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Familial myeloid malignancies with germline TET2 mutation.

Duployez N, Goursaud L, Fenwarth L, Bories C, Marceau-Renaut A, Boyer T, Fournier E, Nibourel O, Roche-Lestienne C, Huet G, Beauvais D, Berthon C, Cambier N, Quesnel B, Preudhomme C.

Leukemia. 2019 Dec 11. doi: 10.1038/s41375-019-0675-6. [Epub ahead of print] No abstract available.


Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia.

Duployez N, Willekens C, Plo I, Marceau-Renaut A, de Botton S, Fenwarth L, Boyer T, Huet G, Nibourel O, Rose C, Nelken B, Quesnel B, Preudhomme C.

Blood. 2019 Dec 26;134(26):2414-2416. doi: 10.1182/blood.2019003206. No abstract available.


Straightforward extraction and selective bioconversion of high purity chitin from Bombyx eri larva: Toward an integrated insect biorefinery.

Huet G, Hadad C, Husson E, Laclef S, Lambertyn V, Araya Farias M, Jamali A, Courty M, Alayoubi R, Gosselin I, Sarazin C, Van Nhien AN.

Carbohydr Polym. 2020 Jan 15;228:115382. doi: 10.1016/j.carbpol.2019.115382. Epub 2019 Sep 28.


Gemcitabine-induced epithelial-mesenchymal transition-like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal-like phenotype.

El Amrani M, Corfiotti F, Corvaisier M, Vasseur R, Fulbert M, Skrzypczyk C, Deshorgues AC, Gnemmi V, Tulasne D, Lahdaoui F, Vincent A, Pruvot FR, Van Seuningen I, Huet G, Truant S.

Mol Carcinog. 2019 Nov;58(11):1985-1997. doi: 10.1002/mc.23090. Epub 2019 Aug 2.


Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.

Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P.

Cancers (Basel). 2018 May 8;10(5). pii: E140. doi: 10.3390/cancers10050140.


Functional assessment of creatine transporter in control and X-linked SLC6A8-deficient fibroblasts.

Joncquel-Chevalier Curt M, Bout MA, Fontaine M, Kim I, Huet G, Bekri S, Morin G, Moortgat S, Moerman A, Cuisset JM, Cheillan D, Vamecq J.

Mol Genet Metab. 2018 Apr;123(4):463-471. doi: 10.1016/j.ymgme.2018.02.010. Epub 2018 Feb 16.


Lactate Metabolism in Human Lung Tumors.

Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ.

Cell. 2017 Oct 5;171(2):358-371.e9. doi: 10.1016/j.cell.2017.09.019.


Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.

Gibault F, Bailly F, Corvaisier M, Coevoet M, Huet G, Melnyk P, Cotelle P.

ChemMedChem. 2017 Jun 21;12(12):954-961. doi: 10.1002/cmdc.201700063. Epub 2017 Apr 20.


Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse.

Corvaisier M, Bauzone M, Corfiotti F, Renaud F, El Amrani M, Monté D, Truant S, Leteurtre E, Formstecher P, Van Seuningen I, Gespach C, Huet G.

Oncotarget. 2016 Aug 30;7(35):56699-56712. doi: 10.18632/oncotarget.11057.


Non-Photoinduced Biological Properties of Verteporfin.

Gibault F, Corvaisier M, Bailly F, Huet G, Melnyk P, Cotelle P.

Curr Med Chem. 2016;23(11):1171-84. Review.


Genome-wide RNAi screen for nuclear actin reveals a network of cofilin regulators.

Dopie J, Rajakylä EK, Joensuu MS, Huet G, Ferrantelli E, Xie T, Jäälinoja H, Jokitalo E, Vartiainen MK.

J Cell Sci. 2015 Jul 1;128(13):2388-400. doi: 10.1242/jcs.169441. Epub 2015 May 28.


A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity.

Le Roux C, Huet G, Jauneau A, Camborde L, Trémousaygue D, Kraut A, Zhou B, Levaillant M, Adachi H, Yoshioka H, Raffaele S, Berthomé R, Couté Y, Parker JE, Deslandes L.

Cell. 2015 May 21;161(5):1074-1088. doi: 10.1016/j.cell.2015.04.025.


RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1.

Rajakylä EK, Viita T, Kyheröinen S, Huet G, Treisman R, Vartiainen MK.

