Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51


Author Correction: Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging.

Choi J, Rakhilin N, Gadamsetty P, Joe DJ, Tabrizian T, Lipkin SM, Huffman DM, Shen X, Nishimura N.

Sci Rep. 2019 Sep 30;9(1):13992. doi: 10.1038/s41598-019-43805-3.


The enigmatic role of growth hormone in age-related diseases, cognition, and longevity.

Colon G, Saccon T, Schneider A, Cavalcante MB, Huffman DM, Berryman D, List E, Ikeno Y, Musi N, Bartke A, Kopchick J, Kirkland JL, Tchkonia T, Masternak MM.

Geroscience. 2019 Sep 4. doi: 10.1007/s11357-019-00096-w. [Epub ahead of print] Review.


Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells.

Morrison EJ, Champagne DP, Dzieciatkowska M, Nemkov T, Zimring JC, Hansen KC, Guan F, Huffman DM, Santambrogio L, D'Alessandro A.

Nutrients. 2019 Jun 14;11(6). pii: E1337. doi: 10.3390/nu11061337.


Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice.

Farias Quipildor GE, Mao K, Hu Z, Novaj A, Cui MH, Gulinello M, Branch CA, Gubbi S, Patel K, Moellering DR, Tarantini S, Kiss T, Yabluchanskiy A, Ungvari Z, Sonntag WE, Huffman DM.

Geroscience. 2019 Apr;41(2):185-208. doi: 10.1007/s11357-019-00065-3. Epub 2019 May 10.


Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling.

Gandy S, Huffman DM.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):5852-5854. doi: 10.1073/pnas.1901970116. Epub 2019 Mar 11. No abstract available.


Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans.

Walters RO, Arias E, Diaz A, Burgos ES, Guan F, Tiano S, Mao K, Green CL, Qiu Y, Shah H, Wang D, Hudgins AD, Tabrizian T, Tosti V, Shechter D, Fontana L, Kurland IJ, Barzilai N, Cuervo AM, Promislow DEL, Huffman DM.

Cell Rep. 2018 Oct 16;25(3):663-676.e6. doi: 10.1016/j.celrep.2018.09.065.


Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging.

Choi J, Rakhilin N, Gadamsetty P, Joe DJ, Tabrizian T, Lipkin SM, Huffman DM, Shen X, Nishimura N.

Sci Rep. 2018 Jul 20;8(1):10989. doi: 10.1038/s41598-018-29230-y. Erratum in: Sci Rep. 2019 Sep 30;9(1):13992.


Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice.

Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters RO, Delahaye F, Hubbard GB, Ikeno Y, Ejima K, Li P, Allison DB, Salimi-Moosavi H, Beltran PJ, Cohen P, Barzilai N, Huffman DM.

Nat Commun. 2018 Jun 19;9(1):2394. doi: 10.1038/s41467-018-04805-5.


Dietary Walnuts Protect Against Obesity-Driven Intestinal Stem Cell Decline and Tumorigenesis.

Guan F, Tabrizian T, Novaj A, Nakanishi M, Rosenberg DW, Huffman DM.

Front Nutr. 2018 May 31;5:37. doi: 10.3389/fnut.2018.00037. eCollection 2018.


40 YEARS of IGF1: IGF1: the Jekyll and Hyde of the aging brain.

Gubbi S, Quipildor GF, Barzilai N, Huffman DM, Milman S.

J Mol Endocrinol. 2018 Jul;61(1):T171-T185. doi: 10.1530/JME-18-0093. Epub 2018 May 8. Review.


Mesenteric visceral lipectomy using tissue liquefaction technology reverses insulin resistance and causes weight loss in baboons.

Andrew MS, Huffman DM, Rodriguez-Ayala E, Williams NN, Peterson RM, Bastarrachea RA.

Surg Obes Relat Dis. 2018 Jun;14(6):833-841. doi: 10.1016/j.soard.2018.03.004. Epub 2018 Mar 9.


A simplified characterization of S-adenosyl-l-methionine-consuming enzymes with 1-Step EZ-MTase: a universal and straightforward coupled-assay for in vitro and in vivo setting.

Burgos ES, Walters RO, Huffman DM, Shechter D.

Chem Sci. 2017 Sep 1;8(9):6601-6612. doi: 10.1039/c7sc02830j. Epub 2017 Jul 27.


Apc inactivation, but not obesity, synergizes with Pten deficiency to drive intestinal stem cell-derived tumorigenesis.

Tabrizian T, Wang D, Guan F, Hu Z, Beck AP, Delahaye F, Huffman DM.

Endocr Relat Cancer. 2017 Jun;24(6):253-265. doi: 10.1530/ERC-16-0536. Epub 2017 Mar 28.


Tunable somatosensory stimulation for selective sleep restriction studies in rodents.

Huffman DM, Staggs KE, Yaghouby F, Agarwal A, O'Hara BF, Donohue KD, Blalock EM, Sunderam S.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:1640-1643. doi: 10.1109/EMBC.2016.7591028.


