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Items: 1 to 50 of 184

1.

Lung Microbiome is Influenced by the Environment and Asthmatic Status in an Equine Model of Asthma.

Fillion-Bertrand G, Dickson RP, Boivin R, Lavoie JP, Huffnagle GB, Leclere M.

Am J Respir Cell Mol Biol. 2018 Sep 5. doi: 10.1165/rcmb.2017-0228OC. [Epub ahead of print]

PMID:
30183323
2.

Symptom-related sputum microbiota in stable chronic obstructive pulmonary disease.

Diao W, Shen N, Du Y, Erb-Downward JR, Sun X, Guo C, Ke Q, Huffnagle GB, Gyetko MR, He B.

Int J Chron Obstruct Pulmon Dis. 2018 Jul 30;13:2289-2299. doi: 10.2147/COPD.S167618. eCollection 2018.

3.

Lung Dysbiosis, Inflammation, and Injury in Hematopoietic Cell Transplantation.

O'Dwyer DN, Zhou X, Wilke CA, Xia M, Falkowski NR, Norman KC, Arnold KB, Huffnagle GB, Murray S, Erb-Downward JR, Yanik GA, Moore BB, Dickson RP.

Am J Respir Crit Care Med. 2018 Jun 7. doi: 10.1164/rccm.201712-2456OC. [Epub ahead of print]

PMID:
29878854
4.

The Lung Microbiota of Healthy Mice Are Highly Variable, Cluster by Environment, and Reflect Variation in Baseline Lung Innate Immunity.

Dickson RP, Erb-Downward JR, Falkowski NR, Hunter EM, Ashley SL, Huffnagle GB.

Am J Respir Crit Care Med. 2018 Aug 15;198(4):497-508. doi: 10.1164/rccm.201711-2180OC.

PMID:
29533677
5.

Genome Sequences of 12 Pseudomonas lundensis Strains Isolated from the Lungs of Humans.

Scales BS, Erb-Downward JR, Falkowski NR, LiPuma JJ, Huffnagle GB.

Genome Announc. 2018 Feb 15;6(7). pii: e01461-17. doi: 10.1128/genomeA.01461-17.

6.

Bacterial Dissemination to the Brain in Sepsis.

Singer BH, Dickson RP, Denstaedt SJ, Newstead MW, Kim K, Falkowski NR, Erb-Downward JR, Schmidt TM, Huffnagle GB, Standiford TJ.

Am J Respir Crit Care Med. 2018 Mar 15;197(6):747-756. doi: 10.1164/rccm.201708-1559OC.

PMID:
29232157
7.

Reply: Clinical Metagenomics for the Diagnosis of Hospital-acquired Infections: Promises and Hurdles.

Pendleton KM, Erb-Downward JR, Bao Y, Branton WR, Falkowski NR, Newton DW, Huffnagle GB, Dickson RP.

Am J Respir Crit Care Med. 2017 Dec 15;196(12):1618-1619. doi: 10.1164/rccm.201706-1144LE. No abstract available.

PMID:
28679063
8.

Rapid Pathogen Identification in Bacterial Pneumonia Using Real-Time Metagenomics.

Pendleton KM, Erb-Downward JR, Bao Y, Branton WR, Falkowski NR, Newton DW, Huffnagle GB, Dickson RP.

Am J Respir Crit Care Med. 2017 Dec 15;196(12):1610-1612. doi: 10.1164/rccm.201703-0537LE. No abstract available.

PMID:
28475350
9.

The significance of Candida in the human respiratory tract: our evolving understanding.

Pendleton KM, Huffnagle GB, Dickson RP.

Pathog Dis. 2017 Apr 1;75(3). doi: 10.1093/femspd/ftx029. Review.

PMID:
28423168
10.

The microbiome in respiratory medicine: current challenges and future perspectives.

Faner R, Sibila O, Agustí A, Bernasconi E, Chalmers JD, Huffnagle GB, Manichanh C, Molyneaux PL, Paredes R, Pérez Brocal V, Ponomarenko J, Sethi S, Dorca J, Monsó E.

Eur Respir J. 2017 Apr 12;49(4). pii: 1602086. doi: 10.1183/13993003.02086-2016. Print 2017 Apr. Review.

11.

Bacterial Topography of the Healthy Human Lower Respiratory Tract.

