaramoorthy R, Hughes AL, Singh V, Wiechens N, Ryan DP, El-Mkami H, Petoukhov M, Svergun DI, Treutlein B, Quack S, Fischer M, Michaelis J, Böttcher B, Norman DG, Owen-Hughes T.

Elife. 2017 Mar 23;6. pii: e22510. doi: 10.7554/eLife.22510.

16.

Deciphering Subunit-Specific Functions within SWI/SNF Complexes.

Hughes AL, Owen-Hughes T.

Cell Rep. 2017 Feb 28;18(9):2075-2076. doi: 10.1016/j.celrep.2017.02.045. Review.

17.

Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function.

Bello NA, Hyacinth HI, Roetker NS, Seals SR, Naik RP, Derebail VK, Kshirsagar AV, Key NS, Wilson JG, Correa A, Adams RJ, Egede LD, Longstreth WT Jr, Choudhary G, Gee BE, Hughes AL, Shah AM, Manson JE, Allison M, Burke GL, Folsom AR, Carty CL, Reiner AP, Solomon SD, Konety SH.

Blood. 2017 Feb 9;129(6):799-801. doi: 10.1182/blood-2016-08-705541. Epub 2016 Dec 8. No abstract available.

18.

Arteriviruses, Pegiviruses, and Lentiviruses Are Common among Wild African Monkeys.

Bailey AL, Lauck M, Ghai RR, Nelson CW, Heimbruch K, Hughes AL, Goldberg TL, Kuhn JH, Jasinska AJ, Freimer NB, Apetrei C, O'Connor DH.

J Virol. 2016 Jul 11;90(15):6724-6737. doi: 10.1128/JVI.00573-16. Print 2016 Aug 1.

19.

The crucial impact of lysosomes in aging and longevity.

Carmona-Gutierrez D, Hughes AL, Madeo F, Ruckenstuhl C.

Ageing Res Rev. 2016 Dec;32:2-12. doi: 10.1016/j.arr.2016.04.009. Epub 2016 Apr 26. Review.

20.

Selective sorting and destruction of mitochondrial membrane proteins in aged yeast.

Hughes AL, Hughes CE, Henderson KA, Yazvenko N, Gottschling DE.

Elife. 2016 Apr 20;5. pii: e13943. doi: 10.7554/eLife.13943.

21.

Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus.

Moncla LH, Zhong G, Nelson CW, Dinis JM, Mutschler J, Hughes AL, Watanabe T, Kawaoka Y, Friedrich TC.

Cell Host Microbe. 2016 Feb 10;19(2):169-80. doi: 10.1016/j.chom.2016.01.011.

22.

Natural selection of K13 mutants of Plasmodium falciparum in response to artemisinin combination therapies in Thailand.

Putaporntip C, Kuamsab N, Kosuwin R, Tantiwattanasub W, Vejakama P, Sueblinvong T, Seethamchai S, Jongwutiwes S, Hughes AL.

Clin Microbiol Infect. 2016 Mar;22(3):285.e1-8. doi: 10.1016/j.cmi.2015.10.027. Epub 2015 Nov 5.

23.

Conditional Immune Escape during Chronic Simian Immunodeficiency Virus Infection.

Gellerup DD, Balgeman AJ, Nelson CW, Ericsen AJ, Scarlotta M, Hughes AL, O'Connor SL.

J Virol. 2015 Oct 21;90(1):545-52. doi: 10.1128/JVI.02587-15. Print 2016 Jan 1.

24.

SNPGenie: estimating evolutionary parameters to detect natural selection using pooled next-generation sequencing data.

Nelson CW, Moncla LH, Hughes AL.

Bioinformatics. 2015 Nov 15;31(22):3709-11. doi: 10.1093/bioinformatics/btv449. Epub 2015 Jul 29.

25.

Life-history evolution at the molecular level: adaptive amino acid composition of avian vitellogenins.

Hughes AL.

Proc Biol Sci. 2015 Aug 7;282(1812):20151105. doi: 10.1098/rspb.2015.1105.