Nat Commun. 2015 Jan 14;6:5978. doi: 10.1038/ncomms6978.


Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival.

Desurmont T, Skrypek N, Duhamel A, Jonckheere N, Millet G, Leteurtre E, Gosset P, Duchene B, Ramdane N, Hebbar M, Van Seuningen I, Pruvot FR, Huet G, Truant S.

Cancer Sci. 2015 Mar;106(3):262-9. doi: 10.1111/cas.12603. Epub 2015 Mar 5.


Breeding for resistances to Ralstonia solanacearum.

Huet G.

Front Plant Sci. 2014 Dec 12;5:715. doi: 10.3389/fpls.2014.00715. eCollection 2014. Review.


Protein adsorption can be reversibly switched on and off on mixed PEO/PAA brushes.

Delcroix MF, Laurent S, Huet GL, Dupont-Gillain CC.

Acta Biomater. 2015 Jan;11:68-79. doi: 10.1016/j.actbio.2014.09.010. Epub 2014 Sep 16.


Tumour biology of colorectal liver metastasis is a more important factor in survival than surgical margin clearance in the era of modern chemotherapy regimens.

Truant S, Séquier C, Leteurtre E, Boleslawski E, Elamrani M, Huet G, Duhamel A, Hebbar M, Pruvot FR.

HPB (Oxford). 2015 Feb;17(2):176-84. doi: 10.1111/hpb.12316. Epub 2014 Jul 9. Review.


The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications.

Flouriot G, Huet G, Demay F, Pakdel F, Boujrad N, Michel D.

Biochem J. 2014 Jul 15;461(2):257-68. doi: 10.1042/BJ20131240.


Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis.

Touil Y, Igoudjil W, Corvaisier M, Dessein AF, Vandomme J, Monté D, Stechly L, Skrypek N, Langlois C, Grard G, Millet G, Leteurtre E, Dumont P, Truant S, Pruvot FR, Hebbar M, Fan F, Ellis LM, Formstecher P, Van Seuningen I, Gespach C, Polakowska R, Huet G.

Clin Cancer Res. 2014 Feb 15;20(4):837-46. doi: 10.1158/1078-0432.CCR-13-1854. Epub 2013 Dec 9.


Steady-state nuclear actin levels are determined by export competent actin pool.

Skarp KP, Huet G, Vartiainen MK.

Cytoskeleton (Hoboken). 2013 Oct;70(10):623-34. doi: 10.1002/cm.21116. Epub 2013 Jul 11.


Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis.

Simeone R, Huet G, Constant P, Malaga W, Lemassu A, Laval F, Daffé M, Guilhot C, Chalut C.

PLoS One. 2013;8(3):e58954. doi: 10.1371/journal.pone.0058954. Epub 2013 Mar 11.


Design of mixed PEO/PAA brushes with switchable properties toward protein adsorption.

Delcroix MF, Huet GL, Conard T, Demoustier-Champagne S, Du Prez FE, Landoulsi J, Dupont-Gillain CC.

Biomacromolecules. 2013 Jan 14;14(1):215-25. doi: 10.1021/bm301637h. Epub 2012 Dec 27.


Actin-regulated feedback loop based on Phactr4, PP1 and cofilin maintains the actin monomer pool.

Huet G, Rajakylä EK, Viita T, Skarp KP, Crivaro M, Dopie J, Vartiainen MK.

J Cell Sci. 2013 Jan 15;126(Pt 2):497-507. doi: 10.1242/jcs.113241. Epub 2012 Nov 30.


Volumetric analysis of remnant liver regeneration after major hepatectomy in bevacizumab-treated patients: a case-matched study in 82 patients.

Millet G, Truant S, Leteurtre E, Hebbar M, Zerbib P, Huet G, Boleslawski E, Pruvot FR.

Ann Surg. 2012 Nov;256(5):755-61; discussion 761-2. doi: 10.1097/SLA.0b013e31827381ca.


Tumor size of hepatocellular carcinoma in noncirrhotic liver: a controversial predictive factor for outcome after resection.

Truant S, Boleslawski E, Duhamel A, Bouras AF, Louvet A, Febvay C, Leteurtre E, Huet G, Zerbib P, Dharancy S, Hebbar M, Pruvot FR.