Dickson RP, Erb-Downward JR, Freeman CM, McCloskey L, Falkowski NR, Huffnagle GB, Curtis JL.

MBio. 2017 Feb 14;8(1). pii: e02287-16. doi: 10.1128/mBio.02287-16.

12.

Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis.

Huang Y, Ma SF, Espindola MS, Vij R, Oldham JM, Huffnagle GB, Erb-Downward JR, Flaherty KR, Moore BB, White ES, Zhou T, Li J, Lussier YA, Han MK, Kaminski N, Garcia JGN, Hogaboam CM, Martinez FJ, Noth I; COMET-IPF Investigators.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):208-219. doi: 10.1164/rccm.201607-1525OC.

13.

Role of interferon-γ and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice.

McDermott AJ, Falkowski NR, McDonald RA, Frank CR, Pandit CR, Young VB, Huffnagle GB.

Immunology. 2017 Apr;150(4):468-477. doi: 10.1111/imm.12700. Epub 2017 Jan 30.

14.

The respiratory tract microbiome and lung inflammation: a two-way street.

Huffnagle GB, Dickson RP, Lukacs NW.

Mucosal Immunol. 2017 Mar;10(2):299-306. doi: 10.1038/mi.2016.108. Epub 2016 Dec 14. Review.

15.

CCR2 mediates Helicobacter pylori-induced immune tolerance and contributes to mucosal homeostasis.

Sun X, Zhang M, El-Zaatari M, Huffnagle GB, Kao JY.

Helicobacter. 2017 Apr;22(2). doi: 10.1111/hel.12366. Epub 2016 Dec 8.

16.

Dysbiosis in the intensive care unit: Microbiome science coming to the bedside.

Kitsios GD, Morowitz MJ, Dickson RP, Huffnagle GB, McVerry BJ, Morris A.

J Crit Care. 2017 Apr;38:84-91. doi: 10.1016/j.jcrc.2016.09.029. Epub 2016 Oct 11. Review.

17.

A tale of two sites: how inflammation can reshape the microbiomes of the gut and lungs.

Scales BS, Dickson RP, Huffnagle GB.

J Leukoc Biol. 2016 Nov;100(5):943-950. Epub 2016 Jun 30. Review.

18.

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome.

Dickson RP, Singer BH, Newstead MW, Falkowski NR, Erb-Downward JR, Standiford TJ, Huffnagle GB.

Nat Microbiol. 2016 Jul 18;1(10):16113. doi: 10.1038/nmicrobiol.2016.113.

19.

Another piece in the 'research mosaic' that describes the role of the lung microbiome in COPD.

Huffnagle GB.

Thorax. 2016 Sep;71(9):777-8. doi: 10.1136/thoraxjnl-2015-207415. Epub 2016 Jul 19. No abstract available.

PMID:
27435609
20.

Understanding the role of the microbiome in chronic obstructive pulmonary disease: principles, challenges, and future directions.

Huang YJ, Erb-Downward JR, Dickson RP, Curtis JL, Huffnagle GB, Han MK.

Transl Res. 2017 Jan;179:71-83. doi: 10.1016/j.trsl.2016.06.007. Epub 2016 Jun 23. Review.

21.

The respiratory microbiome: an underappreciated player in the human response to inhaled pollutants?

Adar SD, Huffnagle GB, Curtis JL.

Ann Epidemiol. 2016 May;26(5):355-9. doi: 10.1016/j.annepidem.2016.03.010. Epub 2016 Apr 7. Review.

22.

Comparative genomics of Pseudomonas fluorescens subclade III strains from human lungs.

Scales BS, Erb-Downward JR, Huffnagle IM, LiPuma JJ, Huffnagle GB.

BMC Genomics. 2015 Dec 7;16:1032. doi: 10.1186/s12864-015-2261-2.

23.

The Microbiome and the Respiratory Tract.

Dickson RP, Erb-Downward JR, Martinez FJ, Huffnagle GB.

Annu Rev Physiol. 2016;78:481-504. doi: 10.1146/annurev-physiol-021115-105238. Epub 2015 Nov 2. Review.

24.

Interleukin-23 (IL-23), independent of IL-17 and IL-22, drives neutrophil recruitment and innate inflammation during Clostridium difficile colitis in mice.

McDermott AJ, Falkowski NR, McDonald RA, Pandit CR, Young VB, Huffnagle GB.