26.

Comparative Genomics Reveals Chd1 as a Determinant of Nucleosome Spacing in Vivo.

Hughes AL, Rando OJ.

G3 (Bethesda). 2015 Jul 14;5(9):1889-97. doi: 10.1534/g3.115.020271.

27.

IgG4-Related Disease Presenting as a Neck Mass.

Hughes AL, Comer BT.

Otolaryngol Head Neck Surg. 2015 Sep;153(3):476-7. doi: 10.1177/0194599815594354. Epub 2015 Jul 13. No abstract available.

PMID:
26170118
28.

Selection Maintains Low Genomic GC Content in Marine SAR11 Lineages.

Luo H, Thompson LR, Stingl U, Hughes AL.

Mol Biol Evol. 2015 Oct;32(10):2738-48. doi: 10.1093/molbev/msv149. Epub 2015 Jun 27.

PMID:
26116859
29.

Stability of social behavior in captive American Flamingos (Phoenicopterus ruber): A quantitative case study.

Hughes AL.

Zoo Biol. 2015 Jul-Aug;34(4):305-13. doi: 10.1002/zoo.21215. Epub 2015 Apr 17.

PMID:
25884784
30.

Adaptive amino acid composition in collagens of parasitic nematodes.

Hughes AL.

Infect Genet Evol. 2015 Apr;31:277-83. doi: 10.1016/j.meegid.2015.02.002. Epub 2015 Feb 11.

PMID:
25681700
31.

A pediatric soft palate mass. Pleomorphic adenoma.

Hughes AL, Yang E, Vargas SO.

JAMA Otolaryngol Head Neck Surg. 2015 Apr;141(4):391-2. doi: 10.1001/jamaoto.2014.3722. No abstract available.

PMID:
25675156
32.

Power(2): the power of yeast genetics applied to the powerhouse of the cell.

Rutter J, Hughes AL.

Trends Endocrinol Metab. 2015 Feb;26(2):59-68. doi: 10.1016/j.tem.2014.12.002. Epub 2015 Jan 12. Review.

33.

Cross-clade simultaneous HIV drug resistance genotyping for reverse transcriptase, protease, and integrase inhibitor mutations by Illumina MiSeq.

Dudley DM, Bailey AL, Mehta SH, Hughes AL, Kirk GD, Westergaard RP, O'Connor DH.

Retrovirology. 2014 Dec 23;11:122. doi: 10.1186/s12977-014-0122-8.

34.

Evolutionary diversification of insect innexins.

Hughes AL.

J Insect Sci. 2014 Jan 1;14. pii: 221. doi: 10.1093/jisesa/ieu083. Print 2014.

35.

Within-host nucleotide diversity of virus populations: insights from next-generation sequencing.

Nelson CW, Hughes AL.

Infect Genet Evol. 2015 Mar;30:1-7. doi: 10.1016/j.meegid.2014.11.026. Epub 2014 Dec 4. Review.

36.

Management of a large antenatally recognized foregut duplication cyst of the tongue causing respiratory distress at birth.

Gantwerker EA, Hughes AL, Silvera VM, Vargas SO, Rahbar R.

JAMA Otolaryngol Head Neck Surg. 2014 Nov;140(11):1065-9. doi: 10.1001/jamaoto.2014.2331.

PMID:
25317853
37.

Mother-daughter asymmetry of pH underlies aging and rejuvenation in yeast.

Henderson KA, Hughes AL, Gottschling DE.

Elife. 2014 Sep 4;3:e03504. doi: 10.7554/eLife.03504.

38.

Evolutionary diversification of the vertebrate transferrin multi-gene family.

Hughes AL, Friedman R.

Immunogenetics. 2014 Nov;66(11):651-61. doi: 10.1007/s00251-014-0798-x. Epub 2014 Aug 22.

39.

Mechanisms underlying nucleosome positioning in vivo.

Hughes AL, Rando OJ.

Annu Rev Biophys. 2014;43:41-63. doi: 10.1146/annurev-biophys-051013-023114. Review.

