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Items: 1 to 50 of 489

1.

Type 2 diabetes does not account for ethnic differences in exercise capacity or skeletal muscle function in older adults.

Jones S, Tillin T, Williams S, Eastwood SV, Hughes AD, Chaturvedi N.

Diabetologia. 2019 Dec 9. doi: 10.1007/s00125-019-05055-w. [Epub ahead of print]

PMID:
31820039
2.

Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts.

Hughes AD, Zhao D, Dai H, Abou-Daya KI, Tieu R, Rammal R, Williams AL, Landsittel DP, Shlomchik WD, Morelli AE, Oberbarnscheidt MH, Lakkis FG.

J Clin Invest. 2019 Nov 25. pii: 125773. doi: 10.1172/JCI125773. [Epub ahead of print]

3.

Influence of renal transplantation and living kidney donation on large artery stiffness and peripheral vascular resistance.

Buus NH, Carlsen RK, Hughes AD, Skov K.

Am J Hypertens. 2019 Nov 3. pii: hpz175. doi: 10.1093/ajh/hpz175. [Epub ahead of print]

PMID:
31678997
4.

Impact of Kidney Function on Cardiovascular Risk and Mortality: A Comparison of South Asian and European Cohorts.

Eastwood SV, Chaturvedi N, Sattar N, Welsh PI, Hughes AD, Tillin T.

Am J Nephrol. 2019;50(6):425-433. doi: 10.1159/000503873. Epub 2019 Oct 30.

5.

Reproducibility of Left Ventricular Dyssynchrony Indices by Three-Dimensional Speckle-Tracking Echocardiography: The Impact of Sub-optimal Image Quality.

Al Saikhan L, Park C, Hughes AD.

Front Cardiovasc Med. 2019 Oct 10;6:149. doi: 10.3389/fcvm.2019.00149. eCollection 2019.

6.

Determinants of Intima-Media Thickness in the Young: The ALSPAC Study.

Chiesa ST, Charakida M, Georgiopoulos G, Dangardt F, Wade KH, Rapala A, Bhowruth DJ, Nguyen HC, Muthurangu V, Shroff R, Davey Smith G, Lawlor DA, Sattar N, Timpson NJ, Hughes AD, Deanfield JE.

JACC Cardiovasc Imaging. 2019 Oct 11. pii: S1936-878X(19)30875-7. doi: 10.1016/j.jcmg.2019.08.026. [Epub ahead of print]

7.

A Multicenter, Scan-Rescan, Human and Machine Learning CMR Study to Test Generalizability and Precision in Imaging Biomarker Analysis.

Bhuva AN, Bai W, Lau C, Davies RH, Ye Y, Bulluck H, McAlindon E, Culotta V, Swoboda PP, Captur G, Treibel TA, Augusto JB, Knott KD, Seraphim A, Cole GD, Petersen SE, Edwards NC, Greenwood JP, Bucciarelli-Ducci C, Hughes AD, Rueckert D, Moon JC, Manisty CH.

Circ Cardiovasc Imaging. 2019 Oct;12(10):e009214. doi: 10.1161/CIRCIMAGING.119.009214. Epub 2019 Sep 24.

PMID:
31547689
8.

Response to 'Does smoking or alcohol cause early vascular damage in teenage years?'

Charakida M, Georgiopoulos G, Dangardt F, Chiesa ST, Hughes AD, Rapala A, Davey Smith G, Lawlor D, Finer N, Deanfield JE.

Eur Heart J. 2019 Nov 1;40(42):3497. doi: 10.1093/eurheartj/ehz608. No abstract available.

PMID:
31511879
9.

Non-invasive assessment of ventriculo-arterial coupling using aortic wave intensity analysis combining central blood pressure and phase-contrast cardiovascular magnetic resonance.

Bhuva AN, D'Silva A, Torlasco C, Nadarajan N, Jones S, Boubertakh R, Van Zalen J, Scully P, Knott K, Benedetti G, Augusto JB, Bastiaenen R, Lloyd G, Sharma S, Moon JC, Parker KH, Manisty CH, Hughes AD.

Eur Heart J Cardiovasc Imaging. 2019 Sep 9. pii: jez227. doi: 10.1093/ehjci/jez227. [Epub ahead of print]

PMID:
31501858
10.

Identification of Distinct Arterial Waveform Clusters and a Longitudinal Evaluation of Their Clinical Usefulness.