Immunology. 2016 Jan;147(1):114-24. doi: 10.1111/imm.12545. Epub 2015 Dec 2.

25.

Homeostasis and its disruption in the lung microbiome.

Dickson RP, Erb-Downward JR, Huffnagle GB.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1047-55. doi: 10.1152/ajplung.00279.2015. Epub 2015 Oct 2. Review.

26.

"B" for Bad, Beneficial, or Both? Lung Lymphoid Neogenesis in Chronic Obstructive Pulmonary Disease.

Curtis JL, Freeman CM, Huffnagle GB.

Am J Respir Crit Care Med. 2015 Sep 15;192(6):648-51. doi: 10.1164/rccm.201506-1230ED. No abstract available.

27.

Draft Genome Sequences of Five Pseudomonas fluorescens Subclade I and II Strains, Isolated from Human Respiratory Samples.

Scales BS, Erb-Downward JR, LiPuma JJ, Huffnagle GB.

Genome Announc. 2015 Jul 30;3(4). pii: e00837-15. doi: 10.1128/genomeA.00837-15.

28.

Intraalveolar Catecholamines and the Human Lung Microbiome.

Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB.

Am J Respir Crit Care Med. 2015 Jul 15;192(2):257-9. doi: 10.1164/rccm.201502-0326LE. No abstract available.

29.

The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease.

Dickson RP, Huffnagle GB.

PLoS Pathog. 2015 Jul 9;11(7):e1004923. doi: 10.1371/journal.ppat.1004923. eCollection 2015 Jul. Review. No abstract available.

30.

The bacterial microbiota in inflammatory lung diseases.

Huffnagle GB, Dickson RP.

Clin Immunol. 2015 Aug;159(2):177-82. doi: 10.1016/j.clim.2015.05.022. Epub 2015 Jun 26. Review.

31.

Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease.

Sze MA, Dimitriu PA, Suzuki M, McDonough JE, Campbell JD, Brothers JF, Erb-Downward JR, Huffnagle GB, Hayashi S, Elliott WM, Cooper J, Sin DD, Lenburg ME, Spira A, Mohn WW, Hogg JC.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):438-45. doi: 10.1164/rccm.201502-0223OC.

32.

Spatial Variation in the Healthy Human Lung Microbiome and the Adapted Island Model of Lung Biogeography.

Dickson RP, Erb-Downward JR, Freeman CM, McCloskey L, Beck JM, Huffnagle GB, Curtis JL.

Ann Am Thorac Soc. 2015 Jun;12(6):821-30. doi: 10.1513/AnnalsATS.201501-029OC.

33.

Analysis of the upper respiratory tract microbiotas as the source of the lung and gastric microbiotas in healthy individuals.

Bassis CM, Erb-Downward JR, Dickson RP, Freeman CM, Schmidt TM, Young VB, Beck JM, Curtis JL, Huffnagle GB.

MBio. 2015 Mar 3;6(2):e00037. doi: 10.1128/mBio.00037-15.

34.

Draft Genome Sequences of Seven Pseudomonas fluorescens Subclade III Strains Isolated from Cystic Fibrosis Patients.

Scales BS, Erb-Downward JR, Huffnagle IM, LiPuma JJ, Huffnagle GB.

Genome Announc. 2015 Jan 29;3(1). pii: e01285-14. doi: 10.1128/genomeA.01285-14.

35.

Application of a neutral community model to assess structuring of the human lung microbiome.

Venkataraman A, Bassis CM, Beck JM, Young VB, Curtis JL, Huffnagle GB, Schmidt TM.

MBio. 2015 Jan 20;6(1). pii: e02284-14. doi: 10.1128/mBio.02284-14.

36.

The role of Gr-1(+) cells and tumour necrosis factor-α signalling during Clostridium difficile colitis in mice.

McDermott AJ, Higdon KE, Muraglia R, Erb-Downward JR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB.

Immunology. 2015 Apr;144(4):704-16. doi: 10.1111/imm.12425.

37.

[Preparation of metagenomic DNA from bronchoalveolar lavage fluids of patients with chronic obstructive pulmonary diseases].

Wang J, Shen N, Du Y, Erb-Downward JR, Huffnagle GB, Gyetko MR, He B.