Eur J Surg Oncol. 2012 Dec;38(12):1189-96. doi: 10.1016/j.ejso.2012.07.112. Epub 2012 Aug 3.


Nuclear actin levels as an important transcriptional switch.

Huet G, Skarp KP, Vartiainen MK.

Transcription. 2012 Sep-Oct;3(5):226-30. doi: 10.4161/trns.21062. Epub 2012 Sep 1.


Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected].

Ledeen RW, Wu G, André S, Bleich D, Huet G, Kaltner H, Kopitz J, Gabius HJ.

Ann N Y Acad Sci. 2012 Apr;1253:206-21. doi: 10.1111/j.1749-6632.2012.06479.x. Review. Erratum in: Ann N Y Acad Sci. 2012 Jul;1258:191.


Is coronary computed tomography angiography a resource sparing strategy in the risk stratification and evaluation of acute chest pain? Results of a randomized controlled trial.

Miller AH, Pepe PE, Peshock R, Bhore R, Yancy CC, Xuan L, Miller MM, Huet GR, Trimmer C, Davis R, Chason R, Kashner MT.

Acad Emerg Med. 2011 May;18(5):458-67. doi: 10.1111/j.1553-2712.2011.01066.x.


Pancreatic serous cystadenoma with compression of the main pancreatic duct: an unusual entity.

Truant S, Izgarevic D, Maunoury V, Buob D, Bulois P, Ernst O, Huet G, Zerbib P, Pruvot FR.

HPB Surg. 2011;2011:574378. doi: 10.1155/2011/574378. Epub 2011 Mar 14.


Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells.

Merlin J, Stechly L, de Beaucé S, Monté D, Leteurtre E, van Seuningen I, Huet G, Pigny P.

Oncogene. 2011 Jun 2;30(22):2514-25. doi: 10.1038/onc.2010.631. Epub 2011 Jan 24.


Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells.

Dessein AF, Stechly L, Jonckheere N, Dumont P, Monté D, Leteurtre E, Truant S, Pruvot FR, Figeac M, Hebbar M, Lecellier CH, Lesuffleur T, Dessein R, Grard G, Dejonghe MJ, de Launoit Y, Furuichi Y, Prévost G, Porchet N, Gespach C, Huet G.

Cancer Res. 2010 Jun 1;70(11):4644-54. doi: 10.1158/0008-5472.CAN-09-3828. Epub 2010 May 11.


The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias.

Mazars R, Gonzalez-de-Peredo A, Cayrol C, Lavigne AC, Vogel JL, Ortega N, Lacroix C, Gautier V, Huet G, Ray A, Monsarrat B, Kristie TM, Girard JP.

J Biol Chem. 2010 Apr 30;285(18):13364-71. doi: 10.1074/jbc.M109.072579. Epub 2010 Mar 3.


REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells.

Rafa L, Dessein AF, Devisme L, Buob D, Truant S, Porchet N, Huet G, Buisine MP, Lesuffleur T.

Int J Oncol. 2010 Mar;36(3):689-98.


Repression of the estrogen receptor-alpha transcriptional activity by the Rho/megakaryoblastic leukemia 1 signaling pathway.

Huet G, Mérot Y, Percevault F, Tiffoche C, Arnal JF, Boujrad N, Pakdel F, Métivier R, Flouriot G.

J Biol Chem. 2009 Dec 4;284(49):33729-39. doi: 10.1074/jbc.M109.045534. Epub 2009 Oct 13.


Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression.

Jonckheere N, Fauquette V, Stechly L, Saint-Laurent N, Aubert S, Susini C, Huet G, Porchet N, Van Seuningen I, Pigny P.

Br J Cancer. 2009 Aug 18;101(4):637-44. doi: 10.1038/sj.bjc.6605190.


A lipid profile typifies the Beijing strains of Mycobacterium tuberculosis: identification of a mutation responsible for a modification of the structures of phthiocerol dimycocerosates and phenolic glycolipids.

Huet G, Constant P, Malaga W, Lanéelle MA, Kremer K, van Soolingen D, Daffé M, Guilhot C.

J Biol Chem. 2009 Oct 2;284(40):27101-13. doi: 10.1074/jbc.M109.041939. Epub 2009 Aug 2.


Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking.

Morelle W, Stechly L, André S, Van Seuningen I, Porchet N, Gabius HJ, Michalski JC, Huet G.