PMID:
24702039
40.

Evolutionary diversification of aminopeptidase N in Lepidoptera by conserved clade-specific amino acid residues.

Hughes AL.

Mol Phylogenet Evol. 2014 Jul;76:127-33. doi: 10.1016/j.ympev.2014.03.014. Epub 2014 Mar 24.

41.

High genetic diversity and adaptive potential of two simian hemorrhagic fever viruses in a wild primate population.

Bailey AL, Lauck M, Weiler A, Sibley SD, Dinis JM, Bergman Z, Nelson CW, Correll M, Gleicher M, Hyeroba D, Tumukunde A, Weny G, Chapman C, Kuhn JH, Hughes AL, Friedrich TC, Goldberg TL, O'Connor DH.

PLoS One. 2014 Mar 20;9(3):e90714. doi: 10.1371/journal.pone.0090714. eCollection 2014. Erratum in: PLoS One. 2014;9(7):e102939.

42.

Comparing effective population sizes of dominant marine alphaproteobacteria lineages.

Luo H, Swan BK, Stepanauskas R, Hughes AL, Moran MA.

Environ Microbiol Rep. 2014 Apr;6(2):167-72. doi: 10.1111/1758-2229.12129. Epub 2013 Dec 5.

PMID:
24596290
43.

Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesterone.

Scholtz EL, Krishnan S, Ball BA, Corbin CJ, Moeller BC, Stanley SD, McDowell KJ, Hughes AL, McDonnell DP, Conley AJ.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3365-70. doi: 10.1073/pnas.1318163111. Epub 2014 Feb 18.

44.

Evolutionary analysis of a streamlined lineage of surface ocean Roseobacters.

Luo H, Swan BK, Stepanauskas R, Hughes AL, Moran MA.

ISME J. 2014 Jul;8(7):1428-39. doi: 10.1038/ismej.2013.248. Epub 2014 Jan 23.

45.

Dexamethasone otoprotection in a multidose cisplatin ototoxicity mouse model.

Hughes AL, Hussain N, Pafford R, Parham K.

Otolaryngol Head Neck Surg. 2014 Jan;150(1):115-20. doi: 10.1177/0194599813511948. Epub 2013 Nov 14.

PMID:
24233060
46.

Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses.

Wilker PR, Dinis JM, Starrett G, Imai M, Hatta M, Nelson CW, O'Connor DH, Hughes AL, Neumann G, Kawaoka Y, Friedrich TC.

Nat Commun. 2013;4:2636. doi: 10.1038/ncomms3636.

47.

Evolution of divergent life history strategies in marine alphaproteobacteria.

Luo H, Csuros M, Hughes AL, Moran MA.

MBio. 2013 Jul 9;4(4). pii: e00373-13. doi: 10.1128/mBio.00373-13.

48.

Evolution of the salivary apyrases of blood-feeding arthropods.

Hughes AL.

Gene. 2013 Sep 15;527(1):123-30. doi: 10.1016/j.gene.2013.05.087. Epub 2013 Jun 18.

PMID:
23791653
49.

A novel hepacivirus with an unusually long and intrinsically disordered NS5A protein in a wild Old World primate.

Lauck M, Sibley SD, Lara J, Purdy MA, Khudyakov Y, Hyeroba D, Tumukunde A, Weny G, Switzer WM, Chapman CA, Hughes AL, Friedrich TC, O'Connor DH, Goldberg TL.

J Virol. 2013 Aug;87(16):8971-81. doi: 10.1128/JVI.00888-13. Epub 2013 Jun 5.

50.

Acute phase CD8+ T lymphocytes against alternate reading frame epitopes select for rapid viral escape during SIV infection.

Walsh AD, Bimber BN, Das A, Piaskowski SM, Rakasz EG, Bean AT, Mudd PA, Ericsen AJ, Wilson NA, Hughes AL, O'Connor DH, Maness NJ.

PLoS One. 2013 May 6;8(5):e61383. doi: 10.1371/journal.pone.0061383. Print 2013.

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