Sluyter JD, Hughes AD, Camargo CA Jr, Thom SAM, Parker KH, Hametner B, Wassertheurer S, Scragg R.

Hypertension. 2019 Oct;74(4):921-928. doi: 10.1161/HYPERTENSIONAHA.119.12625. Epub 2019 Aug 26.

PMID:
31446803
11.

Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking.

Uejima T, Dunstan FD, Arbustini E, Łoboz-Grudzień K, Hughes AD, Carerj S, Favalli V, Antonini-Canterin F, Vriz O, Vinereanu D, Zamorano JL, Popescu BA, Evangelista A, Lancellotti P, Lefthériotis G, Kozakova M, Palombo C, Fraser AG; E-Tracking International Collaboration Group (ETIC).

J Hum Hypertens. 2019 Aug 21. doi: 10.1038/s41371-019-0228-5. [Epub ahead of print]

PMID:
31435004
12.

Computational simulations of thrombolysis in acute stroke: Effect of clot size and location on recanalisation.

Gu B, Piebalgs A, Huang Y, Roi D, Lobotesis K, Longstaff C, Hughes AD, Chen R, Thom SA, Xu XY.

Med Eng Phys. 2019 Nov;73:9-17. doi: 10.1016/j.medengphy.2019.07.014. Epub 2019 Aug 8.

PMID:
31402315
13.

Associations between family history and coronary artery calcium and coronary heart disease in British Europeans and South Asians.

Wang J, Tillin T, Hughes AD, Chaturvedi N.

Int J Cardiol. 2019 Aug 1. pii: S0167-5273(19)31994-1. doi: 10.1016/j.ijcard.2019.07.101. [Epub ahead of print]

14.

The relationship between pubertal timing and markers of vascular and cardiac structure and function in men and women aged 60-64 years.

Hardy R, Maddock J, Ghosh AK, Hughes AD, Kuh D.

Sci Rep. 2019 Jul 30;9(1):11037. doi: 10.1038/s41598-019-47164-x.

15.

Masked hypertension and submaximal exercise blood pressure among adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC).

Huang Z, Sharman JE, Fonseca R, Park C, Chaturvedi N, Davey Smith G, Howe LD, Lawlor DA, Hughes AD, Schultz MG.

Scand J Med Sci Sports. 2020 Jan;30(1):25-30. doi: 10.1111/sms.13525. Epub 2019 Aug 22.

PMID:
31353626
16.

Automatic optic disc detection in colour fundus images by means of multispectral analysis and information content.

Martinez-Perez ME, Witt N, Parker KH, Hughes AD, Thom SAM.

PeerJ. 2019 Jun 27;7:e7119. doi: 10.7717/peerj.7119. eCollection 2019.

17.

Sex and regional differences in myocardial plasticity in aortic stenosis are revealed by 3D model machine learning.

Bhuva AN, Treibel TA, De Marvao A, Biffi C, Dawes TJW, Doumou G, Bai W, Patel K, Boubertakh R, Rueckert D, O'Regan DP, Hughes AD, Moon JC, Manisty CH.

Eur Heart J Cardiovasc Imaging. 2019 Jul 5. pii: jez166. doi: 10.1093/ehjci/jez166. [Epub ahead of print]

PMID:
31280289
18.

Impact of pulmonary endarterectomy on pulmonary arterial wave propagation and reservoir function.

Su J, Hughes AD, Simonsen U, Nielsen-Kudsk JE, Parker KH, Howard LS, Mellemkjaer S.

Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H505-H516. doi: 10.1152/ajpheart.00181.2019. Epub 2019 Jun 21.

PMID:
31225986
20.

Development of a Yoga-Based Cardiac Rehabilitation (Yoga-CaRe) Programme for Secondary Prevention of Myocardial Infarction.

Chattopadhyay K, Chandrasekaran AM, Praveen PA, Manchanda SC, Madan K, Ajay VS, Singh K, Tillin T, Hughes AD, Chaturvedi N, Ebrahim S, Pocock S, Reddy KS, Tandon N, Prabhakaran D, Kinra S.

Evid Based Complement Alternat Med. 2019 May 2;2019:7470184. doi: 10.1155/2019/7470184. eCollection 2019.

21.

Augmentation index is not a proxy for wave reflection magnitude: mechanistic analysis using a computational model.

Heusinkveld MHG, Delhaas T, Lumens J, Huberts W, Spronck B, Hughes AD, Reesink KD.