Wei Sheng Wu Xue Bao. 2014 Aug 4;54(8):943-9. Chinese.

PMID:
25345027
38.

Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice.

Sadighi Akha AA, McDermott AJ, Theriot CM, Carlson PE Jr, Frank CR, McDonald RA, Falkowski NR, Bergin IL, Young VB, Huffnagle GB.

Immunology. 2015 Apr;144(4):587-97. doi: 10.1111/imm.12414.

39.

Microbiology, genomics, and clinical significance of the Pseudomonas fluorescens species complex, an unappreciated colonizer of humans.

Scales BS, Dickson RP, LiPuma JJ, Huffnagle GB.

Clin Microbiol Rev. 2014 Oct;27(4):927-48. doi: 10.1128/CMR.00044-14. Review.

40.

Cell-associated bacteria in the human lung microbiome.

Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB.

Microbiome. 2014 Aug 18;2:28. doi: 10.1186/2049-2618-2-28. eCollection 2014.

41.

The role of the microbiome in exacerbations of chronic lung diseases.

Dickson RP, Martinez FJ, Huffnagle GB.

Lancet. 2014 Aug 23;384(9944):691-702. doi: 10.1016/S0140-6736(14)61136-3. Review.

42.

Analysis of culture-dependent versus culture-independent techniques for identification of bacteria in clinically obtained bronchoalveolar lavage fluid.

Dickson RP, Erb-Downward JR, Prescott HC, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB.

J Clin Microbiol. 2014 Oct;52(10):3605-13. doi: 10.1128/JCM.01028-14. Epub 2014 Jul 30.

43.

Role of GM-CSF in the inflammatory cytokine network that regulates neutrophil influx into the colonic mucosa during Clostridium difficile infection in mice.

McDermott AJ, Frank CR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB.

Gut Microbes. 2014 Jul 1;5(4):476-84. doi: 10.4161/gmic.29964. Epub 2014 Jul 21.

44.

Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.

El-Zaatari M, Chang YM, Zhang M, Franz M, Shreiner A, McDermott AJ, van der Sluijs KF, Lutter R, Grasberger H, Kamada N, Young VB, Huffnagle GB, Kao JY.

J Immunol. 2014 Jul 15;193(2):807-16. doi: 10.4049/jimmunol.1302913. Epub 2014 Jun 16.

45.

Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations.

Dickson RP, Erb-Downward JR, Freeman CM, Walker N, Scales BS, Beck JM, Martinez FJ, Curtis JL, Lama VN, Huffnagle GB.

PLoS One. 2014 May 15;9(5):e97214. doi: 10.1371/journal.pone.0097214. eCollection 2014.

46.

Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study.

Han MK, Zhou Y, Murray S, Tayob N, Noth I, Lama VN, Moore BB, White ES, Flaherty KR, Huffnagle GB, Martinez FJ; COMET Investigators.

Lancet Respir Med. 2014 Jul;2(7):548-56. doi: 10.1016/S2213-2600(14)70069-4. Epub 2014 Apr 21. Erratum in: Lancet Respir Med. 2014 Aug;2(8):e14.

47.

Promotion of lung health: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.

Camargo CA Jr, Budinger GR, Escobar GJ, Hansel NN, Hanson CK, Huffnagle GB, Buist AS.

Ann Am Thorac Soc. 2014 Apr;11 Suppl 3:S125-38. doi: 10.1513/AnnalsATS.201312-451LD. Review.

48.

The systemic inflammatory response to Clostridium difficile infection.

Rao K, Erb-Downward JR, Walk ST, Micic D, Falkowski N, Santhosh K, Mogle JA, Ring C, Young VB, Huffnagle GB, Aronoff DM.

PLoS One. 2014 Mar 18;9(3):e92578. doi: 10.1371/journal.pone.0092578. eCollection 2014.

49.

Towards an ecology of the lung: new conceptual models of pulmonary microbiology and pneumonia pathogenesis.

Dickson RP, Erb-Downward JR, Huffnagle GB.

Lancet Respir Med. 2014 Mar;2(3):238-46. doi: 10.1016/S2213-2600(14)70028-1.

50.

Increase in dietary fiber dampens allergic responses in the lung.

Huffnagle GB.

Nat Med. 2014 Feb;20(2):120-1. doi: 10.1038/nm.3472. No abstract available.

PMID:
24504401

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