Glucokinase mutation-a rare cause of recurrent hypoglycemia in adults: a case report and literature review.

Ajala ON, Huffman DM, Ghobrial II.

J Community Hosp Intern Med Perspect. 2016 Oct 26;6(5):32983. doi: 10.3402/jchimp.v6.32983. eCollection 2016.


Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience.

Huffman DM, Justice JN, Stout MB, Kirkland JL, Barzilai N, Austad SN.

J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1395-1406. Epub 2016 Aug 16.


The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research.

Milman S, Huffman DM, Barzilai N.

Cell Metab. 2016 Jun 14;23(6):980-989. doi: 10.1016/j.cmet.2016.05.014. Review.


Energetic interventions for healthspan and resiliency with aging.

Huffman DM, Schafer MJ, LeBrasseur NK.

Exp Gerontol. 2016 Dec 15;86:73-83. doi: 10.1016/j.exger.2016.05.012. Epub 2016 May 31. Review.


Relationships between Rodent White Adipose Fat Pads and Human White Adipose Fat Depots.

Chusyd DE, Wang D, Huffman DM, Nagy TR.

Front Nutr. 2016 Apr 19;3:10. doi: 10.3389/fnut.2016.00010. eCollection 2016. Review.


Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers.

Cobb LJ, Lee C, Xiao J, Yen K, Wong RG, Nakamura HK, Mehta HH, Gao Q, Ashur C, Huffman DM, Wan J, Muzumdar R, Barzilai N, Cohen P.

Aging (Albany NY). 2016 Apr;8(4):796-809. doi: 10.18632/aging.100943.


Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.

Huffman DM, Farias Quipildor G, Mao K, Zhang X, Wan J, Apontes P, Cohen P, Barzilai N.

Aging Cell. 2016 Feb;15(1):181-6. doi: 10.1111/acel.12415. Epub 2015 Nov 4.


Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity.

Milman S, Atzmon G, Huffman DM, Wan J, Crandall JP, Cohen P, Barzilai N.

Aging Cell. 2014 Aug;13(4):769-71. doi: 10.1111/acel.12213. Epub 2014 Mar 12.


Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice.

Huffman DM, Augenlicht LH, Zhang X, Lofrese JJ, Atzmon G, Chamberland JP, Mantzoros CS.

Cancer Prev Res (Phila). 2013 Mar;6(3):177-87. doi: 10.1158/1940-6207.CAPR-12-0414.


The critical role of metabolic pathways in aging.

Barzilai N, Huffman DM, Muzumdar RH, Bartke A.

Diabetes. 2012 Jun;61(6):1315-22. doi: 10.2337/db11-1300. Review.


Distinguishing between longevity and buffered-deleterious genotypes for exceptional human longevity: the case of the MTP gene.

Huffman DM, Deelen J, Ye K, Bergman A, Slagboom EP, Barzilai N, Atzmon G.

J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1153-60. doi: 10.1093/gerona/gls103. Epub 2012 Apr 10.


How professional nurses working in hospital environments experience moral distress: a systematic review.

Huffman DM, Rittenmeyer L.

Crit Care Nurs Clin North Am. 2012 Mar;24(1):91-100. doi: 10.1016/j.ccell.2012.01.004. Epub 2012 Feb 3. Review.


Exercise to the rescue.

Huffman DM, Calvert JW.

J Physiol. 2011 Dec 15;589(Pt 24):5919-20. doi: 10.1113/jphysiol.2011.221879. No abstract available.


Editorial comment to inhibition of cortactin and SIRT1 expression attenuates migration and invasion of prostate cancer DU145 cells.

Huffman DM.

Int J Urol. 2012 Jan;19(1):79-80. doi: 10.1111/j.1442-2042.2011.02915.x. Epub 2011 Nov 15. No abstract available.


Exercise as a calorie restriction mimetic: implications for improving healthy aging and longevity.

Huffman DM.

Interdiscip Top Gerontol. 2010;37:157-74. doi: 10.1159/000320000. Epub 2010 Aug 10. Review.


Contribution of adipose tissue to health span and longevity.

Huffman DM, Barzilai N.

Interdiscip Top Gerontol. 2010;37:1-19. doi: 10.1159/000319991. Epub 2010 Aug 10. Review.


Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice.

Muzumdar RH, Huffman DM, Calvert JW, Jha S, Weinberg Y, Cui L, Nemkal A, Atzmon G, Klein L, Gundewar S, Ji SY, Lavu M, Predmore BL, Lefer DJ.

Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):1940-8. doi: 10.1161/ATVBAHA.110.205997. Epub 2010 Jul 22.


Aging per se increases the susceptibility to free fatty acid-induced insulin resistance.

Einstein FH, Huffman DM, Fishman S, Jerschow E, Heo HJ, Atzmon G, Schechter C, Barzilai N, Muzumdar RH.

J Gerontol A Biol Sci Med Sci. 2010 Aug;65(8):800-8. doi: 10.1093/gerona/glq078. Epub 2010 May 26.


Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians.