J Appl Physiol (1985). 2019 Aug 1;127(2):491-500. doi: 10.1152/japplphysiol.00769.2018. Epub 2019 May 30.

22.

Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children.

Dangardt F, Charakida M, Georgiopoulos G, Chiesa ST, Rapala A, Wade KH, Hughes AD, Timpson NJ, Pateras K, Finer N, Sattar N, Davey Smith G, Lawlor DA, Deanfield JE.

Lancet Child Adolesc Health. 2019 Jul;3(7):474-481. doi: 10.1016/S2352-4642(19)30105-1. Epub 2019 May 21.

23.

Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study.

Chiesa ST, Masi S, Shipley MJ, Ellins EA, Fraser AG, Hughes AD, Patel RS, Khir AW, Halcox JP, Singh-Manoux A, Kivimaki M, Celermajer DS, Deanfield JE.

Eur Heart J. 2019 Jul 21;40(28):2300-2309. doi: 10.1093/eurheartj/ehz189.

24.

Improving haemodynamic optimization of cardiac resynchronization therapy for heart failure.

Sharp AJ, Sohaib SMA, Shun-Shin MJ, Pabari P, Willson K, Rajkumar C, Hughes AD, Kanagaratnam P, Mayet J, Whinnett ZI, Kyriacou AA, Francis DP.

Physiol Meas. 2019 May 1;40(4):04NT01. doi: 10.1088/1361-6579/ab152c.

PMID:
30933931
25.

Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes.

Smith LA, Melbourne A, Owen D, Cardoso MJ, Sudre CH, Tillin T, Sokolska M, Atkinson D, Chaturvedi N, Ourselin S, Hughes AD, Barkhof F, Jäger HR.

Eur Radiol. 2019 Oct;29(10):5549-5558. doi: 10.1007/s00330-019-06096-w. Epub 2019 Mar 18.

26.

Adaptations to Coronary Physiology in a Patient With Severe Aortic Stenosis and Complete Heart Block Undergoing Transcatheter Aortic Valve Replacement.

Michail M, Asrress KN, Cameron JD, Gooley R, McCormick LM, Hughes AD, Brown AJ.

JACC Cardiovasc Interv. 2019 Apr 8;12(7):687-689. doi: 10.1016/j.jcin.2019.01.215. Epub 2019 Mar 13. No abstract available.

PMID:
30878477
27.

Mathematical Modelling of Intravenous Thrombolysis in Acute Ischaemic stroke: Effects of Dose Regimens on Levels of Fibrinolytic Proteins and Clot Lysis Time.

Gu B, Piebalgs A, Huang Y, Longstaff C, Hughes AD, Chen R, Thom SA, Xu XY.

Pharmaceutics. 2019 Mar 7;11(3). pii: E111. doi: 10.3390/pharmaceutics11030111.

28.

Data on trajectories of measures of cardiovascular health in the Avon Longitudinal Study of Parents and Children (ALSPAC).

O'Keeffe LM, Simpkin AJ, Tilling K, Anderson EL, Hughes AD, Lawlor DA, Fraser A, Howe LD.

Data Brief. 2019 Jan 19;23:103687. doi: 10.1016/j.dib.2019.01.035. eCollection 2019 Apr.

29.

An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy.

Huang Y, Yu L, Ren J, Gu B, Longstaff C, Hughes AD, Thom SA, Xu XY, Chen R.

J Control Release. 2019 Apr 28;300:1-12. doi: 10.1016/j.jconrel.2019.02.033. Epub 2019 Feb 23.

PMID:
30807804
30.

A Double-Blind Placebo-Controlled Crossover Study of the Effect of Beetroot Juice Containing Dietary Nitrate on Aortic and Brachial Blood Pressure Over 24 h.

Kukadia S, Dehbi HM, Tillin T, Coady E, Chaturvedi N, Hughes AD.

Front Physiol. 2019 Feb 4;10:47. doi: 10.3389/fphys.2019.00047. eCollection 2019.

31.

Effectiveness and cost-effectiveness of a Yoga-based Cardiac Rehabilitation (Yoga-CaRe) program following acute myocardial infarction: Study rationale and design of a multi-center randomized controlled trial.

Chandrasekaran AM, Kinra S, Ajay VS, Chattopadhyay K, Singh K, Singh K, Praveen PA, Soni D, Devarajan R, Kondal D, Manchanda SC, Hughes AD, Chaturvedi N, Roberts I, Pocock S, Ebrahim S, Reddy KS, Tandon N, Prabhakaran D; Yoga-CaRe Trial Team.