Biol Chem. 2009 Jul;390(7):529-44. doi: 10.1515/BC.2009.075.


Galectin-4-regulated delivery of glycoproteins to the brush border membrane of enterocyte-like cells.

Stechly L, Morelle W, Dessein AF, André S, Grard G, Trinel D, Dejonghe MJ, Leteurtre E, Drobecq H, Trugnan G, Gabius HJ, Huet G.

Traffic. 2009 Apr;10(4):438-50. doi: 10.1111/j.1600-0854.2009.00882.x. Epub 2009 Jan 24.


Different outcomes of unliganded and liganded estrogen receptor-alpha on neurite outgrowth in PC12 cells.

Mérot Y, Ferrière F, Gailhouste L, Huet G, Percevault F, Saligaut C, Flouriot G.

Endocrinology. 2009 Jan;150(1):200-11. doi: 10.1210/en.2008-0449. Epub 2008 Sep 4.


Dynamics of estrogen receptor-mediated transcriptional activation of responsive genes in vivo: apprehending transcription in four dimensions.

Métivier R, Huet G, Gallais R, Finot L, Petit F, Tiffoche C, Mérot Y, LePéron C, Reid G, Penot G, Demay F, Gannon F, Flouriot G, Salbert G.

Adv Exp Med Biol. 2008;617:129-38. doi: 10.1007/978-0-387-69080-3_12. Review. No abstract available.


The phenolic glycolipid of Mycobacterium tuberculosis differentially modulates the early host cytokine response but does not in itself confer hypervirulence.

Sinsimer D, Huet G, Manca C, Tsenova L, Koo MS, Kurepina N, Kana B, Mathema B, Marras SA, Kreiswirth BN, Guilhot C, Kaplan G.

Infect Immun. 2008 Jul;76(7):3027-36. doi: 10.1128/IAI.01663-07. Epub 2008 Apr 28.


Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.

Gouyer V, Fontaine D, Dumont P, de Wever O, Fontayne-Devaud H, Leteurtre E, Truant S, Delacour D, Drobecq H, Kerckaert JP, de Launoit Y, Bracke M, Gespach C, Desseyn JL, Huet G.

Oncogene. 2008 Jul 3;27(29):4024-33. doi: 10.1038/onc.2008.42. Epub 2008 Mar 3. Review.


E-cadherin and beta-catenin mRNA levels throughout colon cancer progression.

Truant SC, Gouyer VP, Leteurtre EA, Zerimech F, Huet GM, Pruvot FR.

J Surg Res. 2008 Dec;150(2):212-8. doi: 10.1016/j.jss.2007.12.800. Epub 2008 Feb 11.


Loss of E-cadherin-mediated cell contacts reduces estrogen receptor alpha (ER alpha) transcriptional efficiency by affecting the respective contribution exerted by AF1 and AF2 transactivation functions.

Huet G, Mérot Y, Le Dily F, Kern L, Ferrière F, Saligaut C, Boujrad N, Pakdel F, Métivier R, Flouriot G.

Biochem Biophys Res Commun. 2008 Jan 11;365(2):304-9. Epub 2007 Nov 6.


Cysteine and serine proteases of synovial tissue in rheumatoid arthritis and osteoarthritis.

Solau-Gervais E, Zerimech F, Lemaire R, Fontaine C, Huet G, Flipo RM.

Scand J Rheumatol. 2007 Sep-Oct;36(5):373-7.


Protein splicing of SufB is crucial for the functionality of the Mycobacterium tuberculosis SUF machinery.

Huet G, Castaing JP, Fournier D, Daffé M, Saves I.

J Bacteriol. 2006 May;188(9):3412-4.


Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells.

Delacour D, Gouyer V, Zanetta JP, Drobecq H, Leteurtre E, Grard G, Moreau-Hannedouche O, Maes E, Pons A, André S, Le Bivic A, Gabius HJ, Manninen A, Simons K, Huet G.

J Cell Biol. 2005 May 9;169(3):491-501.


GC/MS identification and quantification of constituents of bacterial lipids and glycoconjugates obtained after methanolysis as heptafluorobutyrate derivatives.

Bohin A, Bouchart F, Richet C, Kol O, Leroy Y, Timmerman P, Huet G, Bohin JP, Zanetta JP.

Anal Biochem. 2005 May 15;340(2):231-44.


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