Atzmon G, Cho M, Cawthon RM, Budagov T, Katz M, Yang X, Siegel G, Bergman A, Huffman DM, Schechter CB, Wright WE, Shay JW, Barzilai N, Govindaraju DR, Suh Y.

Proc Natl Acad Sci U S A. 2010 Jan 26;107 Suppl 1:1710-7. doi: 10.1073/pnas.0906191106. Epub 2009 Nov 13.


Humanin: a novel central regulator of peripheral insulin action.

Muzumdar RH, Huffman DM, Atzmon G, Buettner C, Cobb LJ, Fishman S, Budagov T, Cui L, Einstein FH, Poduval A, Hwang D, Barzilai N, Cohen P.

PLoS One. 2009 Jul 22;4(7):e6334. doi: 10.1371/journal.pone.0006334.


Continuous subcutaneous pramlintide infusion therapy in patients with type 1 diabetes: observations from a pilot study.

Huffman DM, McLean GW, Seagrove MA.

Endocr Pract. 2009 Nov-Dec;15(7):689-95. doi: 10.4158/EP09044.ORR1.


Role of visceral adipose tissue in aging.

Huffman DM, Barzilai N.

Biochim Biophys Acta. 2009 Oct;1790(10):1117-23. doi: 10.1016/j.bbagen.2009.01.008. Epub 2009 Jan 31. Review.


Enhanced activation of a "nutrient-sensing" pathway with age contributes to insulin resistance.

Einstein FH, Fishman S, Bauman J, Thompson RF, Huffman DM, Atzmon G, Barzilai N, Muzumdar RH.

FASEB J. 2008 Oct;22(10):3450-7. doi: 10.1096/fj.08-109041. Epub 2008 Jun 19.


Visceral adipose tissue modulates mammalian longevity.

Muzumdar R, Allison DB, Huffman DM, Ma X, Atzmon G, Einstein FH, Fishman S, Poduval AD, McVei T, Keith SW, Barzilai N.

Aging Cell. 2008 Jun;7(3):438-40. doi: 10.1111/j.1474-9726.2008.00391.x. Epub 2008 Mar 18.


Effect of exercise and calorie restriction on biomarkers of aging in mice.

Huffman DM, Moellering DR, Grizzle WE, Stockard CR, Johnson MS, Nagy TR.

Am J Physiol Regul Integr Comp Physiol. 2008 May;294(5):R1618-27. doi: 10.1152/ajpregu.00890.2007. Epub 2008 Mar 5.


SIRT1 is significantly elevated in mouse and human prostate cancer.

Huffman DM, Grizzle WE, Bamman MM, Kim JS, Eltoum IA, Elgavish A, Nagy TR.

Cancer Res. 2007 Jul 15;67(14):6612-8. Erratum in: Cancer Res. 2007 Sep 1;67(17):8423.


Cancer progression in the transgenic adenocarcinoma of mouse prostate mouse is related to energy balance, body mass, and body composition, but not food intake.

Huffman DM, Johnson MS, Watts A, Elgavish A, Eltoum IA, Nagy TR.

Cancer Res. 2007 Jan 1;67(1):417-24. Epub 2006 Dec 21.


Comparison of the Lunar DPX-L and Prodigy dual-energy X-ray absorptiometers for assessing total and regional body composition.

Huffman DM, Landy NM, Potter E, Nagy TR, Gower BA.

Int J Body Compos Res. 2005 Jan 1;3(1):25-30.


Effect of n-3 fatty acids on free tryptophan and exercise fatigue.

Huffman DM, Altena TS, Mawhinney TP, Thomas TR.

Eur J Appl Physiol. 2004 Aug;92(4-5):584-91. Epub 2004 Mar 30.


Differential effects of the incorporation of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) on the binding of the transcription factors, AP-1 and TFIID, to their cognate target DNA sequences.

Staschke KA, Richardson KK, Mabry TE, Baxter AJ, Scheuring JC, Huffman DM, Smith WC, Richardson FC, Colacino JM.

Nucleic Acids Res. 1996 Nov 1;24(21):4111-6.


Therapeutic handling techniques for the infant affected by cocaine.

Huffman DM, Price BK, Langel L.

Neonatal Netw. 1994 Aug;13(5):9-13.


An evaluation of 6 chromosomal mutagens in the AS52/XPRT mutation assay utilizing suspension culture and soft agar cloning.

Oberly TJ, Huffman DM, Scheuring JC, Garriott ML.

Mutat Res. 1993 Nov;319(3):179-87.


Creationism in Iowa.

Gerlovich JA, Goellner KE, Grant SC, Hanson RW, Huffman DM, McCollum CG, Tiffany LH, Weinberg SL.

Science. 1980 Jun 13;208(4449):1208, 1210-1. No abstract available.


Meiotic behavior in the mushroom Collybia maculata var. scorzonerea.

Huffman DM.

Mycologia. 1968 Mar-Apr;60(2):451-6. No abstract available.


The role of engulfment in the Dictyosteliaceae.

Huffman DM.

J Protozool. 1967 Nov;14(4):762-4. No abstract available.


Supplemental Content

Loading ...
Support Center