Int J Cardiol. 2019 Apr 1;280:14-18. doi: 10.1016/j.ijcard.2019.01.012. Epub 2019 Jan 7.

PMID:
30661847
32.

Application of the DILEMMA score to improve lesion selection for invasive physiological assessment.

Michail M, Dehbi HM, Nerlekar N, Davies JE, Sharp ASP, Talwar S, Cameron JD, Brown AJ, Wong DT, Mathur A, Hughes AD, Narayan O.

Catheter Cardiovasc Interv. 2019 Sep 1;94(3):E96-E103. doi: 10.1002/ccd.28054. Epub 2019 Jan 2.

PMID:
30604558
33.

Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses.

Wade KH, Chiesa ST, Hughes AD, Chaturvedi N, Charakida M, Rapala A, Muthurangu V, Khan T, Finer N, Sattar N, Howe LD, Fraser A, Lawlor DA, Davey Smith G, Deanfield JE, Timpson NJ.

Circulation. 2018 Nov 13;138(20):2187-2201. doi: 10.1161/CIRCULATIONAHA.117.033278. Epub 2018 Jul 30.

34.

Effects of bariatric surgery on retinal microvascular architecture in obese patients.

Viljanen A, Soinio M, Cheung CY, Hannukainen JC, Karlsson HK, Wong TY, Hughes AD, Salminen P, Nuutila P, Vesti E, Tapp RJ.

Int J Obes (Lond). 2019 Sep;43(9):1675-1680. doi: 10.1038/s41366-018-0242-7. Epub 2018 Dec 5.

PMID:
30518825
35.

Left atrial function in heart failure with mid-range ejection fraction differs from that of heart failure with preserved ejection fraction: a 2D speckle-tracking echocardiographic study.

Al Saikhan L, Hughes AD, Chung WS, Alsharqi M, Nihoyannopoulos P.

Eur Heart J Cardiovasc Imaging. 2019 Mar 1;20(3):279-290. doi: 10.1093/ehjci/jey171.

36.

Submaximal exercise blood pressure and cardiovascular structure in adolescence.

Schultz MG, Park C, Fraser A, Howe LD, Jones S, Rapala A, Davey Smith G, Sharman JE, Lawlor DA, Chaturvedi N, Deanfield J, Hughes AD.

Int J Cardiol. 2019 Jan 15;275:152-157. doi: 10.1016/j.ijcard.2018.10.060. Epub 2018 Oct 19.

37.

A method for determining local pulse wave velocity in human ascending aorta from sequential ultrasound measurements of diameter and velocity.

Negoita M, Hughes AD, Parker KH, Khir AW.

Physiol Meas. 2018 Nov 26;39(11):114009. doi: 10.1088/1361-6579/aae8a0.

38.

Cardiovascular Risk Factors and White Matter Hyperintensities: Difference in Susceptibility in South Asians Compared With Europeans.

Sudre CH, Smith L, Atkinson D, Chaturvedi N, Ourselin S, Barkhof F, Hughes AD, Jäger HR, Cardoso MJ.

J Am Heart Assoc. 2018 Nov 6;7(21):e010533. doi: 10.1161/JAHA.118.010533.

39.

Elevated Blood Pressure in Adolescence Is Attributable to a Combination of Elevated Cardiac Output and Total Peripheral Resistance.

Park C, Fraser A, Howe LD, Jones S, Davey Smith G, Lawlor DA, Chaturvedi N, Hughes AD.

Hypertension. 2018 Nov;72(5):1103-1108. doi: 10.1161/HYPERTENSIONAHA.118.11925.

40.

Sex-specific trajectories of measures of cardiovascular health during childhood and adolescence: A prospective cohort study.

O'Keeffe LM, Simpkin AJ, Tilling K, Anderson EL, Hughes AD, Lawlor DA, Fraser A, Howe LD.

Atherosclerosis. 2018 Nov;278:190-196. doi: 10.1016/j.atherosclerosis.2018.09.030. Epub 2018 Sep 27.

PMID:
30296724
41.

Cerebral Blood Flow and Cognitive Functioning in a Community-Based, Multi-Ethnic Cohort: The SABRE Study.

Leeuwis AE, Smith LA, Melbourne A, Hughes AD, Richards M, Prins ND, Sokolska M, Atkinson D, Tillin T, Jäger HR, Chaturvedi N, van der Flier WM, Barkhof F.

Front Aging Neurosci. 2018 Sep 18;10:279. doi: 10.3389/fnagi.2018.00279. eCollection 2018.

42.

Birth weight and cardiac function assessed by echocardiography in adolescence: Avon Longitudinal Study of Parents and Children.

Timpka S, Hughes AD, Chaturvedi N, Franks PW, Lawlor DA, Rich-Edwards JW, Fraser A.

Ultrasound Obstet Gynecol. 2019 Aug;54(2):225-231. doi: 10.1002/uog.20128.

43.

Hypertensive Disorders During Pregnancy and Offspring Retinal Microvasculature During Adolescence.

Magnus MC, Hughes AD, Williams C, Chaturvedi N, Catov J, Fraser A.

J Am Coll Cardiol. 2018 Sep 11;72(11):1318-1320. doi: 10.1016/j.jacc.2018.06.057. No abstract available.

44.

Early vascular damage from smoking and alcohol in teenage years: the ALSPAC study.

Charakida M, Georgiopoulos G, Dangardt F, Chiesa ST, Hughes AD, Rapala A, Davey Smith G, Lawlor D, Finer N, Deanfield JE.

Eur Heart J. 2019 Jan 21;40(4):345-353. doi: 10.1093/eurheartj/ehy524.

PMID:
30169581
45.

Early development and substrate twine selection for the cultivation of Sargassum muticum (Yendo) Fensholt under laboratory conditions.

Le HN, Hughes AD, Kerrison PD.

J Appl Phycol. 2018;30(4):2475-2483. doi: 10.1007/s10811-018-1459-5. Epub 2018 Apr 23.

46.

Regression of left ventricular hypertrophy provides an additive physiological benefit following treatment of aortic stenosis: Insights from serial coronary wave intensity analysis.

Broyd CJ, Rigo F, Nijjer S, Sen S, Petraco R, Al-Lamee R, Foin N, Chukwuemeka A, Anderson J, Parker J, Malik IS, Mikhail GW, Francis DP, Parker K, Hughes AD, Mayet J, Davies JE.

Acta Physiol (Oxf). 2018 Dec;224(4):e13109. doi: 10.1111/apha.13109. Epub 2018 Aug 3.

47.

Nitric Oxide Attenuates Arterial Pulse Wave Reflection in a Vasodilator Responding Pulmonary Arterial Hypertension Patient.

Su J, Hughes AD, Simonsen U, Howard LS.

Circ Cardiovasc Interv. 2018 Mar;11(3):e006242. doi: 10.1161/CIRCINTERVENTIONS.117.006242. No abstract available.

PMID:
29870387
48.

Distinct impacts of heart rate and right atrial-pacing on left atrial mechanical activation and optimal AV delay in CRT.

Kyriacou A, Rajkumar CA, Pabari PA, Sohaib SMA, Willson K, Peters NS, Lim PB, Kanagaratnam P, Hughes AD, Mayet J, Whinnett ZI, Francis DP.

Pacing Clin Electrophysiol. 2018 Jun 1. doi: 10.1111/pace.13401. [Epub ahead of print]

49.

Patterns of adiposity, vascular phenotypes and cognitive function in the 1946 British Birth Cohort.

Masi S, Georgiopoulos G, Khan T, Johnson W, Wong A, Charakida M, Whincup P, Hughes AD, Richards M, Hardy R, Deanfield J.

BMC Med. 2018 May 28;16(1):75. doi: 10.1186/s12916-018-1059-x.

50.

Multicenter Randomized Controlled Crossover Trial Comparing Hemodynamic Optimization Against Echocardiographic Optimization of AV and VV Delay of Cardiac Resynchronization Therapy: The BRAVO Trial.

Whinnett ZI, Sohaib SMA, Mason M, Duncan E, Tanner M, Lefroy D, Al-Obaidi M, Ellery S, Leyva-Leon F, Betts T, Dayer M, Foley P, Swinburn J, Thomas M, Khiani R, Wong T, Yousef Z, Rogers D, Kalra PR, Dhileepan V, March K, Howard J, Kyriacou A, Mayet J, Kanagaratnam P, Frenneaux M, Hughes AD, Francis DP.

JACC Cardiovasc Imaging. 2019 Aug;12(8 Pt 1):1407-1416. doi: 10.1016/j.jcmg.2018.02.014. Epub 2018 May 